Neonatology

  • Research Faculty

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    Section Chief

    A photo of Jeffrey Whitsett.

    Jeffrey A. Whitsett, MD Co-Director, Perinatal Institute

    investigates the hierarchy of transcriptional controls and signaling cascades which determine commitment of progenitor cells that produce the differentiated epithelial cells lining the primordial and mature respiratory tract. The goal of his research is to provide insight into the pathogenesis of acute and chronic lung disorders. The role of surfactant in innate host defense and lung function is also an ongoing interest.
    Visit the Whitsett Lab.

    513-803-2790
    jeffrey.whitsett@cchmc.org

    Jeffrey A. Whitsett, MD

    Co-Director, Perinatal Institute

    Chief, Section of Neonatology, Perinatal and Pulmonary Biology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-803-2790

    Fax: 513-636-7868

    Email: jeffrey.whitsett@cchmc.org

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    Specialties

    Cystic fibrosis research; lung morphogenesis; control of gene expression in the respiratory epithelium; gene delivery and therapy 

    Visit the Whitsett Lab.

    Biography

    Jeffrey A. Whitsett, MD, is chief of the Section of Neonatology, Perinatal and Pulmonary Biology at Cincinnati Children's Hospital Medical Center.

    Dr. Whitsett received his medical degree from Columbia University, in New York, and has been a faculty member since 1977. He is internationally known for his research in pulmonary medicine, as well as for his clinical expertise in neonatology.

    Dr. Whitsett has made a series of groundbreaking contributions in pulmonary medicine. His major pioneering work has been on surfactant proteins A, B, C and D, cloning their genes, and clarifying their roles in lung development.

    Throughout his career, Dr. Whitsett has had the remarkable ability to move from molecular biology, to animal models, to diagnosis and therapy of human disease. He played a critical role in making surfactant protein replacement a routine tool for treating immature lungs and respiratory distress syndrome in premature infants. His laboratory has contributed to the identification of a number of genes critical for lung formation and function. Mutations in genes regulating surfactant homeostasis were shown to cause acute and chronic lung disease in infants and adults.

    Dr. Whitsett is a member of the Institute of Medicine, National Academy of Sciences and is the recipient of the Mead Johnson Award, a National Institutes of Health (NIH) Merit Award, the first Julius Comroe Lectureship in Pulmonary Research from FASEB, the William Cooper Procter Award from Cincinnati Children's, the Amberson Lecture Award of the American Thoracic Society, the prestigious Daniel Drake Medal for scientific contributions from the University of Cincinnati College of Medicine, the International Arvo Ylppö Medal from the Finnish Foundation for Pediatric Research and the Grand Hamdan International Award on Neonatal Medicine from the United Arab Emirates.

    Dr. Whitsett is the author of more than 400 papers in both the basic science and clinical literature.

    Education and Training

    MD: Columbia University, New York, NY, 1973.

    Residency: Pediatrics, Mt. Sinai Hospital, New York City, 1974 to 1976.

    Fellowship: Neonatology, Children's Hospital Medical Center, University of Cincinnati College of Medicine, 1976 to 1977.

    Publications

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    Division Director

    A photo of James M. Greenberg.

    James M. Greenberg, MD Co-Director, Perinatal Institute

    investigates the developmental biology of pulmonary vascular development, including how vascular endothelial growth factor (VEGF) mediates pulmonary vascular, lymphatic and airway development. He studies how VEGF mediates organization of pulmonary vasculature during late fetal life as well as how certain proteins implicated in axonal guidance during central nervous system development also direct developmental processes in the lung.

    513-636-3149
    james.greenberg@cchmc.org

    James M. Greenberg, MD

    Co-Director, Perinatal Institute

    Director, Division of Neonatology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-3149

    Fax: 513-803-0968

    Email: james.greenberg@cchmc.org

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    Specialties

    Neonatal chronic lung disease; late preterm infant

    Education and Training

    MD: University of Illinois College of Medicine, Chicago, Ill., 1977-1981.

    Pediatric Internship and Residency: University of Minnesota Hospital and Clinic, Minneapolis, Minn., 1981-1984. Chief Resident, Department of Pediatrics, University of Minnesota Hospital and Clinic, Minneapolis, Minn., 1984.

    Fellowship: Immunology / Neonatology, University of Minnesota Hospital and Clinic, Minneapolis, Minn., 1985-1987; 1988-1989; visiting scientist, Medical Research Council Laboratory of Molecular Biology, Division of Protein and Nucleic Acid Chemistry, Cambridge, England.

    Certification: American Board of Pediatrics, 1988; subspecialty board, Neonatal / Perinatal Medicine, 1989.

    Publications

    View PubMed Publications
    A photo of Louis Muglia.

    Louis J. Muglia, MD, PhD Co-Director, Perinatal Institute

    is a pediatric endocrinologist whose research efforts seek to define the mechanisms controlling the timing for birth in humans to prevent or better treat human preterm labor. Recent efforts analyze the contribution of genetic determinants to preterm birth. A second area of investigation is elucidation of the molecular pathways involved in the behavioral and neuroendocrine responses to stress.
    Visit the Muglia Lab

    513-803-7902
    louis.muglia@cchmc.org

    Louis J. Muglia, MD, PhD

    Co-Director, Perinatal Institute

    Director, Center for Prevention of Preterm Birth

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-803-7902

    Email: louis.muglia@cchmc.org

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    Specialties

    Pediatric endocrinology

    Visit the Muglia Lab

    Biography

    Dr. Muglia has pioneered the in vivo analyses of regulation of the endocrine stress response and the molecular pathways leading to birth using novel genetically altered mutant mice. These studies have elucidated the importance of corticotropin-releasing hormone, glucocorticoids, and prostaglandins in neuroendocrine modulation, behavior, and perinatal adaptation.  These studies have evolved over the last decade to specifically focus on the mechanisms controlling the timing for birth in humans using genetics and comparative genomics. The composition of the biological clock metering the duration of human gestation remains a central question in reproductive biology. The goal of the Muglia laboratory is to understand the molecular timing machinery comprising this biological clock to prevent or better treat human preterm labor and delivery.

    Among Dr. Muglia’s achievements are more than 180 publications and many awards, including a Burroughs Wellcome Fund Career Development Award in the Biomedical Sciences, the Society of Pediatric Research Young Investigator Award, and election to the American Society for Clinical Investigation and Association of American Physicians. In 2010, Dr. Muglia was elected to Fellow in the American Association for the advancement of Science. He is an active member of the Society for Pediatric Research, Society for Neuroscience, and the Lawson Wilkins Pediatric Endocrine Society. Dr. Muglia currently serves as chair of the Board of Scientific Counselors for the Eunice Kennedy Shriver National Institute of Child Health and Human Development of the National Institutes of Health.  In 2013, Dr. Muglia was elected to membership in the Institute of Medicine of the National Academies.

