Plastic Surgery

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    Faculty

    A photo of Samantha Brugmann.

    Samantha A. Brugmann, PhD

    is a developmental biologist who aims to understand craniofacial development and elucidate the molecular basis for diseases that affect the craniofacial complex. Furthermore, Dr. Brugmann attempts to understand the forces that help pattern the face during normal and abnormal development she utilizes various model systems with unique facial morphologies.

    Visit the Brugmann Lab.

    513-636-7678
    samantha.brugmann@cchmc.org

    Samantha A. Brugmann, PhD

    Academic Information

    Assistant Professor, UC Department of Surgery

    Phone: 513-636-7678

    Email: samantha.brugmann@cchmc.org

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    Specialties

    Craniofacial development

    Visit the Brugmann Lab.

    Biography

    Samantha A. Brugmann, PhD, is an assistant professor of pediatrics in the Divisions of Plastic Surgery and Developmental Biology. She received her BS in cell and molecular biology in 1998 from Tulane University in New Orleans, LA. She then moved to Washington, DC to study cranial sensory placode development in Xenopus laevis at George Washington University. After receiving her PhD in genetics from George Washington University in 2004, she moved to Stanford, CA to do her postdoctoral research in craniofacial development at Stanford University. While at Stanford she received a Ruth L. Kirschstein National Research Service Awards for Individual Postdoctoral Fellows (F32) in 2006, a Pediatric Research Fund-Child Health Research Program Grant in 2009 and a NIH Pathway to Independence Award (K99/R00) in 2010. She joined Cincinnati Children’s Hospital Medical Center in January 2011 to study craniofacial development and disease.

    Education and Training

    BS: Tulane University, New Orleans, LA, 1998.

    PhD: George Washington University, Washington DC, 2004.

    Fellowship: Stanford University, Stanford, CA, 2004-2010.

    Publications

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    Haithem M. Elhadi Babiker, MD, DMD

    works in the upper airway center to develop protocols for management of pediatric sleep apnea syndrome. His other interests include reconstruction of critical mandibular defects using stem cells and cadaveric bone.

    513-636-4141
    haithem.elhadi@cchmc.org

    Haithem M. Elhadi Babiker, MD, DMD

    Academic Information

    Assistant Professor, UC Department of Surgery

    Phone: 513-636-4141

    Email: haithem.elhadi@cchmc.org

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    Specialties

    Clinical

    Pediatric obstructive sleep apnea syndrome; complex upper airway problems

    Research

    Craniofacial biology

    Biography

    Dr. Elhadi Babiker, MD, DMD, holds a double degree in medicine and dentistry. In addition, he is trained in both plastic surgery and in oral and maxillofacial surgery. He has completed fellowship training in craniofacial surgery. This training places him among an elite group of surgeons in the USA and around the world.

    Education and Training

    MD: Kasturba Medical College, Manipal, India.

    Residency: University of Cincinnati Plastic Surgery, General Surgery and Oral Maxillofacial Surgery, Cincinnati, OH.

    Fellowship: Pediatric and Craniofacial Plastic Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

    Publications

    A photo of Rulang Jiang.

    Rulang Jiang, PhD

    is a developmental biologist directing research programs in craniofacial biology. His lab generates and uses mutant mouse models to investigate the genetic and developmental basis of craniofacial birth defects, including cleft lip, cleft palate, tooth defects, and other craniofacial deformities. His lab also studies development of joints, including long bone joints in the limb and the temporomandibular joint of the jaw.

    Visit the Jiang Lab.

    513-636-3212
    rulang.jiang@cchmc.org

    Rulang Jiang, PhD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-3212

    Email: rulang.jiang@cchmc.org

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    Education and Training

    BS: Nanjing Normal University, Nanjing, China, 1984.

    MS: Genetics, Chinese Academy of Sciences, Beijing, China, 1987.

    PhD: Wesleyan University, Middletown, CT, 1995.

    Publications

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    A photo of Donna Jones.

