Clinical Interests

Neonatology; congenital diaphragmatic hernia; neonatal infection

Research Interests

Innate immune systems; surfactant protein D; neutrophil function in Cystic Fibrosis

King BA, Boyd JT, Kingma PS. Pulmonary maturational arrest and death in a patient with pulmonary interstitial glycogenosis. Pediatr Pulmonol. 2011 May 26.

Lee TC, Lim FY, Keswani SG, Frischer JS, Haberman B, Kingma PS, Habli M, Jaekle RK, Sharp G, Kline-Fath B, Rubio EI, Calvo M, Guimaraes C, Crombleholme TM. Late gestation fetal magnetic resonance imaging-derived total lung volume predicts postnatal survival and need for extracorporeal membrane oxygenation support in isolated congenital diaphragmatic hernia. J Pediatr Surg. 2011 Jun;46(6):1165-71.

King BA, Kingma PS. Surfactant Protein D Deficiency Increases Lung Injury during Endotoxemia. Am J Respir Cell Mol Biol. 2011 May;44(5):709-15.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer J, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

White M, Kingma PS, Tecle T, Kacak N, Linders B, Heuser J, Crouch E, Hartshorn K. Multimerization of surfactant protein D, but not its collagen domain, is required for antiviral or opsonic activities related to influenza A virus. J Immunol.  2008 Dec 1;181(11):7936-43.

Kingma PS, Zhang L, Ikegami M, Hartshorn K, McCormack FX, Whitsett JA. Correction of pulmonary abnormalities in Sftpd-/- mice requires the collagenous domain of surfactant protein D. J Biol Chem. 2006 Aug 25;281(34):24496-505.

Kingma PS, Whitsett JA. In defense of the lung: surfactant protein A and surfactant protein D. Curr Opin Pharmacol. 2006 Jun;6(3):277-83.

BA: University of Wisconsin-Milwaukee; University of Wisconsin-Madison.

MD: Medical College of Wisconsin, Milwaukee, Wisconsin, 1983.

Internship: Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, Washington, 1983-1984.

Residency: Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, Washington, 1984-1987.

Fellowship: Maternal-Fetal Medicine, Madigan Army Medical Center, Tacoma, Washington, 1989-1991.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Habli M, Cnota J, Michelfelder E, Salisbury S, Schnell B, Polzin W, Lim FY, Crombleholme TM. The relationship between amniotic fluid levels of brain-type natriuretic peptide and recipient cardiomyopathy in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2010 Oct;203(4):404.e1-7

Morris LM, Lim FY, Livingston JC, Polzin WJ, Crombleholme TM. High-risk fetal congenital pulmonary airway malformations have a variable response to steroids. J Pediatr Surg. 2009 Jan;44(1):60-5.

Michelfelder E, Polzin W, Hirsch R. Hypoplastic left heart syndrome with intact atrial septum: Utilization of a hybrid catheterization facility for cesarean section delivery and prompt neonatal intervention. Catheter Cardiovasc Interv. 2008 Dec 1;72(7):983-7.

Habli M, Michelfelder E, Livingston J, Harmon J, Lim FY, Polzin W, Crombleholme T. Acute effects of selective fetoscopic laser photocoagulation on recipient cardiac function in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2008 Oct;199(4):412.e1-6.

Michelfelder E, Gottliebson W, Border W, Kinsel M, Polzin W, Livingston J, Khoury P, Crombleholme T. Early manifestations and spectrum of recipient twin cardiomyopathy in twin-twin transfusion syndrome: relation to Quintero stage. Ultrasound Obstet Gynecol. 2007 Dec;30(7):965-71.

Livingston JC, Lim FY, Polzin W, Mason J, Crombleholme TM. Intrafetal radiofrequency ablation for twin reversed arterial perfusion (TRAP): a single-center experience. Am J Obstet Gynecol. 2007 Oct;197(4):399.e1-3.

