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Meet the team members of the Heart Institute's Cardiology Clinic at Cincinnati Children's Hospital Medical Center.
Andrew Redington, MD Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology firstname.lastname@example.org
Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology
Professor, UC Department of Pediatrics
Dr. Redington comes to Cincinnati Children’s from The Hospital for Sick Children in Toronto, Ontario. His research interests include ventricular function, integrated physiology of congenital heart disease, and ischemic preconditioning. Dr. Redington has written more than 300 peer-reviewed publications, more than 30 book chapters, and has co-edited seven textbooks. He currently holds over 15 US and international patents.
Working with colleagues throughout the Heart Institute, his plans include building on the remarkable developments achieved in the recent past to establish a world-leading multidisciplinary team providing the highest quality clinical care and practice-changing research for children and adults with congenital heart disease.
Medical School: University of London.
Research Training: Doctorate of Medicine, University of London.
Fellowship: Adult cardiology, pediatric cardiology, The Royal Brompton Hospital, London, England.
Li J, Rohaila S, Gelber N, Rutka J, Sabah N, Gladstone R, Wei C, Kharbanda R, Redington AN. MicroRNA-144 is a circulating effector of remote ischemic preconditioning. Basic Research in Cardiology 2014: 109 (5): pp 423. (Sept)
Burns KM, Byrne BJ, Gelb BD, Kuhn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN. New mechanistic and therapeutic targets for pediatric heart failure: report from a national heart, lung, and blood institute working group. Circulation 2014: 130 (1): pp 79-86. (July)
Friedberg MK, Redington AN. Right versus left ventricular failure: differences, similarities, and interactions. Circulation 2014: 129 (9): pp 1033-1044. (Mar)
Friedberg MK, Cho MY, Li J, Assad RS, Sun M, Rohailla S, Honjo O, Apitz C, Redington AN. Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased TGFβ1 signaling and is abrogated by angiotensin receptor blockade. American Journal of Respirology Cell Molecular Biology 2013: 49 (6): pp 1019-1028. (Dec)
Roche SL, Redington AN. Right ventricle: wrong targets? Another blow for pharmacotherapy in congenital heart diseases. Circulation 2013: 127 (3): pp 314-316. (Jan)
Hahn CD, Manlhiot C, Schmidt MR, Nielsen TT, Redington AN. Remote ischemic per-conditioning: A novel therapy for evolving stroke? Stroke 2011: 42 (10) pp 2960-2962.
Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Slievert G, Wells GD, Redington AN. Remote Ischemic Preconditioning improves maximal performance in elite athletes. Medicine & Science of Sports & Exercise 2011: 43 (7): pp 1280-1286.
Wei M, Xin P, Li Y, Li J, Ma S, Wang L, Liu M, Li J, Zhu W, Redington AN. Repeated remote ischemic postconditioning protects against adverse left ventricular remodeling and improves survival in a rat model of myocardial infarction. Circulation Research 2011: 108 (10): pp 1220-1225.
Roche SL, Vogel M, Pitkanen O, Grant B, Slorach C, Fackoury C, Stephens D, Smallhorn J, Benson LN, Kantor PF, Redington AN. Isovolumic acceleration at rest and during exercise in children normal values for the left ventricle and first non-invasive demonstration of exercise-induced force-frequency relationships. Journal of American College of Cardiology 2011: 57 (9): pp 1100-1107.
Botker HE, Kharbanda R, Schmidt MR, Bottcher M, Kaltoft AK, Terkelsen CJ, Munk K, Anderson NH, Hansen TM, Trautner S, Lassen JF, Christiansen EH, Krusell LR, Kristensen SD, Thuesen L, Nielsen SS, Rehling M, Sorensen HT, Redington AN, Neilseu TT: Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomized trial. Lancet 2010: 375 (9716): pp 727-734.
Thomas R. Kimball, MD Medical Director, Heart Institute 513-636-8270 email@example.com
Medical Director, Heart Institute
Congential heart disease; echocardiography; cardiac imaging
Thomas R. Kimball, MD, is a professor of pediatrics with the University of Cincinnati College of Medicine and is currently the medical director of the Heart Institute at Cincinnati Children's Hospital Medical Center.
A native of California, Dr. Kimball graduated with distinction and honors from Stanford University. He earned his medical degree from New York University, New York, NY. He completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center.
Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988.
Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.
He has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.
Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network.
He was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.
In 2010, he was made the medical director of the Heart Institute at Cincinnati Children's.
BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.
MD: New York University School of Medicine, New York City, NY, 1982.
Residency: Children's Hospital of Los Angeles, Los Angeles, CA, 1985.
Fellowship: Children's Hospital Medical Center, Cincinnati, OH, 1988.
Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).
Shah AS, Gao Z, Urbina EM, Kimball TR, Dolan LM. The effects of arterial thickness and stiffness in obese youth. Journal of Clinical Endocrinology Metabolism. 2014 Mar;99(3):1037-43.
Alghamdi M, De Souza AM, White CT, Potts MT, Warady BA, Furth SL, Kimball TR, Potts JE, Sandor GG. Response to: echocardiography assessment of the aorta in children with chronic kidney disease. Pediatric Cardiology. 2014 Jan;35(1):183-4.
Uzark K, King E, Spicer R, Beekman R, Kimball T, Varni J. The clinical utility of health-related quality of life assessment in pediatric cardiology outpatient practice. Congenital Heart Disease. 2013 May;8(3):211-8.
Madueme PC, Khoury PR, Urbina EM, Kimball TR. Predictors of exaggerated exercise-induced systolic blood pressures in young patients after coarctation repair. Cardiology In The Young. 2013 Jun;23(3):416-22.
Alghamdi M, De Souza A, White CT, Potts MT, Warady BA, Furth SL, Kimball T, Potts JE, Sandor GG. Echo-Doppler assessment of the biophysical properties of the aorta in children with chronic kidney disease. Pediatric Cardiology. 2013 Jun;34(5):1218-25.
Urbina EM, Khoury PR, McCoy CE, Dolan LM, Daniels SR, Kimball TR. Triglyceride to HDL-C ratio and increased arterial stiffness in children, adolescents and young adults. Pediatrics. 2013 Apr;131(4):E1082-90.
Shah AS, Urbina EM, Khoury PR, Kimball TR, Dolan LM. Lipids and lipoprotein ratios: Contribution to carotid intima media thickness in adolescents and young adults with type 2 diabetes mellitus. Journal of Clinical Lipidology. 2013 Sept-Oct;7(5):441-445.
Kimball TR. Echocardiography in the Assessment of Cardiovascular Disease Risk. In: Eduardo M. da Cruz, Dunbar Ivy, James Jaggers, editors, Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care. Springer-Verlag London 2013. ISBN:978-1-4471-4618-6.
Kimball TR, Michelfelder EC. Echocardiography: Basic Principles and Imaging. In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, editors. Moss & Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. 1. Philadelphia, PA: Lippincott Williams & Wilkins; 2012. p. 134-71.
Shah AS, Dolan LM, Gao Z, Kimball TR, Urbina EM. Racial differences in arterial stiffness among adolescents and young adults with type 2 diabetes. Pediatric Diabetes. 2012 Mar;13(2):170-5.
Jeffrey B. Anderson, MD, MPH, MBA Chief Quality Officer, Heart Institute 513-636-3865 firstname.lastname@example.org
Chief Quality Officer, Heart Institute
Associate Professor, UC Department of Pediatrics
Pediatric electrophysiology; syncope; quality improvement and outcomes
Following his cardiology fellowship, Dr. Anderson helped establish the Syncope Clinic in the Heart Institute at Cincinnati Children’s Hospital Medical Center, and he continues to direct the work in this clinic.
Dr. Anderson helped develop the Safety, Quality, Value program within the Heart Institute at Cincinnati Children's Hospital Medical Center. The Heart Institute’s Safety, Quality, and Value team provides a platform of core data management, analytic, quality improvement, and project management expertise focused specifically on the Heart Institute’s strategic priority areas related to safety, quality, and value. This team serves a supporting role to further the Heart Institute’s ability to achieve its mission of being the leader in clinical outcomes, experience, and value for patients and families who receive diagnostic and interventional services for congenital and acquired heart disease.
MD: University of Utah School of Medicine, Salt Lake City, UT, 2002.
Masters of Public Health: University of Utah School of Medicine, Salt Lake City, UT, 2002.
Residency: Pediatrics, University of North Carolina,Chapel Hill, NC, 2002-2006.
Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2006-2009.
Fellowship: Pediatric Electrophysiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009-2010.
Masters of Business Administration: Ross School of Business, University of Michigan, Ann Arbor, MI, 2013.
Anderson J, Grenier M, Edwards N, Madsen N, Czosek R, Spar D, Barnes A, Pratt J, King E, Knilans T.Usefulness of Combined History, Physical Examination, Electrocardiogram and Limited Echocardiogram in Screening Adolescent Athletes for Risk for Sudden Cardiac Death. Am J Cardiol. 2014 Dec 1;114(11):1763-7.
