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The Heart Institute is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.
Andrew Redington, MD Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology email@example.com
Executive Co-Director, Heart Institute; Chief, Pediatric Cardiology
Professor, UC Department of Pediatrics
Dr. Redington comes to Cincinnati Children’s from The Hospital for Sick Children in Toronto, Ontario. His research interests include ventricular function, integrated physiology of congenital heart disease, and ischemic preconditioning. Dr. Redington has written more than 300 peer-reviewed publications, more than 30 book chapters, and has co-edited seven textbooks. He currently holds over 15 US and international patents.
Working with colleagues throughout the Heart Institute, his plans include building on the remarkable developments achieved in the recent past to establish a world-leading multidisciplinary team providing the highest quality clinical care and practice-changing research for children and adults with congenital heart disease.
Medical School: University of London.
Research Training: Doctorate of Medicine, University of London.
Fellowship: Adult cardiology, pediatric cardiology, The Royal Brompton Hospital, London, England.
Li J, Rohaila S, Gelber N, Rutka J, Sabah N, Gladstone R, Wei C, Kharbanda R, Redington AN. MicroRNA-144 is a circulating effector of remote ischemic preconditioning. Basic Research in Cardiology 2014: 109 (5): pp 423. (Sept)
Burns KM, Byrne BJ, Gelb BD, Kuhn B, Leinwand LA, Mital S, Pearson GD, Rodefeld M, Rossano JW, Stauffer BL, Taylor MD, Towbin JA, Redington AN. New mechanistic and therapeutic targets for pediatric heart failure: report from a national heart, lung, and blood institute working group. Circulation 2014: 130 (1): pp 79-86. (July)
Friedberg MK, Redington AN. Right versus left ventricular failure: differences, similarities, and interactions. Circulation 2014: 129 (9): pp 1033-1044. (Mar)
Friedberg MK, Cho MY, Li J, Assad RS, Sun M, Rohailla S, Honjo O, Apitz C, Redington AN. Adverse biventricular remodeling in isolated right ventricular hypertension is mediated by increased TGFβ1 signaling and is abrogated by angiotensin receptor blockade. American Journal of Respirology Cell Molecular Biology 2013: 49 (6): pp 1019-1028. (Dec)
Roche SL, Redington AN. Right ventricle: wrong targets? Another blow for pharmacotherapy in congenital heart diseases. Circulation 2013: 127 (3): pp 314-316. (Jan)
Hahn CD, Manlhiot C, Schmidt MR, Nielsen TT, Redington AN. Remote ischemic per-conditioning: A novel therapy for evolving stroke? Stroke 2011: 42 (10) pp 2960-2962.
Jean-St-Michel E, Manlhiot C, Li J, Tropak M, Michelsen MM, Schmidt MR, McCrindle BW, Slievert G, Wells GD, Redington AN. Remote Ischemic Preconditioning improves maximal performance in elite athletes. Medicine & Science of Sports & Exercise 2011: 43 (7): pp 1280-1286.
Wei M, Xin P, Li Y, Li J, Ma S, Wang L, Liu M, Li J, Zhu W, Redington AN. Repeated remote ischemic postconditioning protects against adverse left ventricular remodeling and improves survival in a rat model of myocardial infarction. Circulation Research 2011: 108 (10): pp 1220-1225.
Roche SL, Vogel M, Pitkanen O, Grant B, Slorach C, Fackoury C, Stephens D, Smallhorn J, Benson LN, Kantor PF, Redington AN. Isovolumic acceleration at rest and during exercise in children normal values for the left ventricle and first non-invasive demonstration of exercise-induced force-frequency relationships. Journal of American College of Cardiology 2011: 57 (9): pp 1100-1107.
Botker HE, Kharbanda R, Schmidt MR, Bottcher M, Kaltoft AK, Terkelsen CJ, Munk K, Anderson NH, Hansen TM, Trautner S, Lassen JF, Christiansen EH, Krusell LR, Kristensen SD, Thuesen L, Nielsen SS, Rehling M, Sorensen HT, Redington AN, Neilseu TT: Remote ischaemic conditioning before hospital admission, as a complement to angioplasty, and effect on myocardial salvage in patients with acute myocardial infarction: a randomized trial. Lancet 2010: 375 (9716): pp 727-734.
Jeffrey Robbins, PhD Director and Endowed Chair, Molecular Cardiovascular Biology 513-636-8098 firstname.lastname@example.org
Director and Endowed Chair, Molecular Cardiovascular Biology
Executive Co-Director, Heart Institute
Associate Chair, Children's Hospital Research Foundation
Structure function relationships for the contractile proteins; cardiac-specific gene manipulation in transgenic rabbits; the contractile protein myosin and human heart failure; molecular studies of human valve disease
Visit the Robbins Lab.
Gupta MK, Robbins J. Post-translational control of cardiac hemodynamics through myosin binding protein C. Pflugers Arch: European journal of physiology. 2014 Feb;466(2):231-6.
Mun JY, Previs MJ, Yu HY, Gulick J, Tobacman LS, Beck Previs S, Robbins J, Warshaw DM, Craig R. Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2170-5.
Sandri M, Robbins J. Proteotoxicity: An underappreciated pathology in cardiac disease. J Mol Cell Cardiol. 2014 Jun;71c:3-10.
Wang X, Robbins J. Proteasomal and lysosomal protein degradation and heart disease. J Mol Cell Cardiol. 2014 Jun;71c:16-24.
James J, Robbins J. Ablating a cardiac protein: Causality at last. Circ Res. 2013;112:1415-1419.
