Show All

Colorectal Surgery

Andrea Bischoff, MD
Pediatric Surgeon, Colorectal Center for Children

513-636-3240

andrea.bischoff@cchmc.org

High Res

Andrea Bischoff, MD

Pediatric Surgeon, Colorectal Center for Children

Instructor, Division of Pediatric Surgery

Phone: 513-636-3240

Fax: 513-636-3248

Email: andrea.bischoff@cchmc.org

Show All

Specialties

Colorectal surgery; pediatric surgery; anorectal malformation; Hirschsprung disease; total colonic aganglionosis; bowel management (fecal incontinence and idiopathic constipation).

Biography

Andrea Bischoff is a pediatric surgeon for the Colorectal Center at Cincinnati Children’s Hospital Medical Center. She earned her medical degree at University of Brasilia – Brasilia, Brazil. Her general surgery residency and pediatric surgical fellowship were completed at Brasilia University Hospital - Brasilia, Brazil. On October 2007 she joined the Colorectal Center at Cincinnati Children’s Hospital Medical Center for a two-year research fellowship followed by two years of clinical fellowship. In March 2012 she joined the staff as a full-time member of the Colorectal Center for Children.

Education and Training

MD: University of Brasilia, Brasilia, Brazil.

Residency: Brasilia University Hospital, Brasilia, Brazil.

Pediatric Surgery Fellowship: Brasilia University Hospital, Brasilia, Brazil.

Research and International Fellowship: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Publications

View PubMed Publications

Bischoff A, Calvo-Garcia MA, Baregamian N, Levitt MA, Lim FY, Hall J, Peña A. Prenatal Counseling for Cloaca and Cloacal Exstrophy – Challenges faced by Pediatric Surgeons. Pediatr Surg Intl. 2012;28:781-8.

Bischoff A, Levitt MA, Peña A. Total Colonic Aganglionosis: A Surgical Challenge. How to Avoid Complications?Pediatr Surg Int. 2011;27(10): 1047-52.

Peña A, Bischoff A, Levitt MA. The Transpubic Approach for Complex Anorectal and Urogenital Malformations. J Pediatr Surg. Dec 2011;46(12): 2316-20.

Bischoff A, Levitt MA, Peña A. Laparoscopy and its use in the Repair of Anorectal Malformations. J Pediatr Surg. 2011;46(8): 1609-17.

Levitt MA, Bischoff A, Peña A. Pitfalls and Challenges of Cloaca Repair; How to Reduce the Need for Reoperations. J Pediatr Surg. Jun 2011;46(6): 1250-1255.

Bischoff A, Levitt MA, Lawal TA, Peña A. Colostomy closure: how to avoid complications. Pediatr Surg Int. Nov 2010;26(11): 1087-92.

Bischoff A, Levitt MA, Breech L, Louden E, Peña A. Hydrocolpos in Cloacal Malformations. J Pediatr Surg. 2010;45(6): 1241-1245.

Peña A, Bischoff A, Breech L, Louden E, Levitt MA. Posterior Cloaca – Further Experience and Guidelines for the Treatment of an Unusual Anorectal Malformation. J Pediatr Surg. 2010;45(6): 1234-1240.

Bischoff A, Tovilla M. A Practical Approach to the Management of Pediatric Fecal Incontinence. Semin Pediatr Surg. 2012;19(2): 154-159.

Bischoff A, Levitt MA, Peña A. Bowel Management for the Treatment of Pediatric Fecal Incontinence. Pediatr Surg Int. 2009;25(12):1027-42.

Jason S. Frischer, MD
Director, Extracorporeal Membrane Oxygenation Program, Division of Pediatric General and Thoracic Surgery

513-636-4371

jason.frischer@cchmc.org

High Res

Jason S. Frischer, MD

Director, Extracorporeal Membrane Oxygenation Program, Division of Pediatric General and Thoracic Surgery

Assistant Professor, UC Department of Surgery

Phone: 513-636-4371

Fax: 513-636-7657

Email: jason.frischer@cchmc.org

Show All

Specialties

Colorectal surgery including Inflammatory Bowel Disease (IBD, Crohn's disease and Ulcerative Colitis); ECMO; congenital diaphragmatic hernia (CDH); neonatal surgery; minimally invasive surgery; Epidermolysis Bullosa (EB)

Biography

Jason S. Frischer, MD, is an assistant professor in the Division of Pediatric General and Thoracic Surgery at Cincinnati Children's Hospital Medical Center. He earned his medical degree at SUNY Downstate Medical Center. His surgical internship and general surgery residency were completed at the Mount Sinai School of Medicine in New York. Additionally, he spent two years as an ECMO fellow and a postdoctoral research fellow in tumor biology at the Children’s Hospital of New York, Columbia University. He went on to complete his pediatric surgery training at the Children’s Hospital of New York, Columbia University.

Dr. Frischer has a special interest in colorectal surgery including Inflammatory Bowel Disease (IBD, Crohn's disease and Ulcerative Colitis), Hirschsprung’s disease and anorectal malformations (ARM) and is member of the Colorectal Center as well as the Epidermolysis Bullosa (EB) Center. He serves as the director of the ECMO program and is a member of the congenital diaphragmatic hernia (CDH) team. He has an interest in neonatal surgery and laparoscopy.

Dr. Frischer is a member of Alpha Omega Alpha (national medical honor society) and was selected by Cincy Magazine Best Doctors in 2010 and 2011. He also was selected by Castle Connolly Medical Ltd. and U.S. News & World Report “Top Doctors” in 2012.

Education and Training

BS: Cornell University, Ithaca, NY, 1995.

MD: SUNY Downstate Medical Center, Brooklyn, NY, 1999.

Residency: Mount Sinai School of Medicine, The Mount Sinai Hospital, New York, NY, 2000-2001 and 2003-2006.

ECMO/Research Fellowship: Children's Hospital of New York - Presbyterian, Columbia University, New York, NY, 2001-2003.

Pediatric Surgery Residency: Children's Hospital of New York – Presbyterian, Columbia University, New York, NY, 2006-2008.

Certification: General Surgery, 2007; Pediatric Surgery, 2010.

Publications

View PubMed Publications

Chernoguz A, Crawford, K, Vandersall A, Willson T, Denson LA, Frischer JS. Pre-treatment with Anti-VEGF therapy may exacerbate inflammation in experimental acute colitis. J Pediatr Surg. 2012 Feb;47(2):347-54.

Le LD, Keswani SG, Biesiada J, Lim FY, Kingma PS, Haberman BE, Frischer J, Habli M, Crombleholme TM. The congenital diaphragmatic hernia composite prognostic index correlates with survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2012 Jan;47(1):57-62.

Lawal TA, Falcone RA, von Allmen D, Denson LA, Levitt MA, Warner BW, Frischer JS. The utility of routine pouchogram before ileostomy reversal in children and adolescents following ileal pouch anal anastomosis. J Pediatr Surg. 2011 Jun;46(6):1222-5.

Chernoguz A, Crawford KM, Donovan EC, Vandersall AE, Berglund C, Cripe TP, Frischer JS. EGFR Inhibition Fails to Suppress Vascular Proliferation and Tumor Growth in a Ewing’s Sarcoma Model. J Surg Res. 2012 Mar;173(1):1-9.

Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn’s disease. J Laparoendosc Adv Surg Tech A. 2010 Nov;20(9):791-5.

Bischoff A, Gupta A, D’Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn’s disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer JS, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

Frischer JS, Lee A, Serur A, Huang J, Bae JO, Kornfield ZN, Eljuga L, Shawber CJ, Feirt N, Mansukhani M, Stempak D, Baruchel S, Bender JG, Kandel JJ, Yamashiro DJ. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. Cancer Res. 2006 Apr;66(8):4378-84.

Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O’Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. Int J Onc. 2004 Sep;25(3):549-53.

Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O’Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc Natl Acad Sci USA. 2003 June 24;100(13):7785-90.

Michael A. Helmrath, MD, MS
Surgical Director, Intestinal Rehabilitation Program

513-636-4371

michael.helmrath@cchmc.org

High Res

Michael A. Helmrath, MD, MS

Surgical Director, Intestinal Rehabilitation Program

Director of Surgical Research

Professor, UC Department of Surgery

Phone: 513-636-4371

Email: michael.helmrath@cchmc.org

Show All

Biography

As a pediatric surgeon, Dr. Helmrath has dedicated his career to the care of patients with intestinal failure. The main focus of his laboratory is directed towards characterizing intestinal stem cells during intestinal adaptation and developing intestinal regenerative strategies. By combining his clinical experience as the surgical director of intestinal research and rehabilitation at Cincinnati Children’s Hospital, his long-term goal is to establish translational therapies for the management of patients with short bowel syndrome.

Education and Training

BA: Miami University, Oxford, OH, 1987.

MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.

MS: University of Cincinnati College of Medicine, Cincinnati, OH, 1989.

Certification: Board-certified General Surgery; board-certified, Pediatric Surgery.

Publications

View PubMed Publications

Helmrath MA, Shin CE, Fox JW, Erwin CR, Warner BW. Adaptation after small bowel resection is attenuated by sialoadenectomy: The role for endogenous epidermal growth factor. Surgery. 1998;124 (5):848-854.

Erwin CR, Helmrath MA, Shin CE, Falcone RA Jr., Stern LE, Warner BW. Intestinal overexpression of EGF in transgenic mice enhances adaptation after small bowel resection. Am J Physiol Gastrointest Liver Physiol. 1999;277:G533-G540.

Helmrath MA, Fong JJ, Dekaney CM, Henning SJ. Rapid expansion of intestinal secretory lineages following a massive small bowel resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007;292(1): G215-222.

Shroyer NF, Helmrath MA, Wang YYC, Antalffy B, Henning SJ, Zoghbi HY. Intestine specific ablation of Math 1 in mice reveals a role in cellular homeostasis. Gastroenterology. 2007;132(7):2478-2488.

Dekaney CM, Fong JJ, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Expansion of intestinal stem cells associated with long-term adaptation following ileocecal resection in mice. Am J Physiol Gastrointest Liver Physiol. 2007;293(5): G1013-22.

Dekaney CM, von Allmen DC, Garrison AP, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileocecal resection. Surgery. 2008;144(2):174-81.

Garrison AP, Dekaney CM, von Allmen DC, Lund PK, Henning SJ, Helmrath MA. Early but not late administration of glucagons-like peptide-2 following ileocecal resection augments putative intestinal stem cell expansion. Am J Physiol Liver Physiol. 2009;296(3): G643-50.

Rigby RJ, Hunt MR, Scull BP, Simmons JG, Speck KE, Helmrath MA, Lund PK. A new animal model of postsurgical bowel inflammation and fibrosis: the effect of commensal microflora. Gut. 2009;58(8);1104-12.

Garrison AP, Helmrath MA, Dekaney CM. Intestinal Stem Cells. J Pediatr Gastroenterol Nutr. 2009;49(1):2-7.

Speck KE, Garrison AP, Rigby RJ, von Allmen DC, Lund PK, Helmrath MA. Inflammation enhances resection-induced intestinal adaptive growth in IL-10 null mice. J Surg Research. 2011;168(1):62-69.

Grants

Mechanisms of intestinal stem cell expansion following resection. Principal Investigator. National Institute of Diabetes and Digestive and Kidney Disease. Jul 2009 - June 2014. #R01DK083325.

Collaborative approach to the study of intestinal epithelial stem cells. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. Sep 2009 - Aug 2014. #1U01DK085547.

Neointestine from live donors & pluripotent stem cells. Co-investigator. CCST University of Cincinnati. 07/01/11 – 06/30/11.

Adolescent Bariatrics: Assessing Health Benefits & Risk. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. 11/01/11 – 10/31/16. U01 DK072493.

Human Endocrine Cell Development. Co-investigator. National Institute of Diabetes and Digestive and Kidney Diseases. 04/01/12 – 03/31/17. R01 DK092456.

Belinda Hsi Dickie, MD, PhD
Colorectal Center

513-636 3240

belinda.dickie@cchmc.org

High Res

Belinda Hsi Dickie, MD, PhD

Colorectal Center

Assistant Professor, UC Department of Pediatrics

Phone: 513-636 3240

Email: belinda.dickie@cchmc.org

Show All

Specialties

Colorectal surgery; vascular malformations; minimally invasive surgery; general pediatric surgery

Biography

Belinda Hsi Dickie, MD, PhD, is an assistant professor with the Division of Pediatric General and Thoracic Surgery at Cincinnati Children's Hospital Medical Center. She obtained her medical degree at the University of Toronto, Ontario Canada and subsequently did her general surgery residency, and completed her PhD, at the University of Alberta, Alberta, Canada. Dr. Dickie continued her training at the University of Alberta, with a fellowship in advanced minimally invasive surgery. She then relocated to the United States where she continued her training and completed fellowships in pediatric vascular malformations and pediatric colorectal surgery at Cincinnati Children’s Hospital Medical Center. She has recently completed her training in pediatric surgery at the University of Florida. She was recruited back to Cincinnati Children’s Hospital in 2011.

Dr. Hsi Dickie has a special interest in the medical and surgical treatment of vascular malformations, pediatric colorectal surgery (including Hirschsprung’s Disease, inflammatory bowel disease, anorectal malformations) and minimally invasive surgery. She also has a lab in vascular biology looking at the genetics and molecular pathways involved with lymphangiogenesis, and the development of vascular malformations

Education and Training

MD: University of Toronto, Toronto,Ontario, Canada 1998.

Residency: General Surgery, University of Alberta, Edmonton, Alberta, Canada.

Fellowship: Advanced Minimally Invasive Surgery, University of Alberta, Edmonton, Alberta, Canada; Vascular anomalies, Cincinnati Children's, Cincinnati, OH; Pediatric Colorectal Surgery, Cincinnati Children's, Cincinnati, OH; Pediatric Surgery, University of Florida Gainesville, Florida,

Certification: General Surgery, 2006; Pediatric Surgery, 2011.

Publications

View PubMed Publications

Levitt MA, Dickie B, Peña A. Evaluation and treatment of the patient with Hirschsprung disease who is not doing well after a pull-through procedure. Semin Pediatr Surg. 2010 May;19(2):146-53.

Dickie B, Dasgupta R, Nair R, Alonso MH, Ryckman FC, Tiao GM, Adams DM, Azizkhan RG. Spectrum of hepatic hemangiomas: management and outcome. J Pediatr Surg. 2009 Jan;44(1):125-33.

Kneteman NM, Weiner AJ, O'Connell J, Collett M, Gao T, Aukerman L, Kovelsky R, Ni ZJ, Zhu Q, Hashash A, Kline J, Hsi B, Schiller D, Douglas D, Tyrrell DL, Mercer DF. Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application. Hepatology. 2006 Jun;43(6):1346-53.

Hao C, Song JH, Hsi B, Lewis J, Song DK, Petruk KC, Tyrrell DL, Kneteman NM. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 2004 Dec 1;64(23):8502-6.

