Clinical Trials

A Research Study for Healthy Children and Teens

What is the purpose of this study?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to establish what areas of the brain are normally used while listening, speaking or paying attention.

Who can participate?

Children and teens 0 to 18 years old with no history of mental illness or head trauma and no history of mental illness in their immediate family may be eligible to participate.  Also, participants should have at least average grades (C- or above) in school.  Because an MRI scan is involved in this study, children and teens should not have orthodontic braces.


  • From 0 To 18  years old


  • Adult Studies
  • Healthy Infants, Children and Adolescent Studies

What is involved?

You - as the participant (if 18) - or your child will be in the research study for approximately one year and come in for at least two visits.  Here are some of the procedures:

You or your child will:

  • Answer screening questions over the phone
  • Have the opportunity to come in to our Imaging Research Center to meet with the study staff
  • Be examined by a neurologist (a doctor who specializes in the nervous system) to check reflexes, balance, vision, etc.
  • Have a hearing test
  • Have an MRI (magnetic resonance imaging) scan
  • Take tests that look at intelligence, language and other skills

What are the benefits?

You or your child will not receive a direct medical benefit.  However, the information learned from this research study may help us to have a better understanding of language and attention development and language and attention disorders in the future.  Also, your participation may help by affecting the treatment of neurological diseases such as epilepsy or brain tumors.

Will I get all the facts about the study?

You - as the participant - or as a parent interested in having their child participate will be given a consent form that thoroughly explains all of the details of the study.  The form covers all of the procedures, the risks, the benefits, the pay, who to contact with questions or concerns and more.  A member of the study staff will review the consent form with you and will be sure that all of your questions are answered. 

What are the risks and discomforts of the study?

As the study includes MRI scans, you or your child could become anxious while in the scanner or feel claustrophobic, but you or he/she can watch a movie with special goggles or listen to music with headphones during the scan (goggles and headphones are provided).  There are no known biological risks associated with the MRI scans.

Do participants receive pay, compensation or reimbursement?

Families will receive $50 per visit up to 3 visits for time and travel. 

Who should I contact for more information?

Julie Franks-Henry
Pediatric Neuroimaging Research Consortium
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave., MLC 5033
Cincinnati, OH  45229-3039

Where can I find additional information?

Principal Investigator

Scott Holland, PhD
Professor of Radiology, Pediatrics, Neuroscience, Physics & Biomedical Engineering
Imaging Research Center
Cincinnati Children’s Hospital Medical Center