Anderson JB, Beekman RH 3rd, Kugler JD, Rosenthal GL, Jenkins KJ, Klitzner TS, Martin GR, Neish SR, Darbie L, King E, Lannon C. Improvement in growth in infants with single ventricle using a learning collaborative. National Pediatric Cardiology Quality Improvement Collaborative. Congenit Heart Dis. 2014 Nov;9(6):512-20.
Burch PT, Gerstenberger E, Ravishankar C, Hehir DA, Davies RR, Colan SD, Sleeper LA, Newburger JW, Clabby ML, Williams IA, Li JS, Uzark K, Cooper DS, Lambert LM, Pemberton VL, Pike NA, Anderson JB, Dunbar-Masterson C, Khaikin S, Zyblewski SC, Minich LL. Longitudinal assessment of growth in hypoplastic left heart syndrome: results from the single ventricle reconstruction trial. J Am Heart Assoc. 2014 Jun 27;3(3).
Slicker J, Hehir DA, Horsley M, Monczka J, Stern KW, Roman B, Ocampo EC, Flanagan L, Keenan E, Lambert LM, Davis D, Lamonica M, Rollison N, Heydarian H, Anderson JB. Nutrition Algorithms for Infants with Hypoplastic Left Heart Syndrome; Birth Through the First Interstage Period. Congenital Heart Disease. 2013 Mar-April;8(2)89-102.
Anderson JB, Czosek RJ, Knilans TK, Marino BS.The Effect of Paediatric Syncope on Health-Related Quality of Life. Cardiol Young. 2012 Oct;22(5):583-588.
Anderson J, Czosek R, Cnota J, Meganathan K, Knilans T, Heaton P. Pediatric syncope: National Hospital Ambulatory Medical Care Survey results. J Emerg Med. 2012 Oct;43(4):575-83.
Anderson J, Iyer S, Schidlow D, Williams R, Varadarajan K, Horsley M, Slicker J, Pratt J, King E, Lannon C. Variation in growth of infants with a single ventricle. J Pediatr. 2012 Jul;161(1):16-21.
Anderson J, Eghtesady P, Kalkwarf HJ, Kehl JE, Marino BS. Low weight-for-age z-score and infection risk following Fontan procedure. Ann Thorac Surg. 2011 May;91(5):1460-6.
Anderson J, Beekman RH, Eghtesady P, Uzark K, Kalkwarf HJ, Kehl JE, Marino BS.Predictors of poor weight gain in infants with a single ventricle. J Pediatr. 2010 Sep;157(3):407-13, 413.e1.
Anderson JB, Beekman RH, 3rd, Border WL, Kalkwarf HJ, Khoury PR, Uzark K, Eghtesady P, Marino BS. Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle. J Thorac Cardiovasc Surg. 2009;138(2):397-404.
Clifford Chin, MD Co-Director, Advanced Cardiomyopathy Services, Heart Institute 513-803-3151 email@example.com
Co-Director, Advanced Cardiomyopathy Services, Heart Institute
Pediatric cardiology; cardiomyopathy and transplantation
MD: SUNY Downstate Medical Center, Brooklyn, NY, 1989.
Residency: Pediatrics, University of California Davis Medical Center, Sacramento, CA, 1989.
Fellowship: Stanford University, Stanford, CA, 1992.
Castleberry C, Ryan T, Chin C. Transplantation in the Highly Sensitized Pediatric Patient. Circulation. 2014;129:2313-2319.
Chin C. Pediatric Antibody Mediated Rejection. Pediatric Transplantation. 2012;16:404-4012.
Pietra B, Kantor P, Bartlett H, Chin C, Canter C, Larsen R, Edens E, Colan C, Towbin T, Lipshultz S, Kirklin J, Naftel D, Sleeper L, Hsu D. Early Predictors of Survival to and After Clinical Heart Transplantation in Children’ with Dilated Cardiomyopathy. Circulation. 2012;126:1079-86.
Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Reinhartz O, Tyan D. Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. J Heart Lung Transplant. 2011 Feb;30(2):158-63.
Chin C, Lukito SS, Shek J, Bernstein D, Perry SB. Prevention of pediatric graft coronary artery disease: atorvastatin. Pediatr Transplant. 2008 Jun;12(4):442-6.
Potena L, Fearon WF, Sydow K, Holweg C, Luikart H, Chin C, Weisshaar D, Mocarski ES, Lewis DB, Valantine HA, Cooke JP. Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation. 2008 Mar 27;85(6):827-33.
Tu W, Potena L, Stepick-Biek P, Liu L, Dionis KY, Luikart H, Fearon WF, Holmes TH, Chin C, Cooke JP, Valantine HA, Mocarski ES, Lewis DB. T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease Circulation. 2006 Oct 10;114(15):1608-15.
Potena L, Holweg CT, Chin C, Luikart H, Weisshaar D, Narasimhan B, Fearon WF, Lewis DB, Cooke JP, Mocarski ES, Valantine HA. Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation. 2006 Aug 15;82(3):398-405.
Chin C, Naftel D, Pahl E, Shankel T, Clark ML, Gamberg P, Kirklin J, Webber S; Pediatric Heart Transplant Study. Cardiac re-transplantation in pediatrics: a multi-institutional study. J Heart Lung Transplant. 2006 Dec;25(12):1420-4.
Chin C, Naftel DC, Singh TP, Blume ED, Luikart H, Bernstein D, Gamberg
P, Kirklin JK, Morrow WR, Pediatric Heart Transplant Study Group. Risk
factors for recurrent rejection in pediatric heart transplantation: a
multicenter experience. J Heart Lung Transplant. 2004 Feb;23(2):178-85.
David S. Cooper, MD, MPH Chief Safety Officer, Heart Institute 513-803-5448 firstname.lastname@example.org
Chief Safety Officer, Heart Institute
Associate Medical Director, Cardiovascular Intensive Care Unit
Co-Director, Center for Acute Care Nephrology
Medical Director, Cardiac Extracorporeal Life Support Program
Pediatric cardiac critical care; patient safety; extracorporeal life support
Dr. Cooper is board certified in Pediatrics, Pediatric Cardiology and Pediatric Critical Care. He is currently the Heart Institute Safety Officer, Co-Director of the Center for Acute Care Nephrology, Director of the Cardiac ECMO Program and Associate Medical Director of the CICU at Cincinnati Children’s Hospital Medical Center.
Dr. Cooper's career over the past 10 years has focused on the care of critically ill neonates, infants, children, adolescents and adults with complex congenital heart disease (CHD). He has a particular interest in how care in the intensive care unit can impact morbidity with a specific interest in hematologic, infectious and renal morbidities. Additionally, Dr. Cooper has had extensive involvement with the Pediatric Cardiac Critical Care Consortium (PC4), including the development of the PC4 CICU database that will be used to track outcomes and improve outcomes for patients with critical cardiac disease.
MD: University of South Florida College of Medicine, Tampa, Florida, 1996.
MPH: University of South Florida College of Public Health, Tampa, Florida, 1999.
Residency: All Children’s Hospital, University of South Florida, St. Petersburg, FL.
Fellowships: Cardiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; Critical Care, Children’s Medical Center Dallas, UT Southwestern, Dallas, Texas.
Certifications: American Board of Pediatrics; American Board of Pediatrics, Sub-board of Pediatric Cardiology; American Board of Pediatrics, Sub-board of Pediatric Critical Care.
DeSena HC, Nelson DP, Cooper DS. Cardiac Intensive Care for the Neonate and Child After Cardiac Surgery. Current Opinion in Cardiology. 2015 Jan;30(1):81-8.
Kwiatkowski DM, Menon S, Krawczeski CD, Goldstein SL, Morales DL, Philips A, Manning PB, Eghtesady P, Wang Y, Nelson DP, Cooper DS. Improved Outcomes with Peritoneal Dialysis Catheter Placement after Cardiopulmonary Bypass in Infants. Journal of Thoracic and Cardiovascular Surgery. 2015 Jan;149(1):230-6.
Gaies M, Cooper DS, Tabbutt S, Schwartz SM, Ghanayem N, Chanani NK, Costello JM, Thiagarajan RR, Laussen PC, Shekerdemian LS, Donohue JE, Willis GM, Gaynor JW, Jacobs JP, Ohye RG, Charpie JR, Pasquali SK, Scheurer MA. Collaborative quality improvement in the cardiac intensive care unit: development of the Paediatric Cardiac Critical Care Consortium (PC4). Cardiol Young. 2014 Aug;28:1-7.
Jolley M, Thiagarajan R, Salvin J, Barrett C, Cooper DS, Teele S. ECMO in Patients with Superior Cavopulmonary Anastomosis (Glenn). Journal of Thoracic and Cardiovascular Surgery. 2014;148(4):1512-8.
