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Cardiology

 

  • Meet the Team

    Meet the team members of the Heart Institute's Cardiology Clinic at Cincinnati Children's Hospital Medical Center.

  • Show All

    Medical Director

    A photo of Thomas Kimball.

    Thomas R. Kimball, MD
    Medical Director, Heart Institute

    513-636-8270

    tom.kimball@cchmc.org

    A photo of Thomas Kimball.
    High Res

    Thomas R. Kimball, MD

    Medical Director, Heart Institute

    Professor, UC Department of Pediatrics

    Phone: 513-636-8270

    Fax: 513-636-3952

    Email: tom.kimball@cchmc.org

    Show All

    Specialties

    Clinical Interest

    Congential heart disease; echocardiography; cardiac imaging

    Research Interests

    Ventricular function; transgenic mice phenotyping; cardiovascular changes with obstructive sleep apnea; cardiovascular changes with renal disease; pediatric obesity; cardiovascular changes in fit and unfit children; echocardiography quality assurance

    Biography

    Thomas R. Kimball, MD, is a professor of pediatrics with the University of Cincinnati College of Medicine and is currently the medical director of the Heart Institute at Cincinnati Children's Hospital Medical Center.

    A native of California, Dr. Kimball graduated with Distinction and Honors from Stanford University. He earned his medical degree from New York University, New York, NY.  He completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center. 

    Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988.

    Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.

    He has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.

    Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network. 

    He was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.

    In 2010, he was made the Medical Director of the Heart Institute at Cincinnati Children's Hospital. 

    Education and Training

    BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.

    MD: New York University School of Medicine, New York City, NY, 1982. 

    Residency: Children's Hospital of Los Angeles, Los Angeles, CA, 1985. 

    Fellowship: Children's Hospital Medical Center, Cincinnati, OH, 1988. 

    Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).

    Publications

    View PubMed Publications

    Cardiologists

    A photo of Robert Beekman.
    High Res

    Robert H. Beekman III, MD

    Professor, UC Department of Pediatrics

    Phone: 513-636-7072

    Fax: 513-636-2410

    Email: rbeekman@cchmc.org

    Show All

    Specialties

    Cardiac catheterization; intervention for congenital heart disease; quality improvement

    Biography

    Robert H. Beekman, III, MD, is currently a professor of Pediatric Cardiology at Children's Hospital Medical Center of Cincinnati, Ohio. Dr. Beekman's subspecialty interests involve cardiac catheterization and interventional cardiology, and clinical quality improvement.

    A native of California, Dr. Beekman graduated from Occidental College in Los Angeles, and earned his MD from Duke University in Durham, NC. Dr. Beekman completed his pediatric internship and residency at UCLA Medical Center, and his pediatric cardiology fellowship at the University of Michigan Medical Center, Ann Arbor, MI. Dr. Beekman also obtained a Master's Degree in Statistical Analysis and Research Design from the University of Michigan. From 1985 to 1996, Dr. Beekman was a member of the Division of Pediatric Cardiology at the University of Michigan School of Medicine. From 1996-2006 he was Director of Cardiology at Children's Hospital Medical Center of Cincinnati, and professor of Pediatrics at the University of Cincinnati School of Medicine.

    Dr. Beekman's academic interests relate to cardiac catheterization, and he has made numerous scholarly contributions in the field of hemodynamic assessment and transcatheter intervention for congenital heart disease.  He has published more than 170 manuscripts in cardiology journals.

    Dr. Beekman has been active in the cardiology community, locally and nationally. He is Chair of the Section on Cardiology and Cardiac Surgery of the American Academy of Pediatrics. Beekman also is the Chair of the JCCHD National Quality Improvement Collaborative for pediatric cardiology. Dr. Beekman has been a member of the Executive Committee and the Training Committee of the AHA Council on Cardiovascular Disease in the Young, and of the Congenital Heart Committee of the ACC. He is currently on the editorial board of the Journal of Interventional Cardiology, a contributing editor of theHeart.org, an Internet cardiology journal, and an associate editor of Congenital Heart Disease.

    Education and Training

    MD: Duke University School of Medicine, Durham, NC, 1976.

    MS: Clinical Research Design and Statistics, University of Michigan, Ann Arbor, MI, 1986.

    Residency: Pediatrics, UCLA Medical Center, Los Angeles, CA, 1976 to 1979.

    Fellowship: Pediatric Cardiology, CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 1979 to 1982.

    Certification: Pediatrics, 1981; Pediatric Cardiology, 1983.