Hsu EC, Hsi B, Hirota-Tsuchihara M, Ruland J, Iorio C, Sarangi F, Diao J, Migliaccio G, Tyrrell DL, Kneteman N, Richardson CD. Modified apoptotic molecule (BID) reduces hepatitis C virus infection in mice with chimeric human livers. Nat Biotechnol. 2003 May;21(5):519-25.

Marc A. Levitt, MD
Director, Colorectal Center

513-636-3240

marc.levitt@cchmc.org

High Res

Marc A. Levitt, MD

Director, Colorectal Center

Professor, Division of Pediatric Surgery

Phone: 513-636-3240

Fax: 513-636-3248

Email: marc.levitt@cchmc.org

Show All

Specialties

Pediatric colorectal surgery; pediatric minimally invasive surgery

Biography

Dr. Levitt is the director of the Colorectal Center for Children at Cincinnati Children's Hospital Medical Center. He joined the full-time staff at Cincinnati Children's Hospital Medical Center in June 2005 when he and Dr. Peña were recruited to create the world’s first and only multidisciplinary and comprehensive Colorectal Center for Children.

Dr. Levitt received his undergraduate degree from the University of Pennsylvania, and his medical degree from the Albert Einstein College of Medicine, where he was elected to the Alpha Omega Alpha Society and worked with Dr. Peña as a medical student in 1992. Dr. Levitt completed his general surgery residency at the Mount Sinai Medical Center in New York and also served as a clinical and research fellow in pediatric colorectal surgery with Dr. Peña at Schneider Children's Hospital. He completed his pediatric surgery fellowship at the Children's Hospital of Buffalo, and was a pediatric surgical attending there, serving as the clinical director of their Pediatric Miniature Access Surgery Center, from 1999 to 2002. He was faculty at the Albert Einstein College of Medicine and Pediatric Surgeon at Schneider Children’s Hospital, North Shore Long Island Jewish Health System from 2002 to 2005.

Education and Training

MD: Albert Einstein College of Medicine.

Residency: Surgery, Mount Sinai Medical Center, New York.

Fellowhip: Pediatric Surgery, Children's Hospital of Buffalo.

Certification: Surgery; Pediatric Surgery.

Publications

View PubMed Publications

Livingston JC, Elicevik M, Breech L, Crombleholme TM, Peña A, Levitt MA. Persistent Cloaca: A 10-Year Review of Prenatal Diagnosis. Journal of Ultrasound in Medicine. 2012.

Hamrick M, Eradi B, Bischoff A, Louden E, Peña A, Levitt MA. Rectal Atresia and Stenosis; Unique Anorectal Malformations. J Pediatr Surg. 2012;47(6): 1280-4.

Chatoorgoon K, Peña A, Lawal TA, Louden E, Levitt MA. The Problematic Duhamel Pouch in Hirschsprung’s Disease: Manifestations and Treatment. European Journal of Pediatric Surgery. 2011;21: 366-9.

Bischoff A, Levitt MA, Peña A. Total Colonic Aganglionosis – A Surgical Challenge: How to Avoid Complications. Pediatr Surg Int. 2011 Oct;27(10): 1047-52.

Podberesky DJ, Weaver NC, Anton CG, Lawal T, Hamrick MC, Alam S, Peña A, Levitt MA. MRI of Acquired Posterior Urethral Diverticulum Following Surgery for Anorectal Malformations. Pediatr Radiol. 2011 Sept;41(9): 1139-1145.

Rangel SJ, Lawal TA, Bischoff A, Chatoorgoon K, Louden E, Peña A, Levitt MA. The Appendix as a Conduit for Antegrade Continence Enemas in Patients with Anorectal Malformations: Lessons Learned from 163 Cases treated over 18 years. J Pediatr Surg. 2011 Jun;46(6): 1236-42.

Alam S, Lawal TA, Peña A, Sheldon C, Levitt MA. Acquired Posterior Urethral Diverticulum Following Surgery for Anorectal Malformations. 2010 Jun;J Pediatr Surg. 46(6): 1231-5.

Chatoorgoon K, Peña A, Lawal TA, Hamrick M, Louden E, Levitt MA. Neoappendicostomy in the Management of Pediatric Fecal Incontinence. J Pediatr Surg. 2011 Jun;46(6): 1243-49.

Bischoff A, Levitt MA, Peña A. Laparoscopy and its use in the Repair of Anorectal Malformations. J Pediatr Surg. 2011;46(8): 1609-17.

Ebony Moorefield, APRN
Pediatric Nurse Practitioner, Colorectal Center

513-636-9451

ebony.moorefield@cchmc.org

Alberto Peña, MD
Founding Director, Colorectal Center

513-636-3240

alberto.pena@cchmc.org

High Res

Alberto Pena, MD

Founding Director, Colorectal Center

Professor, Division of Pediatric Surgery

Phone: 513-636-3240

Fax: 513-636-3248

Email: alberto.pena@cchmc.org

Show All

Specialties

Clinical research regarding colorectal problems in children

Biography

Alberto Peña, MD, director of the Colorectal Center, at Cincinnati Children's, received his medical degree at the Military Medical School in Mexico City, in 1962.

Dr. Peña trained in general surgery and medical pediatrics at the Central Military Hospital, finishing in 1968. From 1969 until December 1971, he trained at Boston Children's Hospital.

Dr. Peña moved back to Mexico City as the surgeon-in-chief of the National Institute of Pediatrics from January 1972 until June 1985.

Dr. Peña joined the full-time staff at Schneider Children's Hospital in July 1985 and was the chief of Pediatric Surgery and professor of Surgery at the Albert Einstein College of Surgeons.

In 1982, Dr. Peña described a new approach for the management of anorectal malformations: Posterior Sagittal Anoplasty / PSARP, also known as the Pull-Through Procedure.

Since 1982 until the present, Dr. Peña has been traveling all over the world, lecturing and operating on children affected by this particular malformation.

At the present time, Dr. Peña dedicates 80 percent of his time to the treatment of anorectal problems in children.

Seventy percent of the patients operated on by Dr. Peña at Cincinnati Children's come from other states and from all over the world.

Education and Training

MD: Military Medical School, Mexico City, Mexico, 1962.

Residency: Central Military Hospital, Mexico City, Mexico, 1966; Children's Hospital Medical Center, Boston, MA, 1969-1971.

Publications

View PubMed Publications

Lawal TA, Rangel SJ, Bischoff A, Peña A, Levitt MA. Laparoscopic-Assisted Malone Appendicostomy in the Management of Fecal Incontinence in Children. J Laparoendosc Adv Surg Tech A. 2011 Mar 2.

Lawal TA, Chatoorgoon K, Collins MH, Coe A, Peña A, Levitt MA. Redo pull-through in Hirschsprung's disease for obstructive symptoms due to residual aganglionosis and transition zone bowel. J Pediatr Surg. 2011 Feb;46(2):342-7.

Bischoff A, Levitt MA, Lim FY, Guimarães C, Peña A. Prenatal diagnosis of cloacal malformations. Pediatr Surg Int. 2010 Nov;26(11):1071-5.

Bischoff A, Levitt MA, Lawal TA, Peña A. Colostomy closure: how to avoid complications. Pediatr Surg Int. 2010 Nov;26(11):1087-92.

Bischoff A, Levitt MA, Breech L, Louden E, Peña A. Hydrocolpos in cloacal malformations. J Pediatr Surg. 2010 Jun;45(6):1241-5.

Peña A, Bischoff A, Breech L, Louden E, Levitt MA. Posterior cloaca--further experience and guidelines for the treatment of an unusual anorectal malformation. J Pediatr Surg. 2010 Jun;45(6):1234-40.