    Education and Training

    BS: University of Michigan, Ann Arbor, MI, 1981.

    PhD: University of Chicago, Chicago, IL, 1986.

    MD: University of Chicago, Chicago, IL, 1988.

    Publications

    Grants

    Amygdala Glucocorticoid Receptor Function in Stress.  Principle Investigator. NIH/NIMH. Feb 2009-Dec 2014.

    Maternal Temperament, Stress, Inflammation and Preterm Birth. Multi-PI. NIH/NICHD. Sep 2013-Aug 2017.

    Genetic Analysis of Human Preterm Birth. Principle Investigator. March of Dimes. Mar 2005-Feb 2014.

    March of Dimes Prematurity Research Center Ohio Collaborative. Coordinating PI. March of Dimes. Jul 2013-Jun 2018.

    Burroughs Wellcome Fund Research Consortium on Preterm Birth. Director.  Burroughs Wellcome. Oct 2007-Sep 2014.

    Faculty

    A photo of Henry Akinbi.

    Henry T. Akinbi, MD Attending Neonatologist

    studies host defense proteins in innate defense of the lungs using gene-targeted mice. The role of lysozyme in: 1) lung infection; 2) inflammation and 3) anti-oxidant defense is a major focus of his research program.

    513-636-8915
    henry.akinbi@cchmc.org

    Henry T. Akinbi, MD

    Attending Neonatologist

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-8915

    Fax: 513-636-7868

    Email: henry.akinbi@cchmc.org

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    Specialties

    Neonatal infections; blood transfusions; role of Lysozyme in airway host defense

    Education and Training

    MD: University of Ife, Ile-Ife, Nigera, Africa, 1980.

    Residency: Pediatrics, University of North Carolina at Chapel Hill, 1988-1991.

    Neonatology Fellowship: Children's Hospital of Philadelphia, Philadelphia, PA, 1991-1994.

    Certification: General Pediatrics, 1991. Recertification, 1998. Newborn Medicine, 1995, Recertification, 2002.

    Publications

    View PubMed Publications
    A photo of Tanya Cahill.

    Tanya E. Cahill, MD Director, High-Risk Clinic

    is interested in high risk infant follow-up and neonatal abstinence syndrome.


    tanya.cahill@cchmc.org

    Tanya E. Cahill, MD

    Director, High-Risk Clinic

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Fax: 513-636-5454

    Email: tanya.cahill@cchmc.org

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    Specialties

    High risk infant follow up; neonatal abstinence syndrome

    Education and Training

    MD: University of Cincinnati, Cincinnati, OH 2000.

    Residency:
    Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 2000-2003.

    Fellowship:
    Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 2003-2006.

    Certification:
    Pediatrics, 2003; Neonatology, 2008.
    A photo of Michael Crossman.

    Michael W. Crossman, MD, PhD Attending Neonatologist

    focuses on intestinal function and host-microbial interactions, bioethics and neonatal palliative care.

    859-301-3850
    michael.crossman@cchmc.org

    Michael W. Crossman, MD, PhD

    Attending Neonatologist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 859-301-3850

    Fax: 859-301-2066

    Email: michael.crossman@cchmc.org

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    Specialties

    Intestinal function and host-microbial interactions; bioethics and neonatal palliative care

    Education and Training

    PhD: Biochemistry, St. Louis University, St. Louis, MO, 1985.

    MD: St. Louis University, St. Louis, MO, 1986.

    Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio, 1986-1989; Chief resident, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 1989-1990.

    Fellowship: Neonatal- Perinatal Medical Fellowship, Washington University School of Medicine, 1990-1993.

    Certification: Neonatal - Perinatal Medicine, 1995, 2003.

    Publications

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    A photo of Neera Goyal.

    Neera K. Goyal, MD, MSc Attending Physician, Division of Hospital Medicine

    studies the role of hospital and community-based interventions to improve outcomes among preterm and other high risk newborns. Approaches to preterm birth prevention through social determinants of health is also an ongoing interest.

    513-803-7836

    Neera K. Goyal, MD, MSc

    Attending Physician, Division of Hospital Medicine

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-7836

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    Specialties

    Clinical

    Hospital medicine; level 1 and level 2 nursery care

    Research

    Perinatal health services; home visiting; preterm birth

    Biography

    As a Robert Wood Johnson Foundation Clinical Scholar at the University of Pennsylvania (2009-2011), Dr. Goyal studied the impact of delivery volume, teaching affiliation, and patient insurance on adherence to guidelines for postpartum length of stay, as well as the impact of discharge timing on readmission risk. She also conducted research on the impact of late preterm birth on early childhood respiratory morbidity and physical development.

    She joined Cincinnati Children’s Hospital Medical Center in 2011 as a faculty member with a joint appointment in the Division of Neonatology and the Division of Hospital Medicine. In 2012 she received the BIRCWH K12 Award to evaluate the role of community-based home visiting to improve pregnancy and infant health outcomes. Currently, Dr. Goyal is studying programmatic effects on health care utilization in ED and primary care settings for full term and preterm infants.

    Education and Training

    BA: Emory University, Atlanta, GA, 2001.

    MD: University of Texas Southwestern Medical Center in Dallas, Dallas, TX, 2005.

    MSc: Health Policy Research, University of Pennsylvania, Philadelphia, PA, 2011. 

    Residency: Children's Hospital of Philadelphia, Philadelphia, PA, 2008.

    Publications

    View PubMed Publications.
    A photo of Beth Haberman.

    Beth E. Haberman, MD Senior Medical Director, Neonatal Services

    has special interests in the care of infants with congenital diaphragmatic hernia and follow-up care of premature and term infants with complex medical needs.

    513-636-5465
    beth.haberman@cchmc.org

    Beth E. Haberman, MD

    Senior Medical Director, Neonatal Services

    Medical Director, Newborn Intensive Care Unit (NICU)

    Medical Director, Neonatal Transport Program

    Associate Director, High-Risk Infant Follow-Up Program

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-5465

    Fax: 513-636-5846

    Email: beth.haberman@cchmc.org

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    Specialties

    CDH and infant follow-up; care of infants with congenital diaphragmatic hernia; follow-up care of premature and term infants with complex medical needs

    Education and Training

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 1996-1999.

    Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1993-1996.

