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The Rheumatic Disease Research Informatics Core provides biomedical informatics expertise and infrastructure to the P30-supported Cincinnati Rheumatic Diseases Core Center (CRDCC) Research Base at Cincinnati Children’s Research Foundation (CCRF) and collaborating centers. Research data management and bioinformatics analyses are essential components of rheumatology research programs at CCRF, especially as data streams from gene expression microarrays, flow cytometry and genotyping have increased. Investigators rely on easy, secure access to curated, accurate clinical and genomic data, as well as analysis tools. Access to informatics expertise through the Informatics Core enables the CRDCC Research Base to undertake large-scale, multi-institutional, data and processing-intensive research projects. Informatics Core staff contribute their own background and expertise, and they also facilitate access to the larger pool of informatics expertise at the institution, including the Division of Biomedical Informatics (BMI). The Informatics Core is the CRDCC Research Base’s gateway to state-of-the-art biomedical informatics support.
The principal functions of the Informatics Core are:
The availability of the unique resource of the Informatics Core is essential to enabling definitive genomic and clinical studies necessary to understand and define childhood rheumatic diseases.
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