Crombleholme TM, Shera D, Lee H, Johnson M, D'Alton M, Porter F, Chyu J, Silver R, Abuhamad A, Saade G, Shields L, Kauffman D, Stone J, Albanese CT, Bahado-Singh R, Ball RH, Bilaniuk L, Coleman B, Farmer D, Feldstein V, Harrison MR, Hedrick H, Livingston J, Lorenz RP, Miller DA, Norton ME, Polzin WJ, Robinson JN, Rychik J, Sandberg PL, Seri I, Simon E, Simpson LL, Yedigarova L, Wilson RD, Young B. A prospective, randomized, multicenter trial of amnioreduction vs selective fetoscopic laser photocoagulation for the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol. 2007 Oct;197(4):396.e1-9.

Coppage KH, Polzin WJ. Severe Preeclampsia and Delivery Outcomes: Is Immediate Cesarean Delivery Beneficial? Am J Obstet Gynecol. 2002;186:921-3.

Surgical treatment of fetal and newborn diseases; open and minimally invasive fetal surgery; congenital lung and airway disease; congenital esophageal disease; sacrococcygeal teratoma; conjoined twins and neonatal surgery; mechanisms of long-term immunologic tolerance to prenatally transplanted stem cells; developmental hematology, pluripotent stem cell biology; fetal gene therapy

MD: University of Illinois College of Medicine, Chicago, IL, 1991.

Residency: General Surgery, University of Iowa Hospital and Clinics; Pediatric Surgery, The Children’s Hospital of Philadelphia.

Fellowship: Fetal Surgery Research, Children’s Hospital of Philadelphia; Fetal Surgery, Children’s Hospital of Philadelphia.

Certification: Surgery 1998, 2011; Pediatric Surgery, 2006. 

Mulla ZD, Nuwayhid BS, Garcia KM, Flood-Shaffer K, Van Hook JW, Hampton RM. Risk factors for a prolonged length of stay in women hospitalized for preeclampsia in Texas. Hypertens Pregnancy. 2010 Jan;29(1):54-68.

Vrabec JT, Isaacson B, Van Hook JW. Bell's palsy and pregnancy. Otolaryngol Head Neck Surg. 2007 Dec;137(6):858-61. 
 
Kauffman RP, Castracane VD, Peghee D, Baker TE, Van Hook JW. Detection of gestational diabetes mellitus by homeostatic indices of insulin sensitivity: a preliminary study. Am J Obstet Gynecol. 2006 Jun;194(6):1576-82

Tiwari R, Hicks K, Naqvi M, Biskinis E, Nirgiotis J, Van Hook J, Suffield R. Prenatal diagnosis of a neonate with fetus in fetu. J Perinatol. 2006;26:366-367. 

Book Chapters

Van Hook JW. Substance Abuse and Addiction. In Evans A (ed) Manual of Obstetrics. 7th ed. Lippincott, Williams and Wilkins, 2007.

Van Hook JW. Trauma in Pregnancy for Critical Care Obstetrics. In Belfort M, Saade G, Foley M, Phelan J, Dildy G (eds) Critical Care Obstetrics. 5th ed. Malden, Massachusetts: Blackwell Science, 2008.

Modification of the Wigglesworth model of Intrauterine growth restriction in mice as the animal model; invitro assessment of Insulin like growth factors and adenoviral associated gene expression of insulin like growth factor-I in a rat trophoblast cell line (RCHO-1)

Pizarro D, Habli M, Grier M, Bombrys A, Sibai B, Livingston J. Higher maternal doses of methadone does not increase neonatal abstinence syndrome. J Subst Abuse Treat. 2011 Jan 19.

Keswani SG, Le LD, Morris LM, Lim FY, Katz AB, Ghobril N, Habli M, Frischer JS, Crombleholme TM. Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy. J Pediatr Surg. 2011 Jan;46(1):33-8.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Habli M, Cnota J, Michelfelder E, Salisbury S, Schnell B, Polzin W, Lim FY, Crombleholme TM. The relationship between amniotic fluid levels of brain-type natriuretic peptide and recipient cardiomyopathy in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2010 Oct;203(4):404.e1-7.

