Gilbert / Wu Lab Research
Transcranial Magnetic Stimulation Unit
The Transcranial Magnetic Stimulation (TMS) Lab at Cincinnati Children’s is one of the first labs in the country to use TMS technology to study child and adolescent brain function. Our research explores a range of topics related to learning, brain development and coordination of movement.
TMS research involves using a hand-sized magnet to temporarily activate or inhibit areas on the surface of the brain. This allows us to measure and study the “excitability” of the brain’s circuits for controlling movements and behaviors.
The brain’s control of movement, speech and behavior involves a balance of both excitatory “GO” and inhibitory “STOP” signaling. We have been studying these signals in children and adults with Tourette syndrome and ADHD to learn more about brain development, control and coordination of movement, and disruptive symptoms and behaviors.
In addition, TMS allows us to study how the brain learns new skills. Learning new skills and behaviors involves strengthening some brain connections and weakening others, creating new brain signaling patterns. Called “neuroplasticity,” this adaptation may be important for understanding diseases and recovery.
We are also exploring the use of TMS to treat brain diseases. TMS can be used to externally apply energy to the brain and may mimic, or enhance, effects of therapy or practice. TMS pulses may also be able to modify abnormal brain activity linked to some diseases. We are exploring the use of TMS to precisely target areas of abnormal brain activity.
Contact Us
For more information about the TMS unit, contact our research assistant, David Huddleston, BA, at: david.huddleston@cchmc.org.
