Center for Acute Care Nephrology

  • Meet the Team

    The Center for Acute Care Nephrology, part of the Nephrology and Hypertension Division at Cincinnati Children's, is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.

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    Director

    A photo of Stuart L. Goldstein.

    Stuart L. Goldstein, MD
    Director, Center for Acute Care Nephrology

    513-803-3295

    stuart.goldstein@cchmc.org

    Stuart L. Goldstein, MD

    Director, Center for Acute Care Nephrology

    Professor, UC Department of Pediatrics

    Phone: 513-803-3295

    Fax: 513-636-6407

    Email: stuart.goldstein@cchmc.org

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    Specialties

    Clinical Interests

    Acute kidney injury; continuous renal replacement therapy; end-stage renal disease; health-related quality of life

    Research Interests

    Acute kidney injury epidemiology and biomarkers; health-related quality of life in ESRD; cardiovascular complications and inflammation in ESRD

    Biography

    Stuart L. Goldstein, MD has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000.  Dr.  Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population.  Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 39 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI. 

    Dr. Goldstein has led initial efforts to develop a standardized definition for pediatric AKI, assess novel AKI biomarkers in heterogeneous populations, and conceiving and validating stratification tools to identify patients at risk for AKI.  Building up these findings, Dr. Goldstein embarked on establishing the ppAKI-RG consortium to focus on multi-centered research studies that are dedicated to understanding and treating AKI in pediatric patients.  Currently, the ppAKI-RG has initiated three major, and unprecedented, national and international studies (AWARE, NINJA and DIRECT) to reduce AKI and improve patient outcomes.  Dr. Goldstein is also a recognized educator; he has developed the only pediatric specific Acute Care Nephrology sub-specialty fellowship with graduates who are now leaders in the field of pediatric AKI.

    Education and Training

    MD: Columbia College of Physicians and Surgeons, New York, NY, 1990.

    Residency: Baylor College of Medicine, Houston, TX.

    Fellowship: Pediatric Nephrology, Children's Hospital, Boston, MA.

    Publications

    View PubMed Publications

    Grants

    PlasmaLyte Gastroenteritis Study. Principal Investigator. Baxter Healthcare. Nov 2010 - Oct 2011.

    Inflammation, malnutrition and cardiac calcification in pediatric ESRD patients receiving dialysis- a comparison of hemodialysis vs. peritoneal dialysis. Principal Investigator. Baxter Healthcare. Dec 2010 - Dec 2011.

    Optimize Fluid Dosing in Critically Ill Children with Acute Kidney Injury. Principal Investigator. Casey Lee Ball Foundation. Jan 2011 – Dec 2011.

    Use of NGAL to Optimize Fluid Dosing, CRRT Initiation and Discontinuation in Critically Ill Children with Acute Kidney Injury. Principal Investigator. Casey Lee Ball Foundation. Feb 2011 - Jan 2012.

    Evaluation of cystatin C and Urine Proteins as Early Biomarkers of AKI in Children Treated with Nephrotoxic Medication. Principal Investigator. The Research Institute of McGill University Health Centre. Jun 2011 – Jun 2012.

    Center for Acute Care Nephrology Fellowship. Fellowship Director. Funded by Gambra Renal Products.  Jan 2011 - Jan 2013.

    Inflammation, malnutrition and cardiac calcification in pediatric ESRD patients receiving dialysis. Principal Investigator.  Casey Lee Ball Foundation. Jan 2010 - Dec 2020.

    Faculty

    A photo of Raj Basu.

    Raj K. Basu, MD
    Co-Director, Center for Acute Care Nephrology

    513-636-4259

    rajit.basu@cchmc.org

    Raj K. Basu, MD

    Co-Director, Center for Acute Care Nephrology

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4259

    Fax: 513-636-4267

    Email: rajit.basu@cchmc.org

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    Specialties

    Pediatric critical care; acute kidney injury; ethics/end-of-life care

    Biography

    Dr. Basu arrived at Cincinnati Children's after completing his residency and fellowship training at Children’s Memorial Hospital in Chicago. The focus of his research efforts thus far have been in increasing the appreciation for the impact of acute kidney injury (AKI) on critical illness. In addition to his research and publication efforts, Dr. Basu has been actively involved in the fellowship program coordinating numerous lectures, an ethics curriculum, and mentoring residents/fellows. He also currently sits on the hospital action committees dedicated to improving the care of status asthmaticus and status epilepticus.

    Education and Training

    MD: Indiana University, Indianapolis, IN 2003

    Residency: Pediatrics, Northwestern University Children’s Memorial Hospital, Chicago, IL, 2003-2006

    Fellowship: Pediatric Critical Care, Northwestern University Children’s Memorial Hospital, Chicago, IL, 2006-2009

    Certifications: Pediatrics, 2006; Critical Care, 2010

    Publications

    View PubMed Publications
    A photo of Michael Bennett.

    Michael R. Bennett, PhD
    Director, Biomarker Laboratory

    513-636-8349

    michael.bennett@cchmc.org

    Michael R. Bennett, PhD

    Director, Biomarker Laboratory

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-8349

    Email: michael.bennett@cchmc.org

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    Specialties

    Diagnostic markers for pediatric diseases; acute kidney injury; nephrotic syndrome, lupus nephritis; focal segmental glomerulosclerosis; mechanisms of neurologic disease

    Education and Training

    Research Fellowship: Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    PhD: University of Cincinnati College of Medicine, Cincinnati, OH, 2004.

    BA: Thomas More College, Crestview Hills, KY, 1997.

    Publications

    View PubMed Publications

    A photo of David Cooper.

