Pathology

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    Division Director

    A photo of David Witte.

    David P. Witte, MD Director, Pathology

    513-636-4261
    david.witte@cchmc.org

    David P. Witte, MD

    Director, Pathology

    Director, Mass Spectrometry Laboratory

    Academic Information

    Professor, UC Department of Pathology & Laboratory Medicine

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: david.witte@cchmc.org

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    Specialties

    Molecular pathology; pediatric renal pathology

    Molecular/Developmental Biology

    Education and Training

    MD: University of Cincinnati, Cincinnati, Ohio, 1979.

    Residency: Pediatrics, Washington University, St. Louis, Mo., 1979-1980; Pathology, Washington University, St. Louis, Mo., 1980-1984.

    Fellowship: Pathology, Children's Hospital Medical Center, Cincinnati, Ohio, 1984-1986; Research Scholar, Pathology, Children's Hospital Medical Center, Cincinnati, Ohio, 1986-1989.

    Certification: Anatomic Pathology, American Board of Pathology, 1985; Pediatric Pathology, American Board of Pathology, 1991.

    Faculty

    A photo of Kevin E. Bove.

    Kevin E. Bove, MD

    is currently focused on pathogenesis of biliary atresia and other cholestatic disorders of infancy, with long term research interests in the early stages of childhood neoplasia and childhood diseases of skeletal muscle and heart.

    513-636-4261
    kevin.bove@uc.edu

    Kevin E. Bove, MD

    Academic Information

    Professor, UC Department of Pediatrics

    Professor, UC Department of Pathology & Laboratory Medicine

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: kevin.bove@uc.edu

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    Specialties

    Research Interests

    Dr. Bove's current research focus is on pathogenesis of biliary atresia and other cholestatic disorders of infancy. He has long term research interests in the early stages of childhood neoplasia and childhood diseases of skeletal muscle and heart.

    Clinical Interests

    Dr. Bove has been a career academic pediatric pathologist at Cincinnati Children's since 1968. He functions as a surgical pathologist, autopsy consultant and electron microscopist with diverse clinical interests. His collaborations with faculty and fellows in many divisions have resulted in more than 180 peer-reviewed and more than 120 publications.

    Biography

    Kevin E. Bove, MD, has 32 years experience as a pediatric pathologist at Cincinnati Children's Hospital Medical Center.

    Dr. Bove has achieved national recognition as an expert in tumors; neuromuscular diseases; liver diseases of children and performance / interpretation of pediatric autopsies.

    Dr. Bove has and continues to be involved in leadership positions in the Society for Pediatric Pathology and the College of American Pathologists.

    Education and Training

    MD: State University of New York, Buffalo, NY.

    Residency: Rotating Intern, Cincinnati General Hospital, 1961-1962; Pathology, Cincinnati General Hospital, 1962-1966.

    Certification: American Board of Pathology in Anatomic and Clinical Pathology, 1967 and 1968; Pediatric Pathology, 1990.

    A photo of Margaret Collins.

    Margaret H. Collins, MD

    is a pediatric pathologist specializing in pediatric gastrointestinal pathology, especially eosinophilic gastrointestinal diseases. She has provided biopsy analyses, including primary study endpoints, for several clinical trials testing novel therapies to treat eosinophilic esophagitis in children. She also performs clinical research in other disorders of bowel immunity, and bowel motility disorders.

    513-636-4261
    margaret.collins@cchmc.org

    Margaret H. Collins, MD

    Academic Information

    Professor, UC Department of Pathology & Laboratory Medicine

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: margaret.collins@cchmc.org

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    Specialties

    Clinical Interests

    Pediatric gastrointestinal pathology; eosinophilic gastrointestinal diseases; biopsy analyses; primary study endpoints; novel therapies to treat eosinophilic esophagitis in children; disorders of bowel immunity; bowel motility disorders

    Biography

    In 2011, Dr. Collins was named one of the Top Doctors in Pathology by U.S. News & World Report.

    Education and Training

    BS: Fordham University, NY, 1972.

    MD: Georgetown University, Washington, D.C., 1977.

    Residency: Pathology, New York Hospital, NY, 1977-80; Pathology, Columbia-Presbyterian Medical Center, NY, 1980-83.

