Seid Lab

  • Flexible Lifestyles Empowering Change (FL3X)

    Collaborations with Division of Endocrinology and Larry Dolan

    Low income and minority adolescents with type 1diabetes (T1D) commonly have poor glycemic control and an adverse cardiovascular disease (CVD) risk profile. There is a critical need to develop and test interventions to improve diabetes self-management and health outcomes for these high-risk youth.

    This study is a pilot and feasibility study of DM-Health, an integrated, evidence-based diabetes self-management intervention that is coherent and user-friendly and takes advantage of state-of-the-art technologies and behavioral strategies. The intervention is based on behavioral approaches (motivational interviewing, problem solving skills training, and behavioral family systems therapy) and communication technology (cell phone based information exchange); each previously shown by our research team to be efficacious.

    Aims

    Specific aims are:

    1. Document the feasibility of the DM-Health trial. We will refine strategies for optimal recruitment and retention and establish administrative, central laboratory, data management, and data analysis systems necessary to the efficient execution of a multi-site clinical trial.
    2. Determine short-term efficacy and potential effect size of the DMHealth intervention. We will assess primary (A1c) and secondary (CVD risk factors, health-related quality of life) outcomes, as well as potential mediators (diabetes self-management behaviors, family communication patterns, problem solving skills) at baseline and 4 months.
    3. Document DM-Health intervention fidelity and acceptability across demographic subgroups and sites.
 
  • FL3X logo
    FL3X logo