Levitt MA, Kant A, Peña A. The morbidity of constipation in patients with anorectal malformations. J Pediatr Surg. 2010 Jun;45(6):1228-33.

Levitt MA, Peña A. Minimally invasive treatment of fecal incontinence and constipation in children. Minerva Chir. 2010 Apr;65(2):223-34. Review.

Levitt MA, Dickie B, Peña A. Evaluation and treatment of the patient with Hirschsprung disease who is not doing well after a pull-through procedure. Semin Pediatr Surg. 2010 May;19(2):146-53.

Levitt MA, Peña A. Cloacal malformations: lessons learned from 490 cases. Semin Pediatr Surg. 2010 May;19(2):128-38.

Daniel von Allmen, MD
Director, Division of General and Thoracic Surgery

513-636-4371

daniel.vonallmen@cchmc.org

Daniel von Allmen, MD

Director, Division of General and Thoracic Surgery

Professor, Division of Pediatric Surgery

Phone: 513-636-4371

Email: daniel.vonallmen@cchmc.org

Show All

Specialties

Clinical Interests

Pediatric surgical oncology; pediatric inflammatory bowel disease; surgical innovation; surgical robotics

Research Interests

Oncology; innovation; surgical workforce

Biography

Daniel von Allmen, MD, comes to Cincinnati from Chapel Hill, NC where he was the Surgeon-in-Chief and Division Chief at the North Carolina Children’s Hospital.

Dr. von Allmen completed his general surgery training at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center. He is currently the Program Committee chair of the American Pediatric Surgical Association. He also serves on the Program Committee for the American Academy of Pediatrics Surgical Section and is a member of the Steering Committee for the Surgical Section of the Children’s Oncology Group.

Dr. von Allmen's special clinical interests include pediatric surgical oncology, pediatric inflammatory bowel disease, surgical innovation, and surgical robotics.

Education and Training

MD: University of Vermont College of Medicine.

Residency: General Surgery, University of Cincinnati, Cincinnati, OH.

Fellowship: Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.

Certifications: General Surgery, Pediatric Surgery.

Publications

Mayer ML, Beil HA, von Allmen D. Distance to care and relative supply among pediatric surgical subspecialties. J Pediatr Surg. 2009;44:483-495.

Colorectal Staff

Kennethia C. Banks-Borden
Administrative Assistant, Colorectal Center

513-636-3240

kennethia.banks-borden@cchmc.org

Cathy L. Bauer, RN, CPN
Registered Nurse, Colorectal Center

513-636-3242

cathy.bauer@cchmc.org

Giulia Brisighelli, MD
Research Fellow, Colorectal Center

513-803-0514

giulia.brisighelli@cchmc.org

Kimberly E. Cain, RN, MSN, CNP, CWOCN
Nurse Practitioner, Colorectal Center

513-803-1161

kimberly.cain@cchmc.org

Pam D. Faulkner, CMA, CPC
Financial Service Representative III, Colorectal Center

513-636-2268

pam.faulkner@cchmc.org

Jennifer M. Hall, RN, MN, BSME
Research Nurse, Colorectal Center

513-636-3246

jennifer.hall@cchmc.org

Michelle A. B. Hathorn, BA
Administrative Assistant, Colorectal Center

513-803-0063

michelle.hathorn@cchmc.org

Tori Hiudt
Administrative Assistant, Colorectal Center

513-636-3240

tori.hiudt@cchmc.org

Monica M. Holder, RN, BSN, CNP
Registered Nurse, Colorectal Center

513-636-3241

monica.holder@cchmc.org

Mikeisha S. Isome, BA
Administrative Assistant, Colorectal Center

513-636-3240

mikeisha.isome@cchmc.org

Lyndsey Jackson, RN, BSN, CPN
Registered Nurse, Colorectal Center

513-803-0258

lyndsey.jackson@cchmc.org

Patricia Kern, RN, BSN
Registered Nurse, Colorectal Center

513-636-9203

patricia.kern@cchmc.org

Dana Koehler, RN
Registered Nurse, Colorectal Center

513-803-0258

dana.koehler@cchmc.org

Teri S. Martini, RN, BSN
Program Manager, Colorectal Center

513-803-7327

teri.martini@cchmc.org

Gretchen J. Niebling, CAPPM, CPC
Administrative Supervisor, Colorectal Center

513-803-0228

gretchen.niebling@cchmc.org

Tiffany L. Poor, MA
Medical Assistant, Colorectal Center

513-803-1677

tiffany.poor@cchmc.org

Amy L. Powell
Administrative Assistant, Colorectal Center

513-803-2042

amy.powell@cchmc.org

Inbal Samuk, MD
Clinical Fellow, Colorectal Center

513-636-3240

inbal.samuk@cchmc.org

Inbal Samuk, MD

Clinical Fellow, Colorectal Center

University of Cincinnati College of Medicine

Phone: 513-636-3240

Email: inbal.samuk@cchmc.org

Show All

Specialties

Anorectal malformations

Biography

Inbal Samuk, MD, received his doctorate degree from Tel Aviv University in 1993. Dr. Samuk completed his general surgery training at Assaf Harofeh Medical Center, and subsequently was trained as a pediatric surgeon at Schneider Children’s Medical Center in Israel. He is board certified in general surgery by the Israel Surgical Board.

Education and Training

MD: Sackler school of Medicine, Tel Aviv University, Israel 1993.

Residency: General Surgery, Assaf Harofeh Medical Center, Israel; Pediatric Surgery, Schneider Children’s Medical Center, Israel.

Certification: Israel Surgical Board, General Surgery 2006.

Publications

View PubMed Publications

Halevy A, Samuk I, Halpern Z, Copel L, Sandbank J, Ziv Y. Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor desmoids tumor. Tech Coloproctol. 2010;14:265-267.

Samuk I, Afriate R, Horne T, et al. Dumping syndrome following Nissen fundoplication, diagnosis and treatment. J Pediatr Gastroenterology Nutr. 1996;23:235-240.

Samuk I, Efrati Y, Klin B, Vinograd I, et al. Nissen fundoplication for the management of gastroesophageal reflux in children. Harefuah. 1994;126:311-315.

Christina Eby Stewart, MSW, LISW-S
Social Worker II, Colorectal Center

513-636-3247

christina.stewart@cchmc.org

Anesthesia

Lori A. Aronson, MD
Staff Anesthesiologist

513-636-4408

lori.aronson@cchmc.org

Lori A. Aronson, MD, is a staff anesthesiologist in the Department of Anesthesia at Cincinnati Children's Hospital Medical Center.

High Res

Lori Aronson, MD

Staff Anesthesiologist

Associate Professor, Division of Pediatric Anesthesia

Phone: 513-636-4408

Fax: 513-636-7337

Email: lori.aronson@cchmc.org

Show All

Specialties

Clinical Interests

Cardiac anesthesia; regional anesthesia; anesthesia for airway surgery

Biography

Dr. Aronson's practice interests include pediatric cardiac and regional anesthesia. She is also interested in the role of antifibrinolytics for large blood loss cases.

Dr. Aronson is Cincinnati Children's Anesthesia Resident Education Coordinator and is actively involved in resident and fellow education.

Education and Training

MD: University of Illinois, Chicago, IL, 1994.

Residency: Anesthesiology, University of North Carolina Hospitals, Chapel Hill, NC, 2000.

Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, OH, 1997.

Fellowship: Pediatric Anesthesiology, University of North Carolina Hospitals, Chapel Hill, NC.

Certification: Pediatrics, 1997; Anesthesiology, 2001; Cardiac Anesthesia.