Habli M, Bombrys A, Lewis D, Lim FY, Polzin W, Maxwell R, Crombleholme T. Incidence of complications in twin-twin transfusion syndrome after selective fetoscopic laser photocoagulation: a single-center experience. Am J Obstet Gynecol. 2009 Oct;201(4):417.e1-7.

Habli M, Eftekhari N, Wiebracht E, Bombrys A, Khabbaz M, How H, Sibai B. Long-term maternal and subsequent pregnancy outcomes 5 years after hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome. Am J Obstet Gynecol. 2009 Oct;201(4):385.e1-5.

Katz AB, Keswani SG, Habli M, Lim FY, Zoltick PW, Midrio P, Kozin ED, Herlyn M, Crombleholme TM. Placental gene transfer: transgene screening in mice for trophic effects on the placenta. Am J Obstet Gynecol. 2009 Nov;201(5):499.e1-8

Habli M, Lim FY, Crombleholme T. Twin-to-twin transfusion syndrome: a comprehensive update. Clin Perinatol. 2009 Jun;36(2):391-416, x. Review.

Bombrys AE, Barton JR, Habli M, Sibai BM. Expectant management of severe preeclampsia at 27(0/7) to 33(6/7) weeks' gestation: maternal and perinatal outcomes according to gestational age by weeks at onset of expectant management. Am J Perinatol. 2009 Jun;26(6):441-6.

Lubow JM, How HY, Habli M, Maxwell R, Sibai BM. Indications for delivery and short-term neonatal outcomes in late preterm as compared with term births. Am J Obstet Gynecol. 2009 May;200(5):e30-3.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Morris LM, Lim FY, Elluru RG, Hopkin RJ, Jaekle RK, Polzin WJ, Crombleholme TM. Severe micrognathia: indications for EXIT-to-Airway. Fetal Diagn Ther. 2009;26(3):162-6.

Lewis DF, Robichaux AG, Jaekle RK, Salas A, Canzoneri BJ, Horton K, Jaekle L, Stedman C. Expectant management of preterm premature rupture of membranes and nonvertex presentation: what are the risks? Am J Obstet Gynecol. 2007 196:566.e1-5;discussion 566.e5-6. 

Jaekle RK, Lutz PD, Rosenn B, Siddiqi TA, Myatt L. Nitric oxide metabolites and preterm pregnancy complications. Am J Obstet Gynecol. 1994 Oct;171(4):1115-9.

Combs CA, Jaekle RK, Rosenn B, Pope M, Miodovnik M, Siddiqi TA. Sonographic estimation of fetal weight based on a model of fetal volume. Obstet Gynecol. 1993 Sep;82(3):365-70. Review.

Gene therapy applications; bone marrow contribution to tissue repair; fetal diagnosis and treatment

Keswani SG, Le LD, Morris LM, Lim FY, Katz AB, Ghobril N, Habli M, Frischer JS, Crombleholme TM. Submucosal gland development in the human fetal trachea xenograft model: implications for fetal gene therapy. J Pediatr Surg. 2011 Jan;46(1):33-8.

Bischoff A, Gupta A, D'Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn's disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.

Morris LM, Klanke CA, Lang SA, Pokall S, Maldonado AR, Vuletin JF, Alaee D, Keswani SG, Lim FY, Crombleholme TM. Characterization of endothelial progenitor cells mobilization following cutaneous wounding. Wound Repair Regen. 2010 Jul-Aug;18(4):383-90.

Katz AB, Keswani SG, Habli M, Lim FY, Zoltick PW, Midrio P, Kozin ED, Herlyn M, Crombleholme TM. Placental gene transfer: transgene screening in mice for trophic effects on the placenta. Am J Obstet Gynecol. 2009 Nov;201(5):499.e1-8

Vachharajani AJ, Rao R, Keswani S, Mathur AM. Outcomes of exomphalos: an institutional experience. Pediatr Surg Int. 2009 Feb;25(2):139-44.

Khan AR, Morris LM, Keswani SG, Khan IR, Le L, Lee WC, Hunt JP. Tuberculous peritonitis: a surgical dilemma. South Med J. 2009 Jan;102(1):94-5.