    Publications

    View PubMed Publications
    Doctor Cnota is an Associate Professor of Cardiology.
    High Res

    James F. Cnota, MD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-0426

    Email: james.cnota@cchmc.org

    Show All

    Specialties

    Clinical Interests

    Fetal cardiology including fetal echocardiography

    Research Interests

    Impact of insulin sensitivity on left ventricular mass in healthy teens; blood pressure in offspring of preeclamptic mothers; fetal programming of cardiovascular outcomes; multicenter trials in pediatric heart disease

    Education and Training

    BS: Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, 1991

    MD: Tulane University School of Medicine, New Orleans, Louisiana, 1995

    Residency: University of Arizona Health Sciences Center, Tucson, Arizona, 1998

    Fellowship: Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2001

    MS: Clinical Epidemiology and Health Services Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, 2005

    Publications

    View PubMed Publications

    A photo of Allison A. Divanovic.
    High Res

    Allison A. Divanovic, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-3867

    Fax: 513-636-3952

    Email: allison.divanovic@cchmc.org

    Show All

    Education and Training

    MD: Univeristy of Cincinnati, Cincinnati, OH

    Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Publications

    View PubMed Publications
    A photo of Bryan Goldstein.
    High Res

    Bryan H. Goldstein, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-7072

    Fax: 513-636-2410

    Email: bryan.goldstein@cchmc.org

    Show All

    Specialties

    Cardiac catheterization; intervention for congenital heart disease; transcatheter valve implantation; single ventricle physiology

    Biography

    Bryan H. Goldstein, MD joined the Heart Institute in August 2011 in the section of cardiac catheterization and intervention. He was previously a clinical lecturer at the University of Michigan where he completed fellowship training. 

    A native of Boston, MA, Dr. Goldstein graduated with Distinction and Honors from Amherst College, where he was a goalie on the men's lacrosse team.  He earned his medical degree with Honors from Boston University School of Medicine.  He completed his pediatric internship and residency in the Boston Combined Residency in Pediatrics (Children's Hospital Boston) and his pediatric cardiology and interventional cardiology fellowships at the University of Michigan (C.S. Mott Children's Hospital) in Ann Arbor, MI.

    Dr. Goldstein’s clinical expertise is in congenital cardiac catheterization. He is interested in invasive physiologic assessment of complex congenital heart disease, including single ventricle physiology, as well as minimally invasive transcatheter therapies.  Dr. Goldstein is also interested in furthering hybrid therapies offered for congenital heart disease in patients both young and old.

    Dr. Goldstein’s research interests include novel transcatheter interventions (including fetal therapy) and long-term outcomes following interventions for congenital heart disease. An additional research focus includes long-term functional outcomes following Fontan palliation for single ventricle physiology. Dr. Goldstein previously served as a co-investigator for the Melody™ Transcatheter Pulmonary Valve Post-Approval Study.

    Dr. Goldstein is an active member of the American Heart Association, American College of Cardiology, Society of Cardiovascular Angiography and Interventions, and American Academy of Pediatrics.


    Education and Training

    MD: Boston University School of Medicine, Boston, MA, 2004.

    Residency: Pediatrics, Children’s Hospital Boston, Boston, MA, 2007. 

    Fellowship: Pediatric Cardiology, C.S. Mott Children’s Hospital, Ann Arbor, MI, 2010.

    Advanced Fellowship: Interventional Cardiology, C.S. Mott Children’s Hospital, Ann Arbor, MI, 2011.

    Certifications: Pediatrics, 2007; Pediatric Cardiology, 2010. 

    Publications

    View PubMed Publications

    A photo of Haleh C. Heydarian, MD.

    Haleh C. Heydarian, MD

    513-636-6646

    A photo of Haleh C. Heydarian, MD.
    High Res

    Haleh C. Heydarian, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-6646

    Fax: 513-636-3982

    Show All

    Specialties

    Clinical Interests

    Echocardiography

    Research Interests

    Dyssynchrony; quality improvement

    Education and Training

    MD: Marshall University, Huntington, West Virginia.

    Residency: Pediatrics, Nationwide Children’s Hospital, Columbus, Ohio.

    Fellowship: Cincinnati Children’s Hospital, Cincinnati, Ohio.
    A photo of Thomas Kimball.

    Thomas R. Kimball, MD
    Medical Director, Heart Institute

    513-636-8270

    tom.kimball@cchmc.org

    A photo of Thomas Kimball.
    High Res

    Thomas R. Kimball, MD

    Medical Director, Heart Institute

    Professor, UC Department of Pediatrics

    Phone: 513-636-8270

    Fax: 513-636-3952

    Email: tom.kimball@cchmc.org

    Show All

    Specialties

    Clinical Interest

    Congential heart disease; echocardiography; cardiac imaging

    Research Interests

    Ventricular function; transgenic mice phenotyping; cardiovascular changes with obstructive sleep apnea; cardiovascular changes with renal disease; pediatric obesity; cardiovascular changes in fit and unfit children; echocardiography quality assurance

    Biography

    Thomas R. Kimball, MD, is a professor of pediatrics with the University of Cincinnati College of Medicine and is currently the medical director of the Heart Institute at Cincinnati Children's Hospital Medical Center.

