Infectious Diseases

  • Meet the Team

    Division of Infectious Diseases is home to specialists with a wide variety of backgrounds and areas of focus. As a team, this diversity makes us better prepared to care for your child’s unique needs. Learn more about our faculty and staff.

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    Division Head

    A photo of Robert W. Frenck Jr.

    Robert W. Frenck Jr., MD
    Interim Director, Division of Infectious Diseases

    513-803-3164

    robert.frenck@cchmc.org

    Robert W. Frenck Jr., MD

    Interim Director, Division of Infectious Diseases

    Medical Director, Division of Infectious Diseases

    Professor, UC Department of Pediatrics

    Phone: 513-803-3164

    Fax: 513-636-3959

    Email: robert.frenck@cchmc.org

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    Specialties

    Clinical

    Vaccine research; enteric diseases; travel medicine

    Research

    Enteric diseases; vaccinology

    Biography

    Robert W. Frenck Jr., MD, received his undergraduate degree from the University of California at San Diego in 1977 followed by his doctor of medicine degree from the University of Texas Health Science Center at Houston in 1981. He trained at the National Naval Medical Center in Bethesda, Maryland, completing his pediatric residency in 1984. After three years as a general pediatrician at the US Naval Hospital, Japan, he entered pediatric infectious disease fellowship training at the University of Texas Health Science Center at Houston, which he completed in 1990. Dr. Frenck is board-certified in both pediatrics and infectious diseases.

    Dr. Frenck's research interests include therapeutic and vaccine clinical trials with special interest in enteric diseases. After completing a 25-year career in the Navy, Dr. Frenck joined the UCLA Center for Vaccine Research in 2004 and served until 2006 as director of the Center and a Professor of Pediatrics at UCLA School of Medicine. Dr. Frenck has been active in the American Academy of Pediatrics and currently serves on the Red Book Committee. He is an acknowledged authority in infectious diseases and has authored over 60 articles and book chapters on various aspects of this subject.

    Education and Training

    BA: University of California at San Diego, San Diego, CA, 1977. 

    MD: University of Texas Medical School at Houston, Houston, TX, 1981. 

    Internship and Residency: US Naval Hospital, Bethesda, MD, 1981-1984. 

    Fellowship: Pediatric Infectious Diseases, University of Texas Medical School at Houston, Houston, TX, 1987-1990.

    Publications

    View PubMed Publications

    Faculty

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    Rebecca C. Brady, MD
    Director, Adult Clinical Services

    513-636-4578

    rebecca.brady@cchmc.org

    No photo available

    Rebecca C. Brady, MD

    Director, Adult Clinical Services

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: rebecca.brady@cchmc.org

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    Specialties

    Clinical Interests

    Adult and pediatric infectious disease

    Research Interests

    Cytomegalovirus and other viral infections 

    Education and Training

    MD: University of Kentucky, Lexington, KY, 1988.

    Residency: Internal Medicine/Pediatrics, University of Louisville, Louisville, KY.

    Fellowships: Pediatric Infectious Diseases, Children's Hospital Medical Center, Cincinnati, Ohio; Adult Infectious Diseases, University of Cincinnati, Cincinnati, OH.

    Certifications: Pediatrics, 1992, recertified 1999; Internal Medicine, 1993; Pediatric Infectious Diseases, 1997; Adult Infectious Diseases, 1997.

    Publications

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    Rhonda Cardin, PhD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-2420

    Email: rhonda.cardin@cchmc.org

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    Specialties

    The research focus of the Cardin lab is to understand the virus-host interactions that are important for CMV pathogenesis and immunological control of long term latent CMV infection. CMV encodes viral homologs to host proteins (such as IL-10, TNF, chemokine receptors) that interfere with the host immune response by immune evasion or by mimicry. Understanding the advantages provided by 'hijacking' of host proteins by CMV will lead to the development of effective vaccine strategies.

    Education and Training

    BA: Biology and Psychology, Washington University, St. Louis, Missouri, 1983.

    PhD: Microbiology, Louisiana State University, Baton Rouge, Louisiana, 1989.

    Publications

    View PubMed Publications

    A photo of Beverly Connelly.

    Beverly L. Connelly, MD
    Director, Infection Control Program

    513-636-8492

    beverly.connelly@cchmc.org

    Beverly L. Connelly, MD

    Director, Infection Control Program

    Professor, UC Department of Pediatrics

    Phone: 513-636-8492

    Fax: 513-636-7598

    Email: beverly.connelly@cchmc.org

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    Specialties

    Education and Training

    MD: Medical College of Georgia, Augusta, Ga., 1979.

