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Cancer and Blood Diseases Institute

Cancer and Blood Diseases Institute

 
 

  • Tests Offered

    The Diagnostic Immunology Laboratories offer a large menu of specialized tests. See a complete list below. In addition, we also provide a complete assay description for each test. 

    Click on the tests below for more information.

  • Specialized Tests

    Show All

    + ALPS panel

    Test Name: ALPS panel
    Method: flow cytometry
    Indication: Autoimmune Lymphoproliferative Syndrome

    + Antigen Stimulation

    Test Name: Antigen Stimulation
    Method: thymidine uptake
    Indication: Immune Deficiencies, post BMT monitoring

    + Apoptosis (Fas-mediated)

    Test Name: Apoptosis (Fas-mediated) 
    Method: culture and flow cytometry
    Indication: Autoimmune Lymphoproliferative Syndrome, primary immune deficiencies

    + B-Cell Panel

    Test Name: B-Cell Panel
    Method: flow cytometry
    Indication: Disorders of B cell development and differentiation

    + BAFF, plasma levels

    Test Name: BAFF, plasma levels 
    Method: ELISA
    Indication: Autoimmune disorders, and disorders of B-cell survival and maturation, as well as B-cell reconstitution post B-cell depleting therapy

    + CD40L (CD154) / ICOS

    Test Name: CD40L (CD154)
    Method: flow cytometry
    Indication: Hyper IgM Syndrome

    + CD45RA/CD45RO

    Test Name: CD45RA/CD45RO 
    Method: flow cytometry
    Indication: Immune Deficiencies, DiGeorge Syndrome, post BMT monitoring

    + CD59 (PNH Screen)

    Test Name: CD59 (PNH Screen)
    Method: flow cytometry
    Indication: Paroxysmal Nocturnal Hemoglobinuria

    + CD52 Expression

    Test Name: CD52 Expression 
    Method: flow cytometry
    Indication: Campath Treatment Monitor

    + CD64 (Leuko64)

    Test Name: CD64 (Leuko64) 
    Method: flow cytometry
    Indication: Sepsis, Inflammatory conditions

    + CD107a Mobilization

    Test Name: CD107a Mobilization
    Method: culture and flow cytometry
    Indication:  HLH, suspected MUNC13-4 mutations

    + CD127/CD132

    Test Name: CD127/CD132
    Method: flow cytometry
    Indication: Severe Combined Immunodeficiency

    + CTL Function

    Test Name: CTL Function
    Method: chromium release
    Indication: Immune Deficiencies, XLP, HLH, post BMT monitoring

    + Cytokines, Intracellular

    Test Name: Cytokines, Intracellular
    Method: flow cytometry
    Indication: Autoinflammatory conditions, periodic fever, LCH

    + Cytokines, Plasma or CSF

    Test Name: Cytokines, Plasma or CSF
    Method: MultiPlex
    Indication: Autoinflammatory conditions, periodic fever, LCH


    + EBV Immortalized Cell Line

    Test Name: EBV Immortalized Cell Line
    Method: cell culture
    Indication: Pre-transplant DNA source

    + Foxp3 Expression

    Test Name: Foxp3 Expression
    Method: flow cytometry
    Indication: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX)

    + iNKT (Invariant natural killer T cells)

    Test Name: iNKT (Invariant natural killer T cells)
    Method: flow cytometry
    Indication: X-linked Lymphoproliferative Disease

    + Lymphocyte Activation Markers

    Test Name: Lymphocyte Activation Markers
    Method: flow cytometry
    Indication: Disorders of Immune Activation, post BMT monitoring (GVHD)

    + Lymphocyte Subset Analysis

    Test Name: Lymphocyte Subset Analysis 
    Method: flow cytometry
    Indication: Immune Deficiencies

    + MHC Class I & II Expression

    Test Name: MHC Class I & II Expression
    Method: flow cytometry
    Indication: Bare Lymphocyte Syndrome, SCID

    + Mitogen Stimulation

    Test Name: Mitogen Stimulation
    Method: thymidine uptake
    Indication: Immune Deficiencies

    + Neopterin (plasma and CSF)

    Test Name: Neopterin
    Method: ELISA
    Indication: Allograft recipient complications, malignant diseases, autoimmune diseases, monitoring immunostimulatory therapy 

    + Neutrophil Adhesion Markers

    Test Name: Neutrophil Adhesion Markers
    Method: flow cytometry (CD18 and CD11b)
    Indication: Leukocyte Adhesion Deficiency

    + Neutrophil Chemotaxis

    Test Name: Neutrophil Chemotaxis
    Method: under agarose
    Indication: Neutrophil Function Disorders

    + Neutrophil Oxidative Burst

    Test Name: Neutrophil Oxidative Burst
    Method: flow cytometry (DHR)
    Indication: Chronic Granulomatous Disease

    + Neutrophil Phagocytosis and Killing

    Test Name: Neutrophil Phagocytosis and Killing
    Method: acridine orange microbicidal
    Indication: Neutrophil Function Disorders

    + NK Function

    Test Name: NK Function
    Method: chromium release
    Indication: Hemophagocytic Lymphohistiocytosis, XLP

    + Perforin/Granzyme B

    Test Name: Perforin/Granzyme B 
    Method: flow cytometry
    Indication: Hemophagocytic Lymphohistiocytosis

    + pSTAT5

    Test Name: pSTAT5
    Method: flow cytometry
    Indication: X-SCID, JAK3 deficiency

    + SAP (XLP1)

    Test Name: SAP (XLP1)
    Method: flow cytometry
    Indication: X-linked Lymphoproliferative Disease

    + Soluble CD163

    Test Name: Soluble CD163
    Method: ELISA
    Indication: Infectious, Inflammatory and Myeloproliferative Diseases

    + Soluble IL-2R

    Test Name: Soluble IL-2R
    Method: chemiluminescent immunoassay
    Indication: Autoimmune and Infectious Disorders, Transplantation Rejection, HLH

    + TCR alpha/beta gamma/delta

    Test Name: TCR alpha/beta gamma/delta
    Method: flow cytometry
    Indication: Immune Deficiencies, post BMT monitoring

    + TCR V beta Repetoire/Clonogram

    Test Name: TCR V-beta
    Method: flow cytometry
    Indication: Suspected Clonal Expansion of T cells, maternal GvHD, SCID, T ALL

    + Wiskott Aldrich Syndrome Protein (WASP)

    Test Name: WAS Protein Expression
    Method: flow cytometry
    Indication: Wiskott Aldrich Syndrome

    + Wiskott Aldrich Syndrome Protein (WASP) Transplant Monitor

    Test Name: WASP Transplant Monitor
    Method: flow cytometry
    Indication: Wiskott Aldrich Syndrome, post-transplant monitor 

    + XIAP (XLP2) Protein Expression

    Test Name: XIAP (XLP2) Protein Expression
    Method: flow cytometry
    Indication: X-linked Lymphoproliferative Disease  

    + ZAP-70

    Test Name: ZAP-70
    Method: flow cytometry
    Indication: SCID

 
  • Search all tests offered by the Clinical Laboratories at Cincinnati Children's.

    Search all tests offered by the Clinical Laboratories at Cincinnati Children's.

    Search for a Test

    Search all tests offered by the Clinical Laboratories at Cincinnati Children's.

    Search all tests offered by the Clinical Laboratories at Cincinnati Children's.

  • Test Requisition Form

    To request testing, download the most current version of our Test Requisition Form in portable document format (pdf).

    Read more
 
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