Ophthalmology

  • Research Faculty

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    Division Director

    A photo of Richard Lang.

    Richard A. Lang, PhD Director of the Visual Systems Group

    has two major research interests. First, we are interested in mechanisms of signaling and morphogenesis in early eye development. Second, we investigate the role macrophages play in regulating vascularity during development and homeostasis.
    Visit the Lang Lab.

    513-636-2700
    richard.lang@cchmc.org

    Richard A. Lang, PhD

    Director of the Visual Systems Group

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-2700

    Fax: 513-803-0740

    Email: richard.lang@cchmc.org

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    Specialties

    Wnt Ligands in Tumorigenesis; Vascular Regression and Tissue Regeneration; Lens Induction and Morphogenesis 

    Visit the Lang Lab.

    Education and Training

    BSc: 1984 (with honors), University of Melbourne, Australia. Co-major in genetics and biochemistry.

    PhD: 1988, University of Melbourne, Australia, at the Ludwig Institute for Cancer Research under Drs. AR Dunn and TJ Gonda.

    Postdoctoral Fellow: 1989-92, The G.W. Hooper Research Foundation, University of California, San Francisco under Dr. JM Bishop. Studied the role of the macrophage in developmentally programmed tissue remodeling.

    Publications

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    Grants

    Rho GTPases in early eye development. National Institute of Health. Apr 2007- Mar 2012. #R01 EY017848. 

    Macrophage and tumor angiogenesis. Co-Principal Investigator. National Institute of Health. Dec 2007- Nov 2012. #R01 CA131270.

    Targeting Survival Factors for Ocular Neovascularization. National Institute of Health. Apr 2008- Mar 2012. #R01 EY012609.

    CRIM1-β-catenin-Cadherin interactions in Eye Development and Disease. MPI with Dr. Rashmi Hegde of Cincinnati Children’s Hospital Medical Center. National Institute of Health. Apr 2009- Mar 2014. #R01 EY019377.

    Sox2 and Pax6 in Eye development. Co-Principal Investigator. US-Israel Binational Science Foundation.  
    Feb 2009- Jan 2013. 

    Eyes absent phosphatase inhibitors in eye disease. MPI with Dr. Rashmi Hegde of Cincinnati Children’s Hospital Medical Center. National Institute of Health. Apr 2009- Mar 2014. #R21 EY019125.

    Faculty

    A photo of Zubair Ahmed.

    Zubair M. Ahmed, PhD

    is working to identify and characterize genes that control the function of the visual and auditory sense organs of mammals through the study of individuals with genetic disorders like Usher syndrome (USH). His lab uses molecular biologic and genetic approaches, human and mouse models, as well as heterologous cell culture expression systems.
    View the Ahmed Lab.

    513-636-4718
    zubair.ahmed@cchmc.org

    Zubair M. Ahmed, PhD

    Academic Information

    Associate Professor, UC Department of Ophthalmology

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4718

    Fax: 513-803-0740

    Email: zubair.ahmed@cchmc.org

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    Specialties

    Education and Training

    Research fellow: Laboratory of Molecular Genetics, NIDCD, NIH, Rockville, MD, 2003-2009.

    Postdoctoral fellow: Laboratory of Molecular Genetics, NIDCD, NIH, Rockville, MD, 2002-2003.

    Pre-doctoral fellow: Laboratory of Molecular Genetics, National institute of Deafness and Other Communication Disorders (NIDCD), National Institutes of Health (NIH), Rockville, MD, 2000-2002.

    Publications

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    Grants

    Molecular Genetics of Usher Syndrome Type I. National Institutes of Health. Aug 2009- Jul 2012. #1K99DC009287.
    A photo of Tiffany Cook.

    Tiffany Cook, PhD

    studies cell type specification using the Drosophila eye as a model. The lab is focuses on gene regulation, and uses a combination of developmental genetics and biochemistry to understand the role of various transcription factors during photoreceptor and lens development.
    Visit the Cook Lab.

    513-636-6991
    tiffany.cook@cchmc.org

    Tiffany Cook, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-6991

    Fax: 513-803-0740

    Email: tiffany.cook@cchmc.org

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    Specialties

    Understanding the molecular basis of eye development; differentiation of color photoreceptor subtypes in the Drosophila retina; cell-specific regulation of opsin gene expression; mechanisms of cell-specific transcriptional activation and repression

    Differentiation of color photoreceptor subtypes in the Drosophila retina; cell-specific regulation of opsin gene expression; mechanisms of cell-specific transcriptional activation and repression

    Visit the Cook Lab.

