Genetic Testing for Hearing Loss

  • Genetic Testing for Hearing Loss

    Customized Interpretation of Test Results

    Genetic factors play a role in up to two thirds of all childhood hearing impairment. Molecular genetic testing assists otologists by providing insight into the etiology of hearing impairment in children. It is estimated that between 50 and 100 genes are involved in the functioning of the ear. Mutations in any of those genes may cause hearing loss.

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    Cincinnati Children’s now offers OtoSeq, our next-generation sequencing panel of 23 genes associated with hearing loss. The panel was designed to identify approximately 80 percent of the genetic causes of early onset sensorineural hearing loss. Recently issued practice guidelines by the American College of Medical Genetics support the use of next-generation sequencing tests such as OtoSeq in the comprehensive evaluation of patients with hearing loss.

    > Download the OtoSeq Physician Guide for details.

    Why Choose Cincinnati Children’s for Genetic Testing?

    At Cincinnati Children's, we believe that a clinical perspective is crucial to the interpretation of genetic test results. That's why we have a practicing, board-certified pediatric otolaryngologist and molecular geneticist review and interpret each test result for the physician audience and make specific recommendations for your patients.

 
  • Diagnostic Test Sheets and Requisitions

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    Explore our Molecular Genetics Test Index
  • Why Use Complex Genetic Testing in Hearing Loss

    View webinar.

    Webinar features John Greinwald Jr., MD, and Jennifer Holle, CGC, discussing the value of high-throughput genetic testing as part of the sensorineural hearing loss evaluation.