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Nephrology and Hypertension
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Nephrology and Hypertension
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4:01:33 AM
Nephrology and Hypertension
Significant Accomplishments, 2011-12
Biomarker Lab
Research Faculty
Faculty Labs
Grants, 2011-12
Publications, 2011-12
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Division Publications
Abraham BP
,
Frazier EA
,
Morrow WR
,
Blaszak RT
,
Devarajan P
,
Mitsnefes M
,
Bryant JC
,
Sachdeva R
.
Cystatin C and neutrophil gelatinase-associated lipocalin as markers of renal function in pediatric heart transplant recipients
.
Pediatr Transplant
.
2011
;
15
:
564-9
.
Arikan AA
,
Zappitelli M
,
Goldstein SL
,
Naipaul A
,
Jefferson LS
,
Loftis LL
.
Fluid overload is associated with impaired oxygenation and morbidity in critically ill children
.
Pediatr Crit Care Med
.
2012
;
13
:
253-8
.
Askenazi DJ
,
Goldstein SL
.
Renal Conditions
.
Manual of Neonatal Care
.
Philadephia
:
Lippincott Williams & Wilkins
;
2011
:
350-376
.
Askenazi DJ
,
Koralkar R
,
Levitan EB
,
Goldstein SL
,
Devarajan P
,
Khandrika S
,
Mehta RL
,
Ambalavanan N
.
Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants
.
Pediatr Res
.
2011
;
70
:
302-6
.
Askenazi DJ
,
Montesanti A
,
Hunley H
,
Koralkar R
,
Pawar P
,
Shuaib F
,
Liwo A
,
Devarajan P
,
Ambalavanan N
.
Urine biomarkers predict acute kidney injury and mortality in very low birth weight infants
.
J Pediatr
.
2011
;
159
:
907-12 e1
.
Bagshaw SM
,
Haase M
,
Haase-Fielitz A
,
Bennett M
,
Devarajan P
,
Bellomo R
.
A prospective evaluation of urine microscopy in septic and non-septic acute kidney injury
.
Nephrol Dial Transplant
.
2012
;
27
:
582-8
.
Basu RK
,
Donaworth E
,
Wheeler DS
,
Devarajan P
,
Wong HR
.
Antecedent acute kidney injury worsens subsequent endotoxin-induced lung inflammation in a two-hit mouse model
.
Am J Physiol Renal Physiol
.
2011
;
301
:
F597-604
.
Basu RK
,
Standage SW
,
Cvijanovich NZ
,
Allen GL
,
Thomas NJ
,
Freishtat RJ
,
Anas N
,
Meyer K
,
Checchia PA
,
Lin R
,
Shanley TP
,
Bigham MT
,
Wheeler DS
,
Devarajan P
,
Goldstein SL
,
Wong HR
.
Identification of candidate serum biomarkers for severe septic shock-associated kidney injury via microarray
.
Crit Care
.
2011
;
15
:
R273
.
Bennett MR
,
Piyaphanee N
,
Czech K
,
Mitsnefes M
,
Devarajan P
.
NGAL distinguishes steroid sensitivity in idiopathic nephrotic syndrome
.
Pediatr Nephrol
.
2012
;
27
:
807-12
.
Bissler JJ
.
Polycystic Kidney Disease
.
Clinician's Manual of Pediatric Nephrology
.
Singapore; Hackensack, NJ
:
World Scientific Publishing Co
;
2011
:
703-712
.
Blinder JJ
,
Goldstein SL
,
Lee VV
,
Baycroft A
,
Fraser CD
,
Nelson D
,
Jefferies JL
.
Congenital heart surgery in infants: effects of acute kidney injury on outcomes
.
J Thorac Cardiovasc Surg
.
2012
;
143
:
368-74
.
Cavanaugh TM
,
Schoenemen H
,
Goebel J
.
The impact of sirolimus on sex hormones in male adolescent kidney recipients
.
Pediatr Transplant
.
2012
;
16
:
280-5
.
Coca SG
,
Jammalamadaka D
,
Sint K
,
Thiessen Philbrook H
,
Shlipak MG
,
Zappitelli M
,
Devarajan P
,
Hashim S
,
Garg AX
,
Parikh CR
.
Preoperative proteinuria predicts acute kidney injury in patients undergoing cardiac surgery
.
