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2012
Ercan A, Barnes MG, Hazen M, Tory H,
Henderson L, Dedeoglu F, Fuhlbrigge RC, Grom AA, Holm IA, Kellogg M, Kim
S, Adamczyk B, Rudd PM, Son MB, Sundel RP, Foell D, David N. Glass
DN, Thompson SD, and PA. Nigrovic. Multiple juvenile idiopathic arthritis
subtypes demonstrate pro-inflammatory IgG glycosylation. Arthritis Rheum; 64:3025-33. 2012.
De Benedetti F, Brunner HI,
Ruperto N, Kenwright, A, Ravelli A, Schneider, Woo P, Wouters C, Zemel, L,
Burgos-Vargos R, Dolezalova P, Grom AA, Wulffraat N, Zuber Z, Zulian F,
Lovell D and Martini A. Tocilizumab in systemic juvenile idiopathic arthritis:a randomized trial. New Engl J Med; 367:2385-95. 2012.
Ravelli A, Grom AA,
Behrens E, and RQ Cron. Macrophage Activation Syndrome as Part of SystemicJuvenile Idiopathic Arthritis: Diagnosis, Genetics, Pathophysiology, andTreatment.Genes & Immunity; 13:289-98. 2012.
Sikora KA, Fall N, Thornton S
and Grom AA. A Markedly Low-Level of Interferon-Induced Gene Expression
Distinguishes Active Systemic Juvenile Idiopathic Arthritis Synovium From other
JIA subtypes: Implications for Pathogenesis of Macrophage Activation Syndrome. Arthritis
Rheum; 64:3799-808. 2012.
Giannini EH, Ilowite NT,
Sandborg CI, Feldman BM, Grom AA, Schanberg LE, Wallace CA, Schneider R,
Kenney K, Gottlieb BS, Hashkes PJ, Imundo LF, Kimura Y, Lang BA, Miller ML,
Milojevic D, O'Neil KM, Punaro MG, Ruth NM, Singer NG, Vehe RK, Verbsky
J, Woodward A, and LS Zemel.Algorithm Development for Corticosteroid
Management in Systemic Juvenile Idiopathic Arthritis Trial Using Consensus
Methodology. Pediatric Rheumatology; 10:31. 2012.
Ruperto N, Brunner HI,
Quartier P, Constantin T, Wulfraat N, Horneff G, Brik R, McCann L, Nistala K,
Wouters C, Cimaz R, Ferrandiz MA, Flato B, Grom AA, Magnusson, Ozen S,
Abrams K, Kim D, Martini A, Lovell DJ. Canakinumab in systemic juvenilearthritis with active systemic features. New Engl J Med; 367:2396-406. 2012.
Grom
AA. Macrophage Activation Syndrome. In: Isenberg DA, Maddison PJ, Woo
P, Glass DN, Breedveld FC (eds) Oxford Textbook of Rheumatology, Oxford
University Press, Oxford, (in press). 2012.
2011
Mellins ED, Macubas C,
Grom AA. Pathogenesis of systemic juvenile idiopathic arthritis: someanswers, more questions.Nature Reviews Rheumatology ;7:416-26. 2011.
Sumegi J, Barnes MG, Lee S,
Villanueva J, Zhang K, Nestheide SV, Risma K, Grom AA, and AH Filipovich.
Gene Expression Profiling of peripheral blood mononuclear cells from patientswith untreated familial hemophagocytic lymphohistiocytosis. Blood;117:151-60. 2011.
Davi S, Consolaro A,
Guseinova D, Pistorio A, Ruperto N, Martini, Cron RQ, Ravelli A and MAS Study
Group (Behrens EM, Benseler S, Grom AA, Katsikas M, Lang B, Miettunen P,
Ozen S, Ramanan A, Russo R, Schneider R, Sterba G, Wouters C). An International Consensus Survey of Diagnostic Criteria for Macrophage ActivationSyndrome in Systemic Juvenile Idiopathic Arthritis. J Rheumatol;
38:764-768. 2011.
Flick MJ, Chauhan AK, Frederick M, Talmage KE, Kombrinck KW, Miller W, Mullins ES, Palumbo JS, Zheng X, Esmon NL, Esmon CT, Thornton S, Becker A, Pelc LA, Di Cera E, Wagner DD, Degen JL. The development of inflammatory joint disease is attenuated in mice expressing the anticoagulant prothrombin mutant W215A/E217A. Blood. 117(23):6326-37. Jun 9, 2011.
Grom AA and Jordan MB. In Nabel EG and Fox D. ACP Medicine. Section 6, Immunology/Allergy. Chapter 10. Disorders of Antigen-Presenting Cells. 2011.
2010
Barnes MG, Grom AA, Thompson SD, Griffin TA, Luyrink LK, Colbert, RA, David N, Glass DN. Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis. Arthritis Rheum. 2010.
Hinze CH, Fall N, Thornton S, Griffin TA, Thompson SD, Colbert RA, Glass DN, Michael G, Barnes BG, Grom AA. Immature cell populations and an erythropoiesis gene-expression signature in systemic juvenile idiopathic arthritis: implications for pathogenesis. Arthritis Res Ther. 2010.
Barnes BG, Grom AA, Griffin TA, Colbert RA, Thompson SD. Gene expression profiles from peripheral blood mononuclear cells are sensitive to short processing delays. Biopreservation and Biobanking. 2010.
