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The Schubert-Martin Inflammatory Bowel Disease Center is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.
Lee A. Denson, MD Medical Director, Inflammatory Bowel Disease Center 513-636-7575 firstname.lastname@example.org
Medical Director, Inflammatory Bowel Disease Center
Professor, UC Department of Pediatrics
Inflammatory bowel disease; growth failure; celiac disease
The primary focus of Dr. Lee A. Denson's laboratory is to determine the molecular basis for alterations in growth hormone signaling in inflammatory bowel diseases (IBD).
Normal growth and development are dependent upon the ability of growth hormone to regulate IGF-1 expression. Evidence from studies in children with IBD and mouse models of colitis indicates that inflammatory cytokines which are up regulated in this setting may cause an acquired GH resistance. Consequences may include growth failure, altered body composition and impaired mucosal healing.
We are using complementary experimental and patient-based approaches to investigate regulation of growth hormone signaling in mouse models of colitis and in children with Crohn's disease. These include down regulation of the growth hormone receptor and up regulation of a family of post-receptor inhibitory proteins, the Suppressors of Cytokine Signaling (SOCS). These studies should lead to the development of more effective therapies for children with IBD and other chronic inflammatory conditions.
MD: Medical College of Virginia, Richmond, VA, 1993.
Residency: Yale-New Haven Hospital, New Haven, CT, 1993-96.
Certification: Pediatrics, 1996 and 2002.
Fellowship: Yale University School of Medicine, New Haven, CT, 1996-99.
Herzer M, Denson LA, Baldassano RN, Hommel KA. Family functioning and health-related quality of life in adolescents with pediatric inflammatory bowel disease. Eur J Gastroenterol Hepatol. 2011 Jan;23(1):95-100.
Gray WN, Denson LA, Baldassano RN, Hommel KA. Disease activity, behavioral dysfunction, and health-related quality of life in adolescents with inflammatory bowel disease. Inflamm Bowel Dis. 2010 Nov 4.
Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn's disease. J Laparoendosc Adv Surg Tech A. 2010 Nov;20(9):791-5.
Denson LA, Kim MO, Bezold R, Carey R, Osuntokun B, Nylund C, Willson T, Bonkowski E, Li D, Ballard E, Collins M, Moyer MS, Klein DJ. A randomized controlled trial of growth hormone in active pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2010 Aug;51(2):130-9.
Nylund CM, Denson LA, Noel JM. Bacterial enteritis as a risk factor for childhood intussusception: a retrospective cohort study. J Pediatr. 2010 May;156(5):761-5.
Ingerski LM, Baldassano RN, Denson LA, Hommel KA. Barriers to oral medication adherence for adolescents with inflammatory bowel disease. J Pediatr Psychol. 2010 Jul;35(6):683-91.
Tomer G, Wetzler G, Keddache M, Denson LA. Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients. J Pediatr Gastroenterol Nutr. 2009 May;48(5):531-7.
Uchida K, Nakata K, Suzuki T, Luisetti M, Watanabe M, Koch DE, Stevens CA, Beck DC, Denson LA, Carey BC, Keicho N, Krischer JP, Yamada Y, Trapnell BC. Granulocyte/macrophage-colony-stimulating factor autoantibodies and myeloid cell immune functions in healthy subjects. Blood. 2009 Mar 12;113(11):2547-56.
Han X, Uchida K, Jurickova I, Koch D, Willson T, Samson C, Bonkowski E, Trauernicht A, Kim MO, Tomer G, Dubinsky M, Plevy S, Kugathsan S, Trapnell BC, Denson LA. Granulocyte-macrophage colony-stimulating factor autoantibodies in murine ileitis and progressive ileal Crohn's disease. Gastroenterology. 2009 Apr;136(4):1261-71, e1-3.
Denson LA. Growth hormone therapy in children and adolescents: pharmacokinetic/pharmacodynamic considerations and emerging indications. Expert Opin Drug Metab Toxicol. 2008 Dec;4(12):1569-80. Review.
Dana (Chelly) Dykes, MD 513-803-1791 email@example.com
Assistant Professor, UC Department of Pediatrics
Pediatric inflammatory bowel disease
Dr. Dykes is working to develop a telemedicine program as an adjunct clinic model for patients with chronic medical conditions, particularly inflammatory bowel disease (IBD). Her work is aimed at improving healthcare related outcomes without increasing cost. She also participates in multi-center collaborative work aimed at reducing healthcare costs and improving outcomes for patients with IBD at a national level. She acts as a physician content expert for the development of innovated patient-centered tools and technology designed to help provide more personalized care for patients living with chronic medical conditions.
BS: Neuroscience and French, Vanderbilt University, Nashville, TN, 2002.
MD: University of Alabama School of Medicine, Birmingham, AL, 2006.
MS: Clinical and Translational Research, University of Cincinnati, Cincinnati, OH, 2012.
Residency: Pediatrics, Children’s Hospital at UAB, Birmingham, AL, 2009.
Fellowship: Pediatric Gastroenterology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2012.
Park KT, Crandall WV, Fridge J, Leibowitz IH, Tsou M, Dykes DM, Hoffenberg EJ, Kappelman MD, Colletti RB. Implementable Strategies and Exploratory Considerations to Reduce Costs Associated with Anti-TNF Therapy in Inflammatory Bowel Disease Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2014 May;20(5):946-51.
Dykes DM, Saeed SA. Imaging for inflammatory bowel disease: the new "sounding board". J Pediatr. 2013 Sep;163(3):625-6.
Dykes DM, Towbin AJ, Bonkowski E, Chalk C, Bezold R, Lake K, Kim MO, Heubi JE, Trapnell BC, Podberesky DJ, Denson LA. Increased Prevalence of Luminal Narrowing and Stricturing Identified by Enterography in Pediatric Crohn Disease Patients with Elevated Granulocyte-Macrophage Colony Stimulating Factor Auto-antibodies. Inflamm Bowel Dis. 2013 Sep;19(10):2146-54.