    Fellowship: Research, New York Lung Association, Columbia-Presbyterian Medical Center, N.Y., 1983-85; Research, American Lung Association, Columbia-Presbyterian Medical Center, NY, 1985-87.

    Certification: Pathology, 1981; Pediatric Pathology, 1991.

    Publications

    View PubMed Publications
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    Anita Gupta, MD

    is a career academic pediatric pathologist at who functions as a surgical pathologist and electron microscopist. Current research focuses on liver tumors, cardiac transplants, vascular anomalies, and cilia abnormalities.

    513-636-4261
    anita.gupta@cchmc.org

    Anita Gupta, MD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: anita.gupta@cchmc.org

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    Specialties

    Clinical Interests

    Pediatric pathology; surgical pathology; electron microscopy.

    Research Interests

    Liver tumors; cardiac transplants; vascular anomalies; cilia abnormalities.

    Education and Training

    MD: Mahadevappa Rampure Medical College, Gulbarga, Karnataka, India, 1997.

    Residency: Northwestern Memorial Hospital, Chicago, IL, 2001-2005.

    Fellowship: The Children's Hospital, Denver, CO, 2006.

    Publications

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    Richard L. McMasters, MD Staff Pathologist

    has a research interest in childhood leukemia, lymphoma and bone marrow failure syndromes. His current focus is on applications of flow cytometry in the diagnosis and management of these disorders.

    513-636-4261
    richard.mcmasters@cchmc.org

    Richard L. McMasters, MD

    Staff Pathologist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: richard.mcmasters@cchmc.org

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    Specialties

    Research Interests

    Dr. McMasters has a research interest in childhood leukemia, lymphoma and bone marrow failure syndromes. His current focus is on applications of flow cytometry in the diagnosis and management of these disorders.

    Clinical Interests

    Dr. McMasters joined Cincinnati Children's in 2008. His main clinical interests are hematopathology and general surgical pathology. He is the laboratory director at Cincinnati Children's Liberty Campus.

    Education and Training

    MD: Baylor College of Medicine, 1994.

    Residency: Harbor-UCLA Medical Center, 2002.

    Fellowships: Children's Hospital Los Angeles, 2003; LAC-USC Medical Center, 2004; Akron Children's Hospital, 2005.

    Certification: Anatomic and Clinical Pathology, 2003; Hematology (Pathology), 2004; Pediatric Pathology, 2005.
    A photo of Lili Miles, MD.

    Lili Miles, MD Staff Pathologist

    is interested in neuropathology, neuromuscular diseases, and NASH. Examples of my current research activities include: pediatric brain tumors; mitochondrial changes in epileptic brain tissue; pediatric muscle diseases; and liver biopsies in pediatric NASH.

    513-636-4261
    lili.miles@cchmc.org

    Lili Miles, MD

    Staff Pathologist

    Director, Fellowship Training Program

    Academic Information

    Associate Professor, Division of Pediatric Pathology

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: lili.miles@cchmc.org

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    Specialties

    Clinical Interests

    Pediatric pathology; pediatric neuropathology; pediatric neuromuscular disease

    Research Interests

    Mitochondrial diseases; coenzyme Q10; pediatric brain tumors; classification and grading of cortical dysplasia; hepatic pathology in pediatric NASH patients and animal models

    Education and Training

    MD: The Shanghai Second Medical University, Shanghai, China, 1986.

    Residency: University of Cincinnati, Cincinnati, OH, 2001.

    Fellow: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2003.

    Publications

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    A photo of Joel E. Mortensen.

    Joel E. Mortensen, PhD Director, Diagnostic Infectious Diseases Testing Laboratory (Microbiology and Virology)

    currently focuses is antimicrobial susceptibility testing of fastidious pediatric pathogens.

    513-636-5310
    joel.mortensen@cchmc.org

    Joel E. Mortensen, PhD

    Director, Diagnostic Infectious Diseases Testing Laboratory (Microbiology and Virology)

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-5310

    Fax: 513-636-8850

    Email: joel.mortensen@cchmc.org

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    Specialties

    Research Interests

    Dr. Mortensen's current research focus is antimicrobial susceptibility testing of fastidious pediatric pathogens.