    A native of California, Dr. Kimball graduated with Distinction and Honors from Stanford University. He earned his medical degree from New York University, New York, NY.  He completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center. 

    Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988.

    Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.

    He has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.

    Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network. 

    He was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.

    In 2010, he was made the Medical Director of the Heart Institute at Cincinnati Children's Hospital. 

    Education and Training

    BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.

    MD: New York University School of Medicine, New York City, NY, 1982. 

    Residency: Children's Hospital of Los Angeles, Los Angeles, CA, 1985. 

    Fellowship: Children's Hospital Medical Center, Cincinnati, OH, 1988. 

    Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).

    Publications

    View PubMed Publications

    A photo of Christopher Learn.
    High Res

    Christopher P. Learn, MD

    Assistant Professor, UC Department of Pediatrics

    Assistant Professor, UC Department of Internal Medicine

    Phone: 513-803-2243

    Email: christopher.learn@cchmc.org

    Show All

    Specialties

    Adolescent and adult congenital heart disease; non-invasive cardiovascular imaging

    Education and Training

    MD: Boston University, Boston, MA, 2003.

    Residency: Internal Medicine-Pediatrics, Indiana University Hospital, Indianapolis, IN, 2007.

    Fellowship: Cardiovascular Medicine, The Ohio State University Medical Center, Columbus, OH, 2012. Pediatric Cardiology, Nationwide Children’s Hospital, Columbus, OH, 2012.

    Certification: Internal Medicine, 2008, General Pediatrics, 2008; board eligible Pediatric Cardiology and (Adult) Cardiovascular Medicine.

    Publications

    View PubMed Publications
    A photo of Lisa Lee.

    Lisa A. Lee, MD
    Pediatric Cardiologist, Heart Institute / Cardiology Clinic

    859-344-4732

    lisa.lee@cchmc.org

    A photo of Lisa Lee.
    High Res

    Lisa A. Lee, MD

    Pediatric Cardiologist, Heart Institute / Cardiology Clinic

    University of Cincinnati College of Medicine

    Phone: 859-344-4732

    Fax: 859-344-4752

    Email: lisa.lee@cchmc.org

    Show All

    Specialties

    Outpatient clinical management of cardiac disease; echocardiography

    Biography

    Lisa A. Lee, MD, is committed to expanding the cardiology outpatient services in Northern Kentucky. She staffs the satellite clinic at Outpatient Kentucky three days per week and offers all non-invasive cardiac services including echocardiograms, electrocardiograms (ECG), holter monitors and event monitors. She can be reached at 859-344-4732. Appointments can be scheduled by calling 513-636-9477.

    Education and Training

    BA: Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 1989.

    MD: University of Cincinnati College of Medicine, Cincinnati, Ohio, 1993.

    Residency: Cincinnati Children's Hospital, Cincinnati, Ohio, 1993-1996.

    Fellowships: Pediatric Resident, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1994-1996. Pediatric Cardiology, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan 1997-2000; Pediatric Echocardiography, Cincinnati Children's Hospital, Cincinnati, Ohio, 2000-2001.

    Certification: Pediatrics, 1996; Pediatric Cardiology, 2000.

    Publications

    View PubMed Publications

    A photo of Nicolas Madsen.
    High Res

    Nicolas L. Madsen, MD, MPH

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-5476

    Email: nicolas.madsen@cchmc.org

    Show All

    Specialties

    Inpatient and preventative cardiology

    Biography

    Nicolas L. Madsen, MD, MPH joined the Heart Institute in July 2012. He attended the University of California at Davis, where he graduated with honors. He earned his medical degree with honors at the University of Washington in 2005. Dr. Madsen completed his residency in General Pediatrics and his fellowship in Pediatric Cardiology at Seattle Children’s Hospital in Seattle, Washington. In addition, Dr. Madsen earned a Master’s in Public Health from the University of Washington in 2011.

    Dr. Madsen’s clinical focus is in general and preventative cardiology. His research interests also focus on the prevention of cardiac disease processes. Specifically, Dr. Madsen aims to understand the implications of traditional cardiovascular risk factors such as obesity, hypertension and sedentary lifestyle on persons with congenital heart disease. Additionally, he is focused on the prevention of sudden cardiac death in adolescent athletes by way of optimizing preparticipation sports screening. Dr. Madsen has received several national awards for his research and is an active member of the American Heart Association and American Academy of Pediatrics.

    Education and Training

    MD: University of Washington School of Medicine, Seattle, WA, 2005.

    MPH: University of Washington School of Public Health, Seattle, WA, 2011.