Bucher BT, Seigel J, Rosenblum E, Nesslein C, Keswani SG, Foglia R, Dillon P, Warner BW and Keller MS. A pediatric ambulatory wound service (PAWS): A novel approach in wound management. J Ped Surg 2009. 

Gordon A, Kozin ED, Keswani SG, Vaikunth SS, Katz AB, Zoltick PW, Favata M, Radu AP, Soslowsky LJ, Herlyn M, Crombleholme TM. Permissive environment in postnatal wounds induced by adenoviral-mediated overexpression of the anti-inflammatory cytokine interleukin-10 prevents scar formation. Wound Repair Regen. 2008 Jan-Feb;16(1):70-9.

Parvadia JK, Keswani SG, Vaikunth S, Maldonado AR, Marwan A, Stehr W, Erwin C, Uzvolgyi E, Warner BW, Yamano S, Taichman N, Crombleholme TM. Role of VEGF in small bowel adaptation after resection: the adaptive response is angiogenesis dependent. Am J Physiol Gastrointest Liver Physiol. 2007 Sep;293(3):G591-8.

Keswani SG, Javazon EH, Badillo AT, Crombleholme TM, Zoltick PW, Radu AP, Kozin ED, Beggs K, Malik AA, Flake AW. Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cells. Wound Repair Regen. 2007 May-Jun;15(3):350-9.

Clinical Interests

Fetal cardiology including fetal echocardiography

Research Interests

Impact of insulin sensitivity on left ventricular mass in healthy teens; blood pressure in offspring of preeclamptic mothers; fetal programming of cardiovascular outcomes; multicenter trials in pediatric heart disease

BS: Molecular and Cellular Biology, University of Arizona, Tucson, Arizona, 1991

MD: Tulane University School of Medicine, New Orleans, Louisiana, 1995

Residency: University of Arizona Health Sciences Center, Tucson, Arizona, 1998

Fellowship: Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, 2001

MS: Clinical Epidemiology and Health Services Research, Wake Forest University School of Medicine, Winston-Salem, North Carolina, 2005

Divanović A, Hor K, Cnota J, Hirsch R, Kinsel-Ziter M, Michelfelder E. Prediction and perinatal management of severely restrictive atrial septum in fetuses with critical left heart obstruction: Clinical experience using pulmonary venous Doppler analysis. J Thorac Cardiovasc Surg. 2010 Dec 2.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Habli M, Cnota J, Michelfelder E, Salisbury S, Schnell B, Polzin W, Lim FY, Crombleholme TM. The relationship between amniotic fluid levels of brain-type natriuretic peptide and recipient cardiomyopathy in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2010 Oct;203(4):404.e1-7.

Hambrook JT, Kimball TR, Khoury P, Cnota J. Disparities exist in the emergency department evaluation of pediatric chest pain. Congenit Heart Dis. 2010 May-Jun;5(3):285-91.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer J, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

Hor KN, Gottliebson WM, Carson C, Wash E, Cnota J, Fleck R, Wansapura J, Klimeczek P, Al-Khalidi HR, Chung ES, Benson DW, Mazur W. Comparison of magnetic resonance feature tracking for strain calculation with harmonic phase imaging analysis. JACC Cardiovasc Imaging. 2010 Feb;3(2):144-51.

Land MH, Rouster-Stevens K, Woods CR, Cannon ML, Cnota J, Shetty AK. Lactobacillus sepsis associated with probiotic therapy. Pediatrics. 2005 Jan;115(1):178-81.

Grace BE, Cnota JF, Hines MH, Payne RM, Ririe DO. Traumatic Coronary Artery Fistula in a Child. Circulation 2005;1 II :e272-e273.

Clinical Interests

Echocardiography

Research Interests

Dyssynchrony; quality improvement

BS: Bucknell University, Lewisburg, PA, 1986.

MD: Penn State University College of Medicine, Hershey, Pennsylvania, 1990.

Residency: St. Christopher's Hospital for Children, Temple University School of Medicine, Philadelphia, Pennsylvania, 1990-1993.