Razzaque MA, Gupta M, Osinska H, Gulick J, Blaxall BC, Robbins J. An endogenously produced fragment of cardiac myosin-binding protein C is pathogenic and can lead to heart failure. Circ Res. 2013 Aug 16;113(5):553-61.
Gupta MK, Gulick J, James J, Osinska H, Lorenz JN, Robbins J. Functional dissection of myosin binding protein C phosphorylation. J Mol Cell Cardiol. 2013;64C:39-50.
Bhuiyan MS, Pattison JS, Osinska H, James J, Gulick J, McLendon PM, Hill JA, Sadoshima J, Robbins J. Enhanced autophagy ameliorates cardiac proteinopathy. J Clin Invest. 2013;123(12):5284-97.
Pattison JS, Robbins J. Desmin and heart disease. In: Kavallaris M, ed. Cytoskeleton and human disease. New York, NY: Humana Press; 2012:411-424.
Bhuiyan MS, Gulick J, Osinska H, Gupta M, Robbins J. Determination of the critical residues responsible for cardiac myosin binding protein C's interactions. J Mol Cell Cardiol. 2012;53:838-847.
Cardiac Signaling in the Normal and Abnormal Heart. Principal Investigator. National Heart, Lung, and Blood Institute. Sep 2013-May 2018. #P01 HL69779.
Proteotoxicity: an underappreciated factor in cardiac disease. North American Coordinator. Leducq Transatlantic Alliance For Cardiovascular Disease. 2011-2016.
Clifford Chin, MD Co-Director, Advanced Cardiomyopathy Services, Heart Institute 513-803-3151 email@example.com
Co-Director, Advanced Cardiomyopathy Services, Heart Institute
Pediatric cardiology; cardiomyopathy and transplantation
MD: SUNY Downstate Medical Center, Brooklyn, NY, 1989.
Residency: Pediatrics, University of California Davis Medical Center, Sacramento, CA, 1989.
Fellowship: Stanford University, Stanford, CA, 1992.
Castleberry C, Ryan T, Chin C. Transplantation in the Highly Sensitized Pediatric Patient. Circulation. 2014;129:2313-2319.
Chin C. Pediatric Antibody Mediated Rejection. Pediatric Transplantation. 2012;16:404-4012.
Pietra B, Kantor P, Bartlett H, Chin C, Canter C, Larsen R, Edens E, Colan C, Towbin T, Lipshultz S, Kirklin J, Naftel D, Sleeper L, Hsu D. Early Predictors of Survival to and After Clinical Heart Transplantation in Children’ with Dilated Cardiomyopathy. Circulation. 2012;126:1079-86.
Chin C, Chen G, Sequeria F, Berry G, Siehr S, Bernstein D, Rosenthal D, Reinhartz O, Tyan D. Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients. J Heart Lung Transplant. 2011 Feb;30(2):158-63.
Chin C, Lukito SS, Shek J, Bernstein D, Perry SB. Prevention of pediatric graft coronary artery disease: atorvastatin. Pediatr Transplant. 2008 Jun;12(4):442-6.
Potena L, Fearon WF, Sydow K, Holweg C, Luikart H, Chin C, Weisshaar D, Mocarski ES, Lewis DB, Valantine HA, Cooke JP. Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. Transplantation. 2008 Mar 27;85(6):827-33.
Tu W, Potena L, Stepick-Biek P, Liu L, Dionis KY, Luikart H, Fearon WF, Holmes TH, Chin C, Cooke JP, Valantine HA, Mocarski ES, Lewis DB. T-cell immunity to subclinical cytomegalovirus infection reduces cardiac allograft disease Circulation. 2006 Oct 10;114(15):1608-15.
Potena L, Holweg CT, Chin C, Luikart H, Weisshaar D, Narasimhan B, Fearon WF, Lewis DB, Cooke JP, Mocarski ES, Valantine HA. Acute rejection and cardiac allograft vascular disease is reduced by suppression of subclinical cytomegalovirus infection. Transplantation. 2006 Aug 15;82(3):398-405.
Chin C, Naftel D, Pahl E, Shankel T, Clark ML, Gamberg P, Kirklin J, Webber S; Pediatric Heart Transplant Study. Cardiac re-transplantation in pediatrics: a multi-institutional study. J Heart Lung Transplant. 2006 Dec;25(12):1420-4.
Chin C, Naftel DC, Singh TP, Blume ED, Luikart H, Bernstein D, Gamberg
P, Kirklin JK, Morrow WR, Pediatric Heart Transplant Study Group. Risk
factors for recurrent rejection in pediatric heart transplantation: a
multicenter experience. J Heart Lung Transplant. 2004 Feb;23(2):178-85.
David S. Cooper, MD, MPH Chief Safety Officer, Heart Institute 513-803-5448 firstname.lastname@example.org
Chief Safety Officer, Heart Institute
Associate Medical Director, Cardiovascular Intensive Care Unit
Co-Director, Center for Acute Care Nephrology
Medical Director, Cardiac Extracorporeal Life Support Program
Associate Professor, UC Department of Pediatrics
Pediatric cardiac critical care; patient safety; extracorporeal life support
Dr. Cooper is board certified in Pediatrics, Pediatric Cardiology and Pediatric Critical Care. He is currently the Heart Institute Safety Officer, Co-Director of the Center for Acute Care Nephrology, Director of the Cardiac ECMO Program and Associate Medical Director of the CICU at Cincinnati Children’s Hospital Medical Center.
Dr. Cooper's career over the past 10 years has focused on the care of critically ill neonates, infants, children, adolescents and adults with complex congenital heart disease (CHD). He has a particular interest in how care in the intensive care unit can impact morbidity with a specific interest in hematologic, infectious and renal morbidities. Additionally, Dr. Cooper has had extensive involvement with the Pediatric Cardiac Critical Care Consortium (PC4), including the development of the PC4 CICU database that will be used to track outcomes and improve outcomes for patients with critical cardiac disease.
