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The research focus of the Division of Perinatal Biology at Cincinnati Children’s Hospital Medical Center is to understand inflammation and injury in preterm infants as it relates to:
Postnatal exposure to inflammatory stimuli (e.g., mechanical ventilation, oxygen)
Researchers in the division use animal models to understand the mechanisms of lung disease and fetal systemic inflammation in infants, with the goal of finding better therapeutic modalities for premature infants.
The Division of Perinatal Biology laboratory collaborates with other divisions and laboratories at Cincinnati Children’s and with international colleagues in Australia and the Netherlands. The preterm sheep model is the main model used in our research, with mouse and rat models additionally available for support. Our primary research funding comes from the National Institutes of Health.
Our current research projects include:
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