Clinical Trials Office

  • Showing 1 - 8 of 8 records
    Early Detection of Acute Renal Injury in Blood and Marrow Transplant Patients Using Urinary Proteomics
    • Conditions:Adult Studies, Cancer - Bone Marrow Transplantation, Cancer - Immune Deficiency and Histiocytosis
    • Gender:Female, Male
    The purpose of this research study is to find out if urine obtained from patients who are undergoing a blood or marrow transplant, contains proteins that can help predict if the kidneys have been injured. Kidneys can be injured from the chemotherapy, from infections, and/or from other medications u... More
    Hybrid ImmunoTherapy (ATG/Dexamethasone/Etoposide) for HLH: The HIT-HLH trial
    • Conditions:Cancer - Immune Deficiency and Histiocytosis
    • Gender:Female, Male
    Cincinnati Children’s is conducting a research study to evaluate the safety and effectiveness of a treatment regimen combining two previous approaches to treat patients with HLH.... More
    Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death
    • Conditions:Cancer - Immune Deficiency and Histiocytosis, Human Genetics
    • Gender:Female, Male
    The purpose of this protocol is to find the biochemical and genetic causes of inherited immune diseases affecting lymphocytes. A second purpose is to develop new knowledge which will help research doctors find better ways to prevent, diagnosis, and treat these inherited immune diseases. ... More
    Repository of Tissue Samples and Data from Patients with Fanconi Anemia
    • Conditions:Adult Studies, Cancer - Immune Deficiency and Histiocytosis, Hematology - Fanconi Anemia
    • Gender:Female, Male
    The purpose of this research study is to help investigators learn more about Fanconi anemia. ... More
    SBDS Protein Expression in Peripheral Blood Leukocytes
    • Conditions:Cancer - Immune Deficiency and Histiocytosis, Human Genetics
    • Gender:Female, Male
    Shwachman-Diamond syndrome (SDS) is a rare condition which is usually diagnosed in infancy or early childhood. It can affect a wide range of organs but most commonly the digestion and the blood system are involved. Bone abnormalities and poor growth are also often seen in SDS patients. Researchers ... More
    The Severe Chronic Neutropenia International Registry
    • Conditions:Adult Studies, Cancer - Immune Deficiency and Histiocytosis
    • Gender:Female, Male
    The purpose of this research study is to learn more about the cause and outcome for Severe Chronic Neutropenia (SCN). The objective of the Registry is to collect information on the natural course of SCN and its response to treatment with the blood stimulating factor called granulocyte colony stimul... More
    Investigation into the Immunologic and Molecular Basis of Primary Immune Deficiencies and Immune Regulatory Disorders
    • Conditions:Autoimmune, Cancer - Immune Deficiency and Histiocytosis, Hematology - Fanconi Anemia, Hematology - Hemophilia, Hematology - Thrombosis, Hematology - Sickle Cell and Hemoglobin, Rheumatology
    • Gender:Female, Male
    The purpose of this research study is to help the doctors learn more about disorders of the immune system. The research doctors of the Cancer and Blood Diseases Institute at Cincinnati Children's Hospital Medical Center would like to collect blood / tissue samples from patients with a diagnosis or ... More
    NI-0501: A Study to Investigate the Safety and Efficacy of an Anti-IFNγ mAb in Children Affected by Primary Hemophagocytic Lymphohistiocytosis
    • Conditions:Cancer - Immune Deficiency and Histiocytosis
    • Gender:Female, Male
    Cincinnati Children’s is participating in a research study sponsored by NovImmune S.A. to evaluate the safety, tolerability and preliminary efficacy of a new drug (NI-0501) aimed at controlling disease activity in patients diagnosed with primary hemophagocytic lymphohistiocytosis who show an un... More

 
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    The Clinical Trials Office at Cincinnati Children’s provides sponsors and investigators with comprehensive support services, research tools, personnel and facilities to conduct or facilitate pediatric and adult clinical research studies. Contact us for more information.