    Residency: Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio, 1979-1982.

    Fellowship: Pediatric Infectious Disease, Children's Hospital Medical Center, Cincinnati, Ohio, 1983-1986.

    Certification: Pediatrics, 1984; Pediatric Infectious Diseases, 1994, recertified, 2000.

    Lara A. Danziger-Isakov, MD, MPH

    Director, Transplant ID

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: lara.danziger-isakov@cchmc.org

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    Specialties

    Transplant infectious diseases

    Biography

    Dr. Danziger-Isakov began her research career investigating cytomegalovirus in pediatric lung transplant recipients. After completing fellowship she led an international epidemiological study of pediatric lung transplant recipients including 14 international sites from North America and Europe to publish seminal manuscripts on fungal and viral infections through the International Pediatric Lung Transplant Collaborative. While at the Cleveland Clinic she performed an innovative investigation evaluating alloreactive cellular and humoral responses to influenza vaccine in transplant recipients. She is the protocol chair for two NIH-funded pediatric transplant studies in the Clinical Trials in Organ Transplantation in Pediatrics (CTOT-C) entitled "Viral Triggers of Alloimmunity and Autoimmunity in Pediatric Lung Transplantation (CTOTC-03)" and "Perceived Barriers to Patient Adherence after Pediatric Solid Organ Transplantation (CTOTC-05)" with principal investigator Stuart Sweet at Washington University. 

    Dr. Danziger-Isakov is a member of several international organizations, with guest lectureships throughout the North America and Europe. She has been recognized with the Clinical Science Career Development Award from the American Society of Transplantation in 2012, has been elected as co-editor for the American Society of Transplantation’s 3rd Edition of the Infectious Diseases Guidelines, and served as Infectious Disease Council Chair for the International Society of Heart and Lung Transplantation.

    Education and Training

    MD: Case Western Reserve University, Cleveland, OH, 1997.

    MPH: Saint Louis University, St. Louis, MO, 2004.

    Residency: Pediatrics, Cleveland Clinic Foundation, Cleveland, OH, 1997-2000.

    Fellowship: Pediatric Infectious Diseases, St. Louis Children’s Hospital, Washington Univeristy, St. Louis, MO, 2000-2003.

    Certification: Pediatrics, 2000; Pediatric Infectious Diseases, 2003.

    Publications

    View PubMed Publications

    David M. Hartley, PhD, MPH

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7278

    Email: david.hartley@cchmc.org

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    Specialties

    Research

    Infectious disease epidemiology; public health surveillance; mathematical and computer modeling

    Biography

    David M. Hartley, PhD, MPH, is associate professor of pediatrics at the James M. Anderson Center for Health Systems Excellence. His work investigates the factors governing the emergence and transmission of infectious diseases by applying mathematical modeling, computer simulation, and data analytic approaches. Additionally, he is interested in applying information technology and mathematical methods to better understand and improve patient safety and communications in healthcare settings. He obtained his PhD degree in physics from the University of Maryland Baltimore County in 1996 and his MPH degree with an emphasis in epidemiology and biostatistics from the George Washington University in 2006. Dr. Hartley has served on numerous review, advisory, and expert panels, including a White House Blue Ribbon Panel charged with addressing the threat of bioterrorism directed against livestock (2003) and the DHS-NIH Research and Policy for Infectious Disease Dynamics (RAPIDD) working group (2008-2014). He has held faculty positions at the University of Maryland School of Medicine (2003-2007) and the Georgetown University School of Medicine (2007-2014).

    Education and Training

    PhD: University of Maryland Baltimore County, Baltimore, MD, 1996.

    MPH: George Washington University, Washington, DC, 2006.

    Publications

    View PubMed Publications
    A photo of David Haslam.

    David B. Haslam, MD
    Director, Antimicrobial Stewardship Program

    513-803-1170

    david.haslam@cchmc.org

    David B. Haslam, MD

    Director, Antimicrobial Stewardship Program

    Clinical Director, Division of Infectious Diseases

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-1170

    Email: david.haslam@cchmc.org

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    Specialties

    Pediatric infectious diseases; host-microbial interactions; innate immunity

    Education and Training

    MD: University of Calgary, Calgary, Alberta, 1987.

    Rotating Internship: McGill University, Montreal, Quebec, 1988.

    Residency: University of Ottawa, Ottawa, Quebec, 1991.

    Fellowship: Washington University School of Medicine, St. Louis, MO, 2005.

    Certification: Pediatric Infectious Diseases, 1997.

