Brugmann Lab

K. Lenton, A.W. James, A. Manu, S.A Brugmann, D. Birker, E.R. Nelson, P. Leucht, J.A. Helms, M.T. Longaker. (2011). Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling.Genesis.. 49(10):784-96 PMID: 21557453 

B. Levi, A.W. James, E.R. Nelson, S.A. Brugmann, M. Sorkin, A. Manu, M.T. Longaker. (2011). Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 127(3):1182-90. PMID: 21364421

N.A. Zaghloul and S.A. Brugmann. (2011). The emerging face of primary cilia. Genesis. 49(4):231-46. PMID: 21305689

A. Rada-Iglesias, R. Bajpai, T. Swigut, S.A.Brugmann, R.A. Flynn, J. Wysocka. (2011). A unique chromatin signature uncovers early developmental enhancers in humans. Nature.470(7333):279-83. PMID: 21160473

D.R. Cordero, S. Brugmann, Y. Chu, R. Bajpai, M. Jame, J.A. Helms. (2011). Cranial neural crest cells on the move: Their roles in craniofacial development. Am J Med Genet A. 155(2):270-9. PMID:21271641

B. Levi, S. Brugmann,  M.T. Longaker. (2010).Discussion: Hes1 is required for the development of craniofacial structures derived from ectomesenchymal neural crest cells.J Craniofac Surg. 21(5):1450-1. PMID:20818250 

S.A.Brugmann, D.R.Cordero, J.A. Helms. (2010). Craniofacial ciliopathies: A new classification for craniofacial disorders.Am J Med Genet Part A. 152A:2995–3006. PMID: 21108387

S.A. Brugmann, N. C. Allen, Z. Mekonnen, E. Madan, J.A. Helms.(2010). A primary cilia-dependent etiology for midline facial disorders. Human Molecular Genetics.19(8):1577-92. PMID:20106874

S.A. Brugmann*, K.A. Powder*, N. Young, L.H. Goodnough, S.M. Hahn, A.W. James, J.A. Helms, M. Lovett. (2010).Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders. Human Molecular Genetics. 19(5):920-30. PMID:20015954

C.T. Anderson, A.B. Castillo, S.A. Brugmann, J.A. Helms, C.R. Jacobs, T. Sterns. (2008). Primary Cilia: Cellular Sensors for the Skeleton. Anatomical Record. 291(9):1074-8. PMID:18727074

G. Schlosser, T. Awtry, S.A. Brugmann, E. D. Jensen, K. Neilson, G. Ruan, A. Stammler, D. Voelker, B. Yan, C. Zhang, M. W.  Klymkowsky, S. A. Moody. (2008). Eya1 and Six1 promote neurogenesis in the cranial placodes in a SoxB1-dependent fashion. Developmental Biology. 320:199-214. PMID:18571637

J.A. Helms and S.A. Brugmann. (2007). The origins of species-specific facial morphology: The proof is in the pigeon. Integrative and Comparative Biology. 51(1):1-5. URL http://icb.oxfordjournals.org/cgi/ content/full/icm051v1

S.A. Brugmann, L.H. Goodnough, A. Gregorieff, P. Leucht, D. ten Berge, C. Fuerer, H. Clevers, R. Nusse, and J.A. Helms. (2007). Wnt signaling mediates regional specification in the vertebrate face. Development. 134:3283-3295. PMID:17699607

S.A. Brugmann, J. Kim and J.A. Helms. (2006).Looking different: towards an understanding diversity in facial form. American Journal of Medical Genetics. 140(23):2521-9. PMID:16838331

S.A. Brugmann, M.D. Tapadia and J.A. Helms. (2006).  The Molecular Origins of Species-Specific Facial Pattern. Current Topics in Developmental Biology. 73:1-42. PMID:16782454

S.A. Brugmann and S.A. Moody. (2005). Induction and specification of the vertebrate ectodermal placodes: precursors of the cranial sensory organs. Biology of the Cell.97(5):303-19. (Cover). PMID:15836430

S.A. Brugmann, P.D. Pandur, K.L. Kenyon, F. Pignoni and S.A. Moody. (2004). Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. Development. 131(23):5871-81. PMID:15525662

M. Jame, S.A. Brugmann and J.A. Helms. “Embryology of the craniofacial complex” Neligan Plastic Surgery 3^rd Edition Vol. 3 Head & Neck. Ed. Joe Losee. Elsevier, New York..

S.A. Brugmann, R.R. Amasha, D.M. Gupta, J.A. Helms. “Craniofacial Patterning and Dysmorphologies” Craniofacial Growth and Development. Ed. Jeremy J. Mao and Hyun-duck Nah. Iowa State University Press. 2009. 320p.

J. A. Helms, S.A. Brugmann, and D.R. Cordero. “Shh and Other Genes and the Holoprosencephaly Malformation Sequence” Inborn Errors of Development Second Edition. Ed. Charles J. Epstein, Robert P. Erickson, and Anthony Wynshaw-Boris. Oxford University Press, London. 2008. 291-300.

S.A. Brugmann and J.A. Helms. "Craniofacial formation and congenital defects" Principles of Developmental Genetics. Ed. Sally A. Moody. Elsevier, New York. 2007. 656-679.