Diagnostic Center for Heritable Immunodeficiencies

The Diagnostic Center for Heritable Immunodeficiencies (DCHI) at Cincinnati Children's Hospital Medical Center comprises three services working cooperatively to offer a comprehensive approach to the diagnosis and management of patients with severe immune deficiencies:

• Molecular Genetics Laboratory, offering high-quality molecular testing and sophisticated interpretation of results
• Diagnostic Immunology Laboratory, offering correlated functional assays for a wide range of immune diseases
• Clinical Services: Immunodeficiencies and Histiocytosis Program, offering experienced medical management including one of the country’s largest stem cell transplantation programs

We are recognized by both the Federation of Clinical Immunology Societies (FOCIS) and the Jeffrey Modell Foundation as a Center of Excellence.

DCHI News

• Clinical testing for ITK deficiency is now available.  ITK testing is appropriate for any female patient with EBV-associated lymphoproliferative disease and for male patients with normal SH2D1A and BIRC4 analyses.
• Clinical testing for SBDS (Shwachman Diamond syndrome) is now available.  
• Need help in determining the most efficient sequence of testing for your HLH patients?  Please see our new FHL Testing Algorithm 

We provide the highest quality, most comprehensive clinical testing available to help detect, diagnose and treat pediatric oncologic, hematologic and immunologic disorders.