Phillip Minar, MD 513-636-4415 firstname.lastname@example.org
Pediatric gastroenterology; biomarkers of treatment response and disease severity in inflammatory bowel disease.
BA: Duquesne University, Pittsburgh, PA.
MD: Medical College of Wisconsin, Milwaukee, WI.
Residency: Pediatrics, Medical College of Wisconsin/Children's Hospital of Wisconsin, Milwaukee, WI.
Fellowship: Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Certification: General Pediatrics; Pediatric Gastroenterology.
Michael J. Rosen, MD, MSCI Attending Physician, Division of Gastroenterology, Hepatology and Nutrition 513-803-7044 email@example.com
Attending Physician, Division of Gastroenterology, Hepatology and Nutrition
Physician, Schubert-Martin Inflammatory Bowel Disease Center
Inflammatory bowel disease
Michael J. Rosen, MD, MSCI, focuses his career on the clinical care of children with inflammatory bowel disease (IBD), and to research aimed at better understanding the causes of chronic inflammation in childhood IBD. The primary focus of Dr. Rosen's laboratory is on the contribution of Type 2 (Th2) inflammation to pediatric colitis. Studies from Dr. Rosen’s lab have demonstrated increased mucosal activation of STAT6, a key Th2 cellular signaling protein, in children with ulcerative colitis and shown a role for STAT6 in perpetuating inflammation in a mouse model similar to ulcerative colitis.
Dr. Rosen is currently funded by the National Institutes of Health (NIH) to study the expression of genes related to Th2 inflammation in colon tissue form a large cohort of children with IBD. In addition, his laboratory is conducting ongoing studies with transgenic animal models to determine the mechanisms by which proteins important in perpetuating Th2 inflammatory responses contribute to inflammation in colitis.
Dr. Rosen serves on the National Pediatric Affairs Committee for the Crohn's & Colitis Foundation of America (CCFA). His a past recipient of the Fellow to Faculty Transition Award in IBD and the George Ferry Young Investigator Award from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN).
MD: Harvard Medical School, Boston, MA, 2003.
Residency: Boston Combined Residency Program in Pediatrics (Boston Children's Hospital and Boston Medical Center), Boston, MA, 2003-2006.
Fellowship: Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University Medical Center and the Monroe Carell, Jr. Children's Hospital at Vanderbilt, Nashville, TN, 2006-2009.
Masters of Science in Clinical Investigation (MSCI): Vanderbilt University School of Medicine, Nashville, TN, 2009.
Certification: Pediatrics, 2007; Pediatric Gastroenterology, Hepatology and Nutrition, 2009.
Lu N, Lieu L, Van Kaer L, Washington MK, Rosen MJ, Dubé P, Wilson KT, Ren X, Hao X Polk DB, Yan F. Activation of the EGFR in macrophages regulates cytokine production and experimental colitis. The Journal of Immunology. 2014; 192(3):1013-23.
Falaiye TO, Mitchell KR, Lu Z, Saville BR, Horst SN, Moulton DE, Schwartz DA, Wilson KT, Rosen MJ. Outcome following infliximab therapy for pediatric patients hospitalized with refractory colitis-predominant inflammatory bowel disease. Journal of Pediatric Gastroenterology and Nutrition. 2014; 58(2):213-9.
Rosen MJ*, Chaturvedi R, Washington MK, Kuhnhein LA, Moore PD, Coggeshall SS, McDonough EM, Weitkamp JH, Singh AB. Coburn LA, Williams CS, Van Kaer L, Peebles RS, Wilson KT. STAT6 activation intensifies disease severity while increasing expression of claudin-2 and Th2-inducing cytokines in murine oxazolone colitis. The Journal of Immunology. 2013; 190(4):1849-1858.
Weitkamp JH, Koyama T, Rock MT, Correa H, Goettel J Matta P, Oswald-Richter K, Rosen MJ, Engelhardt BG, Moore D, Polk DB. Diminished mucosal regulatory (FOXP3+) / effector (CD4+, CD8+) T cell ratios as evidence for disrupted immune regulation in necrotizing enterocolitis. Gut. 2013; 62(1):73-82.
Rosen MJ, Denson LA, Kugathasan S. Commentaries on "Workshop report: developing a pediatric inflammatory bowel diseases network and data platform in Canada": pediatric inflammatory bowel disease networks: raising the bar. Journal of Pediatric Gastroenterology and Nutrition. 2012 Aug;55(2):121-2.
Rosen MJ*, Frey MR, Washington MK, Chaturvedi R, Kuhnhein LA, Matta P, Revetta F, Wilson KT, Polk DB. STAT6 activation in ulcerative colitis: A new target for prevention of IL-13-induced colonic epithelial cell dysfunction. Inflammatory Bowel Diseases. 2011; 17(11):2224-2234.
Rosen MJ, Schwartz DA. 31 Year-old with Colitis and Perianal Disease. Clinical Gastroenterology and Hepatology. 2010;8(1):10-4.
Rosen MJ, Moulton DE, Koyama T, Morgan WM, Morrow SE, Herline AJ, Muldoon RL, Wise PE, Polk DB, Schwartz DA. Endoscopic Ultrasound to Guide the Combined Medical and Surgical Management of Pediatric Perianal Crohn’s Disease. Inflammatory Bowel Diseases. 2010; 16(3):461-8.
Forcione DG, Rosen MJ, Kisiel JB, Sands BE. Anti-Saccharomyces cerevisiae antibody (ASCA) positivity is associated with increased risk for early surgery in Crohn's disease. Gut. 2004;53:1117-1122.
Sands BE, Arsenault JE, Rosen MJ, et al. Risk of Early Surgery for Crohn's Disease: Implications for Early Treatment Strategies. American Journal of Gastroenterology. 2003;98(12):2712-2718.