    Residency: Pediatrics, Seattle Children’s Hospital, Seattle, WA.

    Fellowship: Cardiology, Seattle Children’s Hospital, Seattle, WA.

    Publications

    A photo of Peace Madueme.
    High Res

    Peace C. Madueme, MD

    Instructor, UC Department of Pediatrics

    Phone: 513-636-3866

    Fax: 513-363-3952

    Email: peace.madueme@cchmc.org

    Show All

    Specialties

    Pediatric cardiology; exercise; echocardiography
     

    Education and Training

    MD: Eastern Virginia Medical School, Norfolk, VA.

    Residency: Cincinnati Children's Hospital Medical Center.

    A photo of Erik Michelfelder.

    Erik C. Michelfelder, MD
    Director of the Fetal Cardiac Program

    513-636-1199

    erik.michelfelder@cchmc.org

    A photo of Erik Michelfelder.
    High Res

    Erik C. Michelfelder, MD

    Director of the Fetal Cardiac Program

    Co-Director of Cardiac Imaging

    Professor, UC Department of Pediatrics

    Phone: 513-636-1199

    Fax: 513-636-7468

    Email: erik.michelfelder@cchmc.org

    Show All

    Specialties

    Echocardiography; fetal cardiology; pediatric cardiology

    Biography

    Erik C. Michelfelder Sr., MD is an Associate Professor of Pediatrics with the University of Cincinnati College of Medicine.  He is currently Director of the Fetal Heart Program, and Co-Director of Cardiac Imaging Services for the Heart Institute at Cincinnati Children’s Hospital Medical Center.

    Dr. Michelfelder graduated with a degree in Biology from Bucknell University and earned his M.D. from the Penn State University College of Medicine.  He completed his residency in pediatrics at St. Christopher’s Hospital for Children in Philadelphia, and his cardiology fellowship at C.S. Mott Children’s Hospital at the University of Michigan in Ann Arbor.

    Dr. Michelfelder has been a member of the Division of Cardiology at Cincinnati Children’s Hospital Medical Center since 1998.  His clinical and academic focus relate to fetal cardiology and echocardiography.

    He is a member of the American Society of Echocardiography, The American Heart Association, The American College of Cardiology, The American Academy of Pediatrics, and the Society for Pediatric Research.

     

    Education and Training

    BS: Bucknell University, Lewisburg, PA, 1986.

    MD: Penn State University College of Medicine, Hershey, Pennsylvania, 1990.

    Residency: St. Christopher's Hospital for Children, Temple University School of Medicine, Philadelphia, Pennsylvania, 1990-1993.

    Fellowship: C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, 1993-1996.

    Certification: Pediatrics 1991, Pediatric Cardiology 1998.

    Publications

    View PubMed Publications
    A photo of Joshua Sticka.

    Joshua J. Sticka, MD
    Cardiologist, Heart Institute

    513-636-9806

    joshua.sticka@cchmc.org

    A photo of Joshua Sticka.
    High Res

    Joshua J. Sticka, MD

    Cardiologist, Heart Institute

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-9806

    Email: joshua.sticka@cchmc.org

    Show All

    Specialties

    Cardiac MRI; transthoracic and transesophageal echocardiography; myocardial mechanics

    Biography

    Joshua Sticka, MD, is an assistant professor of pediatrics at University of Cincinnati and a clinical cardiologist within the Heart Institute at Cincinnati Children’s Hospital Medical Center.

    Dr. Sticka is a native of Montana and completed his undergraduate degree with honors in astrophysics at the University of Montana. While in medical school at the University of Washington School of Medicine he was selected to participate in the highly competitive WRITE program and studied rural medicine in northern Idaho. During his pediatric training at the University of California San Diego he won several awards and was asked to stay on to work as an attending physician at Rady Children’s Hospital in the department of Emergency Medicine. He subsequently moved to Denver, CO to obtain his pediatric cardiology training from the University of Colorado and completed an additional year of advanced fellowship training in non-invasive cardiac imaging there as well.

    Dr. Sticka joined the imaging section of the Heart Institute in August 2011 as a clinical cardiologist with specialization in cardiac MRI and echocardiography.

    Education and Training

    MD:  University of Washington School of Medicine, Seattle, WA,  2003.

    Residency:  Pediatrics, University of California San Diego, San Diego, CA,  2006.

    Fellowship:  Pediatric Cardiology, University of Colorado, Denver, CO,  2010.

    Advanced Fellowship:  Non-invasive Cardiac Imaging, University of Colorado, Denver, CO,  2011.

    Certification:  Pediatrics, 2007.

    Publications


    A photo of Dr. Arnold Strauss.