2009
Parodi A, Davì S, Pringe AB, Pistorio A, Ruperto N, Magni-Manzoni S, MD, Miettunen P, Bader-Meunier B, Espada G, Sterba G, Ozen S, Wright D, Saad Magalhães C, Khubchandani R, Michels H, Woo P, Toro Gutiérrez CE, Guseinova D, Cortis E, Kristen Hayward, Wouters C, Grom AA, Vivarelli M, Fischer KA, Martini A, Ravelli A. Macrophage Activation Syndrome in Juvenile Systemic Lupus Erythematosus. Multinational multicenter study of 38 patients. Arthritis Rheum. 60:3388-99. 2009.
Barnes MG, Grom AA, Thompson SD, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, Aronow BJ, Pavlidis P, Hinze C, Thornton S, Griffin TA, Colbert CA, DN Glass. Gene Expression Signatures in new onset untreated juvenile idiopathic arthritis. Arthritis Rheum. 60:2102-12. 2009.
Griffin TA, Barnes MG, Ilowite NT, Olson JC, Sherry DD, Gottlieb BS, Aronow BJ, Pavlidis P, Hinze C, Thornton S, Thompson SD, Grom AA, Colbert CA, DN Glass. Gene Expression Signatures in Polyarticular Juvenile Idiopathic Arthritis Demonstrate Disease Heterogeneity and Offer a Molecular Classification of Disease Subsets. Arthritis Rheum. 60:2113-23. 2009.
2008
Zhang K, Biroscak J, Glass DN, Thompson S, Finkel T, Murray P, Binstadt B, Filipovich A, Grom AA. Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13D polymorphisms. Arthritis Rheum. x58:2892-6. 2008.
Hazen MM, Woodward AL, Hofman I, Degar BA, Grom AA, Filipovich AH, Binstadt BA. Mutations of the hemophagocytosis-associated gene UNC13D in a patient with systemic juvenile idiopathic arthritis. Arthritis Rheum. 58:567-70. 2008.
Other Significant Publications
Fall N, Barnes M, Thornton S, Luyrink L, Olson J, Ilowite NT, Gottlieb E, Griffin T, Sherry DD, Thompson S, Glass DN, Colbert RA, Grom AA. Gene expression profiling in peripheral blood from patients with untreated new-onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome. Arthritis Rheum. 56:3793-804. 2007.
Shishov M, Henrickson M, Burgos-Vargas R, Rubio-Perez NE, Baca V, Romero-Feregrino R, Solis-Vallejo, Huang B, Grom AA, Lovell DJ. Systemic features and early prognostic factors in Hispanic and non-Hispanic children from the United States and Mexico with systemic juvenile idiopathic arthritis. Clin Exp Rhematol. 25:567-70. 2007.
Bleesing J, Prada E, Siegel DM, Villanueva J, Olson J, Ilowite N, Brunner HI, Griffin T, Graham TB, Sherry DD, Passo MH, Filipovich A, Grom AA. The diagnostic significance of soluble CD163 and soluble interleukin-2 receptor alpha-chain in macrophage activation syndrome and untreated new-onset systemic juvenile idiopathic arthritis. Arthritis Rheum. 56:965-71. 2007.
Flick, MJ, La Jeunesse CM, Talmage KE, Witte DP, Palumbo JS, Pinkerton MD,Thornton S, Degen JL. Fibrin(ogen) exacerbates inflammatory joint disease through a mechanism linked to the integrin alphaMbeta2 binding motif. J Clin Invest. 117(11):3224-35. Nov, 2007.
Pasternak B, Grom AA, Yazigi N, Cohen M. Suppurative Peripheral Arthritis in Inflammatory Bowel Disease. J Pediatr Gastroenterology & Nutrition. 45;117-20. 2007.
Brunner HI, Mueller M, Rutherford C, Passo MH, Grom AA, Mishra J, Devarajan P. Urinary Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker of Nephritis in Childhood-onset Systemic Lupus Erythematosus. Arthritis Rheum. 54:2577-84. 2006.
Fall N, Bove KE, Stringer KF, Lovell DJ, Brunner HI, Weiss J, Higgins GC, Bowyer SL, Graham TB, Thornton S, Grom AA. Association between lack of angiogenic response in muscle tissue and high expression of angiostatic ELR-negative CXC chemokines in patients with juvenile dermatomyositis: possible link to vasculopathy. Arthritis Rheum. 52:3175-80. 2005.
Ramanan AV, Grom AA. Does systemic-onset juvenile idiopathic arthritis belong under juvenile idiopathic arthritis. Rheumatology (Oxford). 44:1350-3. 2005.
Herman LM, Pinkerton M, Jennings, Yang L, Grom AA, Sowders D, Kersten S, Witte D, Hirsch R, Thornton S. Angiopoietin-like-4 is a potential angiogenic mediator in arthritis. Clin Immunol. 115:93-101. 2005.
Villanueva J, Lee S, Giannini EH, Graham TB, Passo MH Filipovich AH, Grom AA. Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome. Arthritis Res Ther. 7:R30-37. 2005.
Barnes M, Aronow B, Luyrink L, Moroldo M, Pavlidis P, Passo MH, Grom AA, Hirsch R, Giannini EH, Colbert R, Glass DN, Thompson S. Gene expression in juvenile arthritis and spondyloarthropathy: pro-angiogenic ELR+ chemokine genes relate to course of arthritis. Rheumatology (Oxford). 43:973-9. 2004.
Thornton S, Sowders D, Aronow B, Witte DP, Brunner HI, Giannini EH, Hirsch R. DNA microarray analysis reveals novel gene expression profiles in collagen-induced arthritis. Clinical Immunology. 105:155-168. 2002.