Th2 Cytokines and Signaling in Pediatric Inflammatory Bowel Disease. Principal Investigator. National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases (NIH/NIDDK). Mar 2013-Mar 2018.
Myeloid Cell-Derived IL-33 in Chronic IL-10-Deficient Colitis. Principal Investigator. Cincinnati Children's Research Foundation. Jul 2014-Jun 2016.
Shehzad Ahmed Saeed, MD, FAAP, AGAF Clinical Director, Schubert–Martin Inflammatory Bowel Disease Center 513-803-3251 firstname.lastname@example.org
Clinical Director, Schubert–Martin Inflammatory Bowel Disease Center
Clinical Director, Division of Gastroenterology, Hepatology and Nutrition
Medical Director, Gi/Colorectal Inpatient Unit
Shehzad Saeed, MD, is interested in the epidemiology of pediatric inflammatory bowel disease (IBD). Specifically, he studies the genetic and phenotypic correlations as well as risk stratification for surgery in children with IBD. Additionally, Dr. Saeed is also involved in outcomes research of patients with IBD.
Dr. Saeed completed his medical education at Dow Medical College, University of Karachi, and then served his pediatric residency at University of Chicago Children’s Hospital. He then completed subspecialty training in pediatric gastroenterology at Floating Hospital for Children, New England Medical Center, and Tufts University, Boston. His focus of interest was inflammatory bowel diseases under the mentorship of Richard J Grand, MD. He has subsequently served as fellowship director and division director of the Division of Pediatric Gastroenterology and Nutrition Sciences at University of Alabama at Birmingham. He currently serves as the clinical director of the Schubert-Martin Pediatric IBD Center, and is associate professor of pediatrics at University of Cincinnati College of Medicine.
MD: Dow Medical College, University of Karachi, Pakistan.
Residencies: Pediatrics, Dow Medical College and Civil Hospital, Karachi, Pakistan; Pediatrics, University of Chicago Children’s Hospital (formerly known as Wyler Children’s Hospital).
Fellowship: Pediatric Gastroenterology and Nutrition, The Floating Hospital for Children, New England Medical Center, Tufts University.
Hocking MC, Barnes M, Shaw C, Lochman JE, Madan-Swain A, Saeed S. Executive function and attention regulation as predictors of coping success in youth with functional abdominal pain. J Pediatr Psychol. 2011 Jan;36(1):64-73.
Schaefer ME, Machan JT, Kawatu D, Langton CR, Markowitz J, Crandall W, Mack DR, Evans JS, Pfefferkorn MD, Griffiths AM, Otley AR, Bousvaros A, Kugathasan S, Rosh JR, Keljo DJ, Carvalho RS, Tomer G, Mamula P, Kay MH, Kerzner B, Oliva-Hemker M, Kappelman MD, Saeed SA, Hyams JS, Leleiko NS. Factors that determine risk for surgery in pediatric patients with Crohn's disease. Clin Gastroenterol Hepatol. 2010 Sep;8(9):789-94.
Malik TA, Saeed S. Autoimmune hepatitis: a review. J Pak Med Assoc. 2010 May;60(5):381-7.
Wallander JL, Madan-Swain A, Klapow J, Saeed S. A randomised controlled trial of written self-disclosure for functional recurrent abdominal pain in youth. Psychol Health. 2010 Apr 21:1-15.
Imielinski M, Baldassano RN, Griffiths A, et.al. Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet. 2009 Dec;41(12):1335-40.
Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, Crissinger KD, D'Amico MA, Day AS, Denson LA, Dubinsky M, Ebach DR, Hoffenberg EJ, Kader HA, Keljo DJ, Leibowitz IH, Mamula P, Pfefferkorn MD, Qureshi MA; Pediatric IBD Network for Research and Improvement. Variation in care in pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2009 Sep;49(3):297-303.
Maheshwari A, Kurundkar AR, Shaik SS, Kelly DR, Hartman Y, Zhang W, Dimmitt R, Saeed S, Randolph DA, Aprahamian C, Datta G, Ohls RK. Epithelial cells in fetal intestine produce chemerin to recruit macrophages. Am J Physiol Gastrointest Liver Physiol. 2009 Jul;297(1):G1-G10.
Donnithorne KJ, Atkinson TP, Hinze CH, Nogueira JB, Saeed SA, Askenazi DJ, Beukelman T, Cron RQ. Rituximab therapy for severe refractory chronic Henoch-Schönlein purpura. J Pediatr. 2009 Jul;155(1):136-9.
Haricharan RN, Proklova LV, Aprahamian CJ, Morgan TL, Harmon CM, Barnhart DC, Saeed SA. Laparoscopic cholecystectomy for biliary dyskinesia in children provides durable symptom relief. J Pediatr Surg. 2008 Jun;43(6):1060-4.
Britton LJ, Saeed SA. Abdominal pain in cystic fibrosis. J Pediatr Health Care. 2008 Nov-Dec;22(6):383-6.
Richard A. Falcone Jr., MD, MPH Director, Trauma Services 513-636-4371 email@example.com
Director, Trauma Services
Associate Professor, UC Department of Surgery
Pediatric injury prevention and outcomes; trauma education; management of colorectal disorders; inflammatory bowel disease; minimally invasive surgery; surgical oncology; extracorporeal life support (ECLS)
MPH: Harvard School of Public Health, Boston, MA, 2007.
MD: New York University School of Medicine, 1995.
General Surgery Residency: University of Cincinnati, 1995-2002.
Pediatric Surgery Fellowship: Cincinnati Children's Hospital Medical Center, 2002-2004.
Certification: Surgery, 2004; Pediatric Surgery, 2006.
