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Areas of research emphasis include:
Vaccine research has included clinical evaluations in all age groups (infants to elderly). Specific vaccines include:
The highlight of the Gamble Program was the licensure of the rotavirus vaccine developed by Gamble investigators Richard Ward and David Bernstein. The vaccine licensed to GlaxoSmithKline and sold as Rotarix is available in more than 100 countries including the United States and Europe.
Antiviral drug research has included evaluation of agents for:
These studies have involved natural and experimental viral challenges.
Over the years, the Gamble Program has been well funded. Current funding includes an NIH VTEU (Vaccine Treatment and Evaluation Unit) contract, an NIH antiviral contract and numerous industrial sponsors.
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