(All fields required)
Please enter a valid email.
Please enter your name.
What is : (So we know you are human.)
Please supply the correct answer.
The fundamental features of locomotor behavior are controlled by neurons located in the spinal cord. Following spinal cord injury, spinal circuits are largely intact but lack key instructions from the brain.
Our hypothesis is that motor function could be restored following spinal cord injury by re-activating the spinal circuits that no longer receive a sufficient signal from the brain. We have discovered that V2a neurons are important for initiating locomotion in response to supraspinal and sensory input.
We are developing tools to activate motor circuits in animal models of spinal cord injury with the goal of devising novel treatment strategies to restore motor function (walking and breathing) to spinal cord injury patients.
Click image to enlarge and view caption.
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026 | 1-513-636-4200 | 1-800-344-2462 | TTY: 1-513-636-4900
New to Cincinnati Children’s or live outside of the Tristate area? 1-877-881-8479
© 1999-2015 Cincinnati Children's Hospital Medical Center