• HLH patients.
  • Experts in Treating HLH

    Hemophagocytic lymphohistiocytosis (HLH) is a disorder of the immune system in which too many infection-fighting cells are produced and activated, causing damage to organs. While rare, HLH is rapidly fatal. However, with prompt and accurate diagnosis and timely treatment, a cure is possible. 

    Unfortunately, few physicians are knowledgeable about HLH, and it is often misdiagnosed or diagnosed too late. Without access to effective treatment, primarily bone marrow transplantation (BMT), most patients with HLH die. 

    As the most experienced facility in the nation in treating HLH, Cincinnati Children’s has assembled a team of researchers, physicians, families who have faced an HLH diagnosis and philanthropists to create the HLH Center of Excellence. 

    The center focuses on four core priorities: 

    While HLH is rare, Cincinnati Children’s treats a large population of children with HLH. The clinical and research pioneers at Cincinnati Children’s are committed to changing the outcome for children with HLH.

  • 700 Miles to Hope Bike Ride

    Support the riders.

    They ride to remember loved ones. They ride for survivors. They ride to honor children battling the life-threatening immune disorder HLH.  They ride to find a cure.  What started as just one dad has evolved into 20 cyclists riding from Natchez, Mississippi, to the doorstep of Cincinnati Children’s in a 700-mile, seven-day journey. 
    Learn more about this year’s bike ride and how you can help.

  • Donate to the HLH Center of Excellence at Cincinnati Children's.

    You are an important partner in the life-saving work of the HLH Center of Excellence.

    To learn more, contact:

    Donate to the HLH Center of Excellence at Cincinnati Children's.

    Beth Sims, Development Department
    Phone: 513-636-5285
    Email: beth.sims@cchmc.org