J Thorac Cardiovasc Surg
.
2012
;
143
:
495-502
.
Czech KA
,
Bennett M
,
Devarajan P
.
Distinct metalloproteinase excretion patterns in focal segmental glomerulosclerosis
.
Pediatr Nephrol
.
2011
;
26
:
2179-84
.
Devarajan P
.
Acute Kidney Injury
.
Pediatric Nephrology: A Handbook for Training Health Care Providers
.
Singapore; Hackensack, NJ
:
World Scientific Publishing Co
;
2011
:
159-194
.
Devarajan P
.
Acute Kidney Injury (AKI)
.
Clinician's Manual of Pediatric Nephrology
.
Singapore; Hackensack, NJ
:
World Scientific Publishing Company
;
2011
:
437-464
.
Faubel S
,
Chawla LS
,
Chertow GM
,
Goldstein SL
,
Jaber BL
,
Liu KD
.
Ongoing clinical trials in AKI
.
Clin J Am Soc Nephrol
.
2012
;
7
:
861-73
.
Flynn JT
,
Pierce CB
,
Miller ER, 3rd
,
Charleston J
,
Samuels JA
,
Kupferman J
,
Furth SL
,
Warady BA
.
Reliability of resting blood pressure measurement and classification using an oscillometric device in children with chronic kidney disease
.
J Pediatr
.
2012
;
160
:
434-440 e1
.
Goebel J
,
DeFoor WR
,
Sheldon CA
.
Pediatric Kidney Transplantation
.
Clinician's Manual of Pediatric Nephrology
.
Singapore; Hackensack, NJ
:
World ScientificPublishing Co.
;
2011
:
583-601
.
Goebel J
,
Pai A
.
Creating a monster: non-adherence underlying late transplant rejection
.
Pediatr Transplant
.
2012
;
16
:
312-4
.
Goldstein SL
.
Acute kidney injury in children and its potential consequences in adulthood
.
Blood Purif
.
2012
;
33
:
131-7
.
Goldstein SL
.
Therapeutic apheresis in children: special considerations
.
Semin Dial
.
2012
;
25
:
165-70
.
Goldstein SL
.
Acute kidney injury biomarkers: renal angina and the need for a renal troponin I
.
BMC Med
.
2011
;
9
:
135
.
Goldstein SL
.
Acute kidney injury in children: prevention, treatment and rehabilitation
.
Contrib Nephrol
.
2011
;
174
:
163-72
.
Goldstein SL
.
A novel use for novel acute kidney injury biomarkers: fenoldopam's effect on neutrophil gelatinase-associated lipocalin and cystatin C
.
Crit Care
.
2011
;
15
:
177
.
Goldstein SL
,
Klaus G
,
Friedman DF
,
Kim HC
.
Pediatric Therapeutic Apheresis
.
Pediatric Dialysis
.
New York
:
Springer
;
2011
:
775-796
.
Goldstein SL
,
Klaus G
,
Friedman DF
,
Kim HC
.
Prescribing and Monitoring Hemodialysis
.
Pediatric Dialysis
.
New York
:
Springer
;
2011
:
313-320
.
Haines HL
,
Laskin BL
,
Goebel J
,
Davies SM
,
Yin HJ
,
Lawrence J
,
Mehta PA
,
Bleesing JJ
,
Filipovich AH
,
Marsh RA
,
Jodele S
.
Blood, and not urine, BK viral load predicts renal outcome in children with hemorrhagic cystitis following hematopoietic stem cell transplantation
.
Biol Blood Marrow Transplant
.
2011
;
17
:
1512-9
.
Hooper DK
,
Fukuda T
,
Gardiner R
,
Logan B
,
Roy-Chaudhury A
,
Kirby CL
,
Vinks AA
,
Goebel J
.
Risk of tacrolimus toxicity in CYP3A5 nonexpressors treated with intravenous nicardipine after kidney transplantation
.
Transplantation
.
2012
;
93
:
806-12
.
Iyngkaran P
,
Schneider H
,
Devarajan P
,
Anavekar N
,
Krum H
,
Ronco C
.
Cardio-renal syndrome: new perspective in diagnostics
.
Semin Nephrol
.
2012
;
32
:
3-17
.