    MD: University of Louisville, Louisville, KY, 1993.

    Publications

    View PubMed Publications
    A photo of Steven B. Hoath.

    Steven B. Hoath, MD

    has varied research interests including epidermal barrier development (in utero and postnatal), fetal and neonatal skin adaptation (skin/environment interactions), tissue engineering of human skin (in vitro systems), innate immune function (biology of vernix and skin proteomics), development of non-invasive skin-based sensors for brain monitoring and the role of the skin as a critical interface for health care delivery.

    513-803-0960
    steven.hoath@cchmc.org

    Steven B. Hoath, MD

    Academic Information

    Emeritus, UC Department of Pediatrics

    Phone: 513-803-0960

    Fax: 513-803-0969

    Email: steven.hoath@cchmc.org

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    Specialties

    Clinical Interests

    Clinical aspects of Dr Hoath’s work derive from an understanding of the basics of human skin development and the multiple roles of the skin in neonatal care. New perspectives on the skin as a sensory interface are central to this understanding as is the role of the skin as an accessible environmental interface which complements ‘internal’ medicine. This view of the skin provides a unique, pivotal, and powerful opportunity to effect evidence-based organizational change in healthcare delivery to newborns. This approach highlights the criticality of the interface between medicine and nursing and the importance of focus on the bedside for the development of a truly “personalized” or “individualized” medicine in the future.

    Research Interests

    Epidermal barrier development (in utero and postnatal); fetal and neonatal skin adaptation (skin/environment interactions); tissue engineering of human skin (in vitro systems); innate immune function (biology of vernix and skin proteomics); development of non-invasive skin-based sensors for brain monitoring; role of the skin as a critical interface for health care delivery.

    Biography

    Dr. Hoath graduated from Stanford University and the University of Hamburg, Germany with majors in biology and German studies. He received his MD from the University of California, Los Angeles and completed his pediatric residency and fellowship in neonatology at UCLA before joining Cincinnati Children’s Hospital Medical Center in 1984.

    He has a longstanding interest in the development of fetal and newborn skin and the multiple roles of the skin as a critical interface for healthcare delivery in the NICU. In 1994, he was one of 7 international investigators participating in the first joint effort by NASA and the National Institutes of Health to study the effect of spaceflight and zero gravity on mammalian pregnancy and fetal development. This work grounds the idea of the skin as the ‘biological spacesuit’ for the human body.

    He has authored multiple papers, chapters, and a book on neonatal skin development. He is an inventor on 5 patents awarded to Cincinnati Children’s Hospital Medical Center based on the biology of the multifunctional fetal skin ‘cream’, vernix caseosa. Recent work has focused on the logico-mathematical organization of human epidermis and the close embryological connection of the skin and the brain.

    Education and Training

    Certification: American Board of Pediatrics, June 1983; Neonatal-Perinatal Medicine, November, 1983.

    Adjunct Assistant Professor: Harbor UCLA Medical Center, Los Angeles, 1983.

    Residency: University of California, Los Angeles, 1977-79.

    Internship: Harbor-UCLA Medical Center, 1976-1977.

    MD: University of California, Los Angeles, CA, 1976.

    Fellowship: Neonatology, Harbor-UCLA, Los Angeles Medical Center, 1980-1982; Pathology, UCLA School of Medicine, 1973-1974.

    Baccalaureate: Stanford University, Biology & German Studies, 1972.

    Publications

    View PubMed Publications
    A photo of Alan Jobe.

    Alan H. Jobe, MD, PhD Director, Division of Perinatal Biology

    has a special research focus on surfactant physiology. Dr. Jobe is also interested in lung maturation and lung injury in the fetus and newborn, the use of antenatal corticosteroids, and lung injury with ventilation of the preterm infant.

    513-636-8563
    alan.jobe@cchmc.org

    Alan H. Jobe, MD, PhD

    Director, Division of Perinatal Biology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-8563

    Fax: 513-636-8691

    Email: alan.jobe@cchmc.org

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    Specialties

    Clinical Interests

    Clinical trials in neonatology; bronchopulmonary dysplasia

    Research Interests

    Lung maturation and lung injury in the fetus and newborn; use of antenatal corticosteroids; lung injury with ventilation of the preterm

    Education and Training

    MD: University of California, San Diego, 1973. 

    PhD: University of California, San Diego, CA, 1973. 

    Residency: University Hospital, University of California, San Diego, CA, 1974 to 1975.

    Fellowship: University of California, San Diego, CA, 1975 to 1977.

    Board Certified: Pediatrics and Neonatal-Perinatal Medicine.

    Publications

    View PubMed Publications
    A photo of Beth Ann Johnson.

    Beth Ann Johnson, MD, MA Attending Neonatologist, Neonatology and Pulmonary Biology

    has a research focus in perinatal cardiology, premature infants with congenital heart disease, fetal diagnosis, and simulation.

    513-636-3291
    beth_ann.johnson@cchmc.org

    Beth Ann Johnson, MD, MA

    Attending Neonatologist, Neonatology and Pulmonary Biology

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-3291

    Fax: 513-636-3952

    Email: beth_ann.johnson@cchmc.org

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    Specialties

    Cardiac intensive care; neonatology; premature infants with congenital heart disease; mechanical assist devices; fetal diagnosis; ethics

    Education and Training

    MD: University of Illinois.

    Residency:
    University of Texas Health Science Center at San Antonio.

    Fellowships: Neonatal / Perinatal, Children’s Hospital of Wisconsin; Pediatric Cardiology, Children’s Hospital of Wisconsin; Pediatric Critical Care, Children’s Hospital of Philadelphia.

    MA: Bioethics, Medical College of Wisconsin.

    Publications

    View PubMed Publications
    A photo of Suhas G. Kallapur.

    Suhas G. Kallapur, MD Director, Neonatology Continuing Medical Education

    is interested in understanding how the fetus copes with and adapts to infectious and inflammatory insults in utero e.g. exposure to chorioamnionitis. Dr. Kallapur’s research focus is to understand the pathogenesis of lung injury and systemic inflammatory responses in fetuses and newborns. His lab uses a sheep model and has begun some work in humans.
    Visit the Kallapur Lab.

    513-636-3879
    suhas.kallapur@cchmc.org

    Suhas G. Kallapur, MD

    Director, Neonatology Continuing Medical Education

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-3879

    Fax: 513-636-7868

    Email: suhas.kallapur@cchmc.org

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    Specialties

    Chorioamnionitis; bronchopulmonary dysplasia; respiratory distress syndrome; fetal immunity

    Education and Training

    MBBS: University of Bombay, India, 1984. 

