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The Cancer and Blood Diseases Institute is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.
Our divisions are led by the following:
Oncology: John Perentesis, DirectorHematology: Russell Ware, DirectorExperimental Hematology and Cancer Biology: Yi Zheng, DirectorBone Marrow Transplantation / Immune Deficiency: Stella Davies, Director
Stefanie W. Benoit, MD, MPH Staff Physician, Bone Marrow Transplantation and Immune Deficiency 513-636-4214 email@example.com
Staff Physician, Bone Marrow Transplantation and Immune Deficiency
MD: Case Western Reserve University, Cleveland, OH, 2010.
Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.
Jacob (Jack) J.H. Bleesing, MD, PhD 513-636-4266 firstname.lastname@example.org
Professor, UC Department of Pediatrics
Immunobiology; translational research; immunologic methods development
Jodele S, Bleesing JJ, Mehta PA, Filipovich AH, Laskin BL, Goebel J, Pinkard SL, Davies SM. Successful early intervention for hyperacute transplant-associated thrombotic microangiopathy following pediatric hematopoietic stem cell transplantation. Pediatr Transplant. 2010 Nov 5. Eckrich MJ, Yang E, Domm J, Ho R, Calder C, Manes B, Bleesing J, Frangoul H. A Unique Clinical Presentation of X-Linked Lymphoproliferative Syndrome With a Novel Mutation in SH2D1A and Review of the Literature. J Pediatr Hematol Oncol. 2010 Oct 21. Marsh RA, Bleesing JJ, Filipovich AH. Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiency. J Immunol Methods. 2010 Oct 31;362(1-2):1-9. Marsh RA, Villanueva J, Kim MO, Zhang K, Marmer D, Risma KA, Jordan MB, Bleesing JJ, Filipovich AH. Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations. Clin Immunol. 2009 Jul;132(1):116-23.
Marsh RA, Villanueva J, Zhang K, Snow AL, Su HC, Madden L, Mody R, Kitchen B, Marmer D, Jordan MB, Risma KA, Filipovich AH, Bleesing JJ. A rapid flow cytometric screening test for X-linked lymphoproliferative disease due to XIAP deficiency. Cytometry B Clin Cytom. 2009 Sep;76(5):334-44. Hansen MD, Filipovich AH, Davies SM, Mehta P, Bleesing J, Jodele S, Hayashi R, Barnes Y, Shenoy S. Allogeneic hematopoietic cell transplantation (HCT) in Hurler's syndrome using a reduced intensity preparative regimen. Bone Marrow Transplant. 2008 Feb;41(4):349-53. Bhatla D, Davies SM, Shenoy S, Harris RE, Crockett M, Shoultz L, Smolarek T, Bleesing J, Hansen M, Jodele S, Jordan M, Filipovich AH, Mehta PA. Reduced-intensity conditioning is effective and safe for transplantation of patients with Shwachman-Diamond syndrome. Bone Marrow Transplant. 2008 Aug;42(3):159-65.
Zhang K, Johnson JA, Biroschak J, Villanueva J, Lee SM, Bleesing JJ, Risma KA, Wenstrup RJ, Filipovich AH. Familial haemophagocytic lymphohistiocytosis in patients who are heterozygous for the A91V perforin variation is often associated with other genetic defects. Int J Immunogenet. 2007 Aug;34(4):231-3.
JJH Bleesing. Assays for B Cell and Germinal Center Development (unit 7.34). In Current Protocols in Immunology. JE Coligan, BE Bierer, DH Margulies, EM Shevach, W Strober (eds.). Hoboken: John Wiley & Sons, 2004. JJH Bleesing, TA Fleisher, JM Puck. Autoimmune lymphoproliferative syndrome (ALPS). In Immunologic Disorders in Infants and Children. 5th ed. ER Stiehm, HD Ochs, JA Winkelstein (eds). Philadelphia, PA: WB Saunders, 2004.
Sharat Chandra, MBBS, MD, MRCPCH 513-636-4266 email@example.com
Assistant Professor, UC Department of Pediatrics
Blood and marrow transplant, malignant and primary immune deficiency disorders.
