Rheumatology

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    Division Head

    A photo of Hermine Brunner.

    Hermine I. Brunner, MD, MSc Director, Division of Rheumatology

    is a pediatric rheumatologist with a special interest in clinical and translational research, focusing on pediatric lupus. Her research is focused on biomarker discovery for children with lupus and the testing of new medications for various pediatric rheumatic diseases. Dr. Brunner is also involved in trial design and provides statistical support at Cincinnati Children's and is pioneering the development of outcome measures and improving the quality of care for children with lupus and other pediatric rheumatic diseases.

    Visit the Brunner Lab.

    513-636-4676
    hermine.brunner@cchmc.org

    Hermine I. Brunner, MD, MSc

    Director, Division of Rheumatology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-4116

    Email: hermine.brunner@cchmc.org

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    Specialties

    Clinical Interests

    Health-related quality of life; outcome research; lupus

    Research Interests

    Economic analyses; HRQOL; measurement development; outcome research; lupus 

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    Biography

    Hermine Brunner, MD, MSc, is a pediatric rheumatologist with a special clinical and research interest in pediatric lupus. Her research is focused on biomarker discovery and the testing of new medications for lupus. She is also involved in trial design and provides statistical support at Cincinnati Children's. As head of the Lupus Center, she is involved in the conduction of the Lupus Clinic and the organization of Lupus Support Groups. She also pioneers the development of outcome measures and improving the quality of clinical of children with lupus and other rheumatic diseases.

    Education and Training

    MD: Ludwig Maximilan University, Munich, Germany, 1991.

    Residency: University of Chicago, 1997.

    Fellowship: University of Toronto & Cincinnati, 1999.

    MSc: Clinical Epidemiology: University of Toronto, 1999.

    Certification: Pediatrics 1997; Rheumatology 2002.

    Publications

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    Faculty

    A photo of Edward Gianni.

    Edward H. Giannini, MSc, DrPH

    serves as project director for numerous clinical trials, and has vested a considerable part of his research career in the methodological aspects of conducting clinical trials in children with rheumatic diseases. In 2011 he received the ‘American College of Rheumatology Distinguished Clinical Investigator Award’ from among its 15,000 members.

    513-636-7634
    edward.giannini@cchmc.org

    Edward H. Giannini, MSc, DrPH

    Academic Information

    Emeritus, UC Department of Pediatrics

    Phone: 513-636-7634

    Email: edward.giannini@cchmc.org

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    Publications

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    A photo of Alexei Grom.

    Alexei A. Grom, MD

    is a pediatric rheumatologist with a special interest in the pathways associated with the development of macrophage activation syndrome, a life-threatening complication of systemic juvenile idiopathic arthritis (SJIA). His work includes a strong translational component; along with studying the mechanisms behind these conditions, his lab is researching potential biomarkers that could facilitate early diagnosis and treatment.
    Visit the Grom-Thornton Lab.

    513-636-3339
    alexei.grom@cchmc.org

    Alexei A. Grom, MD

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-3339

    Fax: 513-636-3328

    Email: alexei.grom@cchmc.org

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    Specialties

    Biography

    The research of Alexei Grom, MD, has mainly involved two translational projects focused on two autoimmune diseases – systemic juvenile rheumatoid arthritis and juvenile dermatomyositis. In both projects, recent advances of cellular immunology are applied to these diseases to promote better understanding of their pathogenesis and treatment.

    Systemic onset juvenile rheumatoid arthritis and an associated condition known as macrophage activation syndrome are severe and often devastating illnesses. The pathological mechanisms are not known but Dr. Alexei Grom has focused his research on NK and cytotoxic cell function in this disease. The rationale for this approach has been based on the strong clinical similarities between MAS and the better understood autosomal recessive disorder familial hemophagocytic lymphohistiocytosis, in which the uncontrolled proliferation of T cells and macrophages has been recently associated with decreased NK cell and cytotoxic cell functions secondary to mutations in the gene encoding perforin. Recent observations suggest as in FHLH, MAS patients also have profoundly depressed NK function. Moreover, a large subgroup of systemic JRA patients has very similar immunologic abnormalities. Combined with the evidence of the immunoregulatory role of NK cells in many immune responses, this suggests that NK dysfunction is relevant to the pathogenesis of MAS. New directions have thus been established for research in this poorly understood disease.