    DCH: College of Physicians and Surgeons, Bombay, 1986.

    MD, Pediatrics: University of Bombay, India, 1986.

    Residency: University of Bombay, India, 1984-87.

    Residency: Children's Hospital of Michigan, Detroit, Michigan, 1988-90. 

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 1990-1993.

    Publications

    View PubMed Publications

    Grants

    Mechanisms of Fetal Inflammatory Response Syndrome Induced by Chorioamnionitis. Principal Investigator. National Institute of Child Health and Human Development. Feb 2009-Jan 2014. #R01 HD57869.
    A photo of Beena Kamath-Rayne.

    Beena D. Kamath-Rayne, MD, MPH Attending Neonatologist, Neonatology and Pulmonary Biology

    does clinical/translational research in preterm birth, fetal lung maturity and timing of delivery using biomarkers in amniotic fluid. She also has an interest in global health, and is on the Global Health Education Task Force. She is a master trainer for Helping Babies Breathe (HBB), a global curriculum in neonatal resuscitation, and is collaborating on several research studies of HBB around the world.

    513-803-1606
    beena.kamath-rayne@cchmc.org

    Beena D. Kamath-Rayne, MD, MPH

    Attending Neonatologist, Neonatology and Pulmonary Biology

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-1606

    Fax: 513-636-0171

    Email: beena.kamath-rayne@cchmc.org

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    Specialties

    Perinatal epidemiology and public health; global health

    Biography

    Dr. Kamath-Rayne is doing collaborative research with maternal-fetal medicine on preterm birth, fetal lung maturity, and biomarker discovery in amniotic fluid. She has received a BIRCWH K12 award to fund this research. She has published on neonatal outcomes after elective Cesarean section, and after documented fetal lung maturity. Her work was required reading for the Maintenance for Certification for the American Board of Obstetrics and Gynecology in 2010.

    Dr. Kamath-Rayne was a reviewer for the Helping Babies Breathe (HBB) global neonatal resuscitation curriculum, and is currently a Master Trainer.  She is collaborating on several studies of HBB around the world. With Dr. Alan Jobe, she is also a neonatal consultant for MANDATE (Maternal and Neonatal Directed Assessment of Technology), a project funded by the Bill and Melinda Gates Foundation to RTI International to inform the development of technologies to decrease maternal and neonatal mortality worldwide.

    Education and Training

    MD: Georgetown University, Washington, D.C., 2000.

    Residency: Children's Hospital Colorado/University of Colorado Health Sciences, Denver, Colorado, 2003.

    Fellowship: Children's Hospital Colorado/University of Colorado Health Sciences, Denver, Colorado, 2008.

    Publications

    View PubMed Publications

    Grants

    Novel amniotic fluid biomarkers to predict fetal lung maturity and clinical respiratory outcome. Principle Investigator. Jul 2011-Jun 2013.
    A photo of Heather C. Kaplan.

    Heather C. Kaplan, MD, MSCE Attending Neonatologist, Neonatology and Pulmonary Biology

    focuses on understanding variations in evidence-based care practices across hospitals and identifying strategies for increasing the implementation of evidence and other innovations into practice. She recently began a line of investigation aimed at building the evidence base for quality improvement so that QI can be used more effectively as a strategy for improving quality and patient outcomes.

    513-803-0478
    heather.kaplan@cchmc.org

    Heather C. Kaplan, MD, MSCE

    Attending Neonatologist, Neonatology and Pulmonary Biology

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0478

    Fax: 513-636-0171

    Email: heather.kaplan@cchmc.org

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    Specialties

    Heather Kaplan conducts research focusing on understanding variations in evidence-based care practices across hospitals and examining strategies for increasing the implementation of evidence into practice in perinatal care. She uses a systems lens to understand and ultimately change behavior at the individual, group, organizational, and environmental levels of the health care system.

    Biography

    Heather C. Kaplan, MD, MSCE, is passionate about improving the quality and safety of perinatal care and has a solid foundation in epidemiology and research fundamentals. Through her role in the Ohio Perinatal Quality Collaborative, she gained practical experience in the use of quality improvement methods to reduce preterm births and improve outcomes of preterm newborns in Ohio and have formed collaborative relationships with obstetrical and neonatal care providers across the state.

    Additionally she has an understanding care delivery in a complex system requires taking a multidisciplinary, multilevel approach. Her career includes didactic coursework in multidisciplinary theories and methods.

    Education and Training

    BA: Washington University, St. Louis, Missouri.

    MD: Northwestern University, Chicago, Illinois.

    Residency: Children's National Medical Center, Washington, DC.

    Fellowship: The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

    MSCE: University of Pennsylvania, Philadelphia, Pennsylvania.

    Publications

    View PubMed Publications
    A photo of Alan Kenny.

    Alan P. Kenny, MD, PhD

    studies the molecular mechanisms controlling the earliest stages of respiratory and digestive organ development, including the role of a pool of foregut progenitor cells in the ventral endoderm which are induced by FGF and BMP signals emanating from the cardiogenic mesenchyme.

    513-803-2224
    alan.kenny@cchmc.org

    Alan P. Kenny, MD, PhD

    Academic Information

    Instructor, UC Department of Pediatrics

    Phone: 513-803-2224

    Fax: 513-636-7868

    Email: alan.kenny@cchmc.org

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    Specialties

    Clinical Interests

    Neonatal care; neonatal lung disease; neonatal malformations and anomalies

    Research Interests

    Lung progenitor development; stem cell differentiation; fetal malformations

    Biography

    Alan P. Kenny, MD, PhD, focuses his research on elucidating the molecular mechanisms controlling the earliest stages of respiratory and digestive organ development. Available evidence suggests that early lung, liver, and pancreas lineages develop from a pool of foregut progenitor cells in the ventral endoderm. They are induced by FGF and BMP signals emanating from the cardiogenic mesenchyme during early somite stages of development through a mechanism that is highly conserved among vertebrates. Despite significant gains in our understanding of this process, fundamentally important questions remain unanswered. First, how are the common foregut organ progenitors specified? Second, how are FGF and BMP pathways spatiotemporally coordinated such that different organs are induced from the common foregut progenitor? A third and most intriguing question is - what are the endoderm genetic programs activated in response to induction from mesoderm that ultimately direct specific foregut organ development?

