Significant Accomplishments

Comprehensive Neuromuscular program

Our Comprehensive Neuromuscular Care Center continues to be a center of excellence for the coordinated care of patients with pediatric neuromuscular disorders, especially Duchenne muscular dystrophy (DMD). More than 80 percent of our DMD patients travel here from other states and nations, including some from as far as Russia and Ireland.  We also have become world-class experts in caring for patients with dystrophinopathy. Meanwhile, our new “one stop” interdisciplinary neuromuscular clinic brings specialists from as many as nine different fields to one location to serve our patients with multi-system needs.

Our Research in Neuromuscular Disease

We participate in ongoing industry-sponsored clinical trials as well as in a transcriptomics and proteomics study in DMD. This has been attained through training of residents and fellows and collaboration with multiple divisions, including endocrinology, cardiology and radiology.

Breakthrough Headache Research

Our Headache Center, formed 16 years ago, continues to grow in the management, treatment and understanding of headaches in children, adolescents and young adults. Our multidisciplinary outpatient clinic, acute treatment center, young adult headache program and a focused inpatient service provide the basis for the research and educational activities, including an UCNS-certified Headache Medicine fellowship. Our research highlights from the past year include an NIH-sponsored study that demonstrated significant effectiveness of cognitive behavioral therapy in a multidisciplinary care model of the treatment of chronic migraine that is comparable to pharmaceutical treatment in adults. We also are comparing the effectiveness of amitriptyline and topiramate in the prevention of pediatric and adolescent migraine (CHAMP) study with significant collaborative effort from Behavioral Medicine and Clinical Psychology, the Center for Clinical and Translation Research and the Department of Biostatistics and Clinical Trials Statistical and Data Management Center at the University of Iowa.

Tuberous Sclerosis Program is the World’s Largest

Our Tuberous Sclerosis Program, now designated a Center of Excellence, is the largest in the world and the only one that manages every aspect of the disorder in both adults and children. We receive increasing numbers of national and international referrals because our program conducts leading-edge research while offering unique social and emotional support to patients and families, such as our TSC summer camp, the first and only one of its kind. Research conducted or led by our physicians has resulted in 15 peer-reviewed publications over the past year.  We also have launched an NIH-sponsored, multisite, national study to continue to improve care for children with TSC.