    Arnold W. Strauss, MD
    BK Rachford Professor and Chair, Department of Pediatrics, University of Cincinnati College of Medicine

    513-636-2942

    arnold.strauss@cchmc.org

    A photo of Dr. Arnold Strauss.
    High Res

    Arnold W. Strauss, MD

    BK Rachford Professor and Chair, Department of Pediatrics, University of Cincinnati College of Medicine

    Director, Cincinnati Children's Research Foundation

    Chief Medical Officer, Cincinnati Children's Hospital Medical Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-2942

    Email: arnold.strauss@cchmc.org

    Show All

    Specialties

     Pediatric cardiology; genetic basis of pediatric heart disease

    Biography

    Arnold Strauss, MD, joined Cincinnati Children's in April, 2007, as chairman of the Department of Pediatrics at the UC College of Medicine, chief medical officer of Cincinnati Children's and director of the Cincinnati Children's Research Foundation. He is the seventh B.K. Rachford Memorial Chair in Pediatrics.

    Dr. Strauss is a distinguished pediatric cardiologist, scientist, educator and leader. Prior to his arrival at Cincinnati Children's, he was the chairman of the Department of Pediatrics at the Vanderbilt University School of Medicine and medical director of the Monroe Carell Jr. Children's Hospital at Vanderbilt, a position he held from 2000 to 2007. Under his leadership, the university built and opened a new hospital for children, expanded its pediatric faculty and increased grant funding for pediatric research. From 1981 to 2000, Strauss was director of the Division of Pediatric Cardiology at Washington University/St. Louis Children's Hospital.

    A respected scientist, Dr. Strauss' research focuses on understanding the molecular basis of disorders of mitochondrial fatty acid oxidation and the genetic causes of congenital heart disease and cardiomyopathies. He is the recipient of two of the most prestigious awards in research. In November 2006 he was awarded the American Heart Association's Basic Science Research Award for groundbreaking work that led to finding genetic defects that can cause heart failure and sudden death in infants and children. In 1991 he received the E. Mead Johnson Award for Excellence in Pediatric Research.

    Education and Training

    MD Washington University, St. Louis, Missouri, 1970.

    Residency Pediatrics, Children's Hospital, St. Louis, Missouri, 1970-72.

    Fellowship Cardiology, Children's Hospital and Washington University, St. Louis, Missouri, 1972-75.

    Postdoctoral Fellowship Merck, Sharp and Dohme Research Laboratories, Rahway, New Jersey, 1975-77.

    Publications

    Liebig M, Schymik I, Mueller M, Wendel U, Mayatepek E, Ruiter J, Strauss AW, Wanders RJ, Spiekerkoetter U. (2006) Neonatal screening for very long-chain acyl-coA dehydrogenase deficiency: enzymatic and molecular evaluation of neonates with elevated C14:1-carnitine levels. Pediatrics 118:1065-9.

    Khuchua Z, Yue Z, Batts L, Strauss AW. (2006) A zebrafish model of human Barth syndrome reveals the essential role of tafazzin in cardiac development and function. Circ Res 99:201-8.

    Exil VJ, Gardner CD, Rottman JN, Sims H, Bartelds B, Khuchua Z, Sindhal R, Ni G, Strauss AW. (2006) Abnormal mitochondrial bioenergetics and heart rate dysfunction in mice lacking very-long-chain acyl-CoA dehydrogenase. Am J Physiol Heart Circ Physiol 290:H1289-97.

    Bennett MJ, Russell LK, Tokunaga C, Narayan SB, Tan L, Seegmiller A, Boriack RL, Strauss AW. (2006) Reye-like syndrome resulting from novel missense mutations in mitochondrial medium- and short-chain l-3-hydroxy-acyl-CoA dehydrogenase. Mol Genet Metab 89:74-9.

    Strauss AW. (2005) Surprising? Perhaps not. Long-chain fatty acid oxidation during human fetal development. Pediatr Res 57:753-4.

    Spiekerkoetter U, Tokunaga C, Wendel U, Mayatepek E, Ijlst L, Vaz FM, van Vlies N, Overmars H, Duran M, Wijburg FA, Wanders RJ, Strauss AW. (2005) Tissue carnitine homeostasis in very-long-chain acyl-CoA dehydrogenase-deficient mice. Pediatr Res 57:760-4.

    Shekhawat PS, Matern D, Strauss AW. (2005) Fetal fatty acid oxidation disorders, their effect on maternal health and neonatal outcome: impact of expanded newborn screening on their diagnosis and management. Pediatr Res 57:78R-86R.

    Djouadi F, Aubey F, Schlemmer D, Ruiter JP, Wanders RJ, Strauss AW, Bastin J. (2005) Bezafibrate increases very-long-chain acyl-CoA dehydrogenase protein and mRNA expression in deficient fibroblasts and is a potential therapy for fatty acid oxidation disorders. Hum Mol Genet 14:2695-703.