Jodele S
,
Bleesing JJ
,
Mehta PA
,
Filipovich AH
,
Laskin BL
,
Goebel J
,
Pinkard SL
,
Davies SM
.
Successful early intervention for hyperacute transplant-associated thrombotic microangiopathy following pediatric hematopoietic stem cell transplantation
.
Pediatr Transplant
.
2012
;
16
:
E39-42
.
Kavanaugh GM
,
Wise-Draper TM
,
Morreale RJ
,
Morrison MA
,
Gole B
,
Schwemberger S
,
Tichy ED
,
Lu L
,
Babcock GF
,
Wells JM
,
Drissi R
,
Bissler JJ
,
Stambrook PJ
,
Andreassen PR
,
Wiesmuller L
,
Wells SI
.
The human DEK oncogene regulates DNA damage response signaling and repair
.
Nucleic Acids Res
.
2011
;
39
:
7465-76
.
Krawczeski CD
,
Goldstein SL
,
Woo JG
,
Wang Y
,
Piyaphanee N
,
Ma Q
,
Bennett M
,
Devarajan P
.
Temporal relationship and predictive value of urinary acute kidney injury biomarkers after pediatric cardiopulmonary bypass
.
J Am Coll Cardiol
.
2011
;
58
:
2301-9
.
Kwiatkowski DM
,
Goldstein SL
,
Krawczeski CD
.
Biomarkers of acute kidney injury in pediatric cardiac patients
.
Biomark Med
.
2012
;
6
:
273-82
.
Laskin BL
,
Goebel J
,
Davies SM
,
Jodele S
.
Small vessels, big trouble in the kidneys and beyond: hematopoietic stem cell transplantation-associated thrombotic microangiopathy
.
Blood
.
2011
;
118
:
1452-62
.
Lo MM
,
Salisbury S
,
Scherer PE
,
Furth SL
,
Warady BA
,
Mitsnefes MM
.
Serum adiponectin complexes and cardiovascular risk in children with chronic kidney disease
.
Pediatr Nephrol
.
2011
;
26
:
2009-17
.
Malatesta-Muncher R
,
Mitsnefes MM
.
Management of blood pressure in children
.
Curr Opin Nephrol Hypertens
.
2012
;
21
:
318-22
.
Mian AI
,
Du Y
,
Garg HK
,
Caviness AC
,
Goldstein SL
,
Bryan NS
.
Urinary nitrate might be an early biomarker for pediatric acute kidney injury in the emergency department
.
Pediatr Res
.
2011
;
70
:
203-7
.
Mitsnefes MM
.
Cardiovascular disease in children with chronic kidney disease
.
J Am Soc Nephrol
.
2012
;
23
:
578-85
.
Moffett BS
,
Goldstein SL
,
Adusei M
,
Kuzin J
,
Mohan P
,
Mott AR
.
Risk factors for postoperative acute kidney injury in pediatric cardiac surgery patients receiving angiotensin-converting enzyme inhibitors
.
Pediatr Crit Care Med
.
2011
;
12
:
555-9
.
Molitoris BA
,
Okusa MD
,
Palevsky PM
,
Chawla LS
,
Kaufman JS
,
Devarajan P
,
Toto RM
,
Hsu CY
,
Greene TH
,
Faubel SG
,
Kellum JA
,
Wald R
,
Chertow GM
,
Levin A
,
Waikar SS
,
Murray PT
,
Parikh CR
,
Shaw AD
,
Go AS
,
Chinchilli VM
,
Liu KD
,
Cheung AK
,
Weisbord SD
,
Mehta RL
,
Stokes JB
,
Thompson AM
,
Thompson BT
,
Westenfelder CS
,
Tumlin JA
,
Warnock DG
,
Shah SV
,
Xie Y
,
Duggan EG
,
Kimmel PL
,
Star RA
.
Design of clinical trials in AKI: a report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings
.
Clin J Am Soc Nephrol
.
2012
;
7
:
856-60
.
Muller D
,
Goldstein SL
.
Hemodialysis in children with end-stage renal disease
.
Nat Rev Nephrol
.
2011
;
7
:
650-8
.
Nehus E
,
Goebel J
,
Mitsnefes M
,
Lorts A
,
Laskin B
.
Intensive hemodialysis for cardiomyopathy associated with end-stage renal disease
.