    Publications

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    Andrew B. Herr, PhD

    Associate Professor, UC Department of Pediatrics

    Phone: 513-803-7490

    Email: andrew.herr@cchmc.org

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    Specialties

    Research

    Structural biology and biophysics of antibodies; immune receptors; bacterial surface proteins

    Biography

    Andrew Herr, PhD, is an associate professor in the Division of Immunobiology and Center for Systems Immunology, with an affiliate appointment in the Division of Infectious Diseases. Dr. Herr completed his thesis work in molecular biophysics from Washington University in St. Louis, and completed his postdoctoral work in structural immunology at the California Institute of Technology as a Damon Runyon Research Fellow. He was recruited to the University of Cincinnati College of Medicine as an Ohio Eminent Scholar in Structural Biology before moving to Cincinnati Children’s Hospital.

    Dr. Herr solved the first structure of a human IgA1 antibody bound to its cognate Fc receptor while at Caltech, and his lab has continued to study antibodies and immune receptors implicated in autoimmune diseases. In addition, the lab is studying a family of related collagen-specific immune receptors such as glycoprotein VI, which activates platelets upon exposure to fibrous collagen. The Herr lab also studies mechanisms of bacterial pathogenesis. Specifically, they discovered the zinc-dependent mechanism of intercellular adhesion in bacterial biofilms formed by Staphylococcus epidermidis and S. aureus. Biofilms are specialized bacterial colonies that are highly resistant to antibiotics and immune responses, so developing novel therapies to prevent biofilm formation is of high importance.

    Before joining the faculty at Cincinnati Children’s, Dr. Herr was an Ohio Eminent Scholar in Structural Biology at the University of Cincinnati College of Medicine and served as an associate director of the Cincinnati Medical Scientist (MD/PhD) Training Program. Dr. Herr received the 2014 Emerging Entrepreneurial Achievement Faculty Award from UC for his work to commercialize a novel anti-infective therapy based on his lab’s research.

    Education and Training

    BA: Oral Roberts University, Tulsa, OK, 1993.

    PhD: Washington University Medical School, St. Louis, MO, 1999.

    Postdoc: California Institute of Technology, Pasadena, CA, 2003.

    Publications

    View PubMed Publications

    Grants

    Studies of metal-dependent intercellular adhesion in Staphylococcal biofilms. Principal Investigator. National Institutes of Health. Sep 2011 – Jun 2015. NIH R01 GM094363.

    Analytical tools for the analysis of clustered O-glycans in clinical samples. Principal Investigator of Sub-contract. National Institutes of Health. Sep 2011 – Jul 2015. NIH R01 GM098539.

    A photo of Margaret Hostetter.

    Margaret K. Hostetter, MD
    BK Rachford Professor and Chair, Department of Pediatrics

    513-636-4509

    margaret.hostetter@cchmc.org

    Margaret K. Hostetter, MD

    BK Rachford Professor and Chair, Department of Pediatrics

    Professor, UC Department of Pediatrics

    Phone: 513-636-4509

    Email: margaret.hostetter@cchmc.org

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    Specialties

    Bacterial and fungal infections; medical evaluation of internationally adopted children

    Education and Training

    MD: Baylor College of Medicine.

    Residency: Boston Children’s Hospital.

    Training Fellowship: Boston Children’s Hospital.

    Board Certification: Pediatrics; Pediatric Infectious Diseases.

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    Grant C. Paulsen, MD

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-636-4578

    Email: grant.paulsen@cchmc.org

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    Specialties

    Clinical

    Transplant infectious diseases

    Biography

    Dr. Paulsen began his research career investigating Epstein-Barr Virus (EBV) and its impact on the immune system of pediatric renal transplant recipients as well as analysis of risk factors for EBV viremia after renal transplantation. These results were presented at the World Tranplant Congress 2014 with the full manuscript in process.

    Education and Training

    MD: University of Colorado Health Sciences Center, Denver, CO, 2005.

    Residency: Internal Medicine and Pediatrics, University of North Carolina, Chapel Hill, NC, 2005-2009.

    Fellowship: Adult and Pediatric Infectious Diseases, University of Alabama, Birmingham, AL 2010-2014.

    Certification: Internal Medicine, 2009; Pediatrics, 2010.

    Publications

    Elizabeth P. Schlaudecker, MD, MPH

    Assistant Professor, UC Department of Pediatrics

    Phone: 513-803-5187

    Email: elizabeth.schlaudecker@cchmc.org

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    Specialties

    Global health; influenza; prevention of infant infection with maternal immunization

    Biography

    Elizabeth P. Schlaudecker, MD, MPH, is a faculty member in the Division of Infectious Diseases and the Global Health Center. Dr. Schlaudecker received her medical degree and master's in public health from the University of Cincinnati and completed a pediatrics residency and chief residency at Cincinnati Children's.

