Is Your Teenage Daughter Depressed? 14 to 19 Year Old Girls Needed for a Research Study

What is the purpose of this study?

We want to improve our understanding of adolescents affected by depression.

Participants will not receive any kind of treatment for depression in this research study, but we will investigate how depression affects the brain.

Who can participate?

Those eligible for participation are teenage girls, between the ages of 14 and 19 years old, who:

  • Are currently affected by depression (a diagnosis is not needed)
  • Have not yet been treated with medication for depression


  • Have no significant neurological disorders (like seizures) or developmental diagnoses.

What is involved?

If you or your child qualify for this study and you agree to participate, you will have one study visit that will last 3 to 4 hours long.

The following is a list of procedures that may take place during the study visit:

  • Preliminary screening
  • Parent questionnaires
  • Clinical assessments/neuropsychological testing - playing on a computer which tests different brain functions, including memory, reading, and paying attention
  • Transcranial Magnetic Stimulation (TMS) – a test that uses a special kind of magnet to measure brain development and motor skills

A detailed list of procedures will be provided to anyone interested in learning more about this study.

What are the benefits?

You or your child may not receive any direct benefit from participating in this study. The greatest benefit is that information gained from this study will contribute to research that may help other children with MDD. Research studies are essential in finding new and improved treatments and diagnostic tools.

Will I get all the facts about the study?

You as a participant, or as a parent interested in having your child participate, will be given a consent form that thoroughly explains all of the details of the study. The form covers all of the procedures, the risks, the benefits, the pay, who to contact with questions or concerns and more. A member of the study staff will review the consent form with you and will be sure that all of your questions are answered. Study procedures will not begin until a parent or guardian has signed this form and, if of age, the child has given at minimum his/her verbal agreement.

What are the risks and discomforts of the study?

There are limited risks associated with the use of TMS. Based on previous studies involving both children and adults exposed to TMS, there may be mild and temporary side effects such as scalp discomfort, hand weakness and headaches.

A detailed list of possible side effects will be provided to those participants, parents or guardians interested in knowing more about this study.

Do participants receive pay, compensation or reimbursement?

Participants will receive $50 for this one-time study visit as reimbursement for their time and travel.


Cameron Laue
Cincinnati Children’s Hospital Medical Center
Division of Neurology
3333 Burnet Avenue
Cincinnati, OH 45229-3039

Study Doctor

Steve Wu, MD
Pediatric Neurologist
Cincinnati Children’s Hospital Medical Center
Division of Neurology