Fellowship: C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, Michigan, 1993-1996.

Certification: Pediatrics 1991, Pediatric Cardiology 1998.

Divanovic A, Hor K, Cnota JF, Hirsch R, Kinsel-Ziter M, Michelfelder EC. Prediction and perinatal management of severely restrictive atrial septum in fetuses with critical left heart obstruction: clinical experience using pulmonary venous Doppler analysis. Journal of Thoracic and Cardiovascular Surgery. [in press]

Divanović A, Hor K, Cnota J, Hirsch R, Kinsel-Ziter M, Michelfelder E. Prediction and perinatal management of severely restrictive atrial septum in fetuses with critical left heart obstruction: Clinical experience using pulmonary venous Doppler analysis. J Thorac Cardiovasc Surg. 2010 Dec 2.

Crombleholme TM, Lim FY, Habli M, Polzin W, Jaekle R, Michelfelder E, Cnota J, Liu C, Kim MO. Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation. Am J Obstet Gynecol. 2010 Oct;203(4):397.e1-9.

Habli M, Cnota J, Michelfelder E, Salisbury S, Schnell B, Polzin W, Lim FY, Crombleholme TM. The relationship between amniotic fluid levels of brain-type natriuretic peptide and recipient cardiomyopathy in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2010 Oct;203(4):404.e1-7.

Eghtesady P, Michelfelder EC, Knilans TK, Witte DP, Manning PB, Crombleholme TM. Fetal surgical management of congenital heart block in a hydropic fetus: Lessons learned from a clinical experience. J Thorac Cardiovasc Surg. 2011 Mar;141(3):835-7.

Boat A, Mahmoud M, Michelfelder EC, Lin E, Ngamprasertwong P, Schnell B, Kurth CD, Crombleholme TM, Sadhasivam S. Supplementing desflurane with intravenous anesthesia reduces fetal cardiac dysfunction during open fetal surgery. Paediatr Anaesth. 2010 Aug;20(8):748-56.

Hinton RB, Michelfelder EC, Marino BS, Bove KE, Ware SM. A fetus with hypertrophic cardiomyopathy, restrictive, and single-ventricle physiology, and a beta-myosin heavy chain mutation. J Pediatr. 2010 Jul;157(1):164-6. Epub 2010 Apr 14.

Kinsel-Ziter ML, Cnota JF, Crombleholme TM, Michelfelder EC. Twin-reversed arterial perfusion sequence: pre- and postoperative cardiovascular findings in the 'pump' twin. Ultrasound Obstet Gynecol. 2009 Nov;34(5):550-5.

Michelfelder E, Polzin W, Hirsch R. Hypoplastic left heart syndrome with intact atrial septum: Utilization of a hybrid catheterization facility for cesarean section delivery and prompt neonatal intervention. Catheter Cardiovasc Interv. 2008 Dec 1;72(7):983-7.

Habli M, Michelfelder E, Livingston J, Harmon J, Lim FY, Polzin W, Crombleholme T. Acute effects of selective fetoscopic laser photocoagulation on recipient cardiac function in twin-twin transfusion syndrome. Am J Obstet Gynecol. 2008 Oct;199(4):412.e1-6.

Shah AD, Border WL, Crombleholme TM, Michelfelder EC. Initial fetal cardiovascular profile score predicts recipient twin outcome in twin-twin transfusion syndrome. J Am Soc Echocardiogr. 2008 Oct;21(10):1105-8.

Clinical Interests

Fetal malformations of the brain and spinal cord; spina bifida; tethered cord; head injury

Research Interests

Head injury; biomedical informatics 
 

MD: Medical University of South Carolina, Charleston, South Carolina, 1980-1984

Residency: Neurosurgery, Emory University, Atlanta, Georgia, 1985-1989

Fellowship: Pediatric Neurosurgery, The Children's Memorial Hospital, Chicago, Illinois

Clinical Interests

Brain tumors; spasticity; Chiari malformations; fetal surgery; neurovascular disorders; minimal access surgery

Research Interests

Neuro-oncology; epilepsy; spasticity

Hertzler II DA, DePowell JJ, Stevenson CB, Mangano FT. Tethered cord syndrome: a review of the literature from embryology to adult presentation. Neurosurgical Focus. 2010;29(1):E1.

