Clinical Trials Office

Research Study for Healthy Adults 55 to 74 Years Old

What is the purpose of this study?

Cincinnati Children’s is conducting a research study, sometimes known as a clinical trial or clinical study, to evaluate whether giving 2 injections of the pneumonia vaccine Prevnar 13 ® to adults who have been previously vaccinated with the more common pneumonia vaccine Pneumovax® improves their protection.

Who can participate?

Healthy adults 55 to 74 years old who

  • Have previously received the pneumonia vaccine 3 to 7 years ago


  • Have never received the pneumonia vaccine

What is involved?

The study involves 3 study visits during a 6 month period.  A detailed list of procedures will be provided to those interested in knowing more about this study.  Here are some of the procedures:


  • Will be asked about your medical history
  • Will have your blood pressure, heart rate and temperature taken and may have a brief physical exam
  • Will submit blood samples
  • Will receive the study vaccine
  • Be given a memory aid and thermometer to record any symptoms and your temperature
  • Be called to collect the memory aid information

What are the benefits?

You may not receive a direct medical benefit from participating in this study. However, the results from this study may help researchers to develop ways to better protect people against pneumococcal infection in the future.

Will I get all the facts about the study?

You will be given a consent form that thoroughly explains all of the details of the study.  The form covers all of the procedures, the risks, the benefits, the pay, whom to contact with questions or concerns and more.  A member of the study staff will review the consent form with you and will be sure that all of your questions are answered.  

Do participants receive pay, compensation or reimbursement?

Participants may receive up to $250 for time and travel.

Who should I contact for more information?

Gamble Program for Clinical Studies

Cincinnati Children’s Hospital Medical Center


Principal Investigator

Rebecca Brady, MD

Division of Infectious Diseases

Cincinnati Children’s Hospital Medical Center