Clinical Trials Office

Does Your Child Have ADD or ADHD? 8 to 12 Year Olds Needed for a Research Study

What is the purpose of this study?

The purpose of this research study is to understand brain development in children with Attention Deficit Disorder (ADD) and Attention Deficit Hyperactivity Disorder (ADHD) compared to typical children who do not have ADD, ADHD or other behavioral conditions.  The focus is on learning more about the brain’s abilities to control coordinated hand and finger movements.

Who can participate?

Those eligible to participate are children 8 to 12 years old who:

  • Have been diagnosed with ADD or ADHD
  • Are right-handed

AND

  • Have no significant neurological, developmental or psychiatric diagnoses.

What is involved?

The study involves 2 visits.  The following is a list of procedures that may take place during the study:

  • An initial screening
  • Parent questionnaires
  • MRI brain scan
  • Clinical assessment/neuropsychological testing (achievement testing)
  • Several tests of coordination
  • A procedure called a Transcranial Magnetic Stimulation (TMS) which looks at brain development and motor skills
  • Computer games
  • A dose of a carbidopa/levodopa (sinemet®) pill or placebo (a pill that looks like the study drug but contains no medication)

A detailed list of procedures will be provided to anyone interested in knowing more about this study.  

What are the benefits?

Your child may receive no direct benefit from participating in this study. The greatest benefit is that your child may be contributing to research that helps other children.  Research studies are essential in finding new and improved treatments and diagnostic tools.

Will I get all the facts about the study?

Parents interested in having their child participate will be given a consent form that thoroughly explains all of the details of the study.  The form covers all of the procedures, the risks, the benefits, the pay, who to contact with questions or concerns and more.  A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.  Study procedures will not begin until a parent or guardian has signed this form and, if of age, the child has given at minimum his/her verbal agreement.

Do participants receive pay, compensation or reimbursement?

Families will receive up to $50 per day (for 2 days) for their participation.

Who should I contact for more information?

David Huddleston

david.huddleston@cchmc.org

513-636-3201

Cincinnati Children’s Hospital Medical Center

Division of Neurology

3333 Burnet Avenue

Cincinnati, OH  45229-3039

Principal Investigator

Donald Gilbert, MD, MS

Director, Tourette Syndrome and Movement Disorders Clinics

Cincinnati Children’s Hospital Medical Center

Division of Neurology