    David S. Cooper, MD, MPH
    Director, Cardiac Extracorporeal Life Support Program

    513-803-1801

    david.cooper@cchmc.org

    David S. Cooper, MD, MPH

    Director, Cardiac Extracorporeal Life Support Program

    Associate Director, Cardiovascular Intensive Care Unit

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-1801

    Email: david.cooper@cchmc.org

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    Specialties

    Cardiac critical care; extracorporeal life support

    Education and Training

    MD: University of South Florida College of Medicine, Tampa, Florida, 1996.

    MPH: University of South Florida College of Public Health, Tampa, Florida, 1999.

    Residency: All Children’s Hospital, University of South Florida, St. Petersburg, FL.

    Fellowships: Cardiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; Critical Care, Children’s Medical Center Dallas, UT Southwestern, Dallas, Texas.

    Certifications: American Board of Pediatrics; American Board of Pediatrics, Sub-board of Pediatric Cardiology; American Board of Pediatrics, Sub-board of Pediatric Critical Care.

    Publications

    View PubMed Publications
    A photo of Prasad Devarajan.

    Prasad Devarajan, MD
    Director, Division of Nephrology and Hypertension

    513-636-4531

    prasad.devarajan@cchmc.org

    Prasad Devarajan, MD

    Director, Division of Nephrology and Hypertension

    Medical Director, Stone Center

    Director, Nephrology and Hypertension Clinical Laboratory

    Louise M. Williams Endowed Chair

    Professor, UC Department of Pediatrics

    Phone: 513-636-4531

    Fax: 513-636-7407

    Email: prasad.devarajan@cchmc.org

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    Specialties

    Clinical specialties: Acute kidney injury, nephrotic syndrome, kidney stones

    Visit the Devarajan Lab.

    Education and Training

    Premedical Studies: Bombay University, India, 1979. 

    MD: Bombay University, India, 1985.

    Publications

    View PubMed Publications

    A photo of John Jefferies.

    John Lynn Jefferies, MD, MPH, FAAP, FACC
    Director, Advanced Heart Failure and Cardiomyopathy

    513-803-1675

    john.jefferies@cchmc.org

    John L. Jefferies, MD, MPH, FAAP, FACC

    Director, Advanced Heart Failure and Cardiomyopathy

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-1675

    Email: john.jefferies@cchmc.org

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    Specialties

    Heritable causes of vascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity. 

    Biography

    Dr. Jefferies, an associate professor of pediatric cardiology and adult cardiovascular diseases, is the director of Advanced Heart Failure / Cardiomyopathy within The Heart Institute at Cincinnati Children's Hospital Medical Center. 

    He completed his combined pediatric and adult cardiology training at the Baylor College of Medicine in Houston, Texas at the Texas Children's Hospital and the Texas Heart Institute. He has authored or co-authored over 100 peer-reviewed manuscripts and book chapters on cardiomyopathy, cardiovascular genetics, and adults with congenital heart disease. 

    His current research interests include heritable causes of vascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity. 

    He is on the editorial board of the Texas Heart Institute Journal and is an active member of numerous professional organization including the Heart Failure Society of America, the American College of Cardiology and the American Heart Association.

    Education and Training

    BS: University of Tennessee, Knoxville, TN, 1992.

    MD: University of Tennessee, Knoxville, TN, 1996.

    Residency: University of Kentucky, Lexington, KY, 2000.

    MPH: University of Kentucky, Lexington, KY, 2001 Fellowship: Baylor College of Medicine, Houston, TX, 2006.

    Certification: Internal Medicine, 2000; Pediatrics, 2001

    Publications

    View PubMed Publications
    A photo of David Nelson, MD.

    David P. Nelson, MD, PhD
    Director, Cardiac Intensive Care

    513-803-1801

    david.nelson@cchmc.org

    David P. Nelson, MD, PhD

    Director, Cardiac Intensive Care

    Professor, UC Department of Pediatrics

    Phone: 513-803-1801

    Fax: 513-803-1821

    Email: david.nelson@cchmc.org

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    Specialties

    Clinical Interests

    Neurodevelopmental outcomes; family-centered care; cardiopulmonary interactions; physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure; cardio-renal syndrome; end of life care

    Research Interests

    Quality of life and neurodevelopmental outcomes in children with acquired and congenital heart disease; etiology of adrenal dysfunction in cardiac intensive care; inflammatory organ system injury after congenital heart surgery

    Biography

    David P. Nelson, MD, PhD, completed his Fellowship in Pediatric Critical Care at Harvard University, Boston Children’s Hospital. He served as the co-director of Cardiac Intensive Care at Cincinnati Children’s Hospital Medical Center (CCHMC) from July 1996 to August 2005. In September of 2005, Dr. Nelson served as the director of Cardiac Intensive Care at Texas Children’s Hospital for four years before rejoining CCHMC as the director of Cardiac Intensive Care in 2009.

    Dr. Nelson’s clinical interests include neurodevelopmental outcomes in children with acquired and congenital disease; family-centered care; cardiopulmonary interactions and the physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure in children; cardio-renal syndrome and end of life care.

    His research focuses on quality of life and neurodevelopmental outcomes in children with acquired and congenital heart disease; etiology of adrenal dysfunction in cardiac intensive care; inflammatory organ system injury and congenital heart surgery.

    Education and Training

    PhD: University of Chicago, 1987

    MD: University of Chicago Pritzker School of Medicine, 1989.

    Residency: University of Washington-Children’s Hospital Medical Center, 1989-1992.

    Fellowship: Harvard University, Boston Children’s Hospital, 1992-1994.

    Certification:  Pediatrics, 1992; Pediatric Cardiology, 1994; Pediatric Critical Care, 1998.

    Publications

    View PubMed Publications

    Staff

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    Ahmad Kaddourah, MD
    Clinical Fellow, Division of Nephrology and Hypertension

    513-636-4531

    ahmad.kaddourah@cchmc.org