Costello JM, Pasquali SK, He X, Jacobs JP, Hill KD, Cooper DS, Baker CL, Jacobs ML. Gestational Age at Birth and Outcomes after Neonatal Cardiac Surgery: An Analysis of the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database. Circulation. 2014;129:2511-2517.
Tabbutt S, Ghanayem N, Ravishankar C, Sleeper LA, Cooper DS, Frank DU, Lu M, Pizarro C, Frommelt P, Goldberg CS, Graham EM, Krawczeski CD, Lai WW, Lewis A, Kirsh JA, Mahony L, Ohye RG, Simsic J, Lodge AJ, Spurrier E, Stylianou M, Laussen P, Pediatric Heart Network Investigators. Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012 Oct;144(4):882-95.
Ghanayem NS, Allen KR, Tabbutt S, Atz AM, Clabby ML, Cooper DS, Eghtesady P, Frommelt PC, Gruber PJ, Hill KD, Kaltman JR, Laussen PC, Lewis AB, Lurito KJ, Minich LL, Ohye RG, Schonbeck JV, Schwartz SM, Singh RK, Goldberg CS, Pediatric Heart Network Investigators. Interstage mortality after the Norwood procedure: Results of the multicenter Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012 Oct;144(4):896-906.
Cooper DS, Charpie JR, Flores FX, Gaynor JW, Salvin JW, Devarajan P, Krawczeski CD. Acute kidney injury and critical cardiac disease. World J Ped Congen Heart Surg. 2011;2:411-423.
Jacobs JP, Asante-Korang A, O'Brien SM, Chai PJ, Dadlani GH, Rodriguez-Fazzi GL, Vu D, McCormack J, McKenna DE, Boucek RJ Jr, Cooper DS, Saltiel A, Carapellucci J, van Gelder HM, Daicoff GR, Quintessenza JA. Lessons learned from 119 consecutive cardiac transplants for pediatric and congenital heart disease. Ann Thorac Surg. 2011 Apr;91(4):1248-54.
Pilchard J, Dadlani G, Andropoulos D, Jacobs JP and Cooper DS. Intensive care and perioperative management of patients with complete atrioventricular septal defect. World J Ped Congen Heart Surg. 2010 Apr;1:105-111.
Evaluation of the Pharmacokinetics of ATIII in Neonates and Infants Undergoing CPB and ECMO Support. Principal Investigator. Grifols. 2014-present.
A Randomized, Placebo Controlled, Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Intravenous (IV) Acetaminophen for the Treatment of Acute Pain in Pediatric Patients. Site Principal Investigator. Cadence. 2014-present.
Use of acute kidney injury biomarkers to predict impaired milrinone pharmacokinetics in children. Mentor. Thrasher grant. 2013-present.
Extracorporeal Life Support Organization (ELSO) Research Grant. Principal Investigator. Extracorporeal Life Support Organization. 2012-present.
Haleh C. Heydarian, MD Cardiologist, Cardiology Clinic 513-636-6646
Cardiologist, Cardiology Clinic
Assistant Professor, UC Department of Pediatrics
MD: Marshall University, Huntington, WV.
Residency: Pediatrics, Nationwide Children’s Hospital, Columbus, OH.
Fellowship: Cincinnati Children’s Hospital, Cincinnati, OH.
Russel Hirsch, MD Director, Cardiac Catheterization Laboratory 513-636-7072
Director, Cardiac Catheterization Laboratory
Director, Pulmonary Hypertension Service
Percutaneous interventions for the palliation or treatment of congenital heart disease; treatment of all forms of pediatric pulmonary hypertension
MBChB: University of Cape Town, Cape Town, South Africa.
Residency: St. Louis Children's Hospital, St. Louis, MO.
Fellowship: St. Louis Children's Hospital and Washington University School of Medicine, St. Louis, MO.
Certification: Pediatrics, 1994, 2002 (renew); Pediatric Cardiology, 1998, 2005.
Flores S, Daily J, Pratap JN, Cash MC, Hirsch R. Management of a child with pulmonary arterial hypertension presenting with a systemic hypertension. Cardiol Young. 2015 Jun 17;1-4.
Seckeler M, Hirsch R, Beekman R, Goldstein B. A new predictive equation for oxygen consumption in children and adults with congenital and acquired heart disease. Heart. 2015 Apr;101(7):517-24.
Dandoy C, Davies S, Hirsch R, Chima R, Paff Z, Cash M, Ryan T, Lane A,El-Bietar J, Myers K, Jodele S. Abnormal echocardiography seven days after stem cell transplant may be an early indicator of thrombotic microangiopathy. Biology of Blood and Marrow Transplantation. 2015 Jan;21(1):113-8.
Aiyagari R, Rhodes JF, Shrader P, Radtke W, Bandisode VM, Bergersen L, Gillespie MJ, Gray RG, Guey LT, Hill KD, Hirsch R, Kim DW, Lee KJ, Pelech A, Ringewald J, Takao C, Vincent JA, Ohye RG. Impact of Pre-Stage II Hemodynamics and Pulmonary Artery Anatomy on 12-Month Outcome in the Single Ventricle Reconstruction Trial. The Journal of Thoracic and Cardiovascular Surgery. 2014 Oct;148(4):1467-74.
Zussman M, Hirsch R, Beekman R, Goldstein B. Impact of percutaneous interventions for pulmonary artery stenosis in Alagille syndrome. Congenital Heart Disease. 2014 Sep 16.
Seckeler MD, Hirsch R, Beekman RH 3rd, Goldstein BH.Validation of cardiac output using real-time measurement of oxygen consumption during cardiac catheterization in children under 3 years of age. Congenit Heart Dis. 2014 Jul-Aug;9(4):307-15.
Seckeler M, Villa C, Hirsch R. Percutaneous Recanalization
of Occluded Brachiocephalic Vein-Superior Vena Cava Connection After
Resection of Mediastinal Mass.JACC Intervention. 2014 Jul;7(7):e69-70.
Dandoy C, Lerner D, Hirsch R, Laskin B, Davies
S, Jodele S.Pericardial Effusion in Pediatric Stem Cell
Transplant Recipients with Thrombotic Microangiopathy. Bone Marrow
Transplantation. 2014 Jun;862–863.
Lorts A, Hirsch R. Development and recognition of
cardiopulmonary complications in a child with cirrhosis: The heart in
chronic liver disease. Clinical Liver Disease. 2013 Oct 30;(2):207-209.
Dandoy C, Hirsch R, Chima R, Davies SM, Jodele S. Pulmonary Hypertension after Hematopoietic Stem Cell Transplant. Biol Blood Marrow Transplant. 2013 Nov;19(11):1546-1556.
Jeanne M. James, MD 513-803-3151 email@example.com
Cardiovascular genetics; echocardiography; congenital heart disease; medical education; molecular cardiology; ventricular remodeling; cardiac hypertrophy.
Visit the James Lab website.
Jeanne James, MD, is an associate professor of pediatrics at University of Cincinnati College of Medicine and is currently the director of the Cardiology Fellowship Training Program at Cincinnati Children's Hospital Medical Center.
A native of West Virginia, Dr. James earned her bachelor and medical degrees from West Virginia University in Morgantown, WV. She completed her pediatric residency and pediatric cardiology fellowship at Vanderbilt University Medical Center in Nashville, TN. Dr. James has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1995.
Dr. James' academic interests are in translational research on heart muscle disease, cardiovascular genetics and echocardiography. She has made numerous scholarly contributions to the field with publications describing both laboratory-based and clinical research. She serves as a grant reviewer for the American Heart Association and is a peer-reviewer for a number of scientific and medical journals.
Dr. James has established collaborative relationships with laboratory researchers at Cincinnati Children’s Hospital, the University of Cincinnati College of Medicine and investigators across the United States. As the director of the Mouse Echocardiography Core, she uses non-invasive imaging to evaluate phenotypes of transgenic mice, including embryonic mice.
Dr. James serves as an attending physician in clinical echocardiography laboratory as well as the inpatient cardiology ward and consult team. Dr. James is a member of the Cardiovascular Genetics (CVG) service and has significant responsibilities in the CVG outpatient clinic. Dr. James is a member of the American Society of Echocardiography, the American Heart Association and the Society for Pediatric Research.
MD: West Virginia University, Morgantown, WV, 1987.
Residency: Vanderbilt University Medical Center, Nashville, TN, 1987-90.
Fellowship: Vanderbilt University Medical Center, Nashville, TN, 1991-94.
Certification: Pediatrics, 1990 - present.
Certified: Pediatric Cardiology, 1996 - present.
Cheek J, Wirrig E, Alfieri C, James J, Yutzey K. Differential activation of valvulogenic, chondrogenic and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease. J Mol Cell Cardio. 2012 Mar;52(3):689-700.
