Gamble Program for Clinical Studies

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    Faculty

    A photo of David Bernstein.

    David I. Bernstein, MD, MA
    Director, Gamble Program and VTEU

    513-636-7625

    david.bernstein@cchmc.org

    David I. Bernstein, MD, MA

    Director, Gamble Program and VTEU

    Professor, UC Department of Pediatrics

    Phone: 513-636-7625

    Fax: 513-636-7682

    Email: david.bernstein@cchmc.org

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    Specialties

    Clinical Interests

    Rotavirus; herpes simplex virus; cytomegalovirus; preclinical and clinical evaluations of vaccine; immune response to herpes virus

    Research Interests

    Evaluation of vaccines and antivirals for herpes and rotovirus; development of improved adjuvants and delivery systems for vaccines; treatment and prevention of influenza, norovirus and parvovirus infections

    Biography

    Dr. Bernstein received his MA degree in microbiology and his MD degree from SUNY at Buffalo. His pediatric training was undertaken at USC and the New England Medical Center. This was followed by an ID fellowship at UCLA.

    During his fellowship he became interested in herpes viruses and vaccines. Upon arrival at Cincinnati Children’s Hospital Medical Center he began his work investigating the immunobiology of genital herpes infections. At this time he also became interested in rotavirus and along with his colleague Dr. Richard Ward he investigated the immune responses that provide protection.

    This work led to the development of a live attenuated human rotavirus vaccine initially named 89-12. The 89-12 vaccine was further modified and became the GlaxoSmithKline rotavirus vaccine, Rotarix, currently available in over 100 countries including the USA and EU. Dr. Bernstein is currently evaluating vaccines for CMV, HSV, influenza, avian influenza, RSV, norovirus and parvovirus. Dr. Bernstein has published over 200 manuscripts and book chapters on infectious diseases, vaccines and antivirals. Dr. Bernstein is currently the Albert Sabin Professor of pediatrics and director of the Division of Infectious Diseases at Cincinnati Children’s and directs one of eight NIH funded Vaccine Evaluation Units.

    Education and Training

    MA: Microbiology, State University of New York at Buffalo, Buffalo, NY, 1973.

    MD: State University of New York at Buffalo School of Medicine, Buffalo, NY, 1977.

    Residency: Pediatrics, University of Southern California Medical Center, Los Angeles, CA; Tufts University School of Medicine, Boston, MA.

    Fellowship: Pediatric Infectious Disease, University of California, Los Angeles, CA.

    Certification: American Board of Medical Examiners, 1978; American Board of Pediatrics, 1981; Pediatrics, 1982.

    Publications

    View PubMed Publications

    Grants

    Vaccine and Treatment Evaluation Units (VTEUs): Evaluation of Control Measures Against Diseases Other Than AIDS. Principal Investigator. 2007 - 2014. #NO1-AI-80006.

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    Rebecca C. Brady, MD
    Director, Adult Clinical Services

    513-636-4578

    rebecca.brady@cchmc.org

    No photo available

    Rebecca C. Brady, MD

    Director, Adult Clinical Services

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: rebecca.brady@cchmc.org

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    Specialties

    Clinical Interests

    Adult and pediatric infectious disease

    Research Interests

    Cytomegalovirus and other viral infections 

    Education and Training

    MD: University of Kentucky, Lexington, KY, 1988.

    Residency: Internal Medicine/Pediatrics, University of Louisville, Louisville, KY.

    Fellowships: Pediatric Infectious Diseases, Children's Hospital Medical Center, Cincinnati, Ohio; Adult Infectious Diseases, University of Cincinnati, Cincinnati, OH.

    Certifications: Pediatrics, 1992, recertified 1999; Internal Medicine, 1993; Pediatric Infectious Diseases, 1997; Adult Infectious Diseases, 1997.

    Publications

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    Michelle P. Dickey, MS, CFNP, CPNP, CCRC

    Nurse Practitioner

    Field Service Instructor, Division of Infectious Diseases

    Instructor, UC Department of Pediatrics

    A photo of Robert W. Frenck Jr.

    Robert W. Frenck Jr., MD
    Interim Director, Division of Infectious Diseases

    513-803-3164

    robert.frenck@cchmc.org

    Robert W. Frenck Jr., MD

    Interim Director, Division of Infectious Diseases

    Medical Director, Division of Infectious Diseases

    Professor, UC Department of Pediatrics

    Phone: 513-803-3164

    Fax: 513-636-3959

    Email: robert.frenck@cchmc.org

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    Specialties

    Clinical

    Vaccine research; enteric diseases; travel medicine

    Research

    Enteric diseases; vaccinology

    Biography

    Robert W. Frenck Jr., MD, received his undergraduate degree from the University of California at San Diego in 1977 followed by his doctor of medicine degree from the University of Texas Health Science Center at Houston in 1981. He trained at the National Naval Medical Center in Bethesda, Maryland, completing his pediatric residency in 1984. After three years as a general pediatrician at the US Naval Hospital, Japan, he entered pediatric infectious disease fellowship training at the University of Texas Health Science Center at Houston, which he completed in 1990. Dr. Frenck is board-certified in both pediatrics and infectious diseases.

