RELRB1: A Pilot Study of Intravenous Topotecan and Vincristine in Combination with Subconjunctival Carboplatin for Patients with a History of Bilateral Retinoblastoma and Refractory/Recurrent Intraocular Disease

What is the purpose of this study?

The investigators are testing intravenous topotecan and vincristine in combination with subtenon carboplatin in the hopes of finding a drug combination that may be effective against retinoblastoma that has come back or is resistant to other treatment.


  • Cancer - Retinoblastoma
  • Medications


Cincinnati Children’s Hospital Medical Center
Cancer and Blood Diseases Institute
3333 Burnet Ave., Cincinnati, OH 45229-3039
Phone: 513-636-2799