Sadayappan S, Gulick J, Martin L, Osinska H, Barefield D, Cuello F, Avkiran M, Lasko V, Lorenz J, Maillet M, Martin J, Heller-Brown J, Bers D, Molkentin J, James J, Robbins J. A critical function for Ser-282 in cardiac myosin binding protein-C phosphorylation and cardiac function. Circ Res. 2011; 109(2):141-50.
James J, Kinnett K, Ittenbach R, Wang Y, Benson D, Cripe L. Electrocardiographic abnormalities in very young Duchenne muscular dystrophy patients precede the onset of cardiac dysfunction. Neuromuscul Disord. 2011; 21(7):462-7.
Combs M, Braitsch C, Lange A, James J, Yutzey K. NFATc1 promotes epicardium-derived cell (EPDC) invasion into myocardium. Development. 2011; 138(9):1747-57.
James J, Robbins J. Signaling and myosin binding protein C. J Biol Chem. 2011;286(12):9913-9.
Stanley BA, Graham DR, James J, Mitsak M, Tarwater PM, Robbins J, Van Eyk JE. Altered myofilament stoichiometry in response to heart failure in a cardioprotective a-myosin heavy chain transgenic rabbit model. Proteomics Clin Appl. 2011; 5(3-4):147-58.
Acehan D, Vaz F, Houtkooper R, James J, Moore V, Tokunaga C, Kulik W, Wansapura J, Toth M, Strauss A, Khuchua Z. Cardiac and skeletal muscle defects in a mouse model of human Barth syndrome. J Biol Chem. 2010; 286(2):899-908.
Hinton R, Adelman-Brown J, Witt S, Krishnamurthy V, Gruber M, Osinska H, Sakthivel B, James J, Narmoneva D, Mecham R, Benson D. Elastin haploinsufficiency results in latent progressive aortic valve disease in a mouse model. Circ Res. 2010; 107(4):549-57.
James J, Hor K, Moga M, Martin L, Robbins J. Effects of myosin heavy chain manipulation in experimental heart failure. J Mol Cell Cardiol. 2010; 48(5):999-1006.
Suzuki T, Palmer B, James J, Wang Y, Chen V, VanBuren P, Maughan D, Robbins J, LeWinter M. Effects of cardiac myosin isoform variation on myofilament function and cross-bridge kinetics in transgenic rabbits. Circ Heart Fail. 2009; 2(4):334-41.
Pattison J, Waggoner J, James J, Martin L, Gulick J, Osinska H, Klevitsky R, Kranias E, Robbins J. Phospholamban overexpression in transgenic rabbits. Transgenic Research. 2008; 17(2):157-70.
John Lynn Jefferies, MD, MPH, FAAP, FACC Director, Advanced Heart Failure and Cardiomyopathy 513-803-1675 firstname.lastname@example.org
Director, Advanced Heart Failure and Cardiomyopathy
Dr. Jefferies, an associate professor of pediatric cardiology and adult cardiovascular diseases within the University of Cincinnati College of Medicine, is the director of Advanced Heart Failure / Cardiomyopathy in the Heart Institute at Cincinnati Children's Hospital Medical Center.
He completed his combined pediatric and adult cardiology training at the Baylor College of Medicine in Houston, Texas at the Texas Children's Hospital and the Texas Heart Institute. He has authored or co-authored over 120 peer-reviewed manuscripts and book chapters on cardiomyopathy, cardiovascular genetics, and adults with congenital heart disease.
His current research interests include heritable causes of cardiovascular disease, novel drug therapies for advanced heart failure, novel gene discovery in cardiomyopathy, characterization and management of left ventricular noncompaction (LVNC), and early diagnosis and management of chemotherapy induced cardiotoxicity.
He is on the editorial board of the Texas Heart Institute Journal and is an active member of numerous professional organizations, including the Heart Failure Society of America, the American College of Cardiology and the American Heart Association. He is the lead editor for two textbooks that focus on the management of heart disease in children and young adults entitled “Heart Failure in the Child and Young Adult: From Bench to Bedside” and “Cardioskeletal Myopathies in Children and Young Adults.”
BS: University of Tennessee, Knoxville, TN, 1992.
MD: University of Tennessee, Knoxville, TN, 1996.
Residency: University of Kentucky, Lexington, KY, 2000.
MPH: University of Kentucky, Lexington, KY, 2001.
Fellowship: Baylor College of Medicine, Houston, TX, 2006.
Certification: Pediatrics, Internal Medicine, Cardiology, Advanced Heart Failure, Cardiac Transplant.
Towbin JA, Lorts A, Jefferies JL. Left ventricular noncompaction cardiomyopathy. Lancet. 2015;Apr 9. Epub ahead of print.
McCullough PA, Jefferies JL. Novel Markers And Therapies For Patients With Acute Heart Failure And Renal Dysfunction. Am J Med. 2015 Mar;128(3):312.e1-22.
Villa CR, Ryan TD, Collins JJ, Taylor MD, Lucky AW, Jefferies JL. Left ventricular non-compaction cardiomyopathy associated with epidermolysis bullosa simplex with muscular dystrophy and PLEC1 mutation. Neuromuscul Disord. 2015 Feb;25(2):165-8.
Raman SV, Hor KN, Halnon NJ, Kissel JT, He X, Tran T, Smart S, McCarthy B, Taylor MD, Jefferies JL, Rafael-Fortney JA, Lowe J, Roble SL, Cripe LH. Eplerenone for early cardiomyopathy in Duchenne muscular dystrophy: a randomised, double-blind, placebo-controlled trial. Lancet Neurol. 2015 Feb;14(2):153-61.
Jefferies JL. Barth syndrome. Am J Med Genet C Semin Med Genet. 2013 Aug;163C(3):198-205.
Breinholt JP, Moulik M, Dreyer WJ, Denfield SW, Kim JJ, Jefferies JL, Rossano JW, Gates CM, Clunie SK, Bowles KR, Kearney DL, Bowles NE, Towbin JA. Viral epidemiologic shift in inflammatory heart disease: the increasing involvement of parvovirus B19 in the myocardium of pediatric cardiac transplant patients. J Heart Lung Transplant. 2010 Jul;29(7):739-46.
Carlson P, Jefferies JL, Kearney D, Russell H. Refractory dilated cardiomyopathy associated with metastatic neuroblastoma. Pediatr Blood Cancer. 2010 Jun 29.
Shah AM, Jefferies JL, Rossano JW, Decker JA, Cannon BC, Kim JJ. Electrocardiographic abnormalities and arrhythmias are strongly associated with the development of cardiomyopathy in muscular dystrophy. Heart Rhythm. 2010 Jun 18.
Rossano JW, Morales DL, Zafar F, Denfield SW, Kim JJ, Jefferies JL, Dreyer WJ. Impact of antibodies against human leukocyte antigens on long-term outcome in pediatric heart transplant patients: An analysis of the United Network for Organ Sharing database. J Thorac Cardiovasc Surg. 2010 May 26.
Timothy K. Knilans, MD Director, Clinical Cardiac Electrophysiology and Pacing 513-636-7269 email@example.com
Director, Clinical Cardiac Electrophysiology and Pacing
Cardiac electrophysiology and pacing; radio frequency ablation; tilt table testing
MD: University of Cincinnati, Cincinnati, OH, 1983.
Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1983-1986.
Fellowship (Pediatric Cardiology): Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1986-1989.
Fellowship (Cardiac Electrophysiology): St. Vincent Hospital, Indianapolis, IN, 1990-1991.
Fellowship (Pediatric cardiac Electrophysiology): Texas Children's Hospital, Houston, TX, 1991.
Certification: Pediatrics, 1989 (Recertified 1999); Pediatric Cardiology, 1992 (Recertified 1998).
Czosek RJ, Anderson JB, Marino BS, Mellion K, Knilans TK. Noninvasive risk stratification techniques in pediatric patients with ventricular preexcitation. Pacing Clin Electrophysiol. 2011 May;34(5):555-62.
Eghtesady P, Michelfelder EC, Knilans TK, Witte DP, Manning PB, Crombleholme TM. Fetal surgical management of congenital heart block in a hydropic fetus: Lessons learned from a clinical experience. J Thorac Cardiovasc Surg. 2011 Mar;141(3):835-7.
Czosek RJ, Anderson J, Marino BS, Connor C, Knilans TK. Linear lesion cryoablation for the treatment of atrioventricular nodal re-entry tachycardia in pediatrics and young adults. Pacing Clin Electrophysiol. 2010 Nov;33(11):1304-11.
Czosek RJ, Anderson JB, Cao J, Knilans TK. Assessment of T-wave oversensing in an infant with an implanted defibrillator. Heart Rhythm. 2010 Oct;7(10):1516-7.
Mays WA, Border WL, Knecht SK, Gerdes YM, Pfriem H, Claytor RP, Knilans TK, Hirsch R, Mone SM, Beekman RH 3rd. Exercise capacity improves after transcatheter closure of the Fontan fenestration in children. Congenit Heart Dis. 2008 Jul;3(4):254-61.