Publications

View PubMed Publications

Lin EP, Aronson LA. Successful resuscitation of bupivacaine-induced cardiotoxicity in a neonate. Paediatr Anaesth. 2010 Oct;20(10):955-7.

Aronson, LA; Spaeth, J.P.: Frontiers in Pediatric Anesthesia: Cardiac Anesthesia. International Anesthesiology Clinics: Frontiers in Pediatric Anesthesiology. Winter 2006; 44(1):33-49.

Aronson, LA; Dent, C.L.: Postoperative Respiratory Function and Its Management. Pediatric Cardiac Anesthesia. 2005.

Book Chapters

Aronson LA. Pediatrics and Neonatology: Hypoxemia. Complications in Anesthesia. Ed: John L Atlee, 2nd ed, 2007.

Anne Boat, MD
Staff Anesthesiologist

513-636-4408

anne.boat@cchmc.org

Nancy S. Hagerman, MD

nancy.hagerman@cchmc.org

Mario Patino, MD
Anesthesiologist

513-636-4408

mario.patino@cchmc.org

James P. Spaeth, MD
Director, Cardiac Anesthesia

513-636-4408

james.spaeth@cchmc.org

High Res

James P. Spaeth, MD

Director, Cardiac Anesthesia

Staff Anesthesiologist

Associate Professor, Division of Pediatric Anesthesia

Phone: 513-636-4408

Fax: 513-636-7337

Email: james.spaeth@cchmc.org

Show All

Specialties

Cardiac anesthesia; neurologic injury in children with congenital heart disease; improving perioperative safety

Education and Training

MD: University of Virginia School of Medicine, Charlottesville, VA, 1993.

Internship: Internal Medicine, University of Virginia Medical Center, Charlottesville, VA, 1994.

Residency: Anesthesiology, University of California, San Diego Medical Center, San Diego, CA, 1997.

Fellowship: Pediatric Anesthesiology, Children's Hospital of Philadelphia, Philadelphia, PA, 1998.

Certification: Anesthesiology, 1998.

Publications

View PubMed Publications

Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65.

Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2006 Jan;131(1):190-7.

Aronson LA, Spaeth JP. Frontiers in pediatric anesthesia: cardiac anesthesia. Int Anesthesiol Clin. 2006 Winter;44(1):33-49.

Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2005 Dec;130(6):1523-30.

Loepke AW, Spaeth JP. Glucose and Heart Surgery: Neonates Are Not Just Small Adults. Anesthesiology. 2004 Jun;100(6):1345-52.

Baker RC, Schubert CJ, Kirwan KA, Lenkauskas SM, Spaeth JT. After-hours telephone triage and advice in private and nonprivate pediatric populations. Arch Pediatr Adolesc Med. 1999 Mar;153(3):292-6.

Anna M. Varughese, MD, MPH
Associate Director, Division of Anesthesia

513-636-4408

anna.varughese@cchmc.org

Anna M. Varughese, MD is a member of the anesthesia faculty and staff of Cincinnati Children's Hospital Medical Center.

High Res

Anna M. Varughese, MD, MPH

Associate Director, Division of Anesthesia

Associate Professor, Division of Pediatric Anesthesia

Phone: 513-636-4408

Fax: 513-636-7337

Email: anna.varughese@cchmc.org

Show All

Specialties

Clinical Interests

Pain management; anesthesia for spine surgery; neonatal anesthesia

Research Interests

Postoperative pain management; clinical effectiveness in anesthesia care

Education and Training

MD: Madras University, Vellore, India, 1989.

Residency: Anesthesiology, Christian Medical College Hospital, Vellore, India, 1989; Anesthesiology, Queen Elizabeth Hospital, Birmingham, England, 1994; Anesthesiology, University of Cincinnati, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1995.

Fellowship: Pediatric Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1996.

Certification: American Board of Anesthesiology, 1996.

DA: Anesthesia, Madras, India, 1988.

FRCA: Fellowship of the Royal College of Anesthetists, United Kingdom, 1993.

MPH: Master in Public Health, Harvard School of Public Health, Boston, MA, 2003-2005.

Publications

View PubMed Publications

Varughese AM, Hagerman NS, Kurth CD. Quality in pediatric anesthesia. Paediatr Anaesth. 2010 Aug;20(8):684-96.

Sadhasivam S, Cohen LL, Hosu L, Gorman KL, Wang Y, Nick TG, Jou JF, Samol N, Szabova A, Hagerman N, Hein E, Boat A, Varughese A, Kurth CD, Willging JP, Gunter JB. Real-time assessment of perioperative behaviors in children and parents: development and validation of the perioperative adult child behavioral interaction scale. Anesth Analg. 2010 Apr 1;110(4):1109-15.

König MW, Varughese AM, Brennen KA, Barclay S, Shackleford TM, Samuels PJ, Gorman K, Ellis J, Wang Y, Nick TG. Quality of recovery from two types of general anesthesia for ambulatory dental surgery in children: a double-blind, randomized trial. Paediatr Anaesth. 2009 Aug;19(8):748-55.

Sadhasivam S, Cohen LL, Szabova A, Varughese A, Kurth CD, Willging P, Wang Y, Nick TG, Gunter J. Real-time assessment of perioperative behaviors and prediction of perioperative outcomes. Anesth Analg. 2009 Mar;108(3):822-6.

Varughese AM, Nick TG, Gunter J, Wang Y, Kurth CD. Factors predictive of poor behavioral compliance during inhaled induction in children. Anesth Analg. 2008 Aug;107(2):413-21.

Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65.

Varughese AM, Byczkowski TL, Wittkugel EP, Kotagal U, Dean Kurth C. Impact of a nurse practitioner-assisted preoperative assessment program on quality. Paediatr Anaesth. 2006 Jul;16(7):723-33.

Wittkugel EP, Varughese AM. Pediatric preoperative evaluation--a new paradigm. Int Anesthesiol Clin. 2006 Winter;44(1):141-58.

Varughese AM, Morillo-Delerme J, Kurth CD. Quality management in the delivery of pediatric anesthesia care. Int Anesthesiol Clin. 2006 Winter;44(1):119-39.

Child Life Services

Courtney N. Tyra, MS, CCLS
Child Life Specialist, Division of Child Life

513-636-8998

courtney.tyra@cchmc.org

Gastroenterology / Motility

Lee A. Denson, MD
Medical Director, Inflammatory Bowel Disease Center

513-636-7575

lee.denson@cchmc.org

High Res

Lee A. Denson, MD

Medical Director, Inflammatory Bowel Disease Center

Associate Professor, UC Department of Pediatrics

Phone: 513-636-7575

Email: lee.denson@cchmc.org

Show All

Specialties

Inflammatory bowel disease; growth failure; celiac disease

Visit the Denson Lab.

Biography

The primary focus of Dr. Lee A. Denson's laboratory is to determine the molecular basis for alterations in growth hormone signaling in inflammatory bowel diseases (IBD).

Normal growth and development are dependent upon the ability of growth hormone to regulate IGF-1 expression. Evidence from studies in children with IBD and mouse models of colitis indicates that inflammatory cytokines which are up regulated in this setting may cause an acquired GH resistance. Consequences may include growth failure, altered body composition and impaired mucosal healing.

We are using complementary experimental and patient-based approaches to investigate regulation of growth hormone signaling in mouse models of colitis and in children with Crohn's disease. These include down regulation of the growth hormone receptor and up regulation of a family of post-receptor inhibitory proteins, the Suppressors of Cytokine Signaling (SOCS). These studies should lead to the development of more effective therapies for children with IBD and other chronic inflammatory conditions.

