Juvenile Idiopathic Arthritis (JIA) / Family Blood Samples

What is the purpose of this study?

The purpose of this study is to locate the areas of human chromosomes (genes) that are linked to JIA.

Juvenile Idiopathic Arthritis (JIA) is a complex genetic trait, meaning a person needs to have a combination of different genes to develop the disease.

Who can participate?

  • Approximately 5000 participants and their family members will take part in this study and approximately 3000 more across the United States or worldwide.
  • Participants include the child with the diagnosis of JIA, and willing family members (parents and siblings only)
  • Participation is a one-time blood sample (a needle stick, usually in the arm)
  • Clinical information (from the child's medical record) will be collected as study data; demographic information (name, address, phone numbers) will be collected from patients and family members


  • Autoimmune
  • Human Genetics
  • Rheumatology

What is involved?

  • For the child with JIA, collection of study blood sample can happen as part of a regularly scheduled appointment, at the same time the rheumatologist requires blood tests
  • We will assist any interested family members' participation in the study by one of the following two options:
  • Schedule coming to Cincinnati Children's Hospital Medical Center at a convenient time for them
  • (For those living out-of-town) make arrangements with a lab / doctor's office close to where they live, and then have blood samples sent to Cincinnati Children's

Who should I contact for more information?

For more information about the Juvenile Idiopathic Arthritis (JIA) / Family Blood Samples study, please contact:

  • Study Coordinator, Sandy Kramer, 513-636-7692