    Juvenile dermatomyositis is a chronic inflammatory condition involving primarily muscles and skin. The most characteristic feature of JDM is vascular damage associated with the capillary necrosis that eventually leads to capillary loss and tissue ischemia. The project is based on the hypothesis that capillary loss in this condition may be caused by angiostatic chemokines that are prominent in the inflammatory response in the affected muscles.

    Education and Training

    MD: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1986. 

    Residency: Leningrad (St. Petersburg) Medical Institute, Russia, 1988; Children's Hospital Medical Center, Cincinnati, Ohio, 1998. 

    Fellowship: Leningrad (St. Petersburg) Pediatric Medical Institute, Russia, 1991; Children's Hospital Medical Center, Cincinnati, Ohio, 1995. 

    Certification: Pediatrics, 1999.

    Publications

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    A photo of Michael Henrickson.

    Michael Henrickson, MD, MPH Clinical Director, Division of Rheumatology

    focuses on health policy development to improve national pediatric rheumatology workforce capacity. Strategies include creative policy solutions for current workforce challenges, developing telemedicine for pediatric rheumatology outreach to underserved regions, and establishing national benchmarks for clinical productivity. His second research interest is the development of global health initiatives to address the epidemiologic shift in developing countries to chronic conditions, including pediatric rheumatic diseases.

    513-636-7686
    michael.henrickson@cchmc.org

    Michael Henrickson, MD, MPH

    Clinical Director, Division of Rheumatology

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-7686

    Email: michael.henrickson@cchmc.org

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    Specialties

    Health policy, global health, neuropsychiatric-SLE, periodic fever syndromes, systemic JIA, culturally appropriate care, quality measures.

    Education and Training

    BA: Emory University, Atlanta, GA, 1980.

    MD: Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA, 1984.

    MPH: College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, 2009.

    Residency: Tripler Army Medical Center, Honolulu, HI, 1984-87.

    Fellowship: Children’s Hospital Medical Center, Cincinnati, OH, 1991-94.

    Certification: American Board of Pediatrics: General Pediatrics, 1988 (recertified 2004). Pediatric Rheumatology, 1994 (recertified 2008). National Board of Public Health Examiners, 2009.   

    Publications

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    A photo of Jennifer Huggins.

    Jennifer L. Huggins, MD Fellowship Program Director, Division of Rheumatology

    513-803-0649
    jennifer.huggins@cchmc.org

    Jennifer L. Huggins, MD

    Fellowship Program Director, Division of Rheumatology

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-0649

    Email: jennifer.huggins@cchmc.org

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    Education and Training

    MD: University of Kansas Medical School, Kansas City, Kansas 

    Publications

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    A photo of Daniel Lovell.

    Daniel J. Lovell, MD, MPH Associate Director, Division of Rheumatology

    focuses on the performance of interventional clinical trials in children with juvenile idiopathic arthritis (JIA) and other rheumatic diseases. He has served as the PI for >30 multicenter, interventional trials in JIA. Dr. Lovell is also involved in the development and validation of outcome measures and clinical response definitions for JIA, JDM and childhood onset systemic lupus erythematosus (SLE).

    513-636-4676
    daniel.lovell@cchmc.org

    Daniel J. Lovell, MD, MPH

    Associate Director, Division of Rheumatology

    Academic Information

    Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-5990

    Email: daniel.lovell@cchmc.org

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    Specialties

    Clinical Interests

    Diagnostic evaluation and ongoing care of children with all pediatric onset rheumatic diseases

    Research Interests

    Performance of clinical trials in children with rheumatic diseases; clinical trials methodology; mentoring of junior faculty

    Education and Training

    MD: University of Kansas, Kansas City, Kan., 1978. 

    MPH: University of Texas School of Public Health, Houston, Texas, 1982. 

    Residency: Children's Mercy Hospital, Kansas City, Kan. 

    Fellowship: Baylor College of Medicine, Houston, Texas. 

    Certification: Pediatrics, 1984; Pediatric Rheumatology, 1992.

    Publications

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    Rina Mina, MD

    Academic Information

    Assistant Professor, OtherUC Department of Internal Medicine

    Assistant Professor, Assistant Professor, UC Department of Immunology

    Phone: 513-429-9091

    Email: rina.mina@cchmc.org

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    Education and Training

    MD: University of the Philippines, Manila, Philippines, 1997.