    Browning MF, Larson C, Strauss A, Marsden DL. (2005) Normal acylcarnitine levels during confirmation of abnormal newborn screening in long-chain fatty acid oxidation defects. J Inherit Metab Dis 28:545-50.

    Strauss AW. (2004) Tandem mass spectrometry in discovery of disorders of the metabolome. J Clin Invest 113:354-6.

    Spierkerkoetter U, Khuchua Z, Yue Z, Strauss AW. (2004) The early-onset phenotype of mitochondrial trifunctional protein deficiency: a lethal disorder with multiple tissue involvement. J Inherit Metab Dis 27:294-6.

    Spiekerkoetter U, Tokunaga C, Wendel U, Mayatepek E, Exil V, Duran M, Wijburg FA, Wanders RJ, Strauss AW. (2004) Changes in blood carnitine and acylcarnitine profiles of very long-chain acyl-CoA dehydrogenase-deficient mice subjected to stress. Eur J Clin Invest 34:191-6.

    Spiekerkoetter U, Khuchua Z, Yue Z, Bennett MJ, Strauss AW. (2004) General mitochondrial trifunctional protein (TFP) deficiency as a result of either alpha- or beta-subunit mutations exhibits similar phenotypes because mutations in either subunit alter TFP complex expression and subunit turnover. Pediatr Res 55:190-6.

    Spiekerkoetter U, Bennett MJ, Ben-Zeev B, Strauss AW, Tein I. (2004) Peripheral neuropathy, episodic myoglobinuria, and respiratory failure in deficiency of the mitochondrial trifunctional protein. Muscle Nerve 29:66-72.

    McKinney JT, Longo N, Hahn SH, Matern D, Rinaldo P, Strauss AW, Dobrowolski SF. (2004) Rapid, comprehensive screening of the human medium chain acyl-CoA dehydrogenase gene. Mol Genet Metab 82:112-20.

    Strauss A, Lock JE. (2003) Pediatric cardiomyopathy--a long way to go. N Engl J Med 348:1703-5.

    Spiekerkoetter U, Sun B, Zytkovicz T, Wanders R, Strauss AW, Wendel U. (2003) MS/MS-based newborn and family screening detects asymptomatic patients with very-long-chain acyl-CoA dehydrogenase deficiency. J Pediatr 143:335-42.

    Spiekerkoetter U, Sun B, Khuchua Z, Bennett MJ, Strauss AW. (2003) Molecular and phenotypic heterogeneity in mitochondrial trifunctional protein deficiency due to beta-subunit mutations. Hum Mutat 21:598-607.

    Shekhawat P, Bennett MJ, Sadovsky Y, Nelson DM, Rakheja D, Strauss AW. (2003) Human placenta metabolizes fatty acids: implications for fetal fatty acid oxidation disorders and maternal liver diseases. Am J Physiol Endocrinol Metab 284:E1098-105.

    Khuchua Z, Wozniak DF, Bardgett ME, Yue Z, McDonald M, Boero J, Hartman RE, Sims H, Strauss AW. (2003) Deletion of the N-terminus of murine map2 by gene targeting disrupts hippocampal ca1 neuron architecture and alters contextual memory. Neuroscience 119:101-11.

    Exil VJ, Roberts RL, Sims H, McLaughlin JE, Malkin RA, Gardner CD, Ni G, Rottman JN, Strauss AW. (2003) Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice. Circ Res 93:448-55.

    Zytkovicz TH, Fitzgerald EF, Marsden D, Larson CA, Shih VE, Johnson DM, Strauss AW, Comeau AM, Eaton RB, Grady GF. (2001) Tandem mass spectrometric analysis for amino, organic, and fatty acid disorders in newborn dried blood spots: a two-year summary from the New England Newborn Screening Program. Clin Chem 47:1945-55.

    Ibdah JA, Paul H, Zhao Y, Binford S, Salleng K, Cline M, Matern D, Bennett MJ, Rinaldo P, Strauss AW. (2001) Lack of mitochondrial trifunctional protein in mice causes neonatal hypoglycemia and sudden death. J Clin Invest 107:1403-9.

    Barycki JJ, O'Brien LK, Strauss AW, Banaszak LJ. (2000) Sequestration of the active site by interdomain shifting. Crystallographic and spectroscopic evidence for distinct conformations of L-3-hydroxyacyl-CoA dehydrogenase. J Biol Chem 275:27186-96.

    Ibdah JA, Bennett MJ, Rinaldo P, Zhao Y, Gibson B, Sims HF, Strauss AW. (1999) A fetal fatty-acid oxidation disorder as a cause of liver disease in pregnant women. N Engl J Med 340:1723-31.