    These questions remain unanswered mostly due to experimental limitations inherent in mouse embryos, which are small and difficult to dissect at such an early stage. Dr. Kenny uses the experimental advantages of the large, externally developing, abundant Xenopus embryos to address these critical, unresolved issues. Specifically, Dr. Kenny is testing his hypothesis that cardiogenic FGF and BMP signaling of different durations induce different organs. Dr. Kenny’s microarray experiment to identify the endodermal genes induced very early in response to mesodermal signaling. Surprisingly, several negative regulators of BMP signaling were induced early by mesoderm signaling. My preliminary work suggests the hypothesis that BMP inhibitory feedback is a critical component induced during early foregut organ progenitor development. This work should ultimately increase our understanding of normal and abnormal early fetal organ development, lending further insight into foregut malformations such as tracheoesophageal fistula and congenital diaphragmatic hernia. Additionally, this work aims to offer better means to direct human embryonic stem cells toward more foregut organ-specific cell fates for therapeutic purposes.

    Education and Training

    PhD: Biology.

    MD: University of Rochester School of Medicine and Dentistry, Rochester, NY, 2002.

    Residency: Golisano Children’s Hospital at Strong, University of Rochester, Rochester, NY, 2002-2005.

    Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2005-2008.

    Certifications: In Pediatrics, 2007 American Board of Pediatrics; American Board of Pediatrics, Board Eligible in Neonatal-Perinatal Medicine, 2008.

    Publications

    View PubMed Publications
    A photo of Paul Kingma.

    Paul S. Kingma, MD, PhD Neonatal Director, Cincinnati Fetal Center

    investigates the role of the innate immune system in neonatal infection. Specific projects currently focus on the role of surfactant protein D in neonatal sepsis and acute respiratory distress syndrome and on neutrophil function in cystic fibrosis patients.

    513-636-2995
    paul.kingma@cchmc.org

    Paul S. Kingma, MD, PhD

    Neonatal Director, Cincinnati Fetal Center

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-2995

    Fax: 513-636-7868

    Email: paul.kingma@cchmc.org

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    Specialties

    Clinical Interests

    Neonatology; congenital diaphragmatic hernia; neonatal infection

    Research Interests

    Innate immune systems; surfactant protein D; neutrophil function in cystic fibrosis

    Education and Training

    Fellowship: Cincinnati Children's Hospital Medical Center, 2005.

    Residency: Cincinnati Children's Hospital Medical Center, 2003.

    PhD: Vanderbilt University, TN, 2000.

    MD: Vanderbilt University, TN, 2000.

    BS: Calvin College, MI, 1992.

    Publications

    A photo of Thomas Korfhagen.

    Thomas R. Korfhagen, MD, PhD Attending Pediatrician, Neonatology and Pulmonary Biology

    studies the roles and mechanisms whereby surfactant proteins A, B, D, Relm peptides and EGF receptor signaling control lung infections, inflammation and responses to lung injury. Translational studies assessing processes to reduce the extent of lung injury and remodeling in neonates and adults.

    513-636-7216
    thomas.korfhagen@cchmc.org

    Thomas R. Korfhagen, MD, PhD

    Attending Pediatrician, Neonatology and Pulmonary Biology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-7216

    Fax: 513-636-7868

    Email: thomas.korfhagen@cchmc.org

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    Specialties

    Clinical Interests

    Care of high-risk infants; pediatric patients with complex, long term medical problems

    Research Interests

    Roles and mechanisms whereby surfactant proteins A, B, D, Relm peptides and EGF-R signaling control lung infections, inflammation and responses to lung injury. Translational studies assessing processes to reduce the extent of lung injury and remodeling in neonates and adults.

    Education and Training

    BA: University of Cincinnati, Cincinnati, OH, 1972.

    PhD: University of Cincinnati, Cincinnati, OH, 1976.

    MD: University of Cincinnati, Cincinnati, OH, 1981.

    Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1981-1984.

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, OH 1984-1987 (Peter Dignan, Director).

    Certifications: National Board of Medical Examiners, 7/1982;  American Board of Pediatrics, 5/1986; American Board of Medical Genetics, 6/1987.

    Publications

    View PubMed Publications
    A photo of Kristin Melton, MD.

    Kristin R. Melton, MD Associate Program Director, Neonatal-Perinatal Medicine Fellowship

    is interested in early craniofacial development and focuses on the tissue interactions that direct the formation, migration and differentiation of neural crest cells. The Melton lab focuses on understanding the influence of the endothelium and the cranial mesoderm on neural crest development.

    513-803-0022

    Kristin R. Melton, MD

    Associate Program Director, Neonatal-Perinatal Medicine Fellowship

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-0022

    Fax: 513-636-7868

    Show All

    Specialties

    Clinical Interests

    Congenital malformations

    Research Interests

    Craniofacial malformations; somitogenesis

    Biography

    Craniofacial defects are an important cause of morbidity for children worldwide, with craniofacial defects making up one third of all congenital anomalies and occurring in association with over 100 different genetic syndromes. Cranial neural crest cells are multipotent, migratory cells that form most of the bone, cartilage, connective tissue and peripheral nervous system of the head and face. Craniofacial defects are largely attributed to abnormalities in the formation, migration or differentiation of the neural crest. The cranial neural crest is responsive to the tissues that surround it, however, so craniofacial defects may result from a primary defect in neural crest cells, or from a defect in the tissues that signal to neural crest.

    Kristin Melton, MD, has an interest in studying the tissues that signal to the neural crest, such as the endothelium and cranial mesoderm, and the signaling pathways utilized by these tissues. Using embryo culture techniques, cell culture and transgenic mouse models, Dr. Melton is investigating the interaction between the endothelium and the neural crest. Microarray has also been used to identify a number of mesoderm-specific genes that may play key roles in craniofacial development.

    Dr. Melton is a practicing neonatologist and attends at the RCNIC in Cincinnati Children’s Hospital. Her clinical interests include newborns with complex congenital anomalies and genetic defects, as well as a focus on family-centered care.

    Education and Training

    Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2001.

    Residency: Children's Mercy Hospital, Kansas City, Missouri, 1998.

    MD: University of Nebraska, Omaha, Nebraska, 1995.

    BA: Washington University, St. Louis, Missouri, 1991.

    Publications

    View PubMed Publications
    A photo of Stephanie Merhar.

    Stephanie L. Merhar, MD, MS Attending Neonatologist

    is interested in optimizing neuroimaging in preterm and term infants at risk for brain injury, neonatal seizure treatment and neurodevelopmental outcomes of infants in the NICU.

    513-803-5180
    stephanie.merhar@cchmc.org

    Stephanie L. Merhar, MD, MS

    Attending Neonatologist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-5180

    Email: stephanie.merhar@cchmc.org

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    Education and Training

    MD: University of Pennsylvania, Philadelphia, PA ,2005.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 2005-2008.