    Education and Training

    BA: Biology, Summa Cum Laude, Phi Beta Kappa, 1987-1991. 

    PhD: Biomedical Sciences/Molecular Biology, 1991-1997. 

    Postdoctoral fellowships: Gastroenterology, 1997-1999; Molecular Genetics, 1999-2004.

    Publications

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    A photo of Zelia M. Correa.

    Zelia M. Correa, MD, PhD Attending Ophthalmologist, Division of Pediatric Ophthalmology

    is an ocular oncologist and ophthalmic pathologist who has been dedicated to clinical and translational research mainly focusing on uveal melanoma and retinoblastoma. Her primary focuses are development and treatment of metastasis from uveal melanoma, and new advances in management of retinoblastoma.

    513-475-7300
    correazm@uc.edu

    Zelia M. Correa, MD, PhD

    Attending Ophthalmologist, Division of Pediatric Ophthalmology

    Ocular Oncology

    Academic Information

    Associate Professor, UC Department of Ophthalmology

    Phone: 513-475-7300

    Email: correazm@uc.edu

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    Specialties

    Clinical

    Ocular oncology; retinoblastoma and childhood ocular benign and malignant tumors

    Research

    Ocular oncology; ophthalmic pathology

    Biography

    Dr. Correa has been recognized by her academic achievements and her volunteer service/leadership in the profession of ophthalmology. She has received an achievement award (2010) and the international ophthalmologist education award (2009) from the American Academy of Ophthalmology. Additionally, She has been recognized by two Secretariat Awards also from the American Academy of Ophthalmology and has been the youngest Guest of Honor at their National Meeting in 2009. Here in Cincinnati, she has received the Dean’s Award for Excellence in Education (University of Cincinnati College of Medicine) in 2011.

    Education and Training

    Undergraduate: Faculdade Riopretense de Filosofia Ciências e Letras, São José do Rio Preto, Brazil.

    MD: Faculdade Medicina de Rio Preto, São José do Rio Preto, Brazil, 1989.

    Residency: Ophthalmology, Faculdade de Medicina de Marília, Brazil, 1992.       

    Certification: Ophthalmology, 1992.

    Fellowship: Vitreoretinal surgery, Brazil, 1995.

    Fellowship: Ocular oncology, Wills Eye Hospital, Philadelphia,PA 1996.  

    PhD: UNIFESP (Federal university of São Paulo, SP, Brazil), 2003.

    Post-doctoral fellowships: Ophthalmic pathology, Wills Eye Institute, Philadelphia, PA, 2005;

    Ophthalmic pathology and translational research, McGill University-Montreal, QC, Canada, 2006.

    Publications

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    Grants

    Development of a chitosan based intraocular implant slow delivery for methotrexate - RPB - research to prevent blindness. Dec 2012 - Jan 2014.

    Mary Asbury Chair of Ophthalmic Pathology. Sept 2006 – Current.

    A photo of Fumika Hamada, PhD.

    Fumika Hamada, PhD

    is working to identify molecular mechanisms of temperature sensation using the fly brain as a model. We will elucidate how temperature stimuli are relayed and represented in the brain and will uncover the temperature-responsive neural circuits using genetic, behavioral and physiological approaches.
    Visit the Hamada Lab.

    513-803-1662
    fumika.hamada@cchmc.org

    Fumika Hamada, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-1662

    Fax: 513-803-0740

    Email: fumika.hamada@cchmc.org

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    Specialties

    Thermo- and pain sensation in Drosophila

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    Education and Training

    Postdoctoral Fellow: Brandeis University, 2005 - 2009. Harvard Medical School, 2004 - 2005. 

    PhD: Tokyo University of Science, Japan, 2004. 

    BS: Tokyo University of Science, Japan,1999.

    Publications

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    A photo of Virginia Miraldi Utz.

    Virginia A. Miraldi Utz, MD

    is a pediatric ophthalmologist who works closely with faculty within the Ophthalmology and Visual Science Research Department and Department of Human Genetics.  Her research interests are in nosology of ophthalmic genetic disorders and syndromes including retinal dystrophies and mitochondrial disorders. 