MD: University of South Florida College of Medicine, Tampa, Florida, 1996.
MPH: University of South Florida College of Public Health, Tampa, Florida, 1999.
Residency: All Children’s Hospital, University of South Florida, St. Petersburg, FL.
Fellowships: Cardiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH; Critical Care, Children’s Medical Center Dallas, UT Southwestern, Dallas, Texas.
Certifications: American Board of Pediatrics; American Board of Pediatrics, Sub-board of Pediatric Cardiology; American Board of Pediatrics, Sub-board of Pediatric Critical Care.
DeSena HC, Nelson DP, Cooper DS. Cardiac Intensive Care for the Neonate and Child After Cardiac Surgery. Current Opinion in Cardiology. 2015 Jan;30(1):81-8.
Kwiatkowski DM, Menon S, Krawczeski CD, Goldstein SL, Morales DL, Philips A, Manning PB, Eghtesady P, Wang Y, Nelson DP, Cooper DS. Improved Outcomes with Peritoneal Dialysis Catheter Placement after Cardiopulmonary Bypass in Infants. Journal of Thoracic and Cardiovascular Surgery. 2015 Jan;149(1):230-6.
Gaies M, Cooper DS, Tabbutt S, Schwartz SM, Ghanayem N, Chanani NK, Costello JM, Thiagarajan RR, Laussen PC, Shekerdemian LS, Donohue JE, Willis GM, Gaynor JW, Jacobs JP, Ohye RG, Charpie JR, Pasquali SK, Scheurer MA. Collaborative quality improvement in the cardiac intensive care unit: development of the Paediatric Cardiac Critical Care Consortium (PC4). Cardiol Young. 2014 Aug;28:1-7.
Jolley M, Thiagarajan R, Salvin J, Barrett C, Cooper DS, Teele S. ECMO in Patients with Superior Cavopulmonary Anastomosis (Glenn). Journal of Thoracic and Cardiovascular Surgery. 2014;148(4):1512-8.
Costello JM, Pasquali SK, He X, Jacobs JP, Hill KD, Cooper DS, Baker CL, Jacobs ML. Gestational Age at Birth and Outcomes after Neonatal Cardiac Surgery: An Analysis of the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database. Circulation. 2014;129:2511-2517.
Tabbutt S, Ghanayem N, Ravishankar C, Sleeper LA, Cooper DS, Frank DU, Lu M, Pizarro C, Frommelt P, Goldberg CS, Graham EM, Krawczeski CD, Lai WW, Lewis A, Kirsh JA, Mahony L, Ohye RG, Simsic J, Lodge AJ, Spurrier E, Stylianou M, Laussen P, Pediatric Heart Network Investigators. Risk factors for hospital morbidity and mortality after the Norwood procedure: A report from the Pediatric Heart Network Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012 Oct;144(4):882-95.
Ghanayem NS, Allen KR, Tabbutt S, Atz AM, Clabby ML, Cooper DS, Eghtesady P, Frommelt PC, Gruber PJ, Hill KD, Kaltman JR, Laussen PC, Lewis AB, Lurito KJ, Minich LL, Ohye RG, Schonbeck JV, Schwartz SM, Singh RK, Goldberg CS, Pediatric Heart Network Investigators. Interstage mortality after the Norwood procedure: Results of the multicenter Single Ventricle Reconstruction trial. J Thorac Cardiovasc Surg. 2012 Oct;144(4):896-906.
Cooper DS, Charpie JR, Flores FX, Gaynor JW, Salvin JW, Devarajan P, Krawczeski CD. Acute kidney injury and critical cardiac disease. World J Ped Congen Heart Surg. 2011;2:411-423.
Jacobs JP, Asante-Korang A, O'Brien SM, Chai PJ, Dadlani GH, Rodriguez-Fazzi GL, Vu D, McCormack J, McKenna DE, Boucek RJ Jr, Cooper DS, Saltiel A, Carapellucci J, van Gelder HM, Daicoff GR, Quintessenza JA. Lessons learned from 119 consecutive cardiac transplants for pediatric and congenital heart disease. Ann Thorac Surg. 2011 Apr;91(4):1248-54.
Pilchard J, Dadlani G, Andropoulos D, Jacobs JP and Cooper DS. Intensive care and perioperative management of patients with complete atrioventricular septal defect. World J Ped Congen Heart Surg. 2010 Apr;1:105-111.
Evaluation of the Pharmacokinetics of ATIII in Neonates and Infants Undergoing CPB and ECMO Support. Principal Investigator. Grifols. 2014-present.
A Randomized, Placebo Controlled, Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Intravenous (IV) Acetaminophen for the Treatment of Acute Pain in Pediatric Patients. Site Principal Investigator. Cadence. 2014-present.
Use of acute kidney injury biomarkers to predict impaired milrinone pharmacokinetics in children. Mentor. Thrasher grant. 2013-present.
Extracorporeal Life Support Organization (ELSO) Research Grant. Principal Investigator. Extracorporeal Life Support Organization. 2012-present.
Thomas R. Kimball, MD Medical Director, Heart Institute 513-636-8270 email@example.com
Medical Director, Heart Institute
Congential heart disease; echocardiography; cardiac imaging
Thomas R. Kimball, MD, is a professor of pediatrics with the University of Cincinnati College of Medicine and is currently the medical director of the Heart Institute at Cincinnati Children's Hospital Medical Center.