    Fellowship: Neonatology, Cincinnati Children's Hospital Medical Center, 2008-2011.

    Certification: Pediatrics, 2008.

    Publications

    View PubMed Publications
    A photo of Nagendra Monangi.

    Nagendra K. Monangi, MD Attending Neonatologist

    513-803-3982
    nagendra.monangi@cchmc.org

    Nagendra K. Monangi, MD

    Attending Neonatologist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-3982

    Email: nagendra.monangi@cchmc.org

    Show All

    Specialties

    Maternal / infant nutrition; vitamin D

    Education and Training

    MBBS: Andhra Medical College, Visakhapatnam, India, 2001.

    Post Graduate Diploma: Pediatrics, Osmania Medical College, Hyderabad, India, 2005.

    Residency: Pediatrics, University of South Alabama, Mobile, AL, 2009.

    Fellwoship: Neonatal-Perinatal Medicine, Cincinnati Children’s Hospital Medical Center / University of Cincinnati, Cincinnati, OH, 2012.

    Certification: Pediatrics, 2009; Neonatology, Board Eligible.

    A photo of Ardythe Morrow.

    Ardythe L. Morrow, PhD Director, Center for Interdisciplinary Research in Human Milk & Lactation

    513-636-7584
    ardythe.morrow@cchmc.org

    Ardythe L. Morrow, PhD

    Director, Center for Interdisciplinary Research in Human Milk & Lactation

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-7584

    Fax: 513-636-7509

    Email: ardythe.morrow@cchmc.org

    Show All

    Specialties

    Human milk; child health and nutrition

    Biography

    Dr. Morrow received her MSc in nutrition from the University of the West Indies, Kingston, Jamaica (1980) and PhD in epidemiology from the University of Texas at Houston (1991). Since 1987 she has worked with colleagues in Mexico, Boston, and Houston on an NIH-funded program project on human milk immune protection against infectious disease.

    She is currently Professor of Pediatrics at the University of Cincinnati College of Medicine and Cincinnati Children's Hospital Medical Center, where she founded and directs the Center for Epidemiology and Biostatistics that has 35 faculty and staff and a multi-disciplinary Human Milk Research Program that includes clinical and basic science investigators in eight divisions.

    She has published extensively on breastfeeding promotion and human milk protection against infectious diseases. Her primary focus is on protection by human milk glycans and protection against infectious disease, but she has expanded her research to understanding the relationship between breastfeeding and chronic diseases. She has been an ad hoc reviewer for NIH on breastfeeding research and a technical advisor for international breastfeeding policy and programs for Gates Foundation, UNICEF, and WHO, is on the editorial board of the Journal of Human Lactation and the journal of the Academy of Breastfeeding Medicine. She is an elected member of the American Pediatric Society. She has over 100 publications, and is the primary author of the WHO monograph, Community-based Strategies for Breastfeeding Promotion and Support in Developing Countries (2004).

    She has served as Chair of the Milk Club of the (American) Society for Pediatric Research for the past 4 years. In 1997, she received a Young Investigator award from ISRHML for her randomized trial of breastfeeding support (Lancet, 1999). She was co-organizer of the 2002 ISRHML international meeting in Mexico and is co-editor of the book Protecting Infants through Human Milk: Advancing the Scientific Evidence.

    Education and Training

    BA: Rice University, Houston, Texas.

    MSc: University of the West Indies, Kingston, Jamaica.

    PhD: The University of Texas School of Public Health, Houston, Texas 1991.

    Publications

    View PubMed Publications
    A photo of Laurel Moyer.

    Laurel B. Moyer, MD Medical Director, TriHealth Nurseries

    has research interests that include quality improvement, late preterm infants, and international health.

    513-803-1607
    laurel.moyer@cchmc.org

    Laurel B. Moyer, MD

    Medical Director, TriHealth Nurseries

    Chair, Neonatal Pediatrics

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-1607

    Fax: 513-803-0968

    Email: laurel.moyer@cchmc.org

    Show All

    Specialties

    Quality improvement; global health

    Education and Training

    MD: University of Vermont College of Medicine, Burlington, VT, 1999-2003.

    Residency: University of Massachusetts, Department of Pediatrics, Worcester, MA, 2003-2006.

    Fellowship: University of North Carolina, Division of Neonatal-Perinatal Medicine, Chapel Hill, NC, 2006-2009.

    Certification: American Board of Pediatrics, 2006.
    A photo of Vivek Narendran, MD.

    Vivek Narendran, MD, MRCP, MBA Medical Director, University of Cincinnati Medical Center NICU

    is interested in innate immunity of the skin with a particular focus on epidermal biomarkers and antimicrobial peptides on the skin surface.

    513-803-0961
    vivek.narendran@cchmc.org

    Vivek Narendran, MD, MRCP, MBA

    Medical Director, University of Cincinnati Medical Center NICU

    Medical Director, Cincinnati Perinatal Outreach Project

    Director, Neonatal Intensive Care Unit and Newborn Services, Christ Hospital

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-0961

    Fax: 513-803-0969

    Email: vivek.narendran@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Non-Invasive Ventilation of the Preterm Infant, Business Case for Quality Improvements

    Research Interests

    Interested in innate immunity of the skin with a particular focus on epidermal biomarkers and antimicrobial peptides on the skin surface

    Education and Training

    MBBS: Bangalore Medical College, Bangalore, India, 1985.

    MD/DNB: JN Medical College, Belgaum, India, 1990.

    Fellowship: Neonatology, Westmead Hospital, Sydney, Australia, 1992-94. 

    Residency: Pediatrics, Leicester Royal Infirmary, Leicester, United Kingdom, 1994-1996. 

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 1997-1998. 

    Fellowship: Neonatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 1996, 1998-2000. 

    Credentials: Pediatrics, 1998; Pediatrics, Royal College of Physicians (MRCP), United Kingdom, 1996; Neonatal-Perinatal Medicine 2001 & 2008.

    Publications

    View PubMed Publications
    A photo of Amy Nathan, MD.

    Amy T. Nathan, MD Medical Director, Neonatology

    focuses on antecedent factors leading to necrotizing enterocolitis, and is interested in applying quality improvement methods to reduce the incidence of this major morbidity in preterm infants.

