Clinical Trials Office

  • Showing 1 - 6 of 6 records
    Intravenous Mepolizumab for Eosinophilic Esophagitis
    • Conditions:  Eosinophilic Disorders, Gastroenterology, Hepatology and Nutrition, Medications
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a randomized, double-blind, parallel group clinical trial of intravenous mepolizumab. This study will evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of... More
    Anti-IL-5 Open-Label Study for Hypereosinophilic Syndrome
    • Conditions:  Eosinophilic Disorders, Medications
    • Gender:  Female, Male
    GSK will sponsor this compassionate use trial of mepolizumab to treat subjects with HES who have significant clinical disease due to HES, are unresponsive to medication used to treat HES and those who have demonstrated clinical benefit with previous anti IL-5 treatment. The overall objective of thi... More
    Eosinophils and Inflammation, an Expanded Study
    • Conditions:  Adult Studies, Ear Nose and Throat (ENT), Eosinophilic Disorders
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting an expanded study on eosinophils and inflammation. The purpose of this study is to elucidate the mechanisms underlying eosinophil growth, survival, migration and function and to... More
    Evaluation of Eosinophil-Associated Gastrointestinal Disorders
    • Conditions:  Eosinophilic Disorders, Gastroenterology, Hepatology and Nutrition
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a clinical and immunological evaluation of eosinophil-associated gastrointestinal disorders. The purpose of this study is to conduct a translational study in patients with prima... More
    Fluticasone Propionate (FP) Treatment
    • Conditions:  Eosinophilic Disorders, Medications
    • Gender:  Female, Male
    The Cincinnati Center for Eosinophilic Disorders at Cincinnati Children's Hospital Medical Center is currently conducting a double blinded, randomized trial of swallowed 1760mcg Fluticasone propionate (FP) versus placebo in the treatment of Eosinophilic Esophagitis. The purpose of this study is to ... More
    Other Current Clinical Studies
    • Conditions:  Adult Studies, Eosinophilic Disorders, Medications, Urology, Other
    • Gender:  Female, Male
    Members of the Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children's Hospital Medical Center have a large number of active clinical studies which are listed on this page. William F. Balistreri, MDPegylated Interferon +/— Ribavirin for Children with HCVCCHMC IRB# 04-2-31Typ... More

 
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    The Clinical Trials Office at Cincinnati Children’s provides sponsors and investigators with comprehensive support services, research tools, personnel and facilities to conduct or facilitate pediatric and adult clinical research studies. Contact us for more information.