Knecht SK, Mays WA, Gerdes YM, Claytor RP, Knilans TK. Exercise evaluation of upper- versus lower-extremity blood pressure gradients in pediatric and young-adult participants. Pediatr Exerc Sci. 2007 Aug;19(3):344-8.
Wright KN, Knilans TK, Irvin HM. When, why, and how to perform cardiac radiofrequency catheter ablation. J Vet Cardiol. 2006 Nov;8(2):95-107.
Knilans TK. Multielectrode coronary artery catheterization: still an effective tool in ablation of right free-wall accessory pathways. J Cardiovasc Electrophysiol. 2004 Nov;15(11):1244-5.
Markham LW, Knecht SK, Daniels SR, Mays WA, Khoury PR, Knilans TK. Development of exercise-induced arm-leg blood pressure gradient and abnormal arterial compliance in patients with repaired coarctation of the aorta. Am J Cardiol. 2004 Nov 1;94(9):1200-2.
Beery TA, Dyment M, Shooner K, Knilans TK, Benson DW. A candidate locus approach identifies a long QT syndrome gene mutation. Biol Res Nurs. 2003 Oct;5(2):97-104.
Lisa A. Lee, MD Director, Community Based Cardiology, Heart Institute 859-344-4732 firstname.lastname@example.org
Director, Community Based Cardiology, Heart Institute
Pediatric cardiology; outpatient community based services
BA: Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 1989.
MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.
Residency: Cincinnati Children's Hospital, Cincinnati, OH, 1993-1996.
Fellowships: Pediatric Resident, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1994-1996; Pediatric Cardiology, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 1997-2000; Pediatric Echocardiography, Cincinnati Children's Hospital, Cincinnati, OH, 2000-2001.
Certification: Pediatrics, 1996; Pediatric Cardiology, 2000.
Lee LA. Innocent murmurs. Presented to the family practice residents and St. Elizabeth Medical Center, Edgewood, KY. January 10, 2003
Lee LA. Stress echocardiography in children. Pediatric Ultrasound Today. 2001 Volume 6, Lesson 4.
Lee LA, Goya G, Witt SA, Flascock BJ, Mays W, Kimball TR. Resting predictors of latent stress-induced left ventricular outflow tract obstruction in young patients with hypertrophic cardiomyopathy. J Am Coll Cardiology. 2001 Oct.
Lee LA. Evaluation and management of hypertension in children. Presented to nurse practitioner students, University of Michigan School of Nursing, Ann Arbor, MI. March 2000.
Lee LA, Simon C, Bove EL, Mosca RS, Ebbini ES, Abrams GD, Ludomirsky A. High-intensity focused ultrasound effect on cardiac tissues: potential for clinical application. Echocardiography. 2000 Aug; 17(6 Pt 1):563-6.
Ohye RG, Kagisaki K, Lee LA, Mosca RS, Goldberg CS, Bove EL. Biventricular repair for aortic atresia or hypoplasia and ventricular septal defect. J Thorac Cardiovasc Surg. 1999;118(4):648-53.
Lee LA, Kimball TR, Daniels SR, Khoury P, Meyer RA. Left ventricular mechanics in the preterm infant and their effect on the measurement of cardiac performance. J Pediatr. 1992 Jan;120(1):114-9.
Angela Lorts, MD Director, Ventricular Assist Device Program 513-803-4580 email@example.com
Director, Ventricular Assist Device Program
Heart failure; cardiopulmonary bypass mediated myocardial dysfunction; novel uses of pediatric VADs
MD: Creighton University Medical School, Omaha, NE, 1998.
Residency: The Children’s Hospital, Denver, CO, 2001.
Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2004; University of Michigan Medical Center, Ann Arbor, MI, 2006.
Certifications: American Board of Pediatrics, 2001; American Board of Pediatrics, Sub-Board of Pediatric Cardiology, 2004; American Board of Pediatrics, Sub-Board of Pediatric Critical Care, 2006.
Towbin JA, Lorts A, Jefferies JL. Left ventricular non-compaction cardiomyopathy. Lancet. 2015 Apr 9.
Benoit S, Antommaria AH, Weidner N, Lorts A. Difficult decision: what should we do when a VAD-supported child experiences a severe stroke? Pediatr Transplant. 2015 Mar;19(2):139-43.
Zafar F, Castleberry C, Khan MS, Mehta V, Bryant R 3rd, Lorts A, Wilmot I, Jefferies JL, Chin C, Morales DL. Pediatric heart transplant waiting list mortality in the era of ventricular assist devices. J Heart Lung Transplant. 2015 Jan;34(1):82-8.
Thomas TO, Chandrakasan S, O'Brien M, Jefferies JL, Ryan TD, Wilmot I, Baker ML, Madueme PC, Morales D, Lorts A. The use of a Berlin Heart EXCOR LVAD in a child receiving chemotherapy for Castleman's disease. Pediatr Transplant. 2015 Feb;19(1):E15-8.
Thomas TO, Jefferies JL, Lorts A, Anderson JB, Gao Z, Benson DW, Hor KN, Cripe LH, Urbina EM. Autonomic dysfunction: a driving force for myocardial fibrosis in young Duchenne muscular dystrophy patients? Pediatr Cardiol. 2015 Mar;36(3):561-8.
Friess MR, Marino BS, Cassedy A, Wilmot I, Jefferies JL, Lorts A. Health-related quality of life assessment in children followed in a cardiomyopathy clinic. Pediatr Cardiol. 2015 Mar;36(3):516-23.
Ryan TD, Jefferies JL, Zafar F, Lorts A, Morales DL. The evolving role of the total artificial heart in the management of end-stage congenital heart disease and adolescents. ASAIO J. 2015 Jan-Feb;61(1):8-14.
Moore RA, Madueme PC, Lorts A, Morales DL, Taylor MD. Virtual implantation evaluation of the total artificial heart and compatibility: Beyond standard fit criteria. J Heart Lung Transplant. 2014 Nov;33(11):1180-3.
Lorts A, Zafar F, Adachi I, Morales DL. Mechanical assist devices in neonates and infants. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2014;17(1):91-5.
Ryan TD, Jefferies JL, Sawnani H, Wong BL, Gardner A, Del Corral M, Lorts A, Morales DL. Implantation of the HeartMate II and HeartWare left ventricular assist devices in patients with duchenne muscular dystrophy: lessons learned from the first applications. ASAIO J. 2014 Mar-Apr;60(2):246-8.
Nicolas L. Madsen, MD, MPH 513-636-5476 firstname.lastname@example.org
Inpatient and preventative cardiology
Nicolas L. Madsen, MD, MPH, joined the Heart Institute in July 2012. He attended the University of California at Davis, where he graduated with honors. He earned his medical degree with honors at the University of Washington in 2005. Dr. Madsen completed his residency in general pediatrics and his fellowship in pediatric cardiology at Seattle Children’s Hospital in Seattle, Washington. In addition, Dr. Madsen earned a Master of Public Health from the University of Washington in 2011.
Dr. Madsen’s clinical focus is in general and preventative cardiology. His research interests also focus on the prevention of cardiac disease processes. Specifically, Dr. Madsen aims to understand the implications of traditional cardiovascular risk factors such as obesity, hypertension and sedentary lifestyle on persons with congenital heart disease. Additionally, he is focused on the prevention of sudden cardiac death in adolescent athletes by way of optimizing preparticipation sports screening. Dr. Madsen has received several national awards for his research and is an active member of the American Heart Association and American Academy of Pediatrics.
MD: University of Washington School of Medicine, Seattle, WA, 2005.
MPH: University of Washington School of Public Health, Seattle, WA, 2011.
Residency: Pediatrics, Seattle Children’s Hospital, Seattle, WA.
Fellowship: Cardiology, Seattle Children’s Hospital, Seattle, WA.
Erik C. Michelfelder, MD Co-Director, Cardiac Imaging Services, Heart Institute 513-636-1199 email@example.com
Co-Director, Cardiac Imaging Services, Heart Institute
Director, Fetal Heart Program, Heart Institute
Erik C. Michelfelder Sr., MD, is a professor of pediatrics with the University of Cincinnati College of Medicine. He is currently director of the Fetal Heart Program, and co-director of Cardiac Imaging Services for the Heart Institute at Cincinnati Children’s Hospital Medical Center.
Dr. Michelfelder graduated with a degree in biology from Bucknell University and earned his MD from the Penn State University College of Medicine. He completed his residency in pediatrics at St. Christopher’s Hospital for Children in Philadelphia, and his cardiology fellowship at C.S. Mott Children’s Hospital at the University of Michigan in Ann Arbor.
Dr. Michelfelder has been a member of the Division of Cardiology at Cincinnati Children’s Hospital Medical Center since 1998. His clinical and academic focus relate to fetal cardiology and echocardiography.
