Clinical Trials

Research Study to Learn More about What Causes Lupus

What is the purpose of this study?

This is a research study to determine the cause of lupus and to improve understanding of the disease. The study specifically seeks to help find the genes that are involved in lupus development and to learn how they work differently in people with and without the condition. Studying lupus at the genetic level to determine its causes may lead to advances that will improve how it is diagnosed and treated.

Who can participate?

Several groups of people can participate in this study: 

    • Children and adults with lupus 
    • First-degree (parent, sibling, child) and second-degree (grandparent, aunt/uncle, niece/nephew) relatives of lupus patients 
    • Healthy Hoxworth Center blood donors 
    • Healthy adults

Family members, healthy adults and blood donor participants cannot have a personal history of lupus.

Conditions

  • Autoimmune
  • Human Genetics
  • Lupus

What is involved?

Participants will be involved in the study only for as long as they provide samples. Participants will be asked to provide a blood sample at the time of their next medically necessary blood draw, blood donation, or in a local clinic or hospital of their choice. Typically, blood will be drawn only one time; however, there is a possibility that participants may be asked to submit a second sample of blood at a later date. Specimens collected during this study will be de-identified and stored indefinitely at Cincinnati Children’s Hospital Medical Center for future lupus research.

What are the benefits?

There may be no direct medical benefit from participating in this study. The information learned from this study may benefit others in the future.

Will I get all the facts about the study?

Participants interested in taking part in the study will be given a consent form that thoroughly explains all of the details of the study. The form covers all of the procedures, the potential risks and benefits, the pay, who to contact with questions or concerns and more. A member of the study staff will review the consent form with participants to ensure all questions are answered. Study procedures will not begin until participants have signed this consent form.

Who should I contact for more information?

Carrie Weaver
Clinical Research Coordinator III
(513) 803-3307
Center for Autoimmune Genomics and Etiology
Cincinnati Children’s Hospital Medical Center
3333 Burnet Avenue
Cincinnati, OH 45229-3039
carrie.weaver@cchmc.org

Principal Investigator

John Harley, MD, PhD
Principal Investigator, Director
Division of Rheumatology
Center for Autoimmune Genomics and Etiology
Cincinnati Children’s Hospital Medical Center