    Residency: Internal Medicine Pediatrics, State University of New York-Downstate Medical Center, Brooklyn, NY, 2003. 

    Certificate Program: Medical Informatics, State University of New York-Downstate Medical Center, Brooklyn, NY, 2002. 

    Fellowship: Rheumatology (Combined Pediatric and Adult Rheumatology), Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 2012.

    MS: Clinical and Translational Research Epidemiology, University of Cincinnati, Cincinnati, OH, 2011.

    Publications

    A photo of Esi Morgan DeWitt.

    Esi Morgan DeWitt, MD, MSCE

    focuses on the development and validation of patient reported outcomes measures using modern psychometric approaches, including item response theory, for improved health assessment in children. A second major research focus concerns improving clinical outcomes of patients with juvenile idiopathic arthritis through the science of quality improvement.

    513-636-4676
    esi.morgan-dewitt@cchmc.org

    Esi Morgan DeWitt, MD, MSCE

    Academic Information

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Email: esi.morgan-dewitt@cchmc.org

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    Specialties

    Clinical Interests

    Childhood rheumatic diseases; juvenile idiopathic arthritis; juvenile dermatomyositis; sarcoidosis

    Research Interests

    Patient reported outcomes measure development; quality Improvement; health services research; economic evaluations; comparative effectiveness

    Biography

    Esi Morgan DeWitt, MD, MSCE, is a pediatric rheumatologist and researcher. Clinical care spans the childhood rheumatic diseases, with focus on juvenile idiopathic arthritis (JIA) and juvenile dermatomyositis.

    Her research training and experience includes epidemiology and health services research, in addition to specialization in quality improvement methods and application to improve health care delivery. Dr. Morgan DeWitt leads a research project to develop new measures to assess pain in children and youth, as well as to validate measures of health related quality of life in children with juvenile idiopathic arthritis or chronic pain as part of a national network of investigators.

    Dr. Morgan DeWitt is a leader in a multi-center quality improvement network to improve the outcome of care in children with JIA, the Pediatric-Rheumatology Care and Outcomes Improvement Network. Additionally, she has served on expert panels in development of JIA treatment recommendations and measures of quality of care in treatment of JIA.

    Education and Training

    MD: Washington University School of Medicine, St. Louis, MO, 1999.

    Residency: Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, 2002.

    Fellowship: Rheumatology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2005.

    MSCE: University of Pennsylvania, Center for Clinical Epidemiology & Biostatistics, Philadelphia, PA, 2005.

    Certification: Pediatrics, 2002; Pediatric Rheumatology, 2006.

    Publications

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    Thornton-Sherry.

    Sherry L. Thornton, PhD

    her research focuses on finding and functionally evaluating targets for the treatment of rheumatic disease, with a particular interest in the role of angiogenesis in human arthritis and animal models of arthritis. A second interest is the use of reagents to label inflammatory cells for visualization during arthritis as a potential clinical tool, and for evaluation of cell types during the course of disease in animal models.
    Visit the Grom/Thornton Lab.

    513-636-1318
    sherry.thornton@cchmc.org

    Sherry L. Thornton, PhD

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-1318

    Fax: 513-636-3328

    Email: sherry.thornton@cchmc.org

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    Specialties

    Evaluating targets for the treatment of rheumatic disease; angiogenesis; animal models of arthritis

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    Education and Training

    BS: Ball State University, Muncie, Indiana.

    PhD: University of Cincinnati, College of Medicine, Cincinnati, OH.

    Postdoctoral Research Fellow: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

    Publications

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    A photo of Tracy Ting.

    Tracy V. Ting, MD, MSc, RhMSUS

    Academic Information

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4676

    Fax: 513-636-5568

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    Specialties

    Clinical

    Fibromyalgia; joint hypermobility; juvenile idiopathic arthritis (JIA); systemic lupus erythematosus (SLE)

    Education and Training

    MD: West Virginia University, Morgantown, WV, 2002.

    Residency: Cleveland Clinic, Cleveland, OH, 2005.

    Certification: Pediatrics, 2005; Pediatric Rheumatology, 2011.

    Publications

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