MBBS: Andhra Medical College, University of Health Sciences, Visakhapatnam, India.
Residency: Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 1998-2001; University Hospitals of Leicester, South Warwickshire Hospitals NHS, United Kingdom, 2003-2006; University of South Alabama, 2006-2009.
Fellowship: Pediatric Hematology-Oncology, Cincinnati Children’s Hospital Medical Center, 2009-2012.
Certification: MD (Pediatrics), 2001; Royal College of Pediatrics and Child Health (MRCPCH), 2006; Board Certified in General Pediatrics by the American Board of Pediatrics, 2009; Board Certified in Pediatric Hematology-Oncology by the American Board of Pediatrics, 2013.
Singh M, Mathew JL, Chandra S, Katariya S, Kumar L. Randomized controlled trial of intrapleural streptokinase in empyema thoracis in children. Acta Paediatrica. 2004 Nov; 93(11):1443-5.
Chandra S, Haines H, Michie C, Maheshwari A. Developmental Defects in Neutrophils from Preterm Infants. NeoReviews. 2007;8: e368-e376.
Mancao M, Imran H, Chandra S, Estrada B, Figarola M, Sosnowski J, Vidal R. Eastern equine encephalitis virus infection and hemophagocytic lymphohistiocytosis in a 5-month old infant. Pediatr Infect Dis J. 2009 Jun;28(6):543-5.
Pan D, Kalfa TA, Wang D, Risinger M, Crable S, Ottlinger A, Chandra S, Mount DB, Hübner CA, Franco RS, Joiner CH. K-Cl Cotransporter Gene Expression during Human and Murine Erythroid Differentiation. J Biol Chem. 2011 Sep 2; 286(35):30492-503.
Christopher E. Dandoy, MD, MSc 513-636-8424 firstname.lastname@example.org
Instructor, UC Department of Pediatrics
Quality improvement and patient safety; pulmonary hypertension after bone marrow transplantation; cardiopulmonary complications after bone marrow transplantation
Dr. Dandoy is an instructor in clinical pediatrics in the Division of Bone Marrow Transplantation and Immune Deficiency. His aim is to improve the short and long term outcomes of children undergoing bone marrow transplantation through research in early recognition of cardiopulmonary complications from transplant, and the design of reliable healthcare systems at providing safe and effective care.
Dr. Dandoy’s research training includes a master's degree in clinical and translational research from the University of Cincinnati, in addition to advanced training in quality improvement methodology through the Quality Scholars in Healthcare Transformation program at Cincinnati Children’s Hospital Medical Center.
BS: Weber State University, Ogden, UT, 2003.
MD: University of Utah, 2007.
MSc: University of Cincinnati, Cincinnati, OH, 2014.
Residency: Miami Children’s Hospital, Miami, FL, 2010.
Chief Residency: Miami Children’s Hospital, Miami, FL, 2011.
Fellowship: Cincinnati Children's Hospital, Cincinnati Ohio, 2014; Quality Scholar in Healthcare Transformation, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital, Cincinnati, Ohio, 2014.
Certification: Pediatrics, 2010.
Ballen KK, Joffe S, Brazauskas R, Wang Z, Aljurf MD, Akpek G, Dandoy C,
Frangoul HA, Freytes CO, Khera N, Lazarus HM, LeMaistre CF, Mehta P,
Parsons SK, Szwajcer D, Ustun C, Wood WA, Majhail NS. Hospital Length
of Stay in the First 100 Days after Allogeneic Hematopoietic Cell
Transplantation for Acute Leukemia in Remission: Comparison among
Alternative Graft Sources. Biol Blood Marrow Transplant. 2014 Nov;20(11):1819-27.
Kukreja KU, Lungren MP, Patel MN, Racadio JM, Johnson ND, Dandoy C, Tarango C. Enodvascular Venous Thrombolysis in Children Younger Than 24 Months. J Vasc Interv Radiol. 2014 Aug;25(8):1158-64.
