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Allie graduated with her Bachelor of Science in molecular genetics from The Ohio State University in 2009. She is now a PhD candidate in the Cancer and Cell Biology Program at the University of Cincinnati and joined the Wells Lab in 2010. Her project focuses on identifying transcriptional and functional consequences of DEK loss in head and neck cancer.
IHC depicting DEK positive primary human head and neck cancer.
Tim is a post-doctoral fellow who joined the Wells lab in 2012 after completing his PhD in Molecular Biology at Northwestern University in Chicago. He is originally from Louisville, KY and earned his BS in biological sciences from the University of Notre Dame in 2007. Tim's current research project is to develop human pluripotent stem cell models of Fanconi anemia.
These cells will be used to study the myriad of developmental abnormalities that affect FA patients.
Anne is a clinical fellow in pediatric hematology/oncology. She obtained her MD from UNC-Chapel Hill School of Medicine in 2008 and has been performing research with the Wells lab since 2012. Her main research focus is squamous cell carcinoma formation in Fanconi anemia patients and investigating the mechanisms by which cancer cells become resistant to chemotherapy so that more effective agents can be identified and developed.
Beth obtained her BS degree in biology from the University of Indianapolis in 2001 and her MS degree in neuroscience from Miami University in 2004 and joined the Wells Lab as a research assistant and laboratory manager soon after. Her focus of research in the lab is on the role of the Fanconi anemia DNA damage repair pathway in head and neck cancer.
Logan is an undergraduate student at the University of Cincinnati majoring in Neuroscience. He joined the Wells Lab in 2013 in the position of laboratory aide, where his work supports both the studies of DEK and Fanconi anemia.
Marie is a cancer and cell biology graduate student and joined the Wells Lab in 2011. Her focus of study is the DEK oncogene and its involvement in head and neck cancer and cancer cell metabolism.
Nick graduated from Xavier University with a BS in biology and joined the Wells Lab in 2013. He is an RA II focused on assisting Dr. Privette Vinnedge’s research concerning the role of DEK in breast cancer metastasis and chemotherapeutic resistance.
Lisa is a research instructor studying the role of DEK in breast cancer progression, with emphasis on Wnt signaling and breast cancer stem cells. She obtained a BA at Miami University (OH) with a double major in microbiology and classical humanities. She completed her MS and PhD degrees in human genetics at the University of Michigan before joining the Wells Lab in 2008 as a post-doctoral research fellow.
3-dimensional cell culture of immortalized human mammary epithelial cells. The addition of DEK (bottom) causes phenotypic changes similar to early events in breast cancer development.
Lindsey graduated with a BS in chemistry from Marietta College in 2007 and a PhD in chemistry from Miami University in 2011. She then became a postdoctoral fellow in the Wells Lab in January 2012. Lindsey studies the Fanconi anemia pathway and more specifically the role that inactivation of this DNA repair pathway plays in the development and progression of head and neck squamous cell carcinoma. Human, mouse and chick models are utilized.
Eric is an MD/PhD student pursuing his graduate training through the Cancer and Cell Biology program. He graduated from Rose-Hulman Institute of Technology with a BS in chemistry and biochemistry and molecular biology. Eric joined the Wells Lab after completing his second year of medical school. Eric studies the role of the DEK oncogene in DNA damage repair and is developing novel DEK-targeting approaches to enhance chemotherapy efficacy in head and neck carcinomas.
Click to enlarge.
We welcome interested students and postdocs to join us in our research. For more information, please contact us.
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