Nance ML, Krummel TM, Oldham KT, Falcone R JR, Trauma Committee of the American Pediatric Surgical Association. Firearm injuries and Children: A Policy Statement of the American Pediatric Surgical Association. J Am Coll Surg. 2013 Nov; 217(5): 940-6.
Patterson M, Geis G, Falcone R, LeMaster T, Wears R. In situ simulation: detection of safety threats and teamwork training in a high risk emergency department. BMJ Qual Saf. 2013 Jun;22(6):468-77.
Jurickova I, Collins MH, Chalk C, Seese A, Bezold R, Lake K, von Allmen D, Frischer JS, Falcone RA, Trapnell BC, Denson LA. Paediatric Crohn disease patients with stricturing behaviour exhibit ileal granulocyte-macrophage colony-stimulating factor (GM-CSF) autoantibody production and reduced neutrophil bacterial killing and GM-CSF bioactivity. Clin Exp Immunol. 2013 Jun;172(3)455-65.
Beaudin M, Maugans T, St-Vil D, Falcone RA Jr. Inappropriate use of infant seating devices increases risks of injury. J Pediatr Surg. 2013 May;48(5):1071-6.
Cook R, Gillespie GL, Kronk, R, Daugherty M, Moody SM, Allen LJ, Shebesta KB, Falcone RA. Effect of an Educational Intervention on Nursing Staff Knowledge, Confidence, and Practice in the Care of Children with Mild Traumatic Brain Injury. J Neurosci Nurs. 2013 Apr;45(2):108-18.
Kelleher DC, Renaud EJ, Ehrlich PF, Burd RS; Pediatric Trauma Society Guidelines Committee. Guidelines for alcohol screening in adolescent trauma patients: a report from the Pediatric Trauma Society Guidelines Committee. J Trauma Acute Care Surg. 2013 Feb;74(2):671-82.
Daugherty MC, Mehlman CT, Moody S, LeMaster T, Falcone RA Jr . Significant rate of misuse of the Hare traction splint for children with femoral shaft fractures. J Emerg Nurs. 2013 Jan;39(1):97-103.
Chatoorgoon K, Brown RL, Garcia VF, Falcone RA. Role of computed tomography and clinical findings in pediatric blunt intestinal injury: a multi-center study. Pediatr Emerg Care. 2012 Dec;28(12):1338-42.
Beaudin M, Daugherty M, Geis G, Moody S, Brown RL, Garcia VF, Falcone RA Jr. Assessment of factors associated with the delayed transfer of pediatric trauma patients: an emergency physician survey. Pediatr Emerg Care. 2012 Aug;28(8):758-63.
Falcone RA Jr, Haas L, King E, Moody S, Crow J, Moss A, Gaines B, McKenna C, Gourlay DM, Werner C, Meagher DP Jr, Schwing L, Garcia N, Brown D, Groner JI, Haley K, Deross A, Cizmar L, Armola R. A multicenter prospective analysis of pediatric trauma activation criteria routinely used in addition to the six criteria of the American College of Surgeons. J Trauma Acute Care Surg. 2012 Aug;73(2):377-84.
Jason S. Frischer, MD Director, Peña Colorectal Center 513-636-3240 firstname.lastname@example.org
Director, Peña Colorectal Center
Director, Extracorporeal Membrane Oxygenation (ECMO) Program
Division of Pediatric General and Thoracic Surgery
Assistant Professor, UC Department of Surgery
Jason S. Frischer, MD, has been named the director of the Peña Colorectal Center at Cincinnati Children's Hospital Medical Center. He earned his medical degree at SUNY Downstate Medical Center. He obtained his medical degree at SUNY Downstate and went on to complete his general surgery and chief residency at the Mount Sinai School of Medicine in New York where he focused his training on inflammatory bowel disease. Additionally, he spent two years as the ECMO fellow and postdoctoral research fellow in angiogenesis at the Children's Hospital of New York, Columbia University. Dr. Frischer completed his pediatric surgery fellowship at the Children's Hospital of New York, Columbia University.
Dr. Frischer has a special interest in pediatric colorectal surgery including inflammatory bowel disease (IBD, Crohn's disease and ulcerative colitis), Hirschsprung’s disease anorectal malformations (ARM), fecal incontinence and constipation. He serves as the director of the ECMO program and is a member of the congenital diaphragmatic hernia (CDH) team. He is also a member of the Epidermolysis Bullosa (EB) Center. He has an interest in neonatal surgery and minimally invasive surgery.
Dr. Frischer is a member of Alpha Omega Alpha (national medical honor society) and was selected by Cincy Magazine Best Doctors from 2010 to 2013. He also was selected by Castle Connolly Medical Ltd. and U.S. News & World Report “Top Doctors” in 2012 and 2013.
BS: Cornell University, Ithaca, NY, 1995.
MD: SUNY Downstate Medical Center, Brooklyn, NY, 1999.
Residency: Mount Sinai School of Medicine, The Mount Sinai Hospital, New York, NY, 2000-2001 and 2003-2006.
ECMO/Research Fellowship: Children's Hospital of New York - Presbyterian, Columbia University, New York, NY, 2001-2003.
Pediatric Surgery Residency: Children's Hospital of New York – Presbyterian, Columbia University, New York, NY, 2006-2008.
Certification: General Surgery, 2007; Pediatric Surgery, 2010.
Chernoguz A, Crawford, K, Vandersall A, Willson T, Denson LA, Frischer JS. Pre-treatment with Anti-VEGF therapy may exacerbate inflammation in experimental acute colitis. J Pediatr Surg. 2012 Feb;47(2):347-54.
Le LD, Keswani SG, Biesiada J, Lim FY, Kingma PS, Haberman BE, Frischer J, Habli M, Crombleholme TM. The congenital diaphragmatic hernia composite prognostic index correlates with survival in left-sided congenital diaphragmatic hernia. J Pediatr Surg. 2012 Jan;47(1):57-62.