    Clinical Interests

    Dr. Mortensen is a career academic clinical microbiologist in the Department of Pathology and Laboratory Medicine at Cincinnati Children's since 1991. Beyond providing consultation to the medical staff in Clinical Microbiology, his clinical interests include the application of rapid testing methods into the clinical microbiology laboratory and outpatient settings and LEAN manufacturing processes applied to Clinical Microbiology. His collaborations with faculty and fellows have resulted in more than 100 peer-reviewed publications, case studies and text chapters.

    Education and Training

    BS: Mount Union College, Alliance, Ohio, 1979.

    PhD: The Ohio State University, Columbus, Ohio, 1983.

    Residency: Accredited Postdoctoral Residence Program in Medical and Public Health Microbiology; Baylor College of Medicine, University of Texas Medical School, Pathology, Houston, Texas 1983-85.

    Certification: Certified Laboratory Consultant, American Medical Technologists, 1998.

    Publications

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    Shiva K. Shanmukhappa, DVM, PhD, Diplomate ACVP

    is an assistant professor in the Division of Pathology with board certification in comparative veterinary anatomic pathology. He provides pathology support to investigators and also is core pathologist for the Digestive Health Center. His primary research interests have been in studying molecular mechanisms involved in liver repair and regeneration, NASH and  metabolic complications in HIV. Additional research interests include virus host interaction, tumor development, neurodegenerative diseases and aging.

    513-803-4289
    shiva.shanmukhappa@cchmc.org

    Shiva K. Shanmukhappa, DVM, PhD, Diplomate ACVP

    Academic Information

    Assistant Professor, UC Department of Pathology & Laboratory Medicine

    Phone: 513-803-4289

    Email: shiva.shanmukhappa@cchmc.org

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    Specialties

    Research

    Liver repair and regeneration; NASH; metabolic complication of HIV; sickle cell disease; nephropathy.

    Biography

    Shiva Kumar Shanmukhappa joined the Cincinnati Children's Division of Pathology and Laboratory Medicine in 2012 as an assistant professor of pathology overseeing the research pathology core.

    From 2009-2012, Dr. Shanmukhappa was a comparative pathology fellow Division of Comparative Pathology, New England Primate Research Center, Harvard Medical School. 

    Dr. Shanmukhappa was research fellow in Division of Gastroenterology, Hepatology and Nutrition from 2003 to 2009 where he primarily worked on understanding the molecular mechanism involved in liver repair and regeneration as well as the induction of pancreatic cells in liver during defective liver repair. He identified the role of plasmin in liver repair. He has shown that plasmin mediates liver repair through the activation of HGF-MET signaling mainly affecting cell motility.

    Dr. Shanmukhappa has an active research career with his primary interests in molecular control of liver repair, regeneration, biliary atresia, NASH and metabolic complications of HIV.

    Education and Training

    DVM: Veterinary College, University of Agricultural Sciences, Bangalore, India,1996.

    PhD: Department of Veterinary Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS, 2002.

    Residency: Comparative Pathology, New England Primate Research Center, Harvard Medical School, Southborough, MA.

    Certification: Veterinary Anatomic Pathology, 2013.

    Publications

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    Grants

    12.5 % effort, Digestive Health Center, Cincinnati Children’s Hospital Medical Center. Public Health Service Grant. Jan 2013 – Current. P30 DK078392.
    A photo of Jerzy Stanek.

    Jerzy W. Stanek, MD, PhD

    focuses on placental pathology, particularly relating to various placental patterns of acute and chronic placental hypoxic injury. Another research area is investigation of causes of fetal perinatal mortality, particularly of infectious origin.

    513-636-8158
    jerzy.stanek@cchmc.org

    Jerzy W. Stanek, MD, PhD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-8158

    Fax: 513-636-3924

    Email: jerzy.stanek@cchmc.org

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    Specialties

    Placental pathology; pathology of in utero hypoxia

    Education and Training

    MD: College of Medicine, Jagiellonian University, Kraków, Poland, 1968.

    PhD: College of Medicine, Jagiellonian University, Kraków, Poland, 1974
    Residencies:  University Hospital of Obstetrics and Gynecology, Jagiellonian University, Kraków, Poland, 1970-1976; Georgetown University Medical Center, Washington, DC, and Rush Presbyterian-St.Luke's Medical Center, Chicago, IL, 1990-1994.

    Fellowship: Reproductive Endocrinology, University Hospital of Obstetrics and Gynecology, Kraków, Poland; 1976-1977.