A native of California, Dr. Kimball graduated with distinction and honors from Stanford University. He earned his medical degree from New York University, New York, NY. He completed his pediatric internship and residency at Children's Hospital of Los Angeles and his pediatric cardiology fellowship at Cincinnati Children's Hospital Medical Center.
Dr. Kimball has been an attending staff member of the Division of Cardiology at Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine since 1988.
Dr. Kimball's academic interests relate to echocardiography and he has made numerous scholarly contributions in the field of ventricular function utilizing echocardiography, particularly in the field of hypertension and obesity.
He has established collaborative relationships with basic scientists at the University of Cincinnati College of Medicine using echocardiography to evaluate phenotypes of transgenic mice, including embryonic mice.
Dr. Kimball has been active in the cardiology community. He is a member of the American Society of Echocardiography, American Heart Association, American Academy of Pediatrics, American College of Cardiology and an investigator in the NIH Pediatric Heart Network.
He was also a member of the first Family Advisory Council at Cincinnati Children's and received the 2006 Family Advisory Council Award of Excellence.
In 2010, he was made the medical director of the Heart Institute at Cincinnati Children's.
BS: Stanford University with Honors and Distinction, Stanford, CA, 1978.
MD: New York University School of Medicine, New York City, NY, 1982.
Residency: Children's Hospital of Los Angeles, Los Angeles, CA, 1985.
Fellowship: Children's Hospital Medical Center, Cincinnati, OH, 1988.
Certification: Pediatrics, 1986; Pediatric Cardiology, 1991 (recertification, 1997, 2004).
Shah AS, Gao Z, Urbina EM, Kimball TR, Dolan LM. The effects of arterial thickness and stiffness in obese youth. Journal of Clinical Endocrinology Metabolism. 2014 Mar;99(3):1037-43.
Alghamdi M, De Souza AM, White CT, Potts MT, Warady BA, Furth SL, Kimball TR, Potts JE, Sandor GG. Response to: echocardiography assessment of the aorta in children with chronic kidney disease. Pediatric Cardiology. 2014 Jan;35(1):183-4.
Uzark K, King E, Spicer R, Beekman R, Kimball T, Varni J. The clinical utility of health-related quality of life assessment in pediatric cardiology outpatient practice. Congenital Heart Disease. 2013 May;8(3):211-8.
Madueme PC, Khoury PR, Urbina EM, Kimball TR. Predictors of exaggerated exercise-induced systolic blood pressures in young patients after coarctation repair. Cardiology In The Young. 2013 Jun;23(3):416-22.
Alghamdi M, De Souza A, White CT, Potts MT, Warady BA, Furth SL, Kimball T, Potts JE, Sandor GG. Echo-Doppler assessment of the biophysical properties of the aorta in children with chronic kidney disease. Pediatric Cardiology. 2013 Jun;34(5):1218-25.
Urbina EM, Khoury PR, McCoy CE, Dolan LM, Daniels SR, Kimball TR. Triglyceride to HDL-C ratio and increased arterial stiffness in children, adolescents and young adults. Pediatrics. 2013 Apr;131(4):E1082-90.
Shah AS, Urbina EM, Khoury PR, Kimball TR, Dolan LM. Lipids and lipoprotein ratios: Contribution to carotid intima media thickness in adolescents and young adults with type 2 diabetes mellitus. Journal of Clinical Lipidology. 2013 Sept-Oct;7(5):441-445.
Kimball TR. Echocardiography in the Assessment of Cardiovascular Disease Risk. In: Eduardo M. da Cruz, Dunbar Ivy, James Jaggers, editors, Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care. Springer-Verlag London 2013. ISBN:978-1-4471-4618-6.
Kimball TR, Michelfelder EC. Echocardiography: Basic Principles and Imaging. In: Allen HD, Driscoll DJ, Shaddy RE, Feltes TF, editors. Moss & Adams' Heart Disease in Infants, Children and Adolescents: Including the Fetus and Young Adult. 1. Philadelphia, PA: Lippincott Williams & Wilkins; 2012. p. 134-71.
Shah AS, Dolan LM, Gao Z, Kimball TR, Urbina EM. Racial differences in arterial stiffness among adolescents and young adults with type 2 diabetes. Pediatric Diabetes. 2012 Mar;13(2):170-5.
Lisa A. Lee, MD Director, Community Based Cardiology, Heart Institute 859-344-4732 firstname.lastname@example.org
Director, Community Based Cardiology, Heart Institute
Assistant Professor, UC Department of Pediatrics
Pediatric cardiology; outpatient community based services
BA: Molecular, Cellular and Developmental Biology, University of Colorado, Boulder, CO, 1989.
MD: University of Cincinnati College of Medicine, Cincinnati, OH, 1993.
Residency: Cincinnati Children's Hospital, Cincinnati, OH, 1993-1996.
Fellowships: Pediatric Resident, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 1994-1996; Pediatric Cardiology, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 1997-2000; Pediatric Echocardiography, Cincinnati Children's Hospital, Cincinnati, OH, 2000-2001.
Certification: Pediatrics, 1996; Pediatric Cardiology, 2000.
Lee LA. Innocent murmurs. Presented to the family practice residents and St. Elizabeth Medical Center, Edgewood, KY. January 10, 2003
Lee LA. Stress echocardiography in children. Pediatric Ultrasound Today. 2001 Volume 6, Lesson 4.
Lee LA, Goya G, Witt SA, Flascock BJ, Mays W, Kimball TR. Resting predictors of latent stress-induced left ventricular outflow tract obstruction in young patients with hypertrophic cardiomyopathy. J Am Coll Cardiology. 2001 Oct.
