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Our research focuses on the molecular and genetic signaling pathways involved in reproductive cancers. The causes of these diseases are not well understood and treatment options are limited. Using novel mouse models, we are attempting to uncover the signaling networks involved in the cancers’ development and maintenance. Understanding these networks could one day play a role in interrupting the growth of malignant cancers.
We also collaborate with the Dey lab to examine the signaling pathways involved in blastocyst implantation in pregnancy.
Our work on endometrial cancer focuses on PTEN and p53 genetic mutations.
We investigate the involvement of Cox-1, and the effects of its inhibitors, on ovarian cancer.
This longstanding collaboration with the Dey lab explores various factors influencing successful blastocyst implantation in pregnancy.
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