Cancer and Blood Diseases Institute

  • Advanced Cancer Therapies Center

    Through the Advanced Cancer Therapies Center at Cincinnati Children’s Hospital Medical Center, highly trained oncologists subspecializing in specific childhood cancers treat patients with high risk and relapsed disease using the most advanced therapies available.

    The faculty of the Advanced Cancer Therapies Center are developing and refining the next generation of innovative treatments through the robust laboratory and translational research programs within the Cancer and Blood Diseases Institute at Cincinnati Children’s and through their leadership in national pediatric cancer research consortia.

    Center Highlights

    • Cincinnati Children’s faculty are national leaders in the National Cancer Institute (NCI) Pediatric Phase I Consortium, the Children’s Oncology Group (COG), the New Approaches to Neuroblastoma Consortium (NANT), the Collaborative Ependymoma Research Network (CERN), the Neurofibromatosis Clinical Consortium, and other leading pediatric cancer clinical research consortia.
    • Close collaborations among faculty in the Division of Oncology, the Division of Bone Marrow Transplantation and Immune Deficiency, and the Division of Experimental Hematology and Cancer Biology – as well as other Divisions and programs across Cincinnati Children’s – allow the rapid development of novel therapies such as oncolytic viruses, therapeutic antibodies, and novel signal transduction inhibitors.
    • A pediatric cancer drug discovery program uses an industry-grade compound library to screen for potential new drugs to fight pediatric cancers, which are then refined and tested in our laboratories.
    • A new Radiobiologics Therapy Program is developing new treatments for high risk neuroblastoma and leukemia / lymphoma.
    • New laboratory initiatives are developing the capability to rapidly analyze patient tumors for specific genetic mutations to help direct patients to the most appropriate novel targeted drugs.

    For more information about the Advanced Cancer Therapies Center, contact:

    John Perentesis, MD, FAAP
    Director of Oncology Division
    john.perentesis@cchmc.org
    513-636-4266

 
 
 
 
  • Support our Care and Research

    Please support our research efforts.

    The Cincinnati Children’s Cancer and Blood Diseases Institute is one of the largest clinical care and research centers for pediatric cancers and blood diseases in the United States. We need your help to continue our world-class care and research.

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  • Cancer Centers and Programs

    Learn more about the other centers and programs that the Cancer and Blood Diseases Institute offers for children and young adults with various forms of cancer, including brain and spinal tumors, neuroblastomas and leukemia / lymphoma.

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