Education and Training

MD: Medical College of Virginia, Richmond, VA, 1993

Residency: Yale-New Haven Hospital, New Haven, CT, 1993-96.

Certification: Pediatrics, 1996 & 2002.

Fellowship: Yale University School of Medicine, New Haven, CT, 1996-99.

Publications

View PubMed Publications

Herzer M, Denson LA, Baldassano RN, Hommel KA. Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2011 Jan;23(1):95-100.

Gray WN, Denson LA, Baldassano RN, Hommel KA. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease. Inflamm Bowel Dis. 2010 Nov 4.

Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn's disease. J Laparoendosc Adv Surg Tech A. 2010 Nov;20(9):791-5.

Denson LA, Kim MO, Bezold R, Carey R, Osuntokun B, Nylund C, Willson T, Bonkowski E, Li D, Ballard E, Collins M, Moyer MS, Klein DJ. A randomized controlled trial of growth hormone in active pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2010 Aug;51(2):130-9.

Nylund CM, Denson LA, Noel JM. Bacterial enteritis as a risk factor for childhood intussusception: a retrospective cohort study. J Pediatr. 2010 May;156(5):761-5.

Ingerski LM, Baldassano RN, Denson LA, Hommel KA. Barriers to oral medication adherence for adolescents with inflammatory bowel disease. J Pediatr Psychol. 2010 Jul;35(6):683-91.

Tomer G, Wetzler G, Keddache M, Denson LA. Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients. J Pediatr Gastroenterol Nutr. 2009 May;48(5):531-7.

Uchida K, Nakata K, Suzuki T, Luisetti M, Watanabe M, Koch DE, Stevens CA, Beck DC, Denson LA, Carey BC, Keicho N, Krischer JP, Yamada Y, Trapnell BC. Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects. Blood. 2009 Mar 12;113(11):2547-56.

Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA. Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology. 2009 Apr;136(4):1261-71, e1-3.

Denson LA. Growth hormone therapy in children and adolescents: pharmacokinetic/pharmacodynamic considerations and emerging indications. Expert Opin Drug Metab Toxicol. 2008 Dec;4(12):1569-80. Review.

Jose M. Garza, MD, MS

513-636-4415

gastro@cchmc.org

Nephrology

John J. Bissler, MD
Associate Program Director for Research and Academic Careers

513-636-1201

john.bissler@cchmc.org

High Res

John J. Bissler, MD

Associate Program Director for Research and Academic Careers

Clark D. West Chair of Nephrology

Director, Nephrology Fellowship Training Program

Professor, UC Department of Pediatrics

Phone: 513-636-1201

Fax: 513-636-7407

Email: john.bissler@cchmc.org

Show All

Specialties

Clinical Interests

Proliferative renal diseases; renal cystic disease; solid lesions

Research Interests

Proliferative renal diseases; polycystic kidney disease; tuberous sclerosis complex; Von Hippel-Lindau disease; Birt-Hogg-Dube syndrome and renal cancers; understanding the mechanisms of mutation leading to these diseases as well as the consequences of mutations in hope of finding effected treatments

Visit the Bissler Lab.

Education and Training

MD: Northeastern Ohio University College of Medicine, Rootstown, OH, 1985

Residency: Pediatrics, Children's Medical Center, Akron, OH

Fellowship: Nephrology, Children's Hospital Medical Center, Cincinnati, OH

Certification: Pediatrics, 1989; Pediatric Nephrology, 1992

Publications

View PubMed Publications

Dixon BP, Hulbert JC, and Bissler JJ. Tuberous Sclerosis Complex Renal Disease. Nephron. 2011;118(1):e15-20.

Siroky BJ, Yin H, Bissler JJ. Molecular Insights into Tuberous Sclerosis Complex Renal Disease. Pediatric Nephrol. 2010 Dec 9.

Mrug M, and Bissler JJ. Simulation of real-time ultrasound-guided renal biopsy. Kidney Int. 2010 Oct;78(7):705-7.

Bissler JJ, Siroky BJ, Yin H. Glomerulocystic kidney disease. Pediatric Nephrol. 2010 Oct;25(10):2049-56; quiz 2056-9.

Liu G, Bissler JJ, Sinden RR, Leffak M. Replication dependent instability at (CTG)•(CAG) repeat hairpins in human cells. Nat Chem Biol. 2010 Sep;6(9):652-9.

Johnson SR, and the Review Panel of the European Respiratory Society Lymphangioleiomyomatosis Task Force. European Respiratory Society guidelines for the diagnosis and management of lymphangioleiomyomatosis. Eur Respir J. 2010;35:14-26.

Siroky BJ, Czyzyk-Krzeska MF, Bissler JJ. Renal involvement in tuberous sclerosis complex and von Hippel-Lindau disease: shared disease mechanisms? Nat Clin Pract Nephrol. 2009;5(3):143-56.

Schmithorst VJ, Altes TA, Young LR, Franz DN, Bissler JJ, McCormack FX, et al. Automated algorithm for quantifying the extent of cystic change on volumetric chest CT: initial results in Lymphangioleiomyomatosis . Am J Roentgenol. 2009;192(4):1037-44.

Dixon BP, Chu A, Henry J, Kim R, Bissler JJ. Increased cancer risk of augmentation cystoplasty: Possible role for hyperosmolal microenvironment on DNA damage recognition . Mutat Res. 2009; 670:88-95.

Book Chapters

Bissler JJ, Henske E. Tuberous Sclerosis Complex: From Genes to Therapeutics. Chapter 15. Renal Manifestations of Tuberous Sclerosis Complex. In: Whittemore V, Henske EP, Kwiatkowski D, editors. New York: Elsevier; 2009.

Grants

Placebo-Controlled Randomized Multicenter mTOR Inhibitor Trial for Angiomyolipomata. Principal Investigator. Jun 2006 – Jun 2014.

Jens W. Goebel, MD
Clinical Director, Nephrology and Hypertension

513-636-4531

jens.goebel@cchmc.org

High Res

Jens W. Goebel, MD

Clinical Director, Nephrology and Hypertension

Medical Director, Kidney Transplantation

Clinical Director, Kidney Transplantation

Associate Professor, UC Department of Pediatrics

Phone: 513-636-4531

Fax: 513-636-7407

Email: jens.goebel@cchmc.org

Show All

Specialties

Clinical Interests

Organ transplantation in children

Research Interests

Transplant-relevant immunology

Biography

Dr. Goebel was recruited by Cincinnati Children's Hospital Medical Center in 2002 from the University of Kentucky to enhance the institution's kidney transplant program. His efforts along these lines focus both on further improving the clinical care of pediatric kidney transplant recipients and their families, as well as advancing basic and translational investigations into immunological aspects especially relevant to the field of transplantation.

Education and Training

MD: University of Heidelberg (Germany), 1991.

Residency and Chief Residency: Department of Pediatrics, University of South Alabama, Mobile, AL, 1991 to 1995.

Fellowship: Section of Pediatric Nephrology, Tulane University Medical Center, New Orleans, LA, 1995 to 1998

Certifications: General Pediatrics, 1994, 2002; Pediatric Nephrology, 1999.

Publications

View PubMed Publications

Sanchez-Pinto LN, Laskin BL, Jodele S, Hummel TR, Yin HJ, Goebel J. BK virus nephropathy in a pediatric autologous stem-cell transplant recipient. Pediatr Blood Cancer. 2011 Mar;56(3):495-7.

Hooper DK, Carle AC, Schuchter J, Goebel J. Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals. Pediatr Transplant. 2011 Feb;15(1):88-95.

