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Clinical Trials Office

  • Showing 1 - 4 of 7 records
    Intravenous Mepolizumab for Eosinophilic Esophagitis
    • Conditions:  Eosinophilic Disorders, Gastroenterology, Hepatology and Nutrition, Medications
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a randomized, double-blind, parallel group clinical trial of intravenous mepolizumab. This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of... More
    Anti-IL-5 Open-Label Study for Hypereosinophilic Syndrome
    • Conditions:  Eosinophilic Disorders, Medications
    • Gender:  Female, Male
    GSK will sponsor this compassionate use trial of mepolizumab to treat subjects with HES who have significant clinical disease due to HES, are unresponsive to medication used to treat HES and those who have demonstrated clinical benefit with previous anti IL-5 treatment. The overall objective of thi... More
    Intravenous QAX576 Treatment for Eosinophilic Esophagitis
    • Conditions:  Adult Studies, Eosinophilic Disorders, Medications
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a double-blinded, randomized, placebo-controlled clinical trial of intravenous QAX576, a monoclonal antibody to interleukin-13 (IL-13), in the treatment of Eosinophilic Esophagi... More
    Eosinophils and Inflammation, an Expanded Study
    • Conditions:  Adult Studies, Ear Nose and Throat (ENT), Eosinophilic Disorders
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting an expanded study on eosinophils and inflammation. The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration and function and to... More

 
  • Contact Us

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    The Clinical Trials Office at Cincinnati Children’s provides sponsors and investigators with comprehensive support services, research tools, personnel and facilities to conduct or facilitate pediatric and adult clinical research studies. Contact us for more information.