Jodele S, Davies SM, Lane A, Khoury J, Dandoy C, Goebel J, Myers K,
Grimley M, Bleesing J, El-Bietar J, Wallace G, Chima RS, Paff Z, Laskin
BL. Diagnostic and risk criteria for HSCT-associated thrombotic microangiopathy: a study in children and young adults. Blood. 2014 Jul 24;124(4):645-53.
Lerner D, Dandoy C, Hirsch R, Laskin B, Davies SM, Jodele S. Pericardial Effusion in Pediatric SCT Recipients with Thrombotic Microangiopathy. Bone Marrow Transplant. 2014 Jun;49(6):862-3.
Dandoy C, Grimley M. Secondary Hemophagocytic Lymphohistiocytosis (HLH) from a Presumed Brown Recluse Spider Bite. J Clin Immunol. 2014;34(5):544-7.
Dandoy C, Gereige RS. Performance-enhancing drugs. Pediatr Rev. 2012 June;33(6):265-71.
Dandoy CE, Hirsch R, Chima R, Davies SM, Jodele S. Pulmonary hypertension after hematopoietic stem cell transplantation. Biol Blood Marrow Transplant. 2013 Nov;19(11):1546-56.
Pauline A. Daniels, DO Staff Physician, Bone Marrow Transplantation and Immune Deficiency 513-636-7287 email@example.com
DO: Lake Erie College of Osteopathic Medicine, Bradenton, FL.
Residency: Pediatrics, University at Buffalo, Buffalo, NY.
Fellowship: Pediatric Hematology/Oncology, University at Buffalo, Buffalo, NY.
Stella M. Davies, MBBS, PhD, MRCP Director, Bone Marrow Transplantation and Immune Deficiency 513-636-1371 firstname.lastname@example.org
Director, Bone Marrow Transplantation and Immune Deficiency
Jacob G. Schmidlapp Endowed Chair
MBBS: University of Newcastle-Upon-Tyne, England, 1981.
Clinical and Fellowship Training: The Royal Victoria Infirmary, Newcastle General Hospital and Great Ormond St. Hospital, 1981 to 1985.
PhD: University of Newcastle-Upon-Tyne, England, 1989.
Pediatric Fellowship: University of Minnesota, Minneapolis, MN, 1989 to 1993.
Mehta PA, Harris RE, Davies SM, Kim MO, Mueller R, Lampkin B, Mo J, Myers K, Smolarek TA. Numerical chromosomal changes and risk of development of myelodysplastic syndrome -- acute myeloid leukemia in patients with Fanconi anemia. Cancer Genet Cytogenet. 2010 Dec;203(2):180-6.
Jodele S, Bleesing JJ, Mehta PA, Filipovich AH, Laskin BL, Goebel J, Pinkard SL, Davies SM. Successful early intervention for hyperacute transplant-associated thrombotic microangiopathy following pediatric hematopoietic stem cell transplantation. Pediatr Transplant. 2010 Nov 5.
Marsh RA, Vaughn G, Kim MO, Li D, Jodele S, Joshi S, Mehta PA, Davies SM, Jordan MB, Bleesing JJ, Filipovich AH. Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation. Blood. 2010 Dec 23;116(26):5824-31.Laskin BL, Goebel J, Davies SM, Khoury JC, Bleesing JJ, Mehta PA, Filipovich AH, Paff ZN, Lawrence JM, Yin HJ, Pinkard SL, Jodele S. Early clinical indicators of transplant-associated thrombotic microangiopathy in pediatric neuroblastoma patients undergoing auto-SCT. Bone Marrow Transplant. 2010 Aug 9.Phillips CL, Gerbing R, Alonzo T, Perentesis JP, Harley IT, Meshinchi S, Bhatla D, Radloff G, Davies SM. MDM2 polymorphism increases susceptibility to childhood acute myeloid leukemia: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 Aug;55(2):248-53.
Mehta PA, Vinks AA, Filipovich A, Bleesing J, Jodele S, Jordan MB, Marsh R, Tarin R, Edwards S, Fearing D, Lawrence J, Davies SM. Alternate-day micafungin antifungal prophylaxis in pediatric patients undergoing hematopoietic stem cell transplantation: a pharmacokinetic study. Biol Blood Marrow Transplant. 2010 Oct;16(10):1458-62.