Stevenson CB, Desai RR, Crawford AH, Durrani AA, Mangano FT. C-1 lateral mass screw fixation in children with atlantoaxial instability: case series and technical report. Journal of Spinal Disorders and Techniques. 2010 Oct;23(7):474-9.

Reig AS, Stevenson CB, Tulipan NT.  CT-based, fiducial-free frameless stereotaxy for difficult ventriculoperitoneal shunt insertion: experience in 26 consecutive patients. Stereotactic and Functional Neurosurgery. 2010; 88(2):75-80.

Stevenson CB, Leach JL, Gupta A, Crone KR.  Cystic degeneration of the cerebellar tonsils in pediatric patients with Chiari I malformation. J Neurosurg Ped. 2009; 4(6):557-63.

McMillan KM, Ehtesham M, Stevenson CB, Edgeworth ML, Thompson RC, Price RR.  T2 detection of tumor invasion within segmented components of glioblastoma multiforme. J Mag Reson Imag. 2009; 29(2):251-7.

Ehtesham M, Mapara KY, Stevenson CB, Thompson RC. CXCR4 mediates the proliferation of glioblastoma progenitor cells. Cancer Letters. 2009; 274(2):305-12.

Ehtesham M, Stevenson CB, Thompson RC.  Preferential expression of chemokine receptor CXCR4 by highly malignant human gliomas and its association with poor patient survival. Neurosurgery. 2008; 63(4):E820.

Stevenson CB, Ehtesham M, McMillan KM, Valadez JG, Edgeworth ML, Price RR, Abel TW, Mapara KY, Thompson RC.  CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peri-tumoral T2-weighted MRI signal abnormalities. Neurosurgery. 2008;63(3):560-9.

Johnson MD, Stevenson CB, Thompson RC, Atkinson J, Boyer P.  31-year-old woman with hemiparesis . Brain Pathology. 2007;17(2):255-7.

Book Chapters

Stevenson CB, Crone KR. Head injury. In Operative Pediatric Surgery Ziegler MM, Azizkhan RG, Weber T, von Allmen D (eds.). 2nd Edition. Mcgraw-Hill: New York ,NY, 2012. (In press).

Fetal imaging; body imaging; ultrasound

Guimaraes CV, Kline-Fath BM, Linam LE, Calvo Garcia MA, Rubio EI, Lim FY. MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP). Pediatr Radiol. 2011 Jun;41(6):694-701.

Calvo-Garcia MA, Kline-Fath BM, Levitt MA, Lim FY, Linam LE, Patel MN, Kraus S, Crombleholme TM, Peña A. Fetal MRI clues to diagnose cloacal malformations. Pediatr Radiol. 2011 Mar 16.

Yazici Z, Kline-Fath BM, Yazici B, Rubio EI, Calvo-Garcia MA, Linam LE. Congenital dacryocystocele: prenatal MRI findings. Pediatr Radiol. 2010 Dec;40(12):1868-73.

Calvo-Garcia MA, Kline-Fath BM, Jones BB, Care MM, Koch BL. Brain malformations associated with epignathus: a clue for the correct prenatal diagnosis. Pediatr Radiol. 2009 Dec;39(12):1369-72.

Guimaraes CV, Linam LE, Line-Fath BM, Donnelly LF, Calvo-Garcia MA, Rubio EI, Livingston JC, Hopkin RJ, Peach E, Lim FY, Crombleholme TM. Prenatal MRI findings of fetuses with congenital high airway obstruction sequence. Korean Journal of Radiology. 2009;10(2):129-34.

Calvo-Garcia MA, Kline-Fath BM, Jones BB, Caré MM, Koch BL. Brain malformations associated with epignathus: a clue for the correct prenatal diagnosis. Pediatric Radiol. 2009:39:1369-72.