    513-803-0909
    amy.nathan@cchmc.org

    Amy T. Nathan, MD

    Medical Director, Neonatology

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0909

    Email: amy.nathan@cchmc.org

    Show All

    Specialties

    Clinical Interests

    necrotizing enterocolitis; quality improvement; neonatal immune responses; family-centered care

    Research Interests

    Immune modulation of lung injury and inflammation 

    Biography

    Innate immune responses at the epithelial boundaries in preterm infants (lung, intestine) can be protective, but inflammatory responses may also cause significant damage. Necrotizing enterocolitis is a devastating, multi-factorial disease marked by intense inflammation, which may be related to changes in the intestinal microbiome combined with compromised perfusion. Dr. Nathan focuses on antecedent factors leading to necrotizing enterocolitis, and is interested in applying quality improvement methods to reduce the incidence of this major morbidity in preterm infants.

    Education and Training

    MD: Yale University School of Medicine, New Haven, CT, 1998.

    Residency: University of North Carolina, Chapel Hill, NC 1998-2002.

    Fellowship: University of North Carolina, Chapel Hill, NC 2002-2005.

    Certification: Pediatrics 2001; Neonatology, 2008 

    Publications

    View PubMed Publications
    A photo of Laurie Nommsen-Rivers.

    Laurie Nommsen-Rivers, PhD, RD, IBCLC

    has research interests that include human milk and lactation, clinical management of the breastfeeding dyad and perinatal epidemiology. 

    513-636-7208
    laurie.nommsen-rivers@cchmc.org

    Laurie Nommsen-Rivers, PhD, RD, IBCLC

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-7208

    Fax: 513-803-0968

    Email: laurie.nommsen-rivers@cchmc.org

    Show All

    Specialties

    Broad research objective is to provide evidence-based strategies for supporting the mother-baby dyad in successfully establishing breastfeeding; current area of research examines the causes and consequences of early breastfeeding difficulties, with particular emphasis on delayed onset of lactogenesis

    Biography

    Laurie Nommsen-Rivers, PhD, RD, IBCLC, worked with hundreds of breastfeeding dyads as a staff researcher in the field of human lactation before returning to school in 2004 to pursue a PhD in Epidemiology.  She has co-authored over 50 publications related to maternal child health.  In addition, Laurie Nommsen-Rivers served as the Associate Editor of the Journal of Human Lactation from 1997 to 2006.

    Education and Training

    PhD: University of California, Davis; December 2007.

    MS: University of California, Davis, September 1989.

    BS: University of California, Davis, 1985.

    Registered Dietitian: Registration # 706227, continuously since 1991.

    International Board Certified Lactation Consultant: Continuously since 1993 

    Publications

    View PubMed Publications
    A photo of Mihaela Pavlicev.

    Mihaela Pavlicev, PhD

    is an evolutionary geneticist working on the structure of genetic variation of complex traits, with a special focus on epistasis and pleiotropy. Understanding how past evolution shaped this structure can help identify the genetic basis of complex traits, including complex disease. The lab uses computational, theoretical and experimental methods in two systems: vertebrate limbs and birth timing.


    mihaela.pavlicev@cchmc.org

    Mihaela Pavlicev, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

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    Education and Training

    PhD: University of Vienna, Austria, 2003.

    Postdoc: Washington University St. Louis (with Jim Cheverud), University of Oslo (with Thomas Hansen).

    Publications

    View PubMed Publications
    A photo of John Reuter.

    John H. Reuter, MD, PhD Attending Neonatologist

    is active in the administration of a 4000 delivery/year community level II service. His academic interests include breast milk and nutrition in the preterm infant.

    513-862-2748
    john.reuter@cchmc.org

    John H. Reuter, MD, PhD

    Attending Neonatologist

    Chair, Department of Pediatrics at Bethesda North Hospital Nurseries

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-862-2748

    Fax: 513-862-4979

    Email: john.reuter@cchmc.org

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    Education and Training

    MD: University of Cincinnati College of Medicine, Cincinnati, Ohio, 1976.

    PhD:
    Physiology, University of Cincinnati College of Medicine, 1973.

    Residency: Pediatrics, University of Cincinnati and Children's Hospital Medical Center, Cincinnati, Ohio, 1978.

    Fellowship: Moffitt Hospital, Cardiovascular Research Institute, University of California at San Francisco, San Francisco, Calif., 1980.

    Certifications: Pediatrics, 1982 Neonatal; Perinatal Medicine, 1983.

    photo of Ward Rice, MD, PhD.

    Ward R. Rice, MD, PhD Medical Director, Newborn Services, St. Elizabeth Medical Center

    studies the molecular and cellular mechanisms that regulate processing of Surfactant Protein C, a protein that is critical for lung function.

    513-636-3149
    ward.rice@cchmc.org

    Ward R. Rice, MD, PhD

    Medical Director, Newborn Services, St. Elizabeth Medical Center

    Director, Neonatology Fellowship Training Program

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-3149

    Fax: 513-636-7868

    Email: ward.rice@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Hypotension in ELBW infants; EMR

    Research Interests

    Processing of Surfactant Protein C

    Biography

    Ward R. Rice, MD, PhD, is the Director of the Neonatology Fellowship Training Program and Director of Newborn Services, St. Elizabeth Medical Center.

    Dr. Rice received MD and PhD degrees from the University of Chicago and has been on the faculty since 1983. He has been the Director of the Neonatology Fellowship Training Program since 1990. During this time, he has supervised the clinical training of more than 100 fellows who currently hold academic appointments across the United States and around the world.

    His past NIH supported research accomplishments included identification of novel G-protein coupled receptors on alveolar type II cells and studies of the interaction of the opportunistic pathogen P carinii with alveolar type II cells. He currently works in collaboration with Dr. Timothy Weaver to study biosynthesis of Surfactant Protein C.

    Education and Training

    PhD: 1972-76 University of Chicago, Chicago, Illinois.

    PhD: Biochemistry, Thesis Advisor: T.L. Steck, MD, Thesis: "Pyruvate Flux Across The Isolated Human Erythrocyte Membrane"

    MD: 1972-78 University of Chicago, Chicago, Illinois.

    Internship: 1978-79 Duke University Medical Center, Durham, North Carolina.

    Residency: 1979-81 Duke University Medical Center, Durham, North Carolina.

    Fellowship Neonatology: 1981-83 University of Cincinnati College of Medicine, Children's Hospital Medical Center.

    Certification: Pediatrics, 1983; Sub-board Neonatal-Perinatal Medicine, 1983.

    Publications

    View PubMed Publications
    A photo of Kurt Schibler.

    Kurt R. Schibler, MD Director, Neonatology Clinical Research Program

    is the principal investigator for the NICHD Neonatal Research Network at Cincinnati Children’s and is also involved in thematic collaborative research investigating the immune mechanisms underlying morbidity and mortality associated with preterm birth. He aims to identify infants at high risk for developing necrotizing enterocolitis and late onset infection and to devise strategies to prevent and to treat these complications.