Pediatr Nephrol
.
2011
;
26
:
1909-12
.
Nehus EJ
,
Devarajan P
.
Acute kidney injury: AKI in kidney transplant recipients--here to stay
.
Nat Rev Nephrol
.
2012
;
8
:
198-9
.
Nejat M
,
Pickering JW
,
Devarajan P
,
Bonventre JV
,
Edelstein CL
,
Walker RJ
,
Endre ZH
.
Some biomarkers of acute kidney injury are increased in pre-renal acute injury
.
Kidney Int
.
2012
;
81
:
1254-62
.
Nickolas TL
,
Schmidt-Ott KM
,
Canetta P
,
Forster C
,
Singer E
,
Sise M
,
Elger A
,
Maarouf O
,
Sola-Del Valle DA
,
O'Rourke M
,
Sherman E
,
Lee P
,
Geara A
,
Imus P
,
Guddati A
,
Polland A
,
Rahman W
,
Elitok S
,
Malik N
,
Giglio J
,
El-Sayegh S
,
Devarajan P
,
Hebbar S
,
Saggi SJ
,
Hahn B
,
Kettritz R
,
Luft FC
,
Barasch J
.
Diagnostic and prognostic stratification in the emergency department using urinary biomarkers of nephron damage: a multicenter prospective cohort study
.
J Am Coll Cardiol
.
2012
;
59
:
246-55
.
Okusa MD
,
Molitoris BA
,
Palevsky PM
,
Chinchilli VM
,
Liu KD
,
Cheung AK
,
Weisbord SD
,
Faubel S
,
Kellum JA
,
Wald R
,
Chertow GM
,
Levin A
,
Waikar SS
,
Murray PT
,
Parikh CR
,
Shaw AD
,
Go AS
,
Chawla LS
,
Kaufman JS
,
Devarajan P
,
Toto RM
,
Hsu CY
,
Greene TH
,
Mehta RL
,
Stokes JB
,
Thompson AM
,
Thompson BT
,
Westenfelder CS
,
Tumlin JA
,
Warnock DG
,
Shah SV
,
Xie Y
,
Duggan EG
,
Kimmel PL
,
Star RA
.
Design of clinical trials in acute kidney injury: a report from an NIDDK workshop--prevention trials
.
Clin J Am Soc Nephrol
.
2012
;
7
:
851-5
.
Pai AL
,
Rausch J
,
Tackett A
,
Marsolo K
,
Drotar D
,
Goebel J
.
System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation
.
Pediatr Transplant
.
2012
;
16
:
329-34
.
Pai AL
,
Tackett A
,
Ittenbach RF
,
Goebel J
.
Psychosocial Assessment Tool 2.0_General: validity of a psychosocial risk screener in a pediatric kidney transplant sample
.
Pediatr Transplant
.
2012
;
16
:
92-8
.
Palevsky PM
,
Molitoris BA
,
Okusa MD
,
Levin A
,
Waikar SS
,
Wald R
,
Chertow GM
,
Murray PT
,
Parikh CR
,
Shaw AD
,
Go AS
,
Faubel SG
,
Kellum JA
,
Chinchilli VM
,
Liu KD
,
Cheung AK
,
Weisbord SD
,
Chawla LS
,
Kaufman JS
,
Devarajan P
,
Toto RM
,
Hsu CY
,
Greene T
,
Mehta RL
,
Stokes JB
,
Thompson AM
,
Thompson BT
,
Westenfelder CS
,
Tumlin JA
,
Warnock DG
,
Shah SV
,
Xie Y
,
Duggan EG
,
Kimmel PL
,
Star RA
.
Design of clinical trials in acute kidney injury: report from an NIDDK workshop on trial methodology
.
Clin J Am Soc Nephrol
.
2012
;
7
:
844-50
.
Parikh CR
,
Coca SG
,
Thiessen-Philbrook H
,
Shlipak MG
,
Koyner JL
,
Wang Z
,
Edelstein CL
,
Devarajan P
,
Patel UD
,
Zappitelli M
,
Krawczeski CD
,
Passik CS
,
Swaminathan M
,
Garg AX
.
Postoperative biomarkers predict acute kidney injury and poor outcomes after adult cardiac surgery
.
J Am Soc Nephrol
.