Sherwin CM, Fukuda T, Brunner HI, Goebel J, Vinks AA. The evolution of population pharmacokinetic models to describe the enterohepatic recycling of mycophenolic acid in solid organ transplantation and autoimmune disease. Clin Pharmacokinet. 2011 Jan 1;50(1):1-24.

Campbell K, Ng V, Martin S, Magee J, Goebel J, Anand R, Martz K, Bucuvalas J; SPLIT Renal Function Working Group. Glomerular filtration rate following pediatric liver transplantation--the SPLIT experience. Am J Transplant. 2010 Dec;10(12):2673-82.

Pai AL, Gray E, Kurivial K, Ross J, Schoborg D, Goebel J. The Allocation of Treatment Responsibility scale: a novel tool for assessing patient and caregiver management of pediatric medical treatment regimens. Pediatr Transplant. 2010 Dec;14(8):993-9.

Jodele S, Bleesing JJ, Mehta PA, Filipovich AH, Laskin BL, Goebel J, Pinkard SL, Davies SM. Successful early intervention for hyperacute transplant-associated thrombotic microangiopathy following pediatric hematopoietic stem cell transplantation. Pediatr Transplant. 2010 Nov 5.

Pai AL, Ingerski LM, Perazzo L, Ramey C, Bonner M, Goebel J. Preparing for transition? The allocation of oral medication regimen tasks in adolescents with renal transplants. Pediatr Transplant. 2011 Feb;15(1):9-16.

Laskin BL, Goebel J, Davies SM, Khoury JC, Bleesing JJ, Mehta PA, Filipovich AH, Paff ZN, Lawrence JM, Yin HJ, Pinkard SL, Jodele S. Early clinical indicators of transplant-associated thrombotic microangiopathy in pediatric neuroblastoma patients undergoing auto-SCT. Bone Marrow Transplant. 2010 Aug 9.

Herzer M, Goebel J, Cortina S. Transitioning cognitively impaired young patients with special health needs to adult-oriented care: collaboration between medical providers and pediatric psychologists. Curr Opin Pediatr. 2010 Oct;22(5):668-72.

Fukuda T, Goebel J, Thøgersen H, Maseck D, Cox S, Logan B, Sherbotie J, Seikaly M, Vinks AA. Inosine Monophosphate Dehydrogenase (IMPDH) Activity as a Pharmacodynamic Biomarker of Mycophenolic Acid Effects in Pediatric Kidney Transplant Recipients. J Clin Pharmacol. 2010 Apr 23.

Grants

Center-PI / Co-Investigator / Collaborator:

NIH UO1 grant: Noninvasive Monitoring to Predict Outcome in de novo Kidney Transplant Recipients (CTOT-01, Protocol Chair: P. Heeger, MD, City), commenced in late 2005 and ongoing

NIH UO1 grant: Health and Literacy in Child and Adult Assessment: Expanded Testing of the Pediatric PROMIS (Patient Reported Outcomes Measurement Information System) Tool (Sponsor: D. DeWalt, MD, MPH, ), ongoing

NIH UO1 grant: Chronic Kidney Disease in Children (CKID, PI: B. Warady, MD, Children’s Mercy Hospital, Kansas City, MO), ongoing

NIH RO1 grant: Calcineurin Inhibitor Minimization And Foxp3+ Tregs Post-Transplant (PIs: Wayne Hancock, MD, Children’s , and John Bucuvalas, MD, Cincinnati Children’s Hospital), ongoing

Midwest Pediatric Nephrology Consortium: Assessing and Implementing Transition to Adult Care in Children with CKD (PI: M. Ferris, MD, MPH, PhD, ), ongoing

Amgen Pharmaceuticals: Pediatric Anemia Correction Study (Protocol 20050256), ongoing

Roche Pharmaceuticals: Development of Population Pharmacokinetic models of Mycophenolic Acid for use in Bayesian Dose Individualization in Pediatric Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

Cincinnati Children’s Hospital Medical Center Outcomes Research Award: Validation of a Real-Time Adherence Assessment System (PI: A. Pai, PhD, Cincinnati Children’s Hospital), ongoing

Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Pharmacogenetics of Mycophenolic Acid in Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Biomarkers for Patient-tailored Therapies in Pediatric Lupus Nephritis using Mycophenolic Acid (PI: H. Brunner, Cincinnati Children’s Hospital), ongoing

Cincinnati Children’s Hospital Medical Center Translational Research Initiative grant: Pharmacogenetics of IMPDH in Kidney Transplant Patients (PI: A. Vinks, Cincinnati Children’s Hospital), ongoing

Neurosurgery

Kerry R. Crone, MD

513-636-4726

kerry.crone@cchmc.org

Kerry R. Crone, MD

Professor, UC Department of Surgery

Phone: 513-636-4726

Email: kerry.crone@cchmc.org

Show All

Specialties

Clinical Interests

Minimal access surgery; including endoscopic surgery; chiari malformations; brain tumors; design and implementation of patient safety initiatives and clinical outcomes studies

Research Interests

Chiari malformations; brain tumors; telemedicine

Biography

Dr. Kerry Crone is a Professor of Neurosurgery and Pediatrics at Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine. He has been director of the Division of Pediatric Neurosurgery at Cincinnati Children’s Hospital Medial Center since July 1999.

Dr. Crone's specialty interests include minimal access surgery and its applications for children with brain tumors, hydrocephalus and complex cysts within the brain. He has lectured extensively and taught other neurosurgeons these techniques at national and international meetings and courses and written numerous scholarly articles about the use of endoscopy and other tools to allow for these minimally invasive operations and has even been instrumental in designing some of the tools used by neurosurgeons around the world in visualizing and navigating during these operations.

He also has developed a very large and well renowned practice specializing in pediatric patients from infancy to young adulthood with Chiari malformations, offering not only the latest in imaging and surgical approaches, but expertise based on extensive research in this field.

The design of our neurosurgical operative suite, which was the first of its kind in the world, and incorporates intraoperative MRI with specially designed pediatric operating beds and computer guided navigation instruments to allow for maximal safety during resection of brain tumors and other complex operations of the brain and spine, was guided by his experience and expertise.

Education and Training

MD: University of Cincinnati, Cincinnati, OH, 1978

Residency: Neurosurgery, Bowman-Gray School of Medicine, Winston-Salem, NC

Fellowship: Pediatric Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada, 1986

Publications

View PubMed Publications

Phillips CL, Miles L, Jones BV, Sutton M, Crone K, Fouladi M. Medulloblastoma with melanotic differentiation: case report and review of the literature. J Neurooncol. 2010 Oct 16.

Stevenson CB, Leach JL, Gupta A, Crone KR. Cystic degeneration of the cerebellar tonsils in pediatric patients with Chiari Type I malformation. J Neurosurg Pediatr. 2009 Dec;4(6):557-63.

Air E, Ghomri YM, Tyagi R, Grande AW, Crone K, and Mangano FT. Management of Vagal Nerve Stimulator Infections. Do they need to be removed? J Neurosurg Pediatr. 2009; 3(1): 73-78.

Yuan W, Holland S, Jones BV, Crone K, and Mangano FT. Characterization of Abnormal Diffusion Properties of Supratentorial Brain Tumors: A Preliminary DTI Study. J Neurosurg Pediatr. 2009; 1(4): 263-269.

Agabegi SS, Antekeier DP, Crawford AH, Crone KR. Postlaminectomy kyphosis in an achondroplastic adolescent treated for spinal stenosis. Orthopedics. 2008 Feb;31(2):168.

Neely JC 2nd, Jones BV, Crone KR. Spontaneous extracranial decompression of epidural hematoma. Pediatr Radiol. 2008; 38(3):316-8.

