Gilbert-Wu Lab

  • Current Projects

      
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    + Repetitive Transcranial Magnetic Stimulation to Reduce Tics

    This study is a clinical trial funded by the Tourette Syndrome Association USA.  The protocol uses repetitive transcranial magnetic stimulation to treat patients with moderate - severe tic disorder/Tourette Syndrome.  This study is registered with ClinicalTrials.gov (http://clinicaltrials.gov/ct2/show/NCT01258790?term=wu+tourette&rank=1).

    Funding Source: Tourette Syndrome Association USA

     

    + Anomalous Motor Physiology in ADHD

    This NIH-funded study assesses and compares motor skill development in children ages 8 to 12 years old with ADHD as well as typically developing children. We are using transcranial magnetic stimulation (TMS) to identify abnormalities in brain excitability that correlate with ADHD symptoms.

    Funding: National Institutes of Health R01 MH078160

    Collaborator: Stewart Mostofsky, MDLaboratory for Neurocognitive and Imaging Research, Baltimore

     

    + Cortical Excitability: Phenotype and Biomarker in ADHD Therapy

    This NIH-funded study is evaluating motor cortex changes related to treatment with atomoxetine for ADHD symptoms in children. We are using TMS to study the brain before treatment and after one month of treatment with atomoxetine.

    Funding: NIH R01 MH08185

    Collaborator: Randy Sallee, MD, PhD, University of Cincinnati

     

    + Neuroplasticity in Tourette Syndrome

    This study is funded by the Tourette Syndrome Association USA and evaluates a long-term potentiation-like property in children and adults with Tourette syndrome. We are using a new TMS technique to study brain changes related to learning in the motor system in children and adults with Tourette syndrome as well as healthy children and adults.

    Funding: Tourette Syndrome Association USA

     

    + The Effect of Repetitive Transcranial Magnetic Stimulation on Post-Stroke Aphasia Recovery

    This innovative study uses low-intensity TMS to try to improve speech in patients who have lost speech function due to strokes.

    Funding: NINDS: R01NS048281

    Principle Investigator: Jerzy Szaflarski, MD, PhD, University of Cincinnati Neuroscience Institute

     

    + Neuroplasticity and Learning in Neurofibromatosis

    This study aims to measure and quantify abnormalities in the surface of the brain that may correspond to learning and behavioral problems that sometimes occur in children with neurofibromatosis type 1 (NF1).

     Funding: Cincinnati Children’s Hospital Medical Center pilot grant

     

    + Treatment of Obsessive Compulsive Disorder with Repetitive Transcranial Magnetic Stimulation

     This study uses localized TMS pulses to try to reduce anxiety in adolescents with obsessive compulsive disorder.

    Lead investigator:  Elana Harris, MD, PhD, Division of Child Psychiatry, Cincinnati Children’s