Calvo-Garcia MA, Campbell KM, O’Hara SM, Khoury P, Mitsnefes MM, Strife CF. Acquired renal cysts after pediatric liver transplantation: Association with cyclosporine and renal dysfunction. Pediatr Transplantation. 2008:12:666-71.

Kline-Fath BM, Calvo MA, O'Hara SM. Water imaging (hydrography) in the fetus, the value of a heavily T2 weighted sequence. Pediatr Radiol. 2007;37:133-40.

Kline-Fath BM, Calvo-Garcia MA, O'Hara, SM, Crombleholme TM. Twin-twin transfusion syndrome: cerebral ischemia is not the only fetal MR finding. Pediatr Radiol. 2007;37:47-56.

Fetal imaging; pediatric neuroimaging

Guimaraes CV, Kline-Fath BM, Linam LE, Calvo Garcia MA, Rubio EI, Lim FY. MRI findings in multifetal pregnancies complicated by twin reversed arterial perfusion sequence (TRAP). Pediatr Radiol. 2010 Dec 22.

Yazici Z, Kline-Fath BM, Yazici B, Rubio EI, Calvo-Garcia MA, Linam LE. Congenital dacryocystocele: prenatal MRI findings. Pediatr Radiol. 2010 Dec;40(12):1868-73.

Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer J, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.

Calvo-Garcia MA, Kline-Fath BM, Jones BB, Care MM, Koch BL. Brain malformations associated with epignathus: a clue for the correct prenatal diagnosis. Pediatr Radiol. 2009 Dec;39(12):1369-72.

Guimaraes CV, Linam LE, Kline-Fath BM, Donnelly LF, Calvo-Garcia MA, Rubio EI, Livingston JC, Hopkin RJ, Peach E, Lim FY, Crombleholme TM. Prenatal MRI findings of fetuses with congenital high airway obstruction sequence. Korean J Radiol. 2009 Mar-Apr;10(2):129-34.

Kline-Fath BM, Calvo-Garcia MA, O'Hara SM, Racadio JM. Water imaging (hydrography) in the fetus: the value of a heavily T2-weighted sequence. Pediatr Radiol. 2007 Feb;37(2):133-40.

Kline-Fath BM, Calvo-Garcia MA, O'Hara SM, Crombleholme TM, Racadio JM. Twin-twin transfusion syndrome: cerebral ischemia is not the only fetal MR imaging finding. Pediatr Radiol. 2007 Jan;37(1):47-56.

Bunch PT, Kline-Fath BM, Imhoff SC, Calvo-Garcia MA, Crombleholme TM, Donnelly LF. Allantoic cyst: a prenatal clue to patent urachus. Pediatr Radiol. 2006 Oct;36(10):1090-5.

O'Hara SM, Frush DP, Babcock DS, Lewis AG, Barr LL, Bukowski TP, Kline-Fath BM, Sheldon CA. Doppler contrast sonography for detecting reduced perfusion in experimental ischemia of prepubertal rabbit testes. Acad Radiol. 1996 Apr;3(4):319-24.

Musculoskeletal and fetal imaging

Minimally invasive laparoscopic-assisted surgery; robotic-assisted surgery; prenatal evaluation; fetal care; UTIs

Traxel EJ, Minevich EA, Noh PH. A review: the application of minimally invasive surgery to pediatric urology: upper urinary tract procedures. Urology. 2010 Jul;76(1):122-33.

Traxel EJ, Minevich EA, Noh PH. A review: the application of minimally invasive surgery to pediatric urology: lower urinary tract reconstructive procedures. Urology. 2010 Jul;76(1):115-20.

Chacko JK, Noh P, Barthold JS, Figueroa TE, Gonzalez R. Latrogenic ureteral injury after laparoscopic cholecystectomy in a 13-year-old boy. J Pediatr Urol. 2008 4(4):322-4.

Neheman A, Noh PH, Piaggio L, González R. The role of laparoscopic surgery for urinary tract reconstruction in infants weighing less than 10 kg: a comparison with open surgery. J Pediatr Urol. 2008 Jun;4(3):192-6.