Levine NB, Miller MN, Crone KR. Endoscopic resection of colloid cysts: Indications, technique, and results during a 13-year period. Minim Invas Neurosurg. 2007; 50:313-317.

Francesco T. Mangano, DO, FACOS
Director, Division of Pediatric Neurosurgery

513-636-4726

francesco.mangano@cchmc.org

High Res

Francesco T. Mangano, DO, FACOS

Director, Division of Pediatric Neurosurgery

Co-Director, Epilepsy Surgery Program

Associate Professor, Division of Pediatric Surgery

Phone: 513-636-4726

Fax: 513-636-2808

Email: francesco.mangano@cchmc.org

Show All

Specialties

Clinical Interests

Epilepsy surgery; spinal deformity; hydrocephalus; oncology

Research Interests

Epilepsy; spine and spinal cord tumors; spinal deformity; hydrocephalus; cerebrovascular disease

Biography

Francesco Mangano, MD, joined the Division of Pediatric Neurosurgery at Cincinnati Children's in July 2005, as an associate professor of neurosurgery.

A graduate of the Philadelphia College of Osteopathic Medicine, Dr. Mangano completed his neurosurgical residency at Long Island Jewish Medical Center in 2004 followed by a fellowship in pediatric neurosurgery at St. Louis Children's Hospital in St. Louis, Missouri.

Since joining the faculty of the division of pediatric neurosurgery at this Cincinnati Children's Hospital Medical Center, he has been instrumental in developing our nationally renowned Pediatric Epilepsy Program and is Director of the Pediatric Epilepsy Surgery Program. This program has already given many children a chance to experience a whole new life with marked reduction in the frequency of their debilitating seizures. After extensive evaluation and state of the art imaging and monitoring of the seizures, surgical intervention in many cases can then be exactly targeted to the source of the seizures. An extensive array of surgical techniques may be offered these patients, which ranges from implantation of a vagal nerve stimulator to resection of one whole side of the brain.

In addition, he is a co-principal investigator for an NIH-funded multi-institutional research study investigating advanced MRI imaging techniques in children with congenital hydrocephalus. This is only one of his numerous active research projects which have resulted in numerous publications, book chapters and national and international presentations in the fields of epilepsy, diffusion tensor imaging (MRI) of hydrocephalus, traumatic brain injury, and vascular and neoplastic brain lesions. He also has expertise in complex disorders of the spine and spinal cord, including spinal cord tumors, and craniocervical junction.

Education and Training

DO: Philadelphia College of Osteopathic Medicine (PCOM), Philadelphia, PA.

Residency: NYCOM-Long Island, Jewish Medical Center / North Shore University Health System, New Hyde Park, NY.

Fellowship: Washington University School of Medicine-St. Louis Children's Hospital, St. Louis, MO.

Publications

View PubMed Publications

Kadar AA, Hearst MJ, Collins MH, Mangano FT, Samy RN. Ewing's Sarcoma of the Petrous Temporal Bone: Case Report and Literature Review. Skull Base. 2010 May;20(3):213-7.

Seo JH, Holland K, Rose D, Rozhkov L, Fujiwara H, Byars A, Arthur T, DeGrauw T, Leach JL, Gelfand MJ, Miles L, Mangano FT, Horn P, Lee KH. Multimodality imaging in the surgical treatment of children with nonlesional epilepsy. Neurology. 2011 Jan 4;76(1):41-8.

Yuan W, Deren KE, McAllister JP 2nd, Holland SK, Lindquist DM, Cancelliere A, Mason M, Shereen A, Hertzler DA, Altaye M, Mangano FT. Diffusion tensor imaging correlates with cytopathology in a rat model of neonatal hydrocephalus. Cerebrospinal Fluid Res. 2010 Nov 5;7:19.

Hertzler DA 2nd, DePowell JJ, Stevenson CB, Mangano FT. Tethered cord syndrome: a review of the literature from embryology to adult presentation. Neurosurg Focus. 2010 Jul;29(1):E1. Review.

Patel NN, Mangano FT, Klimo P Jr. Indirect revascularization techniques for treating moyamoya disease. Neurosurg Clin N Am. 2010 Jul;21(3):553-63. Review.

Air EL, Yuan W, Holland SK, Jones BV, Bierbrauer K, Altaye M, Mangano FT. Longitudinal comparison of pre- and postoperative diffusion tensor imaging parameters in young children with hydrocephalus. J Neurosurg Pediatr. 2010 Apr;5(4):385-91.

Desai R, Stevenson CB, Crawford AH, Durrani AA, Mangano FT. C-1 lateral mass screw fixation in children with atlantoaxial instability: case series and technical report. J Spinal Disord Tech. 2010 Oct;23(7):474-9.

Xiang J, Wang Y, Chen Y, Liu Y, Kotecha R, Huo X, Rose DF, Fujiwara H, Hemasilpin N, Lee K, Mangano FT, Jones B, DeGrauw T. Noninvasive localization of epileptogenic zones with ictal high-frequency neuromagnetic signals. J Neurosurg Pediatr. 2010 Jan;5(1):113-22.

Yuan W, Mangano FT, Air EL, Holland SK, Jones BV, Altaye M, Bierbrauer K. Anisotropic diffusion properties in infants with hydrocephalus: a diffusion tensor imaging study. AJNR Am J Neuroradiol. 2009 Oct;30(9):1792-8.

Xiang J, Liu Y, Wang Y, Kirtman EG, Kotecha R, Chen Y, Huo X, Fujiwara H, Hemasilpin N, Lee K, Mangano FT, Leach J, Jones B, DeGrauw T, Rose D. Frequency and spatial characteristics of high-frequency neuromagnetic signals in childhood epilepsy. Epileptic Disord. 2009 Jun;11(2):113-25.

Grants

Longitudinal DTI study in children treated for congenital hydrocephalus. Co-Principal Investigator. National Institutes of Health. 2009-2013. #R01-01 NS066932.

Rodent Models of Congenital Hydrocephalus. Co-Principal Investigator. Supplement to McLaurin Fund. Jul 2010 – Jun 2013.

Change the Outcome Fund. Co-investigator. Cincinnati Children’s Hospital Medical Center. Aug 2009 – Jun 2011.

Quick Links

Quick Links

Quick Links

Quick Links

Quick Links

Colorectal Center

E-mail this page

Colorectal Center

Meet the Team

Colorectal Surgery

Andrea Bischoff, MD

Specialties

Biography

Education and Training

Publications

Jason S. Frischer, MD

Specialties

Biography

Education and Training

Publications

Michael A. Helmrath, MD, MS

Biography

Education and Training

Publications

Grants

Belinda Hsi Dickie, MD, PhD

Specialties

Biography

Education and Training

Publications

Marc A. Levitt, MD

Specialties

Biography

Education and Training

Publications

Ebony Moorefield, APRN

Alberto Pena, MD

Specialties

Biography

Education and Training

Publications

Daniel von Allmen, MD

Specialties

Clinical Interests

Research Interests

Biography

Education and Training

Publications

Colorectal Staff

Giulia Brisighelli, MD

Education and Training

Kimberly E. Cain, RN, MSN, CNP, CWOCN

Specialties

Education and Training

Inbal Samuk, MD

Specialties

Biography

Education and Training

Publications

Anesthesia

Lori Aronson, MD

Specialties

Clinical Interests

Biography

Education and Training

Publications

Book Chapters

Anne Boat, MD

Specialties

Education and Training

Nancy S. Hagerman, MD

Education and Training

Publications

Mario Patino, MD

Specialties

Clinical Interests

Research Interest

Biography

Education and Training

James P. Spaeth, MD