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Pulmonary Medicine

Pulmonary Medicine

 

Significant Accomplishments

Pulmonary Outcomes and Quality of Care Research 

An active program of pulmonary outcomes research unites clinical and research faculty as well as clinical staff in advancing the science of improving outcomes for children with pulmonary disease. Research is supported by divisional funding, Cincinnati Children’s Place Outcomes Research Awards and the National Institutes of Health.  Members of the Pulmonary Outcomes Research Lab presented at national and international meetings this year and have published peer-reviewed articles. Highlights from this research group include: demonstrating the effectiveness of a common cystic fibrosis treatment using the national CF Foundation database; determining the relationship between physician behaviors and patient adherence using video recordings; understanding how parents cope with the diagnosis of their child and the role that spirituality and religion play in family adherence to the medical regimen; documenting the impact of scoliosis surgery on lung function; and testing interventions using text messaging to improve adherence for adolescents with asthma. This research aims to increase the division’s capability for improvement and develop knowledge and interventions to improve outcomes. 

Cystic Fibrosis Clinical and Translational Research

John “JP” Clancy, MD, joined the Pediatric Pulmonary Division in January 2011.  He served as the division chief of pediatric pulmonology at the University of Alabama at Birmingham prior to joining the Cincinnati Children’s faculty, and upon his arrival he has been appointed the Thomas Boat endowed chair and director of CF clinical and translational research.  He oversees the CFF-Therapeutic Development Network Translational Research Center at Cincinnati Children’s, and his laboratory and clinical research program focuses on airway and epithelial biology, examining novel targets to treat cystic fibrosis.  His area of expertise includes developing agents to restore function to disease-causing mutations in the cystic fibrosis transmembrane conductance regulator (CFTR), which is the root cause of CF.  He also focuses on developing preclinical model systems and patient biomarkers to bridge these findings from the lab to the bedside.  Clancy has played international leadership roles in drug development, study design and execution and data analysis for new cystic fibrosis therapeutics, and recently served as the international lead investigator of two phase 2 studies of new CF treatments.  His translational research laboratory brings basic research laboratory personnel and clinical research coordinators together, and provides an environment for the training of students, medical professionals and research scientists in translational research.
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