(All fields required)
Please enter a valid email.
Please enter your name.
Christopher B. Gordon, MD
Assistant Professor, Division of Pediatric Surgery
Maercks RA, Taylor JA, Gordon CB. Endoscopic monobloc advancement with ultrasonic osteotomy: a feasibility study. J Craniofac Surg. 2010 Mar;21(2):479-82.Taylor JA, Maercks RA, Runyan CM, Jones DC, Gordon CB. Endoscopically assisted Le Fort III osteotomy using an ultrasonic scalpel: a feasibility study in cadavers. J Craniofac Surg. 2009 Nov;20(6):2211-4.Taylor JA, Maercks RA, Jones DC, Gordon CB. Endoscopically assisted Le Fort I osteotomy using an ultrasonic scalpel: a feasibility study in cadavers. J Oral Maxillofac Surg. 2009 Jul;67(7):1420-4.
Yu Lan, PhD
Associate Professor, UC Department of Pediatrics
Yu Lan, PhD, is a developmental geneticist interested in understanding the genetic basis and developmental mechanisms of structural birth defects. Cleft palate is one of the most common birth defects in humans. To understand the molecular and cellular mechanisms of cleft palate pathogenesis, we have been investigating the molecular pathways governing normal palate development in the laboratory mice.
Through gene expression screening, we have identified several putative transcription factor genes with distinct and dynamic expression patterns in the developing mouse palate. Using the gene targeting technology, we have generated mice carrying null or conditional null mutations in some of these transcription factor genes. Analyses of the mutant mice revealed that several of these transcription factors, such as Osr1 and Osr2, play essential roles in palate development. Ongoing investigations focus on delineating the molecular pathways involving these factors in palate development using a combination of genetic, embryological, and biochemical approaches.
PhD: University of Maine, Orono, ME.
Post-doc training: Wesleyan University, Middletown, CT; The Jackson Laboratory, Bar Harbor, ME.
Genetic Basis of Cleft Lip and Palate. Co-Investigator. National Institutes of Health. Apr 2003 - Jan 2013. #R01 DE015207.
Molecular Genetic Analysis of Craniofacial Development. Co-Investigator. National Institutes of Health. Apr 2000 - Jun 2015. #R01 DE013681.
3333 Burnet Avenue, Cincinnati, Ohio 45229-3026 | 1-513-636-4200 | 1-800-344-2462 | TTY:1-513-636-4900
New to Cincinnati Children’s or live outside of the tri-state area? 1-877-881-8479
© 1999-2013 Cincinnati Children's Hospital Medical Center