• Research Faculty

    Researchers with the Perinatal Institute at Cincinnati Children’s Hospital Medical Center have expertise in the social sciences, public health, epidemiology, process and quality improvement, health care economics and advocacy policy, as well as the more traditional avenues of basic science, translational research and clinical trials. Insights from our research can be directly applied to the clinical challenges faced by infants during the perinatal period.

  • A photo of James M. Greenberg.

    James M. Greenberg, MD Co-Director, Perinatal Institute

    investigates the developmental biology of pulmonary vascular development, including how vascular endothelial growth factor (VEGF) mediates pulmonary vascular, lymphatic and airway development. He studies how VEGF mediates organization of pulmonary vasculature during late fetal life as well as how certain proteins implicated in axonal guidance during central nervous system development also direct developmental processes in the lung.


    A photo of Louis Muglia.

    Louis J. Muglia, MD, PhD Co-Director, Perinatal Institute

    is a pediatric endocrinologist whose research efforts seek to define the mechanisms controlling the timing for birth in humans to prevent or better treat human preterm labor. Recent efforts analyze the contribution of genetic determinants to preterm birth. A second area of investigation is elucidation of the molecular pathways involved in the behavioral and neuroendocrine responses to stress.
    Visit the Muglia Lab


    A photo of Jeffrey Whitsett.

    Jeffrey A. Whitsett, MD Co-Director, Perinatal Institute

    investigates the hierarchy of transcriptional controls and signaling cascades which determine commitment of progenitor cells that produce the differentiated epithelial cells lining the primordial and mature respiratory tract. The goal of his research is to provide insight into the pathogenesis of acute and chronic lung disorders. The role of surfactant in innate host defense and lung function is also an ongoing interest.
    Visit the Whitsett Lab.


    A photo of Bruce Aronow.

    Bruce J. Aronow, PhD Co-director, Computational Medicine Center

    focuses his research on unraveling the role and mechanism by which the functional capabilities of the human genome shape human health and the body’s ability to adapt to stressful challenges. With the co-leadership of Anil Jegga, DVM, his lab is using a variety of available data on structural and functional genomics and biological systems to form models of how biological systems assemble, adapt and become impaired in disease.
    Visit the Aronow/Jegga Lab.


    A photo of Samantha Brugmann.

    Samantha A. Brugmann, PhD Member, Division of Plastic Surgery

    is a developmental biologist who aims to understand craniofacial development and elucidate the molecular basis for diseases that affect the craniofacial complex. Furthermore, Dr. Brugmann attempts to understand the forces that help pattern the face during normal and abnormal development she utilizes various model systems with unique facial morphologies.

    Visit the Brugmann Lab.


    A photo of Kenneth Campbell.

    Kenneth J. Campbell, PhD

    studies the molecular genetic control of mouse forebrain development with a particular focus on the generation of neuronal diversity in the ventral telencephalon.


    A photo of Sang-Wook Cha.

    Sang-Wook Cha, PhD

    investigates how Wnt/Planar Cell Polarity (PCP) signaling between lateral plate mesoderm (LPM) and endoderm regulates apicobasal polarity (ABP) of intestinal epithelium and controls radial-intercalation and gut elongation. Dr. Cha uses both amphibian and mouse/human organoids as the model systems.


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    Vaughn G. Cleghon, PhD

    is interested in understanding the role of protein kinases in development and disease. His lab uses molecular biology, tissue culture, Drosophila genetics and bioinformatics to better understand fundamental mechanisms involved in the regulation of protein kinase activity. 
    Visit the Cleghon Lab.


    A photo of Roger Cornwall.

    Roger Cornwall, MD Clinical Director, Pediatric Orthopaedic Surgery

    investigates the neurological control of postnatal muscle growth and development. The goal of his research is to identify novel physiological treatments for pediatric neuromuscular contractures.

    Visit the Cornwall Lab.


    A photo of Steven Crone.

    Steven A. Crone, PhD

    focuses his research around understanding how neurons form functioning motor circuits during development and how the function (or dysfunction) of motor circuits impacts neurodegenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy.
    Visit the Crone Lab.