    Donna C. Jones, PhD

    investigates questions regarding the determinants of bone development, function and shape. In particular, she focuses on the influences of ontogeny, function and evolution on craniofacial morphology. The goal of her research is to assist clinicians treating children with craniofacial abnormalities, either congenital or acquired, through translational and laboratory-based research endeavors.

    513-803-0383
    donna.jones1@cchmc.org

    Donna C. Jones, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Assistant Professor, UC Department of Surgery

    Phone: 513-803-0383

    Email: donna.jones1@cchmc.org

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    Biography

    Translational: Using shape analysis, we are characterizing quantifiable growth curves of craniofacial shape in children from three dimensional photographs. Results from this project are intended for use by clinicians during repair or reconstruction of facial features in future pediatric patients.

    Bench research: Working with in vitro cells and in vivo mouse models, the lab is examining how the interaction of muscle force influences the developing shape of bone, particularly in the mandible. Using a variety of cell markers, tension sensors, and morphological investigations, this research aims to improve our understanding of the cause of developmental abnormalities of the lower jaw, to hopefully reduce the need for surgeries and long hospital stays in children affected with these disorders.

    Education and Training

    BS: State University of New York, College at Fredonia, Fredonia, NY, 1995.

    MS: University of Rochester, Rochester, NY, 1998.

    PhD: University of Cincinnati, Cincinnati, OH, 2004.

    PostDoc: Johns Hopkins, Baltimore, MD, 2007.

    Publications

    A photo of Yu Lan.

    Yu Lan, PhD

    is interested in understanding the genetic basis and developmental mechanisms of structural birth defects. Specifically, Dr. Lan investigates the molecular pathways governing normal palate development in laboratory mice. Her ongoing investigations focus on delineating the molecular pathways involving these factors in palate development using a combination of genetic, embryological, and biochemical approaches.

    513-803-7842
    yu.lan@cchmc.org

    Yu Lan, PhD

    Academic Information

    Associate Professor, UC Department of Surgery

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7842

    Email: yu.lan@cchmc.org

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    Biography

    Yu Lan, PhD, is a developmental geneticist interested in understanding the genetic basis and developmental mechanisms of structural birth defects. Cleft palate is one of the most common birth defects in humans. To understand the molecular and cellular mechanisms of cleft palate pathogenesis, we have been investigating the molecular pathways governing normal palate development in the laboratory mice.

    Through gene expression screening, we have identified several putative transcription factor genes with distinct and dynamic expression patterns in the developing mouse palate. Using the gene targeting technology, we have generated mice carrying null or conditional null mutations in some of these transcription factor genes. Analyses of the mutant mice revealed that several of these transcription factors, such as Osr1 and Osr2, play essential roles in palate development. Ongoing investigations focus on delineating the molecular pathways involving these factors in palate development using a combination of genetic, embryological, and biochemical approaches.

    Education and Training

    PhD: University of Maine, Orono, ME.

    Post-doc training: Wesleyan University, Middletown, CT; The Jackson Laboratory, Bar Harbor, ME.

    Publications

    Grants

    Genetic Basis of Cleft Lip and Palate. Co-Investigator. National Institutes of Health. Apr 2003 - Jan 2013. #R01 DE015207.

    Molecular Genetic Analysis of Craniofacial Development. Co-Investigator. National Institutes of Health. Apr 2000 - Jun 2015. #R01 DE013681.

    A photo of Marty Visscher.

    Marty O. Visscher, PhD

    studies the development and adaptation of the skin barrier in premature and full term infants, the biology of vernix caseosa, skin barrier repair, the effect of topical emollient therapy to reduce infant mortality, and irritant contact dermatitis in health care.  She uses color, three dimensional thermal skin imaging and skin biomarker analysis to quantify treatment response in infantile hemangiomas, wounds and scars.

    Marty O. Visscher, PhD

    Academic Information

    Professor, UC Department of Surgery

    Professor, UC Department of Pediatrics

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    Specialties

    Skin research; infant skin development; effects of environment and skin treatment products on the skin;

    Education and Training

    PhD: Indiana University, Bloomington, IN.

    Publications

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