    Dr. Schlaudecker was awarded a Fogarty International Clinical Research Fellowship from the National Institutes of Health in 2009, and she investigated the etiology and seasonality of viral respiratory disease in Honduran children under the age of five. She was awarded the Pediatric Infectious Diseases Society Blue Ribbon Research award in 2011 for similar work in Bangladesh. After joining the faculty of Cincinnati Children's in 2011, she continued her influenza research with a Procter Scholars award. Dr. Schlaudecker has traveled to Honduras, the Dominican Republic, Costa Rica, Ecuador, Kenya, South Africa, and Cameroon as part of her clinical and research training.

    Education and Training

    MD: University of Cincinnati, Cincinnati, OH, 2003.

    Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2006.

    Chief Residency: Pediatrics, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2007.

    Fellowship: Infectious Diseases, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2011.

    MPH: Public Health, University of Cincinnati, Cincinnati, OH, 2011.

    Certification: Pediatrics, 2006.

    Publications

    View PubMed Publications

    Grants

    Comparison of Immunological Responses to Influenza Infection and Immunization in Pregnant and Non-Pregnant Women. Principal Investigator. Cincinnati Children’s Hospital Medical Center. 2011 - 2013.

    A photo of Dr. Samir Shah.

    Samir S. Shah, MD, MSCE
    Director, Division of Hospital Medicine

    513-636-6222

    samir.shah@cchmc.org

    Samir S. Shah, MD, MSCE

    Director, Division of Hospital Medicine

    Attending Physician, Division of Hospital Medicine

    Professor, UC Department of Pediatrics

    Phone: 513-636-6222

    Email: samir.shah@cchmc.org

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    Specialties

    Pediatric infectious diseases; pediatric hospital medicine; community-acquired pneumonia; bacterial meningitis; observational study designs; administrative data sources

    Biography

    Samir S. Shah, MD, MSCE, is a pediatric infectious diseases and pediatric hospital medicine physician whose research focuses on improving the efficiency and quality of care of children hospitalized with common, serious infections such as pneumonia and meningitis. Ongoing projects include studying the comparative effectiveness of different antibiotics in the treatment of community-acquired pneumonia and developing novel databases to conduct comparative effectiveness research.

    Dr. Shah is currently the associate chair of the National Pneumonia Guidelines Committee, jointly sponsored by the Infectious Diseases Society of America and the Pediatric Infectious Diseases Society. He is also an executive council member of the Pediatric Research in Inpatient Settings (PRIS) Network.

    Dr. Shah is an associate editor of the Journal of Hospital Medicine, the official journal of the Society of Hospital Medicine. He also serves on the editorial boards of Archives of Pediatrics & Adolescent Medicine and Infection Control & Hospital Epidemiology. In addition, he is editor or co-editor of 7 books in the fields of Pediatrics and Infectious Diseases including The Philadelphia Guide: Inpatient Pediatrics (Lippincott Williams & Wilkins), and Pediatric Practice: Infectious Diseases (McGraw-Hill Medical), an infectious diseases textbook written for the pediatric generalist.

    Dr. Shah has received several prestigious research awards, including the Society of Hospital Medicine Excellence in Research Award, the Pediatric Infectious Diseases Society Burtis Burr Breese Award, and the Pediatric Infectious Diseases Society Young Investigator Award.

    Education and Training

    BA: University of Pennsylvania, Philadelphia, PA, 1993.

    MD: Yale University School of Medicine, New Haven, CT, 1998.

    Residency: Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 2001.

    Fellowship: Pediatric Infectious Diseases, The Children’s Hospital of Philadelphia, Philadelphia, PA, 2005; Academic General Pediatrics, The Children’s Hospital of Philadelphia, Philadelphia, PA, 2005.

    MSCE: University of Pennsylvania School of Medicine, Philadelphia, PA, 2007.

    Certification: Pediatrics, 2001, 2008; Pediatric Infectious Diseases, 2005.

    Publications

    View PubMed Publications

    Grants

    Predicting adverse outcomes in childhood pneumonia. Principal Investigator. Robert Wood Johnson Foundation. Jul 2008 - Dec 2011.

    PHIS+: augmenting the pediatric health information system with clinical data. Site Principal Investigator. Agency for Healthcare Research and Quality. Sep 2010 - Sep 2013. #R01 HS019862
    .
    Pediatric research in inpatient settings: research prioritization for pediatric hospital medicine. Site Principal Investigator. Child Health Corporation of America. Mar 2010 - Feb 2013.

    Predicting adverse outcomes in children with community-