    Grants

    Adaptation to Long Chain Fatty Acid Oxidation Deficiency
    1R01HL075421, Active | 04/01/04-03/31/08 | NHLBI | Principal Investigator
    The goals of this project are to examine genotype-phenotype correlations and the pathogenetics of very-long-chain acyl-CoA dehydrogenase deficiency in humans, to characterize a mouse model of VLCAD deficiency, to create and analyze tissue-specific VLCAD knockouts, and to define the role of heart endothelin related substance in adaptation in the VLCAD knockout mouse. These studies utilize many of the techniques of the current application, including proteomics and DNA microarray experiments. Drs. Khuchua and Strauss developed tissue-specific knockout approaches and detailed physiologic studies in HL-75421.
     
    Training Program in Pediatric Cardiopulmonary Research
    5T32 HL007256 | 07/01/77-06/30/07 | NIH/NIHLBI | Principal Investigator
    This institutional training grant is for graduate students and post-doctoral fellows.
     
    NICHD Institutional Training for Pediatricians
    1T32HD044328 | 06/01/03-04/30/08 | NIH/NICHD | Principal Investigator
    This institutional training grant is for physician post-doctoral fellows to develop expertise in patient-based research.

    Stipend and benefit Support is available to qualified candidates through NHLBI Training Grant: T-32 HL07382-30: "Training In Cardiovascular Biology", Dr. Arnold Schwartz, Principal Investigator.
    A photo of Jeffrey Towbin.

    Jeffrey A. Towbin, MD, FAAP, FACC, FAHA
    Executive Co-Director, The Heart Institute; Chief, Pediatric Cardiology

    513-636-3049

    jeffrey.towbin@cchmc.org

    A photo of Jeffrey Towbin.
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    Jeffrey A. Towbin, MD, FAAP, FACC, FAHA

    Executive Co-Director, The Heart Institute; Chief, Pediatric Cardiology

    UC Department of Pediatrics

    Phone: 513-636-3049

    Email: jeffrey.towbin@cchmc.org

    Show All

    Education and Training

    BS: Biology, University of Cincinnati, 1974.

    MS: Cell Biology, University of Cincinnati, 1977.

    MD: University of Cincinnati, 1982.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, 1985.

    Fellowship: Pediatric Cardiology, Baylor College of Medicine, Texas Children's Hospital, 1989.

    Publications

    View PubMed Publications

    Grants

    Pediatric Cardiomyopathy Registry. Sub-Contract Principal Investigator. National Heart, Lung and Blood Institute. Sep 2006 - Aug 2011. #RO1 HL53392-06A1.

    A photo of Gary Webb.

    Gary D. Webb, MD
    Director, Cincinnati Adolescent and Adult Congenital Heart Disease Program

    513-803-1777

    gary.webb@cchmc.org

    A photo of Gary Webb.
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    Gary D. Webb, MD

    Director, Cincinnati Adolescent and Adult Congenital Heart Disease Program

    Professor, UC Department of Pediatrics

    Phone: 513-803-1777

    Fax: 513-803-1778

    Email: gary.webb@cchmc.org

    Show All

    Specialties

    Adult congenital heart disease and Marfan syndrome
     

    Biography

    Gary D. Webb, MD, is a professor of pediatrics and internal medicine at the University of Cincinnati College of Medicine. He is director of the Adolescent and Adult Congenital Heart Program at Cincinnati Children's Hospital Heart Institute. 

    After receiving a BSC and MDCM from McGill University in Montréal, Québec, he went on to intern at the Royal Victoria Hospital in Montréal, and then to training in internal medicine and cardiology at the University of Toronto. After 8 years as chief of cardiology at the Wellesley Hospital in Toronto, he moved back to Toronto General Hospital. 

    Beginning in 1980, he was co-director and then director of the Toronto Congenital Cardiac Center for Adults. For several years, he directed the adult cardiology training program at the University of Toronto. He is a fellow of the Royal College of Physicians and Surgeons of Canada in both internal medicine and cardiology. He is a fellow of the American College of Cardiology, and a life member of the European Society of Cardiology. 

    In 2004, he relocated to Philadelphia, serving as director of the Philadelphia Adult Congenital Heart Center at the University of Pennsylvania. In 2009, he took up his current position at Cincinnati Children's Hospital.

    Education and Training

    MD: McGill University, Montréal, Québec, 1967.

    Residency: Internal medicine and cardiology, University of Toronto, Toronto Ontario, Canada.

    Fellowship: Royal College of Physicians and Surgeons of Canada (Cardiology), 1972;  Royal College of Physicians and Surgeons of Canada (Internal Medicine), 1972; Fellow of the American College of Cardiology, 1976.  

    Publications

    View PubMed Publications

    Cardiothoracic Surgery

    A photo of David Morales.