2011
;
22
:
1748-57
.
Parikh CR
,
Devarajan P
,
Zappitelli M
,
Sint K
,
Thiessen-Philbrook H
,
Li S
,
Kim RW
,
Koyner JL
,
Coca SG
,
Edelstein CL
,
Shlipak MG
,
Garg AX
,
Krawczeski CD
.
Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery
.
J Am Soc Nephrol
.
2011
;
22
:
1737-47
.
Prowle JR
,
Calzavacca P
,
Licari E
,
Ligabo EV
,
Echeverri JE
,
Haase M
,
Haase-Fielitz A
,
Bagshaw SM
,
Devarajan P
,
Bellomo R
.
Pilot double-blind, randomized controlled trial of short-term atorvastatin for prevention of acute kidney injury after cardiac surgery
.
Nephrology (Carlton)
.
2012
;
17
:
215-24
.
Ralib AM
,
Pickering JW
,
Shaw GM
,
Devarajan P
,
Edelstein CL
,
Bonventre JV
,
Endre ZH
.
Test characteristics of urinary biomarkers depend on quantitation method in acute kidney injury
.
J Am Soc Nephrol
.
2012
;
23
:
322-33
.
Romick-Rosendale LE
,
Brunner HI
,
Bennett MR
,
Mina R
,
Nelson S
,
Petri M
,
Kiani A
,
Devarajan P
,
Kennedy MA
.
Identification of urinary metabolites that distinguish membranous lupus nephritis from proliferative lupus nephritis and focal segmental glomerulosclerosis
.
Arthritis Res Ther
.
2011
;
13
:
R199
.
Saldana SN
,
Hooper DK
,
Froehlich TE
,
Campbell KM
,
Prows CA
,
Sadhasivam S
,
Nick TG
,
Seid M
,
Vinks AA
,
Glauser TA
.
Characteristics of successful recruitment in prospective pediatric pharmacogenetic studies
.
Clin Ther
.
2011
;
33
:
2072-81
.
Schroff R
,
Wuhl E
,
Mitsnefes M
.
The Cardiovascular Status of Pediatric Dialysis Patients
.
Pediatric Dialysis
.
New York
:
Springer
;
2011
:
505-530
.
Shaw AD
,
Bagshaw SM
,
Goldstein SL
,
Scherer LA
,
Duan M
,
Schermer CR
,
Kellum JA
.
Major complications, mortality, and resource utilization after open abdominal surgery: 0.9% saline compared to Plasma-Lyte
.
Ann Surg
.
2012
;
255
:
821-9
.
Shlipak MG
,
Coca SG
,
Wang Z
,
Devarajan P
,
Koyner JL
,
Patel UD
,
Thiessen-Philbrook H
,
Garg AX
,
Parikh CR
.
Presurgical serum cystatin C and risk of acute kidney injury after cardiac surgery
.
Am J Kidney Dis
.
2011
;
58
:
366-73
.
Shroff R
,
Weaver DJ, Jr.
,
Mitsnefes MM
.
Cardiovascular complications in children with chronic kidney disease
.
Nat Rev Nephrol
.
2011
;
7
:
642-9
.
Silverstein DM
,
Srivaths PR
,
Mattison P
,
Upadhyay K
,
Midgley L
,
Moudgil A
,
Goldstein SL
,
Feig DI
.
Serum uric acid is associated with high blood pressure in pediatric hemodialysis patients
.
Pediatr Nephrol
.
2011
;
26
:
1123-8
.
Singh S
,
Kline-Fath B
,
Bierbrauer K
,
Racadio JM
,
Salisbury S
,
Macaluso M
,
Jackson EC
,
Egelhoff JC
.
Comparison of standard, prone and cine MRI in the evaluation of tethered cord
.
Pediatr Radiol
.
2012
;
42
:
685-91
.
Siroky BJ
,
Bissler JJ
.
Stressed podocytes fail to fold: a potential new role of ER in FSGS
.
Am J Physiol Renal Physiol
.
2011
;
301
:
F494-5
.
Strife CF
.
Proteinuria
.
Clinician's Manual of Pediatric Nephrology
.
Singapore; Hackensack, NJ
:
World Scientific Publishing Co.
;
2011
:
163-172
.
Sundaram N
,
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