Lee LA. Evaluation and management of hypertension in children. Presented to nurse practitioner students, University of Michigan School of Nursing, Ann Arbor, MI. March 2000.
Lee LA, Simon C, Bove EL, Mosca RS, Ebbini ES, Abrams GD, Ludomirsky A. High-intensity focused ultrasound effect on cardiac tissues: potential for clinical application. Echocardiography. 2000 Aug; 17(6 Pt 1):563-6.
Ohye RG, Kagisaki K, Lee LA, Mosca RS, Goldberg CS, Bove EL. Biventricular repair for aortic atresia or hypoplasia and ventricular septal defect. J Thorac Cardiovasc Surg. 1999;118(4):648-53.
Lee LA, Kimball TR, Daniels SR, Khoury P, Meyer RA. Left ventricular mechanics in the preterm infant and their effect on the measurement of cardiac performance. J Pediatr. 1992 Jan;120(1):114-9.
David L. S. Morales, MD Chief of Cardiovascular Surgery, Heart Institute, Cardiothoracic Surgery 513-803-9150 email@example.com
Chief of Cardiovascular Surgery, Heart Institute, Cardiothoracic Surgery
Clark-Helmsworth Chair of Cardiovascular Surgery
UC Division of Surgery
Congenital heart surgery; heterotaxy syndrome; pediatric heart and lung transplantation; mechanical circulatory support
MD: Yale University School of Medicine, New Haven, CT.
Residency: General and cardiothoracic surgery, New York-Presbyterian Medical Center, Columbia University, New York, NY.
Fellowships: Congenital heart surgery, Texas Children’s Hospital, Baylor University, Waco, TX.
Board certifications: Surgery, thoracic surgery, congenital heart surgery.
David P. Nelson, MD, PhD Director, Cardiac Intensive Care 513-803-1801 firstname.lastname@example.org
Director, Cardiac Intensive Care
Neurodevelopmental outcomes; family-centered care; cardiopulmonary interactions; physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure; cardio-renal syndrome; end of life care
David P. Nelson, MD, PhD, completed his fellowship in pediatric critical care at Harvard University, Boston Children’s Hospital. He served as the co-director of Cardiac Intensive Care at Cincinnati Children’s Hospital Medical Center from July 1996 to August 2005. In September of 2005, Dr. Nelson served as the director of Cardiac Intensive Care at Texas Children’s Hospital for four years before rejoining Cincinnati Children's as the director of Cardiac Intensive Care in 2009.
Dr. Nelson’s clinical interests include neurodevelopmental outcomes in children with acquired and congenital disease; family-centered care; cardiopulmonary interactions and the physiology of non-conventional circulations; endocrine abnormalities in cardiac intensive care; management of acute decompensated heart failure in children; cardio-renal syndrome and end-of-life care.
His research focuses on quality of life and neurodevelopmental outcomes in children with acquired and congenital heart disease; etiology of adrenal dysfunction in cardiac intensive care; inflammatory organ system injury and congenital heart surgery.
PhD: University of Chicago, Chicago, IL, 1987.
MD: University of Chicago Pritzker School of Medicine, Chicago, IL, 1989.
Residency: University of Washington-Children’s Hospital Medical Center, Seattle, WA, 1989-1992.
Fellowship: Harvard University, Boston Children’s Hospital, Boston, MA, 1992-1994.
Certification: Pediatrics, 1992; Pediatric Cardiology, 1994; Pediatric Critical Care, 1998.
Moffett BS, McDade E, Rossano JW, Dickerson HA, Nelson DP. Enteral potassium supplementation in a pediatric cardiac intensive care unit: Evaluation of a practice change. Pediatr Crit Care Med. 2011 Feb 3.
Jefferies JL, Hoffman TM, Nelson DP. Heart failure treatment in the intensive care unit in children. Heart Fail Clin. 2010 Oct;6(4):531-58, ix-x. Review.
Carlo WF, Nelson DP. Inhaled nitric oxide improves oxygen saturation in children with pulmonary arteriovenous malformations after the Fontan procedure. Pediatr Crit Care Med. 2010 Aug 5.
Giuliano JS Jr, Lahni PM, Bigham MT, Manning PB, Nelson DP, Wong HR, Wheeler DS. Plasma angiopoietin-2 levels increase in children following cardiopulmonary bypass. Intensive Care Med. 2008 Oct;34(10):1851-7.
Moffet, BS, AR Mott, DP Nelson, KD Gurwitch. Medication dosing and renal insufficiency in a pediatric cardiac intensive care unit: impact of pharmacist consultation. Pediatr Cardiol. 2008 29(4):744-8.
Wheeler DS, Dent CL, Manning PB, Nelson DP. Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young. 2008 Feb;18(1):41-50.
Price JF, AR Mott, DP Nelson, AC Chang, E O'Brian Smith, JA Towbin, WJ Dreyer, SW Denfield, SL Goldstein. Worsening renal function in children hospitalized with decompensated heart failure: evidence for a pediatric cardiorenal syndrome. Pediatr Crit Care Med. 2008 9(3):279-84.
Moffett, BS, AR Mott, D.P. Nelson, SL Goldstein, JL Jefferies. Renal effects of fenoldopam in critically ill pediatric patients: A retrospective review. Pediatr Crit Care Med. 2008 9(4):403-406.
Rossano JW, MD Taylor, EO Smith, CD Fraser, Jr., ED McKenzie, JF Price, HA Dickerson, DP Nelson, AR Mott. Glycemic profile in infants who have undergone the arterial switch operation: Hyperglycemia is not associated with adverse events. J Thorac Cardiovasc Surg. 2008 135(4):739-45.