    David L. S. Morales, MD
    Chief of Cardiovascular Surgery, The Heart Institute, Cardiothoracic Surgery

    513-803-9150

    david.morales@cchmc.org

    A photo of David Morales.
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    David L.S. Morales, MD

    Chief of Cardiovascular Surgery, The Heart Institute, Cardiothoracic Surgery

    Co-Executive Director, The Heart Institute

    Clark-Helmsworth Chair of Cardiovascular Surgery

    Professor, UC Department of Pediatrics

    Professor, UC Division of Surgery

    Phone: 513-803-9150

    Email: david.morales@cchmc.org

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    Specialties

    Clinical Interests

    Congenital heart surgery; heterotaxy syndrome; pediatric heart and lung transplantation; mechanical circulatory support

    Research Interests

    Clinical and translational research related to mechanical circulatory support and tissue engineering

    Education and Training

    MD: Yale University School of Medicine, New Haven, CT.

    Residency: General and cardiothoracic surgery, New York-Presbyterian Medical Center, Columbia University, New York, NY.

    Fellowships: Congenital heart surgery, Texas Children’s Hospital, Baylor University, Waco, TX.

    Board certifications: Surgery, thoracic surgery, congenital heart surgery.

    A photo of Vincent F. Olshove.

    Vincent F. Olshove, CCP, FPP
    Director, Cardiovascular Perfusion, Chief Perfusionist

    513.636.4770

    vincent.olshove@cchmc.org

    DefaultUser

    Vincent F. Olshove, CCP, FPP

    Director, Cardiovascular Perfusion, Chief Perfusionist

    Clinical Instructor, Heart Institute

    Phone: 513.636.4770

    Email: vincent.olshove@cchmc.org

    Show All

    Specialties

    Clinical

    Pediatric cardiopulmonary bypass and support techniques; circuit miniaturization; bloodless cardiac surgical techniques

    Research

    Pediatric cardiopulmonary bypass and support techniques; circuit miniaturization; bloodless cardiac surgical techniques; role of ATIII in inflammatory response

    Publications


    A photo of Dr. Alistair Phillips.

    Alistair B. M. Phillips, MD, FACC, FACS
    Surgical Director, Pediatric Heart Transplantation and Mechanical Circulatory Support

    513-636-1349

    alistair.phillips@cchmc.org

    A photo of Dr. Alistair Phillips.
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    Alistair B.M. Phillips, MD, FACC, FACS

    Surgical Director, Pediatric Heart Transplantation and Mechanical Circulatory Support

    Surgical Director, Adult Congenital Heart Disease

    Associate Professor, Division of Pediatric Surgery

    Phone: 513-636-1349

    Email: alistair.phillips@cchmc.org

    Show All

    Specialties

    Congenital heart disease including adult congenital heart disease and "hybrid" approaches to congenital heart disease; heart transplantation and mechanical circulatory support

    Biography

    Alistair B. M. Phillips, MD, FACC, FACS, is an attending surgeon at Cincinnati Children’s Hospital Medical Center. Dr. Phillips received his undergraduate degree from The Johns Hopkins University and his medical degree from The College of Physicians & Surgeons of Columbia University.

    After completing general and cardiothoracic surgery, as well as two years of research generally focused on cardiac physiology at New York Presbyterian – Cornell Medical Center, Dr. Phillips went onto New York Presbyterian – Columbia Medical Center were he completed fellowships in pacemakers/ defibrillators and pediatric cardiac surgery.

    Dr. Phillips is board-certified in both surgery and thoracic surgery. His clinical interests are in congenital heart disease, including adult congenital heart disease, heart and lung transplantation, and electrophysiology. He is also interested in developing novel approaches to treating congenital heart disease mainly through a hybrid approach.

    Dr. Phillips is actively involved in research with particular interests in inflammation and post-operative arrhythmias, understanding right ventricular morphology and the relationship of the cardiopulmonary systems. Dr. Phiillips has spent the last couple years developing a translational research team with emphasis on improve the quality of care for our patients and improving long-term outcomes.

    Dr. Phillips major achievements over the past 5 years are developing the adult congenital surgical program in Columbus, including an aortic aneurysm program. He started the ventricular assist device program at Nationwide Children’s Hospital, as well as a pediatric thoracic program. Dr. Phillips is currently the Surgical Director of Heart Transplant and Mechanical Circulatory Support, and Surgical Director of Adult Congenital Heart Disease at Cincinnati Children’s.

    Education and Training

    MD: College of Physicians & Surgeons of Columbia University, New York, NY, 1994

    Residency: Surgical Intern, Department of Surgery, The New York Hospital, New York, NY, July 1994 - June 1995.

    Publications

    View PubMed Publications

    Grants

    Development and study of novel epicardial pacing lead. Principal Investigator. Medtronic. Dec 2010 - Aug 2011.

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