Sakagami T, Beck D, Uchida K, Suzuki T, Carey BC, Nakata K, Keller G, Wood RE, Wert SE, Ikegami M, Whitsett JA, Luisetti M, Davies S, Krischer JP, Brody A, Ryckman F, Trapnell BC. Patient-derived granulocyte / macrophage colony-stimulating factor autoantibodies reproduce pulmonary alveolar proteinosis in nonhuman primates. Am J Respir Crit Care Med. 2010 Jul 1;182(1):49-61.
Wang D, Zhang W, Kalfa TA, Grabowski G, Davies S, Malik P, Pan D. Reprogramming erythroid cells for lysosomal enzyme production leads to visceral and CNS cross-correction in mice with Hurler syndrome. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19958-63.
Davies SM, Wang D, Wang T, Arora M, Ringden O, Anasetti C, Pavletic S, Casper J, Macmillan ML, Sanders J, Wall D, Kernan NA. Recent decrease in acute graft-versus-host disease in children with leukemia receiving unrelated donor bone marrow transplants. Biol Blood Marrow Transplant. 2009 Mar;15(3):360-6.
Myers KC, Davies SM. Hematopoietic stem cell transplantation for bone marrow failure syndromes in children. Biol Blood Marrow Transplant. 2009 Mar;15(3):279-92. Review.
Laura Diggs, APRN, CFNP Nurse Practitioner, Bone Marrow Transplantation and Immune Deficiency 513-636-6698 email@example.com
Nurse Practitioner, Bone Marrow Transplantation and Immune Deficiency
Javier El-Bietar, MD 513-803-2105 firstname.lastname@example.org
Pediatric bone marrow transplantation
Javier El-Bietar, MD, received his medical degree from St. George's University School of Medicine, Grenada, West Indies. He then pursued residency training in general pediatrics at SUNY Downstate in Brooklyn New York where he received an Excellence in Research Award. He continued training in pediatric hematology/oncology at Baylor College of Medicine, Texas Children's Hospital, Houston, TX, where he conducted research exploring the in vitro enhancement of antigen specific cytotoxic T cells used in adoptive immunotherapy. He spent an additional clinical training year with Texas Children's Hospital and the Center for Cell and Gene Therapy following the bone marrow transplant fellowship curriculum. After completion, he joined the faculty at Cincinnati Children’s in the Division of Bone Marrow Transplantation and Immune Deficiency in 2013. His clinical and research interests include exploring new treatment strategies for post-hematopoietic stem cell transplant-associated co-morbidities.
MD: St. George's University School of Medicine, Grenada, West Indies, 2006.
Residency: Pediatrics, State University of New York, Downstate, Brooklyn, New York, NY.
Fellowship: Pediatric Hematology/Oncology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
Board Certification: Pediatrics, 2009; Pediatric Hematology/Oncology, 2013.
El-Bietar JA, Bollard CM. T cell therapies for Epstein-Barr virus-associated lymphomas. Pediatric Hematology and Oncology. 2011 Nov; 28(8):627-39.
Dvorak CC, Bollard CM, El-Bietar J, Filipovich A. Complications of Transplant for Nonmalignant Disorders: Autoimmune Cytopenias, Opportunistic Infections, and PTLD. Educational series. American Society of Bone Marrow Transplant Annual Meeting 2012. Biology and Bone Marrow Transplant. 2012 Jan; 18(1 Suppl):S101-10.
Fallon SC, Redell MS, El-Bietar J, Lopez ME, Vasudevan SA, Brandt ML. Intestinal perforation after treatment of Burkitt’s lymphoma: Case report and review of the literature. Journal of Pediatric Surgery. 2013 Feb; 48(2):436-40.
Alexandra (Lisa) H. Filipovich, MD Ralph J. Stolle Chair, Clinical Immunology 513-803-3218 email@example.com
Ralph J. Stolle Chair, Clinical Immunology
Director, Immune Deficiency and Histiocytosis Program
Medical Director, Diagnostic Immunology Laboratory