He is a member of the American Society of Echocardiography, The American Heart Association, The American College of Cardiology, The American Academy of Pediatrics, and the Society for Pediatric Research.
BS: Bucknell University, Lewisburg, PA, 1986.
MD: Penn State University College of Medicine, Hershey, PA, 1990.
Residency: St. Christopher's Hospital for Children, Temple University School of Medicine, Philadelphia, PA, 1990-1993.
Fellowship: C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, MI, 1993-1996.
Certification: Pediatrics, 1991; Pediatric Cardiology, 1998.
Ngamprasertwong P, Michelfelder EC, Arbabi S, Choi YS, Statile C, Ding L, Boat A, Eghtesady P, Holland K, Sadhasivam S. Anesthetic Techniques for Fetal Surgery: Effects of Maternal Anesthesia on Intraoperative Fetal Outcomes in Sheep Model. Anesthesiology. 2013 Apr;118(4):796-808.
Statile C, Cnota J, Gomien S, Divanovic A, Crombleholme T, Michelfelder EC. Estimated Cardiac Output and Cardiovascular Profile Score in Fetuses with High Cardiac Output Lesions. Ultrasound Obstet Gynecol. 2013 Jan;41(1):54-8.
Williams IA, Fifer C, Jaeggi E, Levine J, Michelfelder EC, Garfinkel R, Szwast AL. The Association of Fetal Cerebrovascular Resistance with Early Neurodevelopment in Single Ventricle Congenital Heart Disease. Am Heart J. 2013;165(4):544-50.
Habli M, Michelfelder EC, Cnota J, Wall D, Polzin W, Lewis D, Lim FY, Crombleholme TM. Prevalence and Progression of Recipient-twin Cardiomyopathy in Early-stage Twin-twin Transfusion Syndrome. Ultrasound Obstet Gynecol. 2012 Jan;39(1):63-8.
Divanovic A, Cnota JF, Ittenbach R, Tan X, Border WL, Crombleholme T, Michelfelder E. Characterization of Diastolic Dysfunction in Twin-Twin Transfusion Syndrome: Association between Doppler Findings and Ventricular Hypertrophy. J Am Soc Echocardiogr. 2011 Aug;24(8):834-40.
Divanovic A, Hor K, Cnota JF, Hirsch R, Kinsel-Ziter M, Michelfelder EC. Prediction and Perinatal Management of Severely Restrictive Atrial Septum in Fetuses With Critical Left Heart Obstruction: Clinical Experience Using Pulmonary Venous Doppler Analysis. J Thorac Cardiovasc Surg. 2011 Apr;141(4):988-94.
Kinsel-Ziter ML, Cnota JF, Crombleholme TM, Michelfelder EC. Twin-Reversed Arterial Perfusion Sequence: Pre- and Post- Operative Cardiovascular Findings in the Pump Twin. Ultrasound Obstet Gynecol. 2009 Nov;34(5):550-5.
Shah AD, Border WL, Crombleholme TM, Michelfelder EC. Initial Fetal Cardiovascular Profile Score Predicts Recipient Twin Outcome in Twin-Twin Transfusion Syndrome. J Am Soc Echocardiogr. 2008 Oct; 21(10):1105-8.
Michelfelder EC, Gottliebson WM, Border WL, Kinsel ML, Polzin WJ, Livingston JC, Khoury P, Crombleholme TM. Early Manifestations and Spectrum of Recipient Twin Cardiomyopathy in Twin-Twin Transfusion Syndrome: Relation to Quintero Stage. Ultrasound Obstet Gynecol. 2007 Dec;30(7):965-71.
Michelfelder EC, Gomez CA, Border W, Gottliebson W, Franklin C. Predictive Value of Fetal Pulmonary Venous Flow Patterns in Identifying the Need for Atrial Septoplasty in the Newborn With Hypoplastic Left Ventricle. Circulation. 2005 Nov 8;112(19):2974-79.
David P. Nelson, MD, PhD Director, Cardiac Intensive Care 513-803-1801 firstname.lastname@example.org
Director, Cardiac Intensive Care
Neurodevelopmental outcomes; family-centered care; cardiopulmonary interactions; physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure; cardio-renal syndrome; end of life care
David P. Nelson, MD, PhD, completed his fellowship in pediatric critical care at Harvard University, Boston Children’s Hospital. He served as the co-director of Cardiac Intensive Care at Cincinnati Children’s Hospital Medical Center from July 1996 to August 2005. In September of 2005, Dr. Nelson served as the director of Cardiac Intensive Care at Texas Children’s Hospital for four years before rejoining Cincinnati Children's as the director of Cardiac Intensive Care in 2009.
Dr. Nelson’s clinical interests include neurodevelopmental outcomes in children with acquired and congenital disease; family-centered care; cardiopulmonary interactions and the physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure in children; cardio-renal syndrome and end-of-life care.
His research focuses on quality of life and neurodevelopmental outcomes in children with acquired and congenital heart disease; etiology of adrenal dysfunction in cardiac intensive care; inflammatory organ system injury and congenital heart surgery.
PhD: University of Chicago, Chicago, IL, 1987.
MD: University of Chicago Pritzker School of Medicine, Chicago, IL, 1989.
Residency: University of Washington-Children’s Hospital Medical Center, Seattle, WA, 1989-1992.
Fellowship: Harvard University, Boston Children’s Hospital, Boston, MA, 1992-1994.
Certification: Pediatrics, 1992; Pediatric Cardiology, 1994; Pediatric Critical Care, 1998.
Moffett BS, McDade E, Rossano JW, Dickerson HA, Nelson DP. Enteral potassium supplementation in a pediatric cardiac intensive care unit: Evaluation of a practice change. Pediatr Crit Care Med. 2011 Feb 3.
Jefferies JL, Hoffman TM, Nelson DP. Heart failure treatment in the intensive care unit in children. Heart Fail Clin. 2010 Oct;6(4):531-58, ix-x. Review.
Carlo WF, Nelson DP. Inhaled nitric oxide improves oxygen saturation in children with pulmonary arteriovenous malformations after the Fontan procedure. Pediatr Crit Care Med. 2010 Aug 5.
Giuliano JS Jr, Lahni PM, Bigham MT, Manning PB, Nelson DP, Wong HR, Wheeler DS. Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass. Intensive Care Med. 2008 Oct;34(10):1851-7.
Moffet, BS, AR Mott, DP Nelson, KD Gurwitch. Medication dosing and renal insufficiency in a pediatric cardiac intensive care unit: impact of pharmacist consultation. Pediatr Cardiol. 2008 29(4):744-8.
Wheeler DS, Dent CL, Manning PB, Nelson DP. Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young. 2008 Feb;18(1):41-50.
Price JF, AR Mott, DP Nelson, AC Chang, E O'Brian Smith, JA Towbin, WJ Dreyer, SW Denfield, SL Goldstein. Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome. Pediatr Crit Care Med. 2008 9(3):279-84.
Moffett, BS, AR Mott, D.P. Nelson, SL Goldstein, JL Jefferies. Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review. Pediatr Crit Care Med. 2008 9(4):403-406.
Rossano JW, MD Taylor, EO Smith, CD Fraser, Jr., ED McKenzie, JF Price, HA Dickerson, DP Nelson, AR Mott. Glycemic profile in infants who have undergone the arterial switch operation: Hyperglycemia is not associated with adverse events. J Thorac Cardiovasc Surg. 2008 135(4):739-45.
Wheeler, DS, CL Dent, PB Manning, DP Nelson. Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young. 2008 18(1):41-50.
Wheeler, DS, JM Pearl, PB Manning, SM Schwartz, CL Dent, P Khoury, DP Nelson. Factors Prolonging Cardiac Intensive Care Unit Stay after neonatal congenital heart surgery. Pediatr Crit Care Med. 2008 18(1):41-50.
Jennifer M. Shoreman, MD 513-803-2243 email@example.com
BS: Genetics, The University of Kansas College of Liberal Arts and Sciences, Lawrence, KS, 2002.
MD: The Ohio State University College of Medicine, Columbus, OH, 2007.
Residency: Medicine / Pediatrics Residency Program, Indiana University School of Medicine, Indianapolis, IN, 2011.
Fellowship: Advanced Heart Failure and Cardiac Transplantation, Indiana University School of Medicine, Krannert Institute of Cardiology, Indianapolis, IN, 2012.
Robert M. Siegel, MD, FAAP Medical Director, Center for Better Health and Nutrition 513-636-9420 firstname.lastname@example.org
Medical Director, Center for Better Health and Nutrition
Pediatric obesity prevention and treatment
Robert M. Siegel is a professor of clinical pediatrics at the University of Cincinnati and medical director of the Center for Better Health and Nutrition of the Heart Institute. He graduated magna cum laude from Hunter College of the City University of New York and earned his MD from New York University. Dr. Siegel did his pediatric residency at Cincinnati Children’s Hospital Medical Center. He was a general pediatrician for more than twenty years before joining the Heart Institute and was president of the Medical Staff at Cincinnati Children’s from 2008 to 2010. Dr. Siegel’s research interests include dietary and physical activity interventions in obese children.