    513-636-3972
    kurt.schibler@cchmc.org

    Kurt R. Schibler, MD

    Director, Neonatology Clinical Research Program

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-3972

    Fax: 513-636-7868

    Email: kurt.schibler@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Clinical trials; neonatal immune development

    Research Interests

    Immune mechanisms underlying morbidity and mortality associated with preterm birth; necrotizing enterocolitis; complications of prematurity

    Education and Training

    MD: University of Cincinnati, Cincinnati, Ohio, 1984.

    Residency: Pediatrics, Indiana University, Indianapolis, Indiana, 1990.

    Fellowship: Neonatology, University of Utah, Salt Lake City, Utah, 1993.

    Certification: Pediatrics 1990; Neonatal-Perinatal Medicine 1993, renewed 1999 and 2007.

    Publications

    View PubMed Publications

    Grants

    The natural history of CMV-related hearing loss and the feasibility of CMV screening as adjunct to hearing in the newborn. Co-investigator. National Institutes of Health. Jan 2006 - Dec 2012. #HHS-N-260200500008C.

    Novel genetic and salivary glycan biomarkers for risk of NEC in ELBW infants. Co-Principal Investigator. National Institutes of Health. Mar 2009 - Feb 2014. #R01-HD059140.

    A photo of Deborah Sinner.

    Debora I. Sinner, PhD

    is interested in understanding the molecular mechanisms underlying foregut formation. Specifically, her lab focuses on the molecular mechanism underlying lung and upper airway development and the paracrine interactions between epithelium and mesenchyme. Ultimately, her goal is to use the embryo as a paradigm to understand diseases affecting upper airway and lung. To this end her lab utilizes knockout mouse models and the frog embryo combined with molecular and cellular approaches using in vitro systems.

    513-803-1353
    debora.sinner@cchmc.org

    Debora I. Sinner, PhD

    Academic Information

    Instructor, UC Department of Pediatrics

    Phone: 513-803-1353

    Email: debora.sinner@cchmc.org

    Show All

    Specialties

    Developmental biology; pulmonary biology

    Visit the Sinner Lab.

    Biography

    Debora Sinner, PhD, obtained her doctoral degree from University of Buenos Aires, Argentina. Her dissertation focused on the effects of maternal diabetes during murine embryonic development and role of prostaglandins and reactive species of oxygen in glucose induced abnormal development. As a postdoctoral trainee in the Division of Developmental Biology at Cincinnati Children's, Dr. Sinner focused on the molecular mechanisms underlying endoderm formation, the germ layer that gives rise to the gastrointestinal tract. Under the direction of her mentor, Aaron Zorn, PhD, we identified a mechanism by which Sox proteins regulate the Wnt signaling pathway during frog development. These findings are relevant since Wnt signaling pathway has been linked to development and disease.

    After completion of her doctoral training, Dr. Sinner accepted a faculty position in the Division of Neonatology and Pulmonary Biology. Her current research focuses on upper airway and lung development. Dr. Sinner's lab is studying how paracrine Wnt signaling controls the differentiation of pulmonary cells lineages, including the microvasculature and airway cartilage.

    Education and Training

    MS: University of Buenos Aires, Argentina, 1999.

    PhD: University of Buenos Aires, Argentina, 2003.

    Post doctoral training: Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2003-2009.

    Publications

    View PubMed Publications

    Grants

    "Molecular mechanisms underlying lung growth and hypoplasia: Role of Wntless" Basil O' Connor Starter Scholar Research Award. March of Dimes. 2/1/2012-1/30/2014

    "Molecular mechanisms underlying upper airway patterning and tracheomalacia" K01  NIH-NHLBI 8/1/2012-7/31/2017

    A photo of Laura Ward.

    Laura Placke Ward, MD

    focuses on strategies to prevent significant hyperbilirubinemia in term and late preterm infants.

    513-803-0963
    laura.ward@cchmc.org

    Laura Placke Ward, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-0963

    Fax: 513-803-0969

    Email: laura.ward@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Multidisciplinary quality improvement; family centered care; evidence-based practice

    Research Interests

    Strategies to prevent significant hyperbilirubinemia in infants

    Biography

    Dr. Ward has been a neonatologist in the division since 2002, and attends at The University Hospital.

    Education and Training

    MD: St. Louis University School of Medicine, St. Louis, Missouri, 1994.

    Residency: Children’s National Medical Center, Washington DC, 1994-1997.

    Fellowship: Children’s National Medical Center, Washington DC, 1997-2000.

    Certifications: Pediatrics, 1997; Neonatology, 2003.
    A photo of Kathy Wedig.

    Kathy E. Wedig-Stevie, MD Medical Director, High Risk Follow-up Clinic at Good Samaritan Hospital

    focuses on neonatal follow-up, including the follow-up of graduates from the NICU and drug exposed neonates with neonatal abstinence syndrome. Her future research plans involve neuroimaging and therapy based on the neurological findings.

    513-872-2748
    kathy.wedig@cchmc.org

    Kathy E. Wedig-Stevie, MD

    Medical Director, High Risk Follow-up Clinic at Good Samaritan Hospital

    Neonatologist, Good Samaritan Hospital

    Medical Director, Mercy Hospital Fairfield Nurseries

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-872-2748

    Fax: 513-872-4979

    Email: kathy.wedig@cchmc.org

    Show All

    Specialties

    Neonatal high risk infant follow-up and developmental follow-up

    Education and Training

    MD: University of Cincinnati Medical School, Cincinnati, Ohio, 1978.

    Residency:
    Pediatrics, University of Cincinnati Medical Center, Cincinnati, Ohio, 1978-1981.

    Fellowship: Neonatology, University Hospitals: Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio, 1983.

    Certifications: Pediatrics, 1983; Neonatology, 1983.

    Publications

    View PubMed Publications
    A photo of Scott Wexelblatt.

    Scott L. Wexelblatt, MD Medical Director, Regional Newborn Services

    has interests in the late preterm infant and regional newborn care.

    513-803-2681
    scott.wexelblatt@cchmc.org

    Scott L. Wexelblatt, MD

    Medical Director, Regional Newborn Services

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-2681

    Fax: 513-803-2633

    Email: scott.wexelblatt@cchmc.org

    Show All

    Education and Training

    MD: University of Vermont, Burlington, VT. 1996.

    Residency: Cincinnati Children’s Hospital Medical Center.

    Certification: Pediatrics, 1999.