Wang Y, Barthold J, Figueroa E, González R, Noh PH, Wang M, Manson J. Analysis of five single nucleotide polymorphisms in the ESR1 gene in cryptorchidism. Birth Defects Res A Clin Mol Teratol. 2008 Jun;82(6):482-5.

Neheman A, Noh PH, Brenn R, González R. Laparoscopic urinary tract surgery in infants weighing 6 kg or less: perioperative considerations and comparison to open surgery. J Urol. 2008 Apr;179(4):1534-8.

Piaggio LA, Franc-Guimond J, Noh PH, Wehry M, Figueroa TE, Barthold J, González R. Transperitoneal laparoscopic pyeloplasty for primary repair of ureteropelvic junction obstruction in infants and children: comparison with open surgery. J Urol. 2007 Oct;178(4 Pt 2):1579-83.

Piaggio LA, Noh PH, González R. Reoperative laparoscopic pyeloplasty in children: comparison with open surgery. J Urol. 2007 May;177(5):1878-82.

Davies B, Noh P, Smaldone MC, Ranganathan S, Docimo SG. Paratesticular rhabdomyoma in a young adult: case study and review of the literature. J Pediatr Surg. 2007  42(4):E5-7.

Stein RJ, Matoka DJ, Noh PH, Docimo SG. Spontaneous perforation of congenital bladder diverticulum. Urology. 2005 Oct;66(4):881.

Clinical Interests

Kidney stones; ESWL; genitourinary surgery; clinical trials

Research Interests

Bladder organogenesis; tissue engineering of bladder matrix

MBBS: Nagarjuna University, Guntur, India 1990.

Residency: Albany Medical Center, Albany, NY.

Residency: Albany Medical Center, Albany, NY.

Fellowship: The Hospital For Sick Children, Toronto, ON, Canada.

Certification: American Board of Urology 2001.

Reddy PP, Defoor WR. Ureteroscopy: The standard of care in the management of upper tract urolithiasis in children. Indian J Urol. 2010 Oct;26(4):555-63.

Ivancić V, Defoor W, Jackson E, Alam S, Minevich E, Reddy P, Sheldon C. Progression of renal insufficiency in children and adolescents with neuropathic bladder is not accelerated by lower urinary tract reconstruction. J Urol. 2010 Oct;184(4 Suppl):1768-74.

DeFoor WR, Jackson E, Minevich E, Caillat A, Reddy P, Sheldon C, Asplin J. The risk of recurrent urolithiasis in children is dependent on urinary calcium and citrate. Urology. 2010 Jul;76(1):242-5.

Traxel E, DeFoor W, Reddy P, Sheldon C, Minevich E. Risk factors for urinary tract infection after dextranomer/hyaluronic acid endoscopic injection. J Urol. 2009 Oct;182(4 Suppl):1708-12.

DeFoor WR, Heshmat S, Minevich E, Reddy P, Koyle M, Sheldon C. Long-term outcomes of the neobladder in pediatric continent urinary reconstruction. J Urol. 2009 Jun;181(6):2689-93; discussion 2693-4.

Reddy PP, Borgstein NG, Nijman RJ, Ellsworth PI. Long-term efficacy and safety of tolterodine in children with neurogenic detrusor overactivity. J Pediatr Urol. 2008 Dec;4(6):428-33.

DeFoor W, Clark C, Jackson E, Reddy P, Minevich E, Sheldon C. Risk factors for end stage renal disease in children with posterior urethral valves. J Urol. 2008 Oct;180(4 Suppl):1705-8; discussion 1708.

Heshmat S, DeFoor W, Minevich E, Reddy P, Reeves D, Sheldon C. Use of customized MIC-KEY gastrostomy button for management of MACE stomal complications. Urology. 2008 Nov;72(5):1026-9.

DeFoor W, Minevich E, Jackson E, Reddy P, Clark C, Sheldon C, Asplin J. Urinary metabolic evaluations in solitary and recurrent stone forming children. J Urol. 2008 Jun;179(6):2369-72.

Reddy PP. Recent advances in pediatric uroradiology. Indian J Urol. 2007 Oct;23(4):390-402.