Study to Test Safety of a Virus Therapy Children / Young Adults- Conditions:
Adult Studies,
Cancer - Hemangioma and Vascular Malformation,
Cancer - Kidney Tumors,
Cancer - Leukemia and Lymphoma,
Cancer - Liver Tumors,
Cancer - Musculoskeletal Tumors,
Cancer - Neurofibromatosis Tumors,
Medications,
Vaccines
- Gender:
Female,
Male
Cincinnati Children’s Hospital Medical Center is conducting a research study, sometimes known as a clinical trial or clinical study, to test how safe and well tolerated the study drug is in children and young adults with certain cancers. Researchers want to see what effects - good or bad - the stu...
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131-I-MIBG Expanded Access: An Open Label, Expanded Access Protocol Using I-Metaiodobenzylguanidine (131I-MIBG) Therapy in Patients With Refractory Neuroblastoma- Conditions:
Adult Studies,
Cancer - Neuroblastoma,
Medications
- Gender:
Female,
Male
Provide palliative therapy with MIBG for patients with advanced neuroblastoma Gain more information about acute and late toxicity of 131I-MIBG therapy for patients with refractory neuroblastoma ...
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NANT 2007-02: Bevacizumab, Cyclophosphamide, and Zoledronic Acid in Treating Patients with Recurrent or Refractory High-Risk Neuroblastoma- Conditions:
Adult Studies,
Cancer - Neuroblastoma,
Medications
- Gender:
Female,
Male
This phase I trial is studying the side effects of giving bevacizumab together with cyclophosphamide and zoledronic acid in treating patients with recurrent or refractory high-risk neuroblastoma....
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NANT 2007-03: Vorinostat With 131I-MIBG Therapy for Resistant/Relapsed Neuroblastoma: A Phase I Study- Conditions:
Adult Studies,
Cancer - Neuroblastoma,
Medications
- Gender:
Female,
Male
This phase I trial is studying the side effects and best dose of giving vorinostat together with iobenguane I 131 in treating patients with resistant or relapsed neuroblastoma....
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A Research Study for Children (12 and older) and Adults with Sickle Cell Disease- Zileuton- Conditions:
Adult Studies,
Asthma,
Hematology - Sickle Cell and Hemoglobin,
Medications
- Gender:
Female,
Male
We find that patients with sickle cell disease (SCD) have inflammation in their blood even when they are well, and their lung function tests suggest a tendency to have asthma. Inflammation and asthma increase the number of acute sickle events. Our laboratory research shows that both inflammation an...
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Help Us Build a Blood and Tissue Bank- Conditions:
Adult Studies,
Hematology - Fanconi Anemia,
Hematology - Hemophilia,
Hematology - Thrombosis,
Hematology - Sickle Cell and Hemoglobin
- Gender:
Female,
Male
Researchers studying hematology are collecting samples and clinical information to learn more about non-malignant (not cancerous) blood disorders to find better treatments for these disease and possibly other diseases as well. Non-malignant blood disorders include anemia, bleeding and thrombotic di...
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Computed Tomography (CT) Induced Double-Stranded DNA Breaks Formation and Subsequent Repair as a Marker of Radiation Sensitivity- Conditions:
Adult Studies,
Human Genetics,
Other
- Gender:
Female,
Male
People with certain genetic or inherited conditions are more sensitive to radiation than unaffected people. We want to see if we can use a special blood test, drawn after a CT scan, which is a specialized type of X-ray that uses a very small dose of radiation, to figure out which people are special...
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Early Detection of Acute Renal Injury in Blood and Marrow Transplant Patients Using Urinary Proteomics- Conditions:
Adult Studies,
Cancer - Bone Marrow Transplantation,
Cancer - Immune Deficiency and Histiocytosis
- Gender:
Female,
Male
The purpose of this research study is to find out if urine obtained from patients who are undergoing a blood or marrow transplant, contains proteins that can help predict if the kidneys have been injured. Kidneys can be injured from the chemotherapy, from infections, and/or from other medications u...
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Repository of Tissue Samples and Data from Patients with Fanconi Anemia- Conditions:
Adult Studies,
Cancer - Immune Deficiency and Histiocytosis,
Hematology - Fanconi Anemia
- Gender:
Female,
Male
The purpose of this research study is to help investigators learn more about Fanconi anemia. ...
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The Severe Chronic Neutropenia International Registry- Conditions:
Adult Studies,
Cancer - Immune Deficiency and Histiocytosis
- Gender:
Female,
Male
The purpose of this research study is to learn more about the cause and outcome for Severe Chronic Neutropenia (SCN). The objective of the Registry is to collect information on the natural course of SCN and its response to treatment with the blood stimulating factor called granulocyte colony stimul...
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