    513-636-4751

    Virginia A. Miraldi Utz, MD

    Academic Information

    Assistant Professor, UC Department of Ophthalmology

    Phone: 513-636-4751

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    Specialties

    Pediatric eye diseases such as amblyopia, cataracts and strabismus; diagnosis and management of genetic eye disorders and syndromes (retinal dystrophies such as retinitis pigmentosa, Stargardt disease, ocular malformations and mitochondrial disorders); pediatric uveitis and ocular inflammation.

    Biography

    Dr. Virginia Miraldi Utz, MD, FAAP, is an assistant professor of pediatric ophthalmology at the Abrahamson Eye Institute of Cincinnati Children’s Hospital Medical Center. She completed her undergraduate degree in biochemistry and religious studies at The College of Wooster (Wooster, Ohio) and Kanda University (Chiba, Japan). She received her Doctor of Medicine from Case Western Reserve University School of Medicine in Cleveland, Ohio, where she was served as co-president of the Alpha Omega Alpha Society chapter. During her residency at University Hospitals Case Medical Center, she was awarded the Ocular Immunology and Uveitis Foundation Travel Grant for her basic science research in ocular microbiology and immunology and the Humanism in Ophthalmology Award. She completed her fellowship training in pediatric ophthalmology and adult strabismus at the Cleveland Clinic Cole Eye Institute. She recently completed additional clinical training in the field of ocular inflammation and uveitis preceptorship to serve patients with juvenile idiopathic arthritis and related disorders.

    Dr. Miraldi Utz specializes in the management of pediatric eye disorders such as amblyopia, strabismus, and pediatric cataracts. She has special clinical and research interests in ocular inflammatory disease and ophthalmic genetic disorders, including ocular malformations and retinal dystrophies. Dr. Miraldi Utz has published multiple research articles in peer-reviewed journals, as well as having contributed abstracts and presentations at a number of professional association meetings. She is a peer reviewer for several journals, including Ophthalmic Genetics, Molecular Vision, and British Journal of Ophthalmology. She is a member of American Association for Pediatric Ophthalmology and Strabismus, American Academy of Ophthalmology, American Uveitis Society, Ophthalmic Genetic Study Club, International Society for Genetic Eye Diseases and Retinoblastoma, and Fellow of the American Academy of Pediatrics.

    Education and Training

    Medical School: Case Western Reserve University School of Medicine, Cleveland, OH.

    Residency: Ophthalmology, University Hospitals Eye Institute Case Medical Center, Case Affiliated Hospitals Residency Program, Cleveland, Ohio.

    Fellowship: Pediatric Ophthalmology and Adult Strabismus, Cole Eye Institute, Cleveland Clinic; Cleveland, Ohio.

    Preceptorship: Pediatric Uveitis, The Retina Group, Columbus, OH; Cincinnati Eye Institute, Cincinnati, OH.

    Board Certification: American Board of Ophthalmology, 2013.

    Publications

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    A photo of Saima Riazuddin, PhD.

    Saima Riazuddin, PhD

    is focused on molecular and genetic basis of hearing impairment. For these studies, we utilize large human pedigrees and mutant mouse models. Through genetic screening disease causing mutations are identified in human families. To further understand the underlying cause of deafness in human pedigrees, we generate orthologue mouse models. These mouse models are evaluated for structural, physiological and developmental defects of the inner ear.

    513-803-2888
    saima.riazuddin@cchmc.org

    Saima Riazuddin, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Assistant Professor, UC Department of Otolaryngology – Head and Neck Surgery

    Phone: 513-803-2888

    Fax: 513-803-2899

    Email: saima.riazuddin@cchmc.org

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    Specialties

    Investigating molecular and genetic basis of hearing loss, utilizing human and mouse genetics to identify novel genes and pathways that underlie inherited human hearing impairment.

    Biography

    Saima Riazuddin, PhD, is head of the Laboratory of Molecular Genetics and assistant professor in the Division of Pediatric Otolaryngology - Head and Neck Surgery at the Cincinnati Children’s Research Foundation. She holds secondary appointments in the Division of Opthalmology at the Cincinnati Children’s Research Foundation and the Departments of Otolaryngology and Ophthalmology at the University of Cincinnati.

    Dr. Riazuddin is interested in the molecular and genetic basis of Hearing impairment. She utilizes human and mouse genetics to identify novel genes and pathways that underlie inherited human hearing impairment.

    Education and Training

    BS: University of the Punjab, Lahore, Pakistan, 1995.

    MS: Quaid-i-Azam University, Islamabad, Pakistan, 1998.

    PhD: University of the Punjab, Lahore, Pakistan, 2001.

    Publications

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