Lupus Puberty Study

What is the purpose of this study?

The purpose of this study is to learn more about why systemic lupus erythematosus (SLE) is more common in females than males, and why it often seems to get worse during puberty.

Who can participate?

  • Approximately 50 participants (females and males eight- to twleve-years-old) from centers throughout US and Canada; three to five from Cincinnati Children's Hospital Medical Center
  • Approximately 13 study visits over three year study period
  • Visits will always be combined with clinic visits to your doctor; participation may increase the length of your typical  visit by 15 to 20 minutes


  • From 8 To 12  years old

What is involved?

  • Physician to fill out special study forms
  • Physician exam for stage of puberty 
  • Blood and urine samples
  • Questionnaire about general health (three visits only)
  • (Optional) 1x blood and urine sample for Genetic portion of study; see informed consent form for details

Do participants receive pay, compensation or reimbursement?

The child will receive $10 for each completed study visit.

Who should I contact for more information?

Study Coordinator – Jamie Eaton

Principal Investigator

Principal  Investigator - Hermine Brunner, MD