MD: New York University, School of Medicine, New York, NY, 1984.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1984-87.
Fellowship: Infectious Diseases, Cincinnati Children’s Hospital Medical Center, 1992. American Board of Pediatrics, 1988.
Certification: Pediatrics, 1988.
Kirk S, Woo J, Jone M, Siegel R. Increased Frequency of Dietitian Visits is Associated with Improved BMI Outcomes in Obese Youth Participating in a Comprehensive Pediatric Weight Management Program. Childhood Obesity. 2015;11:202-207.
Murphy A, Kist C, Gier A, Edwards NM, Gao Z, Siegel RM. The Feasibility of High Intensity Interval Exercise in Obese Adolescents. Clin Ped. 2015;54:87-90.
Inge T, Siegel R, Xanthakos S. Weight loss maintenance: A hard nut to crack. JAMA Pediatr. 2014;168:796-7.
Siegel RM, Pitnar HE, Kist C, Woo JG, Gier A, Sewell M, Lattin B, Rooney A, Kirk S. Obese Children in a Community YMCA “Fun 2B Fit” Program have a reduction in BMI Z-scores. Clin Ped. 2014;53:694-696.
Siegel RM, Kist C, Ingram L, Kirk S. An after hours rapid access pediatric weight management clinic increases show rate. Clin Ped. 2014;53:490-492.
Garbutt JM, Mandrell KM, Allen M, Sterkel R, Epstein J, Stahl K, Kreusser K, Sitrin H, Ariza A, Cohen Reis E, Siegel R, Strunk RC. Pediatric providers experience with retail-based clinics. Journal of Pediatrics. 2013;163:1384-1388.e6.
Berger KA, Lynch J, Prows CA, Siegel RM, Myers MF. Mother’s perceptions of family health history and an online parent-generated family health history tool. Clin Ped. 2012;52:70-77.
Kanetzke EE, Lynch J, Prows CA, Siegel RM, Myers MF. Perceived Utility of Parent-Generated Family Health History as a Health Promotion Tool in Pediatric Practice. Clinical Pediatrics. 2011;50:720-8.
Siegel RM, Neidhard MS, Kirk S. A Comparison of Reduced Glycemic Load and Staged Portion-Controlled Diets in Improving BMI and Other Health Outcomes of Obese Children in a Pediatric Weight Management Program. Clinical Pediatrics. 2011;50:459-461.
Siegel RM, Rich W, Khoury J. An Office-Based Low Carbohydrate Intervention in Teens: One Year Follow-up of a Six-Month Intervention. Clinical Pediatrics. 2011;50:459-461.
Michael D. Taylor, MD Director, Advanced Imaging Innovation 513-636-9806 email@example.com
Director, Advanced Imaging Innovation
Cardiac MRI; cardiac CT; and echocardiography
Michael Taylor, MD, joined the Heart Institute in July, 2010 as the director of Advanced Imaging Innovation. He was previously the director of cardiac magnetic resonance at Texas Children’s Hospital in Houston.
Dr. Taylor has expertise in cardiac magnetic resonance imaging, positron emission tomography and computed tomography. He has a dual appointment in the Cincinnati Children's Hospital Medical Center Imaging Research Center, an interdisciplinary facility of advanced imaging faculty with dedicated clinical and pre-clinical imaging equipment.
Dr. Taylor's primary interests include myocardial metabolism in heart failure, animal models of cardiac pathology, and cardiac magnetic resonance imaging of congenital and acquired heart disease.
MD: University of Wisconsin, Madison, WI, 2001.
PhD: Medical Physics, University of Wisconsin, Madison, WI, 2001.
Residency: Pediatrics, Baylor College of Medicine, Houston, TX, 2003.
Fellowship: Pediatric Cardiology, Baylor College of Medicine, Houston, TX, 2006.
Certification: Pediatrics, 2005.
Certification: Pediatric Cardiology, 2006.
Mazur W, Hor KN, Germann JT, Fleck RJ, Al-Khalidi HR, Wansapura JP, Chung ES, Taylor MD, Jefferies JL, Woodrow Benson D, Gottliebson WM. Patterns of left ventricular remodeling in patients with Duchenne Muscular Dystrophy: a cardiac MRI study of ventricular geometry, global function, and strain. Int J Cardiovasc Imaging. 2011 Jan 8.
Purevjav E, Varela J, Morgado M, Kearney DL, Li H, Taylor MD, Arimura T, Moncman CL, McKenna W, Murphy RT, Labeit S, Vatta M, Bowles NE, Kimura A, Boriek AM, Towbin JA. Nebulette mutations are associated with dilated cardiomyopathy and endocardial fibroelastosis. J Am Coll Cardiol. 2010 Oct 26;56(18):1493-502.
LP Browne, D Kearney, MD Taylor, T Chung, TC Slesnick, AC Nutting, R Krishnamurthy. ALCAPA: the role of myocardial viability studies in determining prognosis. Pediatr Radiol. 2010;40(2):163-167.
JL Jefferies, MD Taylor, J Rossano, JW Belmont, WJ Craigen. Novel cardiac findings in periventricular nodular heterotopia. Am J Med Genet. 2009; 152A(1): 165-8.
JW Rossano, MD Taylor, EO Smith, CD Fraser, ED McKenzie, JF Price, HA Dickerson, DP Nelson, AR Mott. Glycemic profile in infants who have undergone the arterial switch operation: hyperglycemia is not associated with adverse events. J Thorac Cardiovasc Surg. 2008; 135(4): 739-745.
Elaine M. Urbina, MD, MS Director, Preventive Cardiology 513-636-8265 firstname.lastname@example.org
Director, Preventive Cardiology
Elaine M. Urbina, MD, graduated from the Medical College of Georgia in 1988. She subsequently trained in pediatrics at the University of California at San Francisco. She completed her pediatric cardiology fellowship at Tulane University in New Orleans, Louisiana, in 1994 where she accepted an assistant professor position.
In addition to practicing clinical pediatric cardiology at Tulane, she was also director of preventive cardiology and the Pediatric Echocardiography Laboratory. Her research interests led her to join the world-renowned Bogalusa Heart Study, one of the longest running epidemiologic studies of CV risk factors in children. As co-investigator under the tutelage of Dr. Gerald S. Berenson, she initiated the non-invasive imaging program and supervised collection of CV data for over a decade.
Dr. Urbina joined Cincinnati Children's Hospital Medical Center as associate professor within the UC Department of Pediatrics in October of 2003 and became director of preventive cardiology in 2006. This new opportunity allowed her to concentrate her clinical practice on the diagnosis and treatment of high blood pressure and cholesterol. She continues her research studies concentrating on non-invasive imaging methods to measure atherosclerosis with a focus on vascular function abnormalities using the modalities of:
Her current research includes the application of these new techniques to study the roles that pre- and post-natal nutrition, overweight, high blood pressure, cholesterol and diabetes play in the development of hardening of the arteries.
MD: Medical College of Georgia, Augusta, GA, 1988.
Residency: University of California, San Francisco, CA, 1990; Tulane University, New Orleans, LA 1991 (Pediatrics).
Fellowship: Tulane University, New Orleans, LA, 1994 (Pediatric Cardiology).
Certification: Pediatrics 1991; Pediatric Cardiology 1994.
Urbina EM, Khoury PR, McCoy C, Daniels SR, Kimball TR, Dolan LM. Cardiac and vascular consequences of pre-hypertension in youth. J Clin Hypertens (Greenwich). May 2011;13(5):332-342.
Urbina EM, Dolan LM, McCoy CE, Khoury PR, Daniels SR, Kimball TR. Relationship between elevated arterial stiffness and increased left ventricle mass in adolescents and young adults. J Pediatr. May 2011;158(5):715-721.
Urbina EM, Kimball TR, Khoury PR, Daniels SR, Dolan LM. Increased arterial stiffness is found in adolescents with obesity or obesity-related type 2 diabetes mellitus. J Hypertens. Aug 2010;28(8):1692-1698.
Urbina EM, Wadwa RP, Davis C, Snively BM, Dolan LM, Daniels SR, Hamman RF, Dabelea D. Prevalence of increased arterial stiffness in children with type 1 diabetes mellitus differs by measurement site and sex. J Pediatr. May 2010;156(5):731-737.
Urbina EM, Kimball TR, McCoy CE, Khoury PR, Daniels SR, Dolan LM. Youth with obesity and obesity-related type 2 diabetes mellitus demonstrate abnormalities in carotid structure and function. Circulation. Jun 2009;119(22):2913-2919.
