HLH Center of Excellence

  • HLH patients.
  • Experts in Treating HLH

    Hemophagocytic lymphohistiocytosis (HLH) is a disorder of the immune system in which too many infection-fighting cells are produced and activated, causing damage to organs. While rare, HLH is rapidly fatal. However, with prompt and accurate diagnosis and timely treatment, a cure is possible. 

    Unfortunately, few physicians are knowledgeable about HLH, and it is often misdiagnosed or diagnosed too late. Without access to effective treatment, primarily bone marrow transplantation (BMT), most patients with HLH die. 

    As the most experienced facility in the nation in treating HLH, Cincinnati Children’s has assembled a team of researchers, physicians, families who have faced an HLH diagnosis and philanthropists to create the HLH Center of Excellence. 

    The center focuses on four core priorities: 

    While HLH is rare, Cincinnati Children’s treats a large population of children with HLH. The clinical and research pioneers at Cincinnati Children’s are committed to changing the outcome for children with HLH.

  • 700 Miles to Hope − An HLH Journey | A Cincinnati Children’s Documentary

    One of the most difficult things in life is to watch someone you love suffer. When that loved one is a child, the pain is immeasurable. This is the story of families who have suffered greatly. Some have had to endure the loss of their children to the horrible immune disorder HLH. Some have children who have survived. One is a survivor himself. They come together on a journey of extreme determination, a little stronger and inspired.

 
  • Clinical Trial for HLH

    Cincinnati Children’s is conducting the only clinical trial approved by the National Institutes of Health for HLH treatment.
    > Learn more at the Cincinnati Children’s web page or at ClinicalTrials.gov, a service of the NIH.
  • Donate to the HLH Center of Excellence at Cincinnati Children's.

    You are an important partner in the life-saving work of the HLH Center of Excellence.

    To learn more, contact:

    Donate to the HLH Center of Excellence at Cincinnati Children's.

    Beth Sims, Development Department
    Phone: 513-636-5285
    Email: beth.sims@cchmc.org