    Dr. Frenck's research interests include therapeutic and vaccine clinical trials with special interest in enteric diseases. After completing a 25-year career in the Navy, Dr. Frenck joined the UCLA Center for Vaccine Research in 2004 and served until 2006 as director of the Center and a Professor of Pediatrics at UCLA School of Medicine. Dr. Frenck has been active in the American Academy of Pediatrics and currently serves on the Red Book Committee. He is an acknowledged authority in infectious diseases and has authored over 60 articles and book chapters on various aspects of this subject.

    Education and Training

    BA: University of California at San Diego, San Diego, CA, 1977. 

    MD: University of Texas Medical School at Houston, Houston, TX, 1981. 

    Internship and Residency: US Naval Hospital, Bethesda, MD, 1981-1984. 

    Fellowship: Pediatric Infectious Diseases, University of Texas Medical School at Houston, Houston, TX, 1987-1990.

    Publications

    View PubMed Publications

    Xi Jason Jiang, PhD

    Professor, UC Department of Pediatrics

    Phone: 513-636-0119

    Fax: 513-636-7655

    Email: jason.jiang@cchmc.org

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    Specialties

    Infectious diseases; viral gastroenteritis

    Education and Training

    BS: Public Health, Shanghai Medical University, 1978.

    PhD: Baylor College of Medicine, Houston, Texas, 1988.

    Post-doctoral fellow: Baylor College of Medicine, Houston, Texas, 1993.

    Publications

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    A photo of Monica McNeal.

    Monica Malone McNeal, MS
    Associate Director, Laboratory of Specialized Clinical Studies

    513-636-7648

    monica.mcneal@cchmc.org

    Monica Malone McNeal, MS

    Associate Director, Laboratory of Specialized Clinical Studies

    Instructor, UC Department of Pediatrics

    Phone: 513-636-7648

    Fax: 513-636-0950

    Email: monica.mcneal@cchmc.org

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    Specialties

    Clinical Interests

    Vaccine development; rotavirus; influenza and CMV

    Research Interests

    Immunology of rotavirus infection

    Biography

    Monica Malone McNeal, MS, is a virologist in the Division of Infectious Diseases at Cincinnati Children’s Hospital Medical Center. She has more than 23 years of experience in rotavirus research. She has established an adult mouse model that has been used extensively in this facility and labs around the world. Her major expertise is in immunology and vaccine development. Currently she is the Associate Director of the Laboratory for Specialized Clinical Studies. This lab provides support for clinical studies involved in vaccine development. They perform work for several major pharmaceutical companies in addition to supporting other clinical researchers at Cincinnati Children’s.

    Education and Training

    MS: University of Cincinnati, Cincinnati, OH, 1981.

    Publications

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    A photo of Mary Staat.

    Mary Allen Staat, MD, MPH
    Director, International Adoption Center

    513-636-2877

    mary.staat@cchmc.org

    Mary Staat, MD, MPH

    Director, International Adoption Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-2877

    Fax: 513-636-6936

    Email: mary.staat@cchmc.org

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    Specialties

    Clinical Interests

    Helicobacter pylori, rotavirus epidemiology, travel medicine and infectious diseases of international adoptees

    Research Interests

    Epidemiology of enteric infections and surveillance of infectious diseases

    Biography

    Mary Allen Staat, MD, MPH, is director of the International Adoption Center and a member of the Infectious Disease Division at Cincinnati Children's Hospital Medical Center.

    Dr. Staat is a board-certified pediatrician and is also board-certified in Infectious Disease and Preventive Medicine. She is an associate professor of Pediatrics at the University of Cincinnati and a faculty member of the Cincinnati Children's Hospital Research Foundation.

    Education and Training

    MD: University of Kentucky, Lexington, Ky., 1986.

    MPH: Johns Hopkins University, Baltimore, Md., 1991.

    Residency: Pediatrics, Baylor College of Medicine, Houston, Texas, 1986-1989; Preventive Medicine, Johns Hopkins University, Baltimore, Md., 1990-1994.

    Fellowship: Infectious Diseases, Baylor College of Medicine, Houston, Texas, 1989-1990; Epidemiology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rockville, Md., 1990-1993.

    Certification: Pediatrics, 1989; Preventive Medicine, 1996; Pediatric Infectious Diseases, 1999.

    Publications

    View PubMed Publications
    A photo of Richard Ward.

    Richard L. Ward, PhD
    Research Professor

    513-636-7628

    dick.ward@cchmc.org

    Richard L. Ward, PhD

    Research Professor

    Professor, UC Department of Pediatrics

    Phone: 513-636-7628

    Fax: 513-636-0950

    Email: dick.ward@cchmc.org

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    Specialties

    Clinical Interests

    Identification of viral agents of severe gastroenteritis; epidemiology of rotavirus infections and disease worldwide; pathogenesis of rotavirus disease

    Research Interests

    Mechanisms of immune protection against rotavirus; development of rotavirus vaccines

    Biography

    Richard L. Ward, PhD, was born and educated through undergraduate training in Montana. He completed a PhD degree in biochemistry at the Unversity of California, Berkeley in 1969 and conducted post-doctoral research in Munich, Germany and the Roche Institute in Nutley, NJ.

    Dr. Ward held positions at the University of California in Los Angeles and Sandia National Laboratories in Albuquerque, NM, before joining the USEPA in Cincinnati in 1980. After that he joined the Gamble Institute of Medical Research (1981) and Children's Hospital Medical Center (1995). His entire research career has been on viral studies.

    Education and Training

    PhD: Biochemistry, University of California, Berkely, 1969.

    BS: Montana State University, Bozeman, MT, 1965.