Urbina EM, Bean JA, Daniels SR, D’Alessio D, Dolan LM. Overweight and hyperinsulinemia provide individual contributions to comprises in brachial artery distensibility in healthy adolescents and young adults: brachial distensibility in children. J Am Soc Hypertens. Jun 2007;1(3):200-207.
Urbina EM, Kieltkya L, Tsai J, Srinivasan SR, Berenson GS. Impact of multiple cardiovascular risk factors on brachial artery distensibility in young adults: The Bogalusa Heart Study. Am J Hypertens. Jun 2005;18:767-771.
Urbina EM, Srinivasan SR, Kieltyka RL, Tang R, Bond MG, Chen W, Berenson GS. Correlates of carotid artery stiffness in young adults: The Bogalusa Heart Study. Atherosclerosis. Sep 2004;176(1):157-164.
Urbina EM, Srinivasan SR, Tang R, Bond MG, Kieltyka L, Berenson GS. Impact of multiple coronary risk factors on the intima-media thickness of different segments of carotid artery in healthy young adults: The Bogalusa Heart Study. Am J Cardiol. Nov 2002;90(9):953-958.
Urbina EM, Gidding SS, Bao W, Pickoff AS, Berdusis K, Berenson GS. Effect of body size, ponderosity and blood pressure of the left ventricular growth in children and young adults in Bogalusa Heart Study. Circulation. May 1995;91(9):2400-2406.
Accelerated CV Aging in Youth Related to CV Risk Factor Clusters. Principal Investigator. National Heart, Lung and Blood Institute. Jan 2011-Dec 2016.
SEARCH 3: Cohort Study - Ohio site. Co-Investigator. Centers for Disease Control & National Institutes of Health. Sept 2010-Oct 2015.
Gruschen R. Veldtman, FRCP, MBChB Director of Inpatient ACHD Services, Heart Institute 513-803-2243 email@example.com
Director of Inpatient ACHD Services, Heart Institute
Spectrum of adult congenital heart disease: the Fontan circulation; interventional cardiology; pregnancy cardiology; pulmonary hypertension in congenital heart disease
Gruschen R. Veldtman, FRCP, MBChB, is appointed in the Heart Institute at Cincinnati Children's Hospital Medical Center. His major achievement has been the establishment of patient and science centered clinical programs that serve adult patients with various complexity of congenital heart conditions. His major academic contributions have been in the field of liver disease as it relates to the Fontan circulation.
General Paediatrics and Neonates, Royal Hospital for Sick Children, Glasgow, 1995.
Paediatric Cardiology, Leeds General Infirmary, 1999.
Fellowship: Adult Congenital Heart Disease, Toronto 2000.
Research Fellowship: Hospital For Sick Children Toronto, 2001.
Fellowship: Adult Congenital Heart Disease, Mayo Clinic, 2002.
Fellowship: Paediatric Interventional Cardiology, 2003.
Robert H. Beekman III, MD 513-636-7072 firstname.lastname@example.org
Cardiac catheterization; intervention for congenital heart disease; quality improvement
Robert H. Beekman, III, MD, is currently professor of pediatric cardiology at Children's Hospital Medical Center of Cincinnati within the University of Cincinnati College of Medicine. Dr. Beekman's subspecialty interests involve cardiovascular physiology, interventional pediatric cardiology and clinical quality improvement.
A native of California, Dr. Beekman graduated from Occidental College in Los Angeles, and earned his MD from Duke University in Durham, NC. Dr. Beekman completed his pediatric internship and residency at UCLA Medical Center, and his pediatric cardiology fellowship at the University of Michigan Medical Center, Ann Arbor, Mich. Dr. Beekman also obtained a master's degree in statistical analysis and research design from the University of Michigan. From 1985-1996, Dr. Beekman was a member of the Division of Pediatric Cardiology at the University of Michigan School of Medicine. From 1996-2009 he was director of Cardiology at Children's Hospital Medical Center of Cincinnati, and professor of pediatrics at the University of Cincinnati School of Medicine.
Dr. Beekman is passionate about improving care for patients born with congenital heart disease, and throughout his career has been an active clinician and educator. Dr. Beekman's academic interests relate to cardiovascular physiology, cardiac catheterization and quality improvement. He has published more than 200 manuscripts in cardiology and pediatric journals. Dr. Beekman is the chair of the JCCHD National Pediatric Cardiology Quality Improvement Collaborative and chair of the ACC Adult Congenital and Pediatric Cardiology Section. He has been chair of the Section on Cardiology and Cardiac Surgery of the American Academy of Pediatrics and president of the Society of Pediatric Cardiology Training Program Directors.
MD: Duke University School of Medicine, Durham, NC, 1976.
MS: Clinical Research Design and Statistics, University of Michigan, Ann Arbor, MI, 1986.Residency: Pediatrics, UCLA Medical Center, Los Angeles, CA, 1976 to 1979.Fellowship: Pediatric Cardiology, CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 1979 to 1982.Certification: Pediatrics, 1981; Pediatric Cardiology, 1983.
Seckeler MD, Hirsch R, Beekman RH, Goldstein BH. A new predictive equation for oxygen consumption in children and adults with congenital and acquired heart disease. Heart. 2015;101(7):517-524.
Brown DW, Cohen KE, O’Brien P, Gauvreau K, Klitzner TS, Beekman RH, Kugler JD, Martin GR, Neish SR, Rosenthal GL, Lannon C, Jenkins KJ. Impact of prenatal diagnosis in survivors of initial palliation of single ventricle heart disease: Analysis of the National Pediatric Cardiology Quality Improvement Collaborative database. Pediatr Cardiol. 2015;36(2):314-321.
Anderson JB, Beekman RH, Kugler JD, Rosenthal GL, Jenkins KJ, Klitzner TS, Martin GR, Neish SR, Darbie L, King E, Lannon C. Use of a learning network to improve variation in interstage weight gain after the Norwood operation. Congenital Heart Disease. 2014;9(6):512-520.
Moore J, Vincent R, Beekman R, Benson L, Bergersen L, Holzer R, Jayaram N, Jenkins K, Li Y, Ringel R, Rome J, Martin G. Procedural results and safety of common interventional procedures in congenital heart disease: Initial report from the National Cardiovascular Data Registry. J Am Coll Cardiol. 2014;64:2439-2451.
Zussman M, Hirsch R, Beekman RH, Goldstein BH. Impact of percutaneous interventions for pulmonary artery stenosis in Alagille syndrome. Congenital Heart Disease. 2014.
Villafane J, Lantin-Hermoso MR, Bhatt AB, Tweddell JS, Geva T, Nathan M, Elliott MJ, Vetter VL, Paridon SM, Kochilas L, Jenkins KJ, Beekman RH, Wernovsky G, Towbin JA. D-Transposition of the great arteries: The current era of the arterial switch operation. J Am Coll Cardiol. 2014;64:498-511.
Armsby L, Beekman RH, Benson L, Fagan T, Hagler D, Hijazi ZM, Holzer R, Ing F, Kreutzer J, Lang P, Levi D, Latson L, Moore P, Mullins C, Ruiz C, Vincent R.SCAI expert consensus statement for advanced training programs in pediatric and congenital interventional cardiac catheterization. Cath and Cardiovasc Intervent. 2014.
Villafane J, Baker GH, Austin E, Miller S, Peng L, Beekman R. Melody pulmonary valve bacterial endocarditis: Experience in four pediatric patients and a review of the literature. Cath and Cardiovasc Intervent. 2014;84:212-218.
Lin CH, Hegde S, Marshall AC, Porras D, Gauvreau K, Beekman RH, Torres A, Vincent JA, Moore JW, Holzer R, Armsby L, Bergersen L. Incidence and management of life threatening adverse events during cardiac catheterization for congenital heart disease. Pediatric Cardiology. 2014;35:140-148.
Baker-Smith CM, Wilhelm CM, Neish SR, Klitzner TS, Beekman RH, Kugler JD, Martin GR, Lannon C, Jenkins KJ, Rosenthal GL. Predictors of prolonged length of intensive care unit stay after Stage I palliation: A report from the National Pediatric Cardiology Quality Improvement Collaborative. Pediatric Cardiol. 2014;25(3):431-440.
Nicole M. Brown, MD 513-636-4432 email@example.com
MD: University of Cincinnati, Cincinnati, OH.
Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Fellowship: Pediatric Cardiology, Children's Hospital of Pittsburgh, Pittsburgh, PA.
Jonathan W. Byrnes, MD Attending Cardiac Intensivist, Cardiac Intensive Care Unit 513-803-1801 firstname.lastname@example.org
Attending Cardiac Intensivist, Cardiac Intensive Care Unit
Jonathan Byrnes, MD, is an assistant professor of pediatrics with the University of Cincinnati College of Medicine and an attending cardiac intensivist in Cincinnati Children’s Hospital Medical Center’s Cardiac Intensive Care Unit. He joined the faculty in July 2013.
A native of Mississippi, Dr. Byrnes graduated with honors from University of Mississippi