Wheeler, DS, CL Dent, PB Manning, DP Nelson. Factors prolonging length of stay in the cardiac intensive care unit following the arterial switch operation. Cardiol Young. 2008 18(1):41-50.
Wheeler, DS, JM Pearl, PB Manning, SM Schwartz, CL Dent, P Khoury, DP Nelson. Factors Prolonging Cardiac Intensive Care Unit Stay after neonatal congenital heart surgery. Pediatr Crit Care Med. 2008 18(1):41-50.
James P. Spaeth, MD Director, Cardiac Anesthesia 513-636-4408 email@example.com
Director, Cardiac Anesthesia
Staff Anesthesiologist, Department of Anesthesia
Associate Professor, UC Department of Anesthesiology
Cardiac anesthesia; neurologic injury in children with congenital heart disease; improving perioperative safety
MD: University of Virginia School of Medicine, Charlottesville, VA, 1993.
Internship: Internal Medicine, University of Virginia Medical Center, Charlottesville, VA, 1994.
Residency: Anesthesiology, University of California, San Diego Medical Center, San Diego, CA, 1997.
Fellowship: Pediatric Anesthesiology, Children's Hospital of Philadelphia, Philadelphia, PA, 1998.
Certification: Anesthesiology, 1998.
Gunter JB, McAuliffe JJ, Beckman EC, Wittkugel EP, Spaeth JP, Varughese AM. A factorial study of ondansetron, metoclopramide, and dexamethasone for emesis prophylaxis after adenotonsillectomy in children. Paediatr Anaesth. 2006 Nov;16(11):1153-65.
Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2006 Jan;131(1):190-7.
Aronson LA, Spaeth JP. Frontiers in pediatric anesthesia: cardiac anesthesia. Int Anesthesiol Clin. 2006 Winter;44(1):33-49.
Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg. 2005 Dec;130(6):1523-30.
Loepke AW, Spaeth JP. Glucose and Heart Surgery: Neonates Are Not Just Small Adults. Anesthesiology. 2004 Jun;100(6):1345-52.
Baker RC, Schubert CJ, Kirwan KA, Lenkauskas SM, Spaeth JT. After-hours telephone triage and advice in private and nonprivate pediatric populations. Arch Pediatr Adolesc Med. 1999 Mar;153(3):292-6.
Betsy Adler, RN, APRN, CPNP Nurse Practitioner, Heart Institute 613-636-4770 firstname.lastname@example.org
Nurse Practitioner, Heart Institute
RN: University of Cincinnati, Cincinnati, Ohio, 1994.
MS: Nursing, University of Cincinnati, Cincinnati, Ohio, 1997.
Certification: Pediatric Nurse Practitioner, 1997.
Janene R. Allen, MSN, APRN, CPNP Nurse Practitioner, Heart Institute 513-636-0911 email@example.com
Jeffrey B. Anderson, MD, MPH, MBA Chief Quality Officer, Heart Institute 513-636-3865 firstname.lastname@example.org
Chief Quality Officer, Heart Institute
Pediatric electrophysiology; syncope; quality improvement and outcomes
Following his cardiology fellowship, Dr. Anderson helped establish the Syncope Clinic in the Heart Institute at Cincinnati Children’s Hospital Medical Center, and he continues to direct the work in this clinic.
Dr. Anderson helped develop the Safety, Quality, Value program within the Heart Institute at Cincinnati Children's Hospital Medical Center. The Heart Institute’s Safety, Quality, and Value team provides a platform of core data management, analytic, quality improvement, and project management expertise focused specifically on the Heart Institute’s strategic priority areas related to safety, quality, and value. This team serves a supporting role to further the Heart Institute’s ability to achieve its mission of being the leader in clinical outcomes, experience, and value for patients and families who receive diagnostic and interventional services for congenital and acquired heart disease.
MD: University of Utah School of Medicine, Salt Lake City, UT, 2002.
Masters of Public Health: University of Utah School of Medicine, Salt Lake City, UT, 2002.
Residency: Pediatrics, University of North Carolina,Chapel Hill, NC, 2002-2006.
Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2006-2009.
Fellowship: Pediatric Electrophysiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2009-2010.
Masters of Business Administration: Ross School of Business, University of Michigan, Ann Arbor, MI, 2013.
Anderson J, Grenier M, Edwards N, Madsen N, Czosek R, Spar D, Barnes A, Pratt J, King E, Knilans T.Usefulness of Combined History, Physical Examination, Electrocardiogram and Limited Echocardiogram in Screening Adolescent Athletes for Risk for Sudden Cardiac Death. Am J Cardiol. 2014 Dec 1;114(11):1763-7.
Anderson JB, Beekman RH 3rd, Kugler JD, Rosenthal GL, Jenkins KJ, Klitzner TS, Martin GR, Neish SR, Darbie L, King E, Lannon C. Improvement in growth in infants with single ventricle using a learning collaborative. National Pediatric Cardiology Quality Improvement Collaborative. Congenit Heart Dis. 2014 Nov;9(6):512-20.
Burch PT, Gerstenberger E, Ravishankar C, Hehir DA, Davies RR, Colan SD, Sleeper LA, Newburger JW, Clabby ML, Williams IA, Li JS, Uzark K, Cooper DS, Lambert LM, Pemberton VL, Pike NA, Anderson JB, Dunbar-Masterson C, Khaikin S, Zyblewski SC, Minich LL. Longitudinal assessment of growth in hypoplastic left heart syndrome: results from the single ventricle reconstruction trial. J Am Heart Assoc. 2014 Jun 27;3(3).
Slicker J, Hehir DA, Horsley M, Monczka J, Stern KW, Roman B, Ocampo EC, Flanagan L, Keenan E, Lambert LM, Davis D, Lamonica M, Rollison N, Heydarian H, Anderson JB. Nutrition Algorithms for Infants with Hypoplastic Left Heart Syndrome; Birth Through the First Interstage Period. Congenital Heart Disease. 2013 Mar-April;8(2)89-102.
Anderson JB, Czosek RJ, Knilans TK, Marino BS.The Effect of Paediatric Syncope on Health-Related Quality of Life. Cardiol Young. 2012 Oct;22(5):583-588.
Anderson J, Czosek R, Cnota J, Meganathan K, Knilans T, Heaton P. Pediatric syncope: National Hospital Ambulatory Medical Care Survey results. J Emerg Med. 2012 Oct;43(4):575-83.
Anderson J, Iyer S, Schidlow D, Williams R, Varadarajan K, Horsley M, Slicker J, Pratt J, King E, Lannon C. Variation in growth of infants with a single ventricle. J Pediatr. 2012 Jul;161(1):16-21.
Anderson J, Eghtesady P, Kalkwarf HJ, Kehl JE, Marino BS. Low weight-for-age z-score and infection risk following Fontan procedure. Ann Thorac Surg. 2011 May;91(5):1460-6.
Anderson J, Beekman RH, Eghtesady P, Uzark K, Kalkwarf HJ, Kehl JE, Marino BS.Predictors of poor weight gain in infants with a single ventricle. J Pediatr. 2010 Sep;157(3):407-13, 413.e1.
Anderson JB, Beekman RH, 3rd, Border WL, Kalkwarf HJ, Khoury PR, Uzark K, Eghtesady P, Marino BS. Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle. J Thorac Cardiovasc Surg. 2009;138(2):397-404.
Robert H. Beekman III, MD 513-636-7072 email@example.com
Cardiac catheterization; intervention for congenital heart disease; quality improvement
Robert H. Beekman, III, MD, is currently professor of pediatric cardiology at Children's Hospital Medical Center of Cincinnati within the University of Cincinnati College of Medicine. Dr. Beekman's subspecialty interests involve cardiovascular physiology, interventional pediatric cardiology and clinical quality improvement.
A native of California, Dr. Beekman graduated from Occidental College in Los Angeles, and earned his MD from Duke University in Durham, NC. Dr. Beekman completed his pediatric internship and residency at UCLA Medical Center, and his pediatric cardiology fellowship at the University of Michigan Medical Center, Ann Arbor, Mich. Dr. Beekman also obtained a master's degree in statistical analysis and research design from the University of Michigan. From 1985-1996, Dr. Beekman was a member of the Division of Pediatric Cardiology at the University of Michigan School of Medicine. From 1996-2009 he was director of Cardiology at Children's Hospital Medical Center of Cincinnati, and professor of pediatrics at the University of Cincinnati School of Medicine.
Dr. Beekman is passionate about improving care for patients born with congenital heart disease, and throughout his career has been an active clinician and educator. Dr. Beekman's academic interests relate to cardiovascular physiology, cardiac catheterization and quality improvement. He has published more than 200 manuscripts in cardiology and pediatric journals. Dr. Beekman is the chair of the JCCHD National Pediatric Cardiology Quality Improvement Collaborative and chair of the ACC Adult Congenital and Pediatric Cardiology Section. He has been chair of the Section on Cardiology and Cardiac Surgery of the American Academy of Pediatrics and president of the Society of Pediatric Cardiology Training Program Directors.
MD: Duke University School of Medicine, Durham, NC, 1976.
MS: Clinical Research Design and Statistics, University of Michigan, Ann Arbor, MI, 1986.Residency: Pediatrics, UCLA Medical Center, Los Angeles, CA, 1976 to 1979.Fellowship: Pediatric Cardiology, CS Mott Children's Hospital, University of Michigan, Ann Arbor, MI, 1979 to 1982.Certification: Pediatrics, 1981; Pediatric Cardiology, 1983.
Seckeler MD, Hirsch R, Beekman RH, Goldstein BH. A new predictive equation for oxygen consumption in children and adults with congenital and acquired heart disease. Heart. 2015;101(7):517-524.
Brown DW, Cohen KE, O’Brien P, Gauvreau K, Klitzner TS, Beekman RH, Kugler JD, Martin GR, Neish SR, Rosenthal GL, Lannon C, Jenkins KJ. Impact of prenatal diagnosis in survivors of initial palliation of single ventricle heart disease: Analysis of the National Pediatric Cardiology Quality Improvement Collaborative database. Pediatr Cardiol. 2015;36(2):314-321.
Anderson JB, Beekman RH, Kugler JD, Rosenthal GL, Jenkins KJ, Klitzner TS, Martin GR, Neish SR, Darbie L, King E, Lannon C. Use of a learning network to improve variation in interstage weight gain after the Norwood operation. Congenital Heart Disease. 2014;9(6):512-520.
Moore J, Vincent R, Beekman R, Benson L, Bergersen L, Holzer R, Jayaram N, Jenkins K, Li Y, Ringel R, Rome J, Martin G. Procedural results and safety of common interventional procedures in congenital heart disease: Initial report from the National Cardiovascular Data Registry. J Am Coll Cardiol. 2014;64:2439-2451.
Zussman M, Hirsch R, Beekman RH, Goldstein BH. Impact of percutaneous interventions for pulmonary artery stenosis in Alagille syndrome. Congenital Heart Disease. 2014.
Villafane J, Lantin-Hermoso MR, Bhatt AB, Tweddell JS, Geva T, Nathan M, Elliott MJ, Vetter VL, Paridon SM, Kochilas L, Jenkins KJ, Beekman RH, Wernovsky G, Towbin JA. D-Transposition of the great arteries: The current era of the arterial switch operation. J Am Coll Cardiol. 2014;64:498-511.
Armsby L, Beekman RH, Benson L, Fagan T, Hagler D, Hijazi ZM, Holzer R, Ing F, Kreutzer J, Lang P, Levi D, Latson L, Moore P, Mullins C, Ruiz C, Vincent R.SCAI expert consensus statement for advanced training programs in pediatric and congenital interventional cardiac catheterization. Cath and Cardiovasc Intervent. 2014.
Villafane J, Baker GH, Austin E, Miller S, Peng L, Beekman R. Melody pulmonary valve bacterial endocarditis: Experience in four pediatric patients and a review of the literature. Cath and Cardiovasc Intervent. 2014;84:212-218.
Lin CH, Hegde S, Marshall AC, Porras D, Gauvreau K, Beekman RH, Torres A, Vincent JA, Moore JW, Holzer R, Armsby L, Bergersen L. Incidence and management of life threatening adverse events during cardiac catheterization for congenital heart disease. Pediatric Cardiology. 2014;35:140-148.
Baker-Smith CM, Wilhelm CM, Neish SR, Klitzner TS, Beekman RH, Kugler JD, Martin GR, Lannon C, Jenkins KJ, Rosenthal GL. Predictors of prolonged length of intensive care unit stay after Stage I palliation: A report from the National Pediatric Cardiology Quality Improvement Collaborative. Pediatric Cardiol. 2014;25(3):431-440.
George Benzing III, MD 513-636-8266 firstname.lastname@example.org
Emeritus, UC Department of Pediatrics
Critical cardiac care
MD: University of Cincinnati, Cincinnati, Ohio, 1958.
Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio.
Fellowship: Pediatric Cardiology, Children's Hospital Medical Center, Cincinnati, Ohio.
Certification: Pediatrics, 1963; Pediatric Cardiology, 1964.
Nicole M. Brown, MD 513-636-4432 email@example.com
MD: University of Cincinnati, Cincinnati, OH.
Residency: Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Fellowship: Pediatric Cardiology, Children's Hospital of Pittsburgh, Pittsburgh, PA.
Jonathan W. Byrnes, MD Attending Cardiac Intensivist, Cardiac Intensive Care Unit 513-803-1801 firstname.lastname@example.org
Attending Cardiac Intensivist, Cardiac Intensive Care Unit
Jonathan Byrnes, MD, is an assistant professor of pediatrics with the University of Cincinnati College of Medicine and an attending cardiac intensivist in Cincinnati Children’s Hospital Medical Center’s Cardiac Intensive Care Unit. He joined the faculty in July 2013.
A native of Mississippi, Dr. Byrnes graduated with honors from University of Mississippi and earned his medical degree from University of Mississippi Medical Center in 2005. He completed his pediatric residency at Blair Batson Children's Hospital in Jackson, MS and a combined fellowship in cardiology and critical care medicine at Arkansas Children's Hospital. Dr. Byrnes’s clinical interests are providing superb, cost-effective care and delivering cohesive management amongst all specialties in the cardiac intensive care unit.
Dr. Byrnes is active in clinical and translational research involving extracorporeal life support that would benefit critically ill children. This research is primarily focused on the biocompatibility of the patient / device interface and the associated interaction of the coagulation and inflammatory pathways. The aim of these endeavors is to ultimately decrease the incidence of end organ dysfunction and stroke associated with these therapies.
MD: University of Mississippi Medical Center, Jackson, MS, 2005.
Residency: Pediatrics, University of Mississippi Medical Center, Jackson, MS, 2008.
Fellowships: Combined Pediatric Cardiology and Pediatric Critical Care Medicine, Arkansas Children's Hospital, University of Arkansas Medical Sciences, Little Rock, AR, 2013.
Certification: American Board of Pediatrics, 2008.
Prodhan P, Imamura M, Garcia X, Byrnes J, Bhutta A, Dyamenahalli U. Abdominal Compartment Syndrome in Newborns and Children supported on Extracorporeal Membrane Oxygenation. ASAIO J. 2012;58(2): 143-147.
Byrnes J, Williams B, Prodhan P, Erdem E, Williamson R, Gautam N, James C, Jaquiss R, Imamura M, Bhutta A. Successful intra-arterial thrombolytic therapy for a right middle cerebral artery stroke in a 2-year old supported by a ventricular assist device. Transpl Int. 2012;25(3): e31-33.
Byrnes J, W McKamie, C Swearingen, Gossett J, Prodhan P, Bhutta A, Jaquiss R, Imamura M, Fiser R. Hemolysis during Cardiac Extracorporeal Membrane Oxygenation: A Case-Control Comparison of a Roller Pump and a Centrifugal Pump in a Pediatric Population. ASAIO J. 2011 Sep-Oct;57(5):456-61.
Byrnes J, Prodhan P, Imamura M, Frazier E. Accidental Azygos Vein Extracorporeal Membrane Oxygenation Cannulation in a Neonate with Premature Closure of the Ductus Arteriosus. ASAIO J. 2011 Jul-Aug; 57(4): 344-5.
Michelle C. Cash, MSN, APRN, CNP Nurse Practitioner, Heart Institute 513-803-0695 email@example.com
Pediatrics; pulmonary hypertension
Michelle has been working in cardiology exclusively since becoming a nurse practitioner. She has a special interest in caring children with pulmonary hypertension and their families. She is very involved with the Pulmonary Hypertension Association, serving in many capacities, to ensure that her patients are receiving the best care. Michelle continues to partner with Dr. Russel Hirsch in their clinical and research endeavors to improve care for children with pulmonary hypertension.