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The Cancer and Blood Diseases Institute is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.
Our divisions are led by the following:
Oncology: John Perentesis, DirectorHematology: Russell Ware, DirectorExperimental Hematology and Cancer Biology: Yi Zheng, DirectorBone Marrow Transplantation / Immune Deficiency: Stella Davies, Director
Stefanie W. Benoit, MD, MPH Staff Physician, Cancer and Blood Diseases Institute
Staff Physician, Cancer and Blood Diseases Institute
MD: Case Western Reserve University, Cleveland, OH, 2010.
Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.
Jacob [Jack] J.H. Bleesing, MD, PhD
Associate Professor, UC Department of Pediatrics
Immunobiology; translational research; immunologic methods development
Clinical investigation of primary immunodeficiency disorders (with emphasis on disorders of immuno dysregulation and B-cell disorders); immuno-reconstitution following blood and marrow transplantation; diagnostic immunology (with emphasis on flow cytometry)
Jodele S, Bleesing JJ, Mehta PA, Filipovich AH, Laskin BL, Goebel J, Pinkard SL, Davies SM. Successful early intervention for hyperacute transplant-associated thrombotic microangiopathy following pediatric hematopoietic stem cell transplantation. Pediatr Transplant. 2010 Nov 5. Eckrich MJ, Yang E, Domm J, Ho R, Calder C, Manes B, Bleesing J, Frangoul H. A Unique Clinical Presentation of X-Linked Lymphoproliferative Syndrome With a Novel Mutation in SH2D1A and Review of the Literature. J Pediatr Hematol Oncol. 2010 Oct 21. Marsh RA, Bleesing JJ, Filipovich AH. Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiency. J Immunol Methods. 2010 Oct 31;362(1-2):1-9. Marsh RA, Villanueva J, Kim MO, Zhang K, Marmer D, Risma KA, Jordan MB, Bleesing JJ, Filipovich AH. Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations. Clin Immunol. 2009 Jul;132(1):116-23.
Marsh RA, Villanueva J, Zhang K, Snow AL, Su HC, Madden L, Mody R, Kitchen B, Marmer D, Jordan MB, Risma KA, Filipovich AH, Bleesing JJ. A rapid flow cytometric screening test for X-linked lymphoproliferative disease due to XIAP deficiency. Cytometry B Clin Cytom. 2009 Sep;76(5):334-44. Hansen MD, Filipovich AH, Davies SM, Mehta P, Bleesing J, Jodele S, Hayashi R, Barnes Y, Shenoy S. Allogeneic hematopoietic cell transplantation (HCT) in Hurler's syndrome using a reduced intensity preparative regimen. Bone Marrow Transplant. 2008 Feb;41(4):349-53. Bhatla D, Davies SM, Shenoy S, Harris RE, Crockett M, Shoultz L, Smolarek T, Bleesing J, Hansen M, Jodele S, Jordan M, Filipovich AH, Mehta PA. Reduced-intensity conditioning is effective and safe for transplantation of patients with Shwachman-Diamond syndrome. Bone Marrow Transplant. 2008 Aug;42(3):159-65.
Zhang K, Johnson JA, Biroschak J, Villanueva J, Lee SM, Bleesing JJ, Risma KA, Wenstrup RJ, Filipovich AH. Familial haemophagocytic lymphohistiocytosis in patients who are heterozygous for the A91V perforin variation is often associated with other genetic defects. Int J Immunogenet. 2007 Aug;34(4):231-3.
JJH Bleesing. Assays for B Cell and Germinal Center Development (unit 7.34). In Current Protocols in Immunology. JE Coligan, BE Bierer, DH Margulies, EM Shevach, W Strober (eds.). Hoboken: John Wiley & Sons, 2004. JJH Bleesing, TA Fleisher, JM Puck. Autoimmune lymphoproliferative syndrome (ALPS). In Immunologic Disorders in Infants and Children. 5th ed. ER Stiehm, HD Ochs, JA Winkelstein (eds). Philadelphia, PA: WB Saunders, 2004.
Sharat Chandra, MBBS, MD, MRCPCH
Instructor, UC Department of Pediatrics
MBBS: Andhra Medical College, University of Health Sciences, Visakhapatnam, India.
Residency: Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India, 1998-2001; University Hospitals of Leicester, South Warwickshire Hospitals NHS, United Kingdom, 2003-2006; University of South Alabama, 2006-2009.
Fellowship: Pediatric Hematology-Oncology, Cincinnati Children’s Hospital Medical Center, 2009-2012.
Certification: MD (Pediatrics), 2001; Royal College of Pediatrics and Child Health (MRCPCH), 2006; Board Certified in General Pediatrics by the American Board of Pediatrics, 2009; Board Certified in Pediatric Hematology-Oncology by the American Board of Pediatrics, 2013.
Singh M, Mathew JL, Chandra S, Katariya S, Kumar L. Randomized controlled trial of intrapleural streptokinase in empyema thoracis in children. Acta Paediatrica. 2004 Nov; 93(11):1443-5.
Chandra S, Haines H, Michie C, Maheshwari A. Developmental Defec