Hydrocephalus Study for Children Up to 3 Years Old

What is the purpose of this study?

Cincinnati Children’s is conducting a research project to study the white matter of the brain in children with hydrocephalus (white matter connects areas in the brain responsible for normal function). Assessments will be done through MRIs and neuropsychological tests of behavior and development.

Who can participate?

Children from birth to 3 years old diagnosed with hydrocephalus and who have been referred for an MRI and shunt surgery may be eligible to participate.


  • From 0 To 3  years old


  • Hydrocephalus
  • Neurology

What is involved?

The study lasts for approximately 1 year and involves 3 visits for neurological tests. The following is a list of procedures that will take place during the study:

Your child will:

  • Have clinical MRI scans as scheduled (we will ask for your permission to use the clinical MRI data for research purpose)
  • Take IQ intelligence tests and other behavioral and neuropsychological tests (3 visits) looking at how the brain functions

You, as the parent, will be asked to complete questionnaires about your child’s behavior and disposition.

What are the benefits?

The neuropsychological (looking at how the brain functions) testing administered by a certified neuropsychologist and a brief IQ report will be provided free of charge in this research project. Your child may receive no other direct benefit from participating in this study. The greatest benefit is that your child may be contributing to research that helps other children with hydrocephalus in the future.

Will I get all the facts about the study?

Parents/Guardians will be given a consent form that thoroughly explains all of the details including the procedures, the risks, the benefits, the pay, contact persons and more. A member of the study staff will review the consent form with you and will make sure that all of your questions are answered. Study procedures will not begin until a parent or guardian has signed this form.

What are the risks and discomforts of the study?

There is a possibility that a child may become tired or bored while taking the neuropsychological tests involved in this study. Breaks will be given as requested during these tests to prevent these problems.

Do participants receive pay, compensation or reimbursement?

Families will receive up to $75 at each visit (for time and travel associated with neuropsych testing) up to $225.  

Who should I contact for more information?

Weihong Yuan, Study Principal Investigator
Neuroimaging Research Consortium
Cincinnati Children’s Hospital Medical Center
3333 Burnet Ave., Cincinnati, OH 45229