    Certifications: Obstetrics and Gynecology, Polish Board of Obstetrics and Gynecology, 1976; Endocrinology, Postgraduate Medical Center, Poland, 1977; Anatomic and Clinical Pathology, American Board of Pathology, 1994; Pediatric Pathology, American Board of Pathology, 1999.

    Publications

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    A photo of Keith Stringer.

    Keith F. Stringer, MD Pathologist

    focuses on the application of the techniques of modern morphology in assessing diseased tissues. His work with these techniques, such as immunofluorescence microscopy and in situ hybridization, have contributed to dozens of publications elucidating features of the pathogenesis of allergic, neoplastic, developmental, and other disease processes.

    513-636-4261
    keith.stringer@cchmc.org

    Keith F. Stringer, MD

    Pathologist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4261

    Fax: 513-636-3924

    Email: keith.stringer@cchmc.org

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    Specialties

    Microscopic techniques for assessing mRNA expression; protein production and cellular identity in eukaryotic tissues; stem cell development and differentiation using animal models such as the zebrafish

    Education and Training

    BSc: University of British Columbia, Vancouver, British Columbia, Canada.

    MSc: University of Toronto, Toronto, Ontario, Canada.

    MD: University of Calgary, Calgary, Alberta, Canada, 1995.

    DABP: Anatomic and Pediatric Pathology.

    Publications

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    A photo of Peter Tang.

    Peter H. Tang, PhD Director, Special Chemistry

    focuses on the diagnosis of mitochondrial dysfunction, metabolic disorder, neurodegenerative disease, hemoglobin disorder, neurogenesis, and therapeutic drug monitoring. He has long term research interests in inventing novel approaches for clinical diagnosis by using HPLC and LC/MS.

    513-636-3357
    peter.tang@cchmc.org

    Peter H. Tang, PhD

    Director, Special Chemistry

    Clinical Chemist

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-3357

    Fax: 513-636-8850

    Email: peter.tang@cchmc.org

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    Specialties

    Clinical Interests

    In vitro diagnostics; disease monitoring procedures

    Research Interests

    Mitochondrial dysfunction; metabolic disorders; neurodegenerative diseases; hemoglobin disorders; neurogenesis; and therapeutic drug monitoring

    Education and Training

    PhD: Analytical Chemistry, University of Cincinnati, Cincinnati, OH, 1990.

    MS: Biochemistry, Northeast Louisiana University, Monroe, LA, 1985.

    BS: Pharmacy, Taipei Medical College, Taipei, Taiwan, 1978.

    Publications

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    A photo of Kathryn Wikenheiser-Brokamp.

    Kathryn A. Wikenheiser-Brokamp, MD, PhD Director, Residency Research Program

    investigates pediatric and adult lung diseases, including cancer, which are characterized by aberrant epithelial cell growth and differentiation. A major focus is the molecular mechanisms underlying Rb/p16, p53, and Dicer1 pathway function in lung development and the pathogenesis of lung disease. The ultimate goal is to identify new diagnostic, prognostic and therapeutic targets for common pulmonary disorders.

    513-803-0239
    kathryn.wikenheiser-brokamp@cchmc.org

    Kathryn A. Wikenheiser-Brokamp, MD, PhD

    Director, Residency Research Program

    Academic Information

    Assistant Professor, UC Department of Pathology & Laboratory Medicine

    Phone: 513-803-0239

    Fax: 513-636-7868

    Email: kathryn.wikenheiser-brokamp@cchmc.org

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    Specialties

    Pulmonary pathology; pediatric and adult lung diseases

    Education and Training

    BS: Mathematics/Natural Science, Secondary Education Minor, University of Mary, Bismarck, ND, 1988.

    PhD: Developmental Biology, Developmental Biology and Medical Science Scholars Programs, University of Cincinnati, Cincinnati, OH, 1994.

    MD: Medical Science Scholars Program, University of Cincinnati, Cincinnati, OH, 1996.

    Residency: Anatomic Pathology, Department of Pathology and Immunology, Washington University-Barnes/Jewish Hospital, St. Louis, MO, 1996-2002.

    Clinical Training/Postdoctoral Research: Department of Pathology and Immunology, Washington University, St. Louis, MO, 1999-2002.

    Licensure: State of Ohio, 2003.

    Certification: Anatomic Pathology, The American Board of Pathology, 1999.

    Publications

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