Lawal TA, Falcone RA, von Allmen D, Denson LA, Levitt MA, Warner BW, Frischer JS. The utility of routine pouchogram before ileostomy reversal in children and adolescents following ileal pouch anal anastomosis. J Pediatr Surg. 2011 Jun;46(6):1222-5.
Chernoguz A, Crawford KM, Donovan EC, Vandersall AE, Berglund C, Cripe TP, Frischer JS. EGFR Inhibition Fails to Suppress Vascular Proliferation and Tumor Growth in a Ewing’s Sarcoma Model. J Surg Res. 2012 Mar;173(1):1-9.
Lawal TA, Frischer JS, Falcone RA, Chatoorgoon K, Denson LA, Levitt MA. The transanal approach with laparoscopy or laparotomy for the treatment of rectal strictures in Crohn’s disease. J Laparoendosc Adv Surg Tech A. 2010 Nov;20(9):791-5.
Bischoff A, Gupta A, D’Mello S, Mezoff A, Podberesky D, Barnett S, Keswani S, Frischer JS. Crohn’s disease limited to the appendix: a case report in a pediatric patient. Pediatr Surg Int. 2010 Nov;26(11):1125-8.
Vuletin JF, Lim FY, Cnota J, Kline-Fath B, Salisbury S, Haberman B, Kingma P, Frischer JS, Crombleholme T. Prenatal pulmonary hypertension index: novel prenatal predictor of severe postnatal pulmonary artery hypertension in antenatally diagnosed congenital diaphragmatic hernia. J Pediatr Surg. 2010 Apr;45(4):703-8.
Frischer JS, Lee A, Serur A, Huang J, Bae JO, Kornfield ZN, Eljuga L, Shawber CJ, Feirt N, Mansukhani M, Stempak D, Baruchel S, Bender JG, Kandel JJ, Yamashiro DJ. Inhibition of cyclooxygenase-2 disrupts tumor vascular mural cell recruitment and survival signaling. Cancer Res. 2006 Apr;66(8):4378-84.
Frischer JS, Huang J, Serur A, Kadenhe-Chiweshe A, McCrudden KW, O’Toole K, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Effects of potent VEGF blockade on experimental Wilms tumor and its persisting vasculature. Int J Onc. 2004 Sep;25(3):549-53.
Huang J, Frischer JS, Serur A, Kadenhe A, Yokoi A, McCrudden KW, New T, O’Toole K, Zabski S, Rudge JS, Holash J, Yancopoulos GD, Yamashiro DJ, Kandel JJ. Regression of established tumors and metastases by potent vascular endothelial growth factor blockade. Proc Natl Acad Sci USA. 2003 June 24;100(13):7785-90.
Belinda Hsi Dickie, MD, PhD Pediatric Surgeon, Peña Colorectal Center 513-636 3240 email@example.com
Pediatric Surgeon, Peña Colorectal Center
Surgical Director, Hemangioma and Vascular Malformation Program
Phone 513-636 3240
Colorectal surgery; vascular malformations; minimally invasive surgery; general pediatric surgery.
Visit the Dickie Lab.
Belinda Hsi Dickie, MD, PhD, is the surgical director of the Hemangioma and Vascular Malformations Center since July 2013. She is also the director of the Vascular Anomalies Fellowship. Dr. Dickie is an assistant professor with the Division of Pediatric General and Thoracic Surgery at Cincinnati Children's Hospital Medical Center within the UC Department of Pediatrics. She obtained her medical degree at the University of Toronto, and completed general surgery residency and an advanced minimally invasive surgery fellowship at the University of Alberta. She continued her training, completing fellowships in pediatric vascular malformations and pediatric colorectal surgery at Cincinnati Children’s Hospital Medical Center and in pediatric surgery at the University of Florida. She returned to Cincinnati Children’s in 2011.
Dr. Dickie has a special interest in the medical and surgical treatment of vascular malformations, and minimally invasive surgery. She has a lab in vascular biology which looks at the genetics and molecular pathways involved with lymphangiogenesis, and the genetics involved in the development of vascular malformations. The lab is looking at novel mutations in vascular malformations and the potential effects on lymphatic growth, and different treatment alternatives.
MD: University of Toronto, Toronto,Ontario, Canada 1998.
Residency: General Surgery, University of Alberta, Edmonton, Alberta, Canada.
Fellowship: Advanced Minimally Invasive Surgery, University of Alberta, Edmonton, Alberta, Canada; Vascular anomalies, Cincinnati Children's, Cincinnati, OH; Pediatric Colorectal Surgery, Cincinnati Children's, Cincinnati, OH; Pediatric Surgery, University of Florida Gainesville, FL.
Certification: General Surgery, 2006; Pediatric Surgery, 2011.
Dickie BH, Webb KM, Eradi B, Levitt MA. The problematic Soave cuff in Hirschsprung disease: Manifestations and treatment. J Pediatr Surg. 2014 Jan;49(1):77-81.
Knod JL, Garrison AP, Frischer JS, Dickie B. Foregut duplication cyst associated with esophageal atresia and tracheoesophageal fistula: a case report and literature review. J Pediatr Surg. 2013 May;48(5):E5-7.
de Blaauw I, Midrio P, Breech L, Bischoff A, Dickie B, Versteegh HP, Peña A, Levitt MA. Treatment of adults with unrecognized or inadequately repaired anorectal malformations: 17 cases of rectovestibular and rectoperineal fistulas. J Pediatr Adolesc Gynecol. 2013 Jun;26(3):156-60.
Levitt MA, Dickie B, Peña A. The Hirschsprungs patient who is soiling after what was considered a "successful" pull-through. Semin Pediatr Surg. 2012 Nov;21(4):344-53.
Murrell Z, Dickie B, Dasgupta R. Lung nodules in pediatric oncology patients: a prediction rule for when to biopsy. J Pediatr Surg. 2011 May;46(5):833-7.
