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The Heart Institute Diagnostic Lab at Cincinnati Children’s provides viral PCR and genetic testing for DNA mutations associated with cardiovascular disease.
Current testing services include molecular analysis of viruses known to cause myocarditis and sequencing of genes associated with cardiac disease.
Download the complete HIDL Heterotaxy panel gene list. To order this panel, download the Heterotaxy requisition form or visit the Genetic Testing page.
*HIDL now offers direct insurance billing. Contact us at 513-803-1751 to learn more.
Our laboratory offers state-of-the-art molecular diagnostic testing for cardiovascular diseases. In 1986, the identification of Coxsackievirus B in the hearts of patients with myocarditis or dilated cardiomyopathy was reported. Subsequently, adenovirus was identified as another virus that is commonly found in the hearts of patients with these diseases, as well as a cause of organ rejection in patients with lung and/or heart transplants. More recently, we have shown that the predominant virus causing myocarditis and heart transplant rejection has again changed with parvovirus B19 now being most common. Our laboratory updates testing to reflect worldwide changes in viral infection. For example, we have already added PCR for Hepatitis C virus, an emerging cause of myocarditis in Southeast Asia.We offer rapid molecular testing of heart tissue, lung tissue, and other organ specimens and bodily fluids for viruses. These tests are focused specifically for viruses identified as causing heart disease in children and adults, as well as in the fetus. However, they have a wide range of other clinical applications. All testing is performed using PCR technology, thus providing optimal sensitivity and specificity.
The Heart Institute Diagnostic Lab provides genetic testing services for cardiovascular disease. Testing is available for connective tissue disorders, aortopathy, cardiomyopathy, cardiac arrhythmia, congenital heart disease, neuromuscular disease, and genetic syndromes including Barth syndrome, Holt-Oram syndrome, Marfan syndrome and heterotaxy syndrome.
Wenying Zhang, MD, PhDClinical Director
Phone: 513-803-1751 Fax: 513-803-1748 Email: HeartDx@cchmc.org
Access our Clinical Laboratory Test Index.
The Heart Institute Diagnostic Lab offers state-of-the art genetic and viral PCR testing with competitive prices and quick turn-around times.
Do you have questions? Unsure of what test to order?
Contact genetic counselor Amy Shikany at 513-803-1751 or email her at firstname.lastname@example.org.
Recently, the Heart Institute Diagnostic Lab was one of six labs awarded a grant from GenomeQuest in its next-generation sequencing lab grant program. HIDL will use the grant to apply NGS diagnostics to diagnosing congenital heart disease, adult and pediatric cardiomyopathy, and cardiovascular disorders with genetic syndromes.
Read more about this grant from GenomeQuest.
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