• Genetic Testing for Heritable Liver Diseases

    Heritable Liver Disease Genetic Testing program.

    The Cincinnati Children’s Molecular Genetics Laboratory, in conjunction with Jorge Bezerra, MD, and the Division of Gastroenterology, introduces new Liver Panels by Next-Generation Sequencing (NGS).

    The Heritable Liver Disease Genetic Testing program at Cincinnati Children’s originated with the development of the revolutionary JaundiceChip resequencing array. Now our program has broadened its scope with the advent of our new Liver Panels by Next-Generation Sequencing (NGS). The Liver Panels will meet your patients' specialized needs by offering a comprehensive genetic test menu for the diagnosis of an expansive range of heritable liver diseases.

    The Liver Panels are comprised of 22 clinically relevant genes related to heritable liver diseases. We have created six custom assays to correlate with your patients' unique clinical symptoms. The Liver Panels include the following genetic test options:

    Download: Liver Panels test spec sheet | Heritable Liver Disease test requisition  

    The Liver Panels use TruSeq Custom Amplicon (TSCA) capture and enrichment technology followed by next-generation sequencing to provide increased test sensitivity while maintaining the same rapid, comprehensive and cost effective analysis you have come to expect. Our team of pediatric gastroenterologists and molecular geneticists will review and interpret each customized analysis, giving you access to unparalleled clinical expertise.

    The Molecular Genetics Laboratory at Cincinnati Children's also offers single gene diagnostic testing and deletion / duplication analysis for the genes included in the Liver Panels. See a comprehensive list of tests offered.

    Why Choose Us?

    Our lab will give you access to unparalleled clinical expertise. Under the direction of Kejian Zhang, MD, MBA, we provide guidance in:

    • Clinical interpretation, recommendation for follow-up testing and medical management   
    • Genetic counseling
    • Coordination of studies for at-risk family members

    • Related Area

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      The Division of Gastroenterology, Hepatology and Nutrition at Cincinnati Children’s is a national and international referral destination.

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