Cuenca AG, Reddy SV, Dickie B, Kays DW, Islam S. The usefulness of the upper gastrointestinal series in the pediatric patient before anti-reflux procedure or gastrostomy tube placement. J Surg Res. 2011 Oct;170(2):247-52.
Levitt MA, Dickie B, Peña A. Evaluation and treatment of the patient with Hirschsprung disease who is not doing well after a pull-through procedure. Semin Pediatr Surg. 2010 May;19(2):146-53.
Dickie B, Dasgupta R, Nair R, Alonso MH, Ryckman FC, Tiao GM, Adams DM, Azizkhan RG. Spectrum of hepatic hemangiomas: management and outcome. J Pediatr Surg. 2009 Jan;44(1):125-33.
Kneteman NM, Weiner AJ, O'Connell J, Collett M, Gao T, Aukerman L, Kovelsky R, Ni ZJ, Zhu Q, Hashash A, Kline J, Hsi B, Schiller D, Douglas D, Tyrrell DL, Mercer DF. Anti-HCV therapies in chimeric scid-Alb/uPA mice parallel outcomes in human clinical application. Hepatology. 2006 Jun;43(6):1346-53.
Hao C, Song JH, Hsi B, Lewis J, Song DK, Petruk KC, Tyrrell DL, Kneteman NM. TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice. Cancer Res. 2004 Dec 1;64(23):8502-6.
Daniel von Allmen, MD Surgeon-in-Chief; Lester W. Martin Chair of Pediatric Surgery 513-636-4371 firstname.lastname@example.org
Surgeon-in-Chief; Lester W. Martin Chair of Pediatric Surgery
Professor, UC Department of Surgery
Pediatric surgical oncology; pediatric inflammatory bowel disease; surgical innovation; surgical robotics
Daniel von Allmen, MD, came to Cincinnati from Chapel Hill, NC where he was the surgeon-in-chief and division chief at the North Carolina Children’s Hospital.
Dr. von Allmen completed his general surgery training at the University of Cincinnati and Cincinnati Children’s Hospital Medical Center. He is currently the treasurer of the American Pediatric Surgery Association. He also serves as the secretary treasurer of the Association of Pediatric Surgery Program Directors and is an active member of the Children’s Oncology Group.
Dr. von Allmen's special clinical interests include pediatric surgical oncology, pediatric inflammatory bowel disease, surgical innovation, and surgical robotics.
MD: University of Vermont, College of Medicine, Burlington, VT.
Residency: General Surgery, University of Cincinnati, Cincinnati, OH.
Fellowship: Pediatric Surgery, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH.
Certifications: General Surgery, Pediatric Surgery.
Mayer ML, Beil HA, von Allmen D. Distance to care and relative supply among pediatric surgical subspecialties. J Pediatr Surg. 2009;44:483-495.
Kevin A. Hommel, PhD Pediatric Psychologist, Research, Behavioral Medicine & Clinical Psychology 513-803-0407 email@example.com
Pediatric Psychologist, Research, Behavioral Medicine & Clinical Psychology
Director, Divisional Data Core
Center for Adherence and Self-Management
Associate Professor, UC Department of Pediatrics
Promotion of treatment adherence; self-management in pediatric chronic conditions
Dr. Hommel's research is currently funded by the National Institutes of Health: National Institute of Child Health and Human Development and National Institute of Diabetes and Digestive and Kidney Diseases. Many of his studies are focused on the use of technology to promote self-management across chronic conditions, developing, testing (via randomized controlled trial), and optimizing behavioral treatments for nonadherence in inflammatory bowel disease (IBD), and examining the effects of nonadherence on disease outcomes and health-related quality of life (HRQoL). He is a co-investigator on the PROTECT study, which is a multisite U01 study aimed at defining the rate of corticosteroid-free remission in pediatric patients with ulcerative colitis receiving standardized medical therapy.
Dr. Hommel came to Cincinnati Children's Hospital Medical Center in 2008 from the Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine. He continues to collaborate with investigators at the Children's Hospital of Philadelphia.
BA: University of Central Oklahoma, 1996.
MS: Oklahoma State University,1999.
PhD: Oklahoma State University, 2002.
Residency: Cincinnati Children's Hospital Medical Center, 2002.
Fellowship: Cincinnati Children's Hospital Medical Center, 2004.
Hommel KA, Gray WN, Hente E, Loreaux K, Ittenbach RF, Maddux M, Baldassano R, Sylvester F, Crandall W, Doarn C, Heyman MB, Keljo D, Denson LA. The Telehealth Enhancement of Adherence to Medication in Pediatric IBD (TEAM) Trial: Design and Methodology. Contemporary Clinical Trials. 2015.
Hommel, KA, Modi AC, Piazza-Waggoner C, Myers JD. Translating Translational Research in Behavioral Science. Journal of Pediatric Psychology. 2015.
Gray WN, Resmini AR, Baker KD, Holbrook E, Morgan PJ, Ryan J, Saeed SA, Denson LA, Hommel KA. Concerns, Barriers, and Recommendations to Improve Transition from Pediatric to Adult IBD Care: Perspectives of Patients, Parents, and Health Professionals. Inflammatory Bowel Diseases. 2015.
Martin LJ, Franciosi JP, Collins MH, Abonia JP, Lee JJ, Hommel KA, Varni JW, Grotjan JT, Eby M, He H, Marsolo K, Putnam PE, Garza JM, Kaul A, Wen T, Rothenberg ME. Pediatric Eosinophilic Esophagitis Symptom Scores (PEESS® v2.0) associate with clinical, histologic, and molecular features. Journal of Allergy and Clinical Immunology. 2015.
Gray WN, Holbrook E, Morgan PJ, Saeed SA, Denson LA, Hommel KA. Transition readiness skills acquisition in adolescents and young adults with IBD: Findings from integrating assessment into clinical practice. Inflammatory Bowel Diseases. 2015.
Gray WN, Boyle SL, Graef DM, Janicke DM, Jolley CD, Denson LA, Baldassano RN, Hommel KA. Health-related quality of life in youth with Crohn’s disease: The role of disease activity and parenting stress. Journal of Pediatric Gastroenterology & Nutrition. 2015.
McMullen CK, Safford MM, Bosworth HB, Phansalkar S, Leong A, Fagan MB, Trontell A, Rumptz M, Vandermeer ML, The Centers for Education and Research on Therapeutics (CERTs) Patient-Centered Medication Management (PCMM) Workshop Working Group, Brinkman WB, Burkholder R, Frank L, Hommel K, Mathews R, Hornbrook MC, Seid M, Fordis M, Lambert B, McElwee N, Singh JA. Patient-centered priorities for improving medication management and adherence. Patient Education and Counseling. 2015;98:102-110.
Kuntz JL, Safford MM, Singh JA, Phansalkar S, Slight SP, Her QL, Lapointe NA, Mathews R, O’Brien E, Brinkman WB, Hommel K, Farmer KC, Klinger E, Maniam N, Sobko HJ, Bailey SC, Cho I, Rumptz MH, Vandermeer ML, Hornbrook MC. Patient-centered interventions to improve medication management and adherence: A qualitative review of research findings. Patient Education and Counseling. 2014;97(3):310-326.
Guilfoyle SM, Gray WN, Maddux MH, Hommel KA. Parenting Stress Predicts Depressive Symptoms in Adolescents with Inflammatory Bowel Disease. European Journal of Gastroenterology and Hepatology. 2014;26(9):964-71.
Ramsey RR, Ryan JL, Hershey AD, Powers SW, Aylward BS, Hommel KA. Treatment adherence in patients with headache: A systematic review. Headache. 2014;54(5):795-816.
Self-Management Assistance for Recommended Treatment (SMART) Portal Principal Investigator. National Institutes of Health/National Institute of Child Health and Human Development. 2013-2015
Enhancing Treatment Adherence and Health Outcomes. Principal Investigator. National Institutes of Health/National Institute of Child Health and Human Development. 2012-2017.
Telehealth Enhancement of Adherence to Medication in Pediatric IBD (TEAM Study). Principal Investigator. National Institutes of Health / National Institute of Child Health and Human Development. 2011-2016.
Predicting Response to Standard Pediatric Colitis Therapy: The PROTECT study. Co-Investigator. National Institute of Diabetes and Digestive and Kidney Diseases. 2012-2017.
Michael W. Mellon, PhD, ABPP Pediatric Psychologist, Clinical, Behavioral Medicine & Clinical Psychology 513-636-4336 firstname.lastname@example.org
Pediatric Psychologist, Clinical, Behavioral Medicine & Clinical Psychology
Acceptance and Commitment Therapy (ACT) application to children with IBD and their families
Michael W. Mellon, PhD, earned his PhD from the University of Memphis and completed an internship at the University of Mississippi Medical Center. Dr. Mellon is currently a pediatric psychologist in the Department of Pediatrics at Cincinnati Children’s Hospital Medical Center providing psychological care to patients with inflammatory bowel disease (IBD).
Dr. Mellon has also worked in the Department of Psychiatry and Psychology at the Mayo Clinic as the co-director of the Mayo Clinic-Dana Child Development and Learning Disorders Program, and director of the Enuresis and Encopresis Clinic. Dr. Mellon has published and presented papers at national conferences in the areas of behavioral treatments for enuresis and encopresis.
Recent research activities include a study of the relationship between ADHD and elimination disorders, and a study identifying predictors of outcome in conditioning treatment of primary nocturnal enuresis.
PhD: University of Memphis, Memphis, TN, 1993.
Residency: University of Mississippi Medical Center, Jackson, MS, 1992.
Certification: American Board of Professional Psychology, Child and Adolescent Clinical Psychology, 2009.
Homan KJ, Mellon MW, Houlihan D, Katusic MZ. Brief Report: Childhood Disintegrative Disorder: A Brief Examination of Eight Case Studies. J Autism Dev Disord. 2011 Apr;41(4):497-504.
Voigt RG, Johnson SK, Mellon MW, Hashikawa AH, Campeau LJ, Williams AR, Yawn BP, Juhn YJ. Relationship between parenting stress and concerns identified by developmental screening and their effects on parental medical care-seeking behavior. Clin Pediatr (Phila). 2009 May;48(4):362-8.
Voigt RG, Johnson SK, Hashikawa AH, Mellon MW, Campeau LJ, Williams AR, Yawn BP, Juhn YJ. Why parents seek medical evaluations for their children with mild acute illnesses. Clin Pediatr (Phila). 2008 Apr;47(3):244-51.
Mellon MW, Whiteside SP, Friedrich WN. The relevance of fecal soiling as an indicator of child sexual abuse: a preliminary analysis. J Dev Behav Pediatr. 2006 Feb;27(1):25-32.
Lynn SG, Bauch CD, Williams DE, Beatty CW, Mellon MW, Weaver AL. Psychologic profile of tinnitus patients using the SCL-90-R and Tinnitus Handicap Inventory. Otol Neurotol. 2003 Nov;24(6):878-81.
Bauch CD, Lynn SG, Williams DE, Mellon MW, Weaver AL. Tinnitus impact: three different measurement tools. J Am Acad Audiol. 2003 May-Jun;14(4):181-7.
McGrath ML, Mellon MW, Murphy L. Empirically supported treatments in pediatric psychology: constipation and encopresis. J Pediatr Psychol. 2000 Jun;25(4):225-54; discussion 255-6. Review.
Mellon MW, McGrath ML. Empirically supported treatments in pediatric psychology: nocturnal enuresis. J Pediatr Psychol. 2000 Jun;25(4):193-214; discussion 215-8, 219-24. Review.
Stern HP, Stroh SE, Fiedorek SC, Kelleher K, Mellon MW, Pope SK, Rayford PL. Increased plasma levels of pancreatic polypeptide and decreased plasma levels of motilin in encopretic children. Pediatrics. 1995 Jul;96(1 Pt 1):111-7.
Stern HP, Mellon MW, Stern TP, Fiser R. Information highway travelling back to our roots. J Ark Med Soc. 1994 Dec;91(7):316-7.
Kenneth R. Goldschneider, MD, FAAP Director, Pain Management Center 513-636-7768 email@example.com
Director, Pain Management Center
Professor, UC Department of Anesthesiology
Complex chronic pain conditions in infants, children and young adults, including those related to vascular malformations, epidermolysis bullosa and cancer.
MD: University of Connecticut Health Center School of Medicine, Farmington, CT, 1991.
Residency: Pediatrics, Duke University Medical Center, Durham, NC, 1991 - 1994; Anesthesiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 1994-1997.
Fellowship: Pediatric Anesthesia, Children's Hospital of Pittsburgh, Pittsburgh, PA, 1997 - 1998; Pain Management, Longwood Combined Pain Fellowship, The Children's Hospital, Boston, MA, 1998-1999.
Certification: American Board of Pediatrics, 1994; American Board of Anesthesiology, 1998; ABA Pain Management, 2000.
Lynch-Jordan AM, Kashikar-Zuck S, Goldschneider KR. Parent perceptions of adolescent pain expression: the adolescent pain behavior questionnaire. Pain. 2010 Dec;151(3):834-42.
Goldschneider K, Lucky AW, Mellerio JE, Palisson F, del Carmen Viñuela Miranda M, Azizkhan RG. Perioperative care of patients with epidermolysis bullosa: proceedings of the 5th international symposium on epidermolysis bullosa, Santiago Chile, December 4-6, 2008. Paediatr Anaesth. 2010 Sep;20(9):797-804.
Goldschneider KR, Lucky AW. Pain management in epidermolysis bullosa. Dermatol Clin. 2010 Apr;28(2):273-82, ix. Review.
Meyer MJ, Goldschneider KR, Bielefeldt K, Zeltzer L, Lackner J, Keefer L. Functional abdominal pain in adolescence: a biopsychosocial phenomenon. J Pain. 2008 Nov;9(11):984-90.
Hosu L, Meyer MJ, Goldschneider KR. Cerebrospinal fluid cutaneous fistula after epidural analgesia in a child. Reg Anesth Pain Med. 2008 Jan-Feb;33(1):74-6.
Goldschneider KR, Racadio JM, Weidner NJ. Celiac plexus blockade in children using a three-dimensional fluoroscopic reconstruction technique: case reports. Reg Anesth Pain Med. 2007 Nov-Dec;32(6):510-5.
Lynch AM, Kashikar-Zuck S, Goldschneider KR, Jones BA. Sex and age differences in coping styles among children with chronic pain. J Pain Symptom Manage. 2007 Feb;33(2):208-16.
Lynch AM, Kashikar-Zuck S, Goldschneider KR, Jones BA. Psychosocial risks for disability in children with chronic back pain. J Pain. 2006 Apr;7(4):244-51.
Kashikar-Zuck S, Vaught MH, Goldschneider KR, Graham TB, Miller JC. Depression, coping, and functional disability in juvenile primary fibromyalgia syndrome. J Pain. 2002 Oct;3(5):412-9.
Kashikar-Zuck S, Goldschneider KR, Powers SW, Vaught MH, Hershey AD. Depression and functional disability in chronic pediatric pain. Clin J Pain. 2001 Dec;17(4):341-9.
Alexandra Szabova, MD Director, Pain Management Fellowship 513-636-7768 firstname.lastname@example.org
Director, Pain Management Fellowship
Assistant Professor, UC Department of Anesthesiology
Chronic pediatric pain management; chronic pediatric and adolescent back and musculoskeletal pain management; acute pain management; pediatric regional anesthesia techniques; interventional pain management; pediatric anesthesia
Alexandra Szabova, MD, joined the staff of Cincinnati Children's Hospital Medical Center in 2006. She has worked as a pediatric anesthesiologist but also became a team member of the multidisciplinary chronic pediatric pain clinic.
Dr. Szabova demonstrated strong interest in pediatric chronic pain management during her training. She graduated from a combined pediatric and adult chronic pain management fellowship which was a result of close collaboration between the Cincinnati Children's and Cleveland Clinic Foundation, Cleveland, OH.
Dr. Szabova received her medical degree from the Comenius University in Bratislava, Slovakia, and completed her residency in anesthesia at the Cleveland Clinic Foundation, Cleveland, OH.
Dr. Szabova completed her combined pediatric and adult chronic pain management at Cincinnati Children's and Cleveland Clinic Foundation where is served as a chief fellow. She graduated with The Pain Fellow of the Year Award. Dr. Szabova completed pediatric anesthesia fellowship at the Cincinnati Children's.
Dr. Szabova's interests include chronic pediatric pain management, musculoskeletal pain in children and adolescents, acute pain management of surgical and non surgical pediatric patients, regional nerve blocks, and pediatric anesthesia.
MD: Comenius University, Bratislava, Slovakia, 1995.
Residency: Anesthesiology, Cleveland Clinic Foundation, Cleveland, OH.
Fellowship: Pain Management, Cleveland Clinic Foundation, Cleveland, OH; Pediatric Anesthesia, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Certification: Anesthesiology, 2005; ABA Pain Medicine, 2005.
Erin A. Holbrook, MSW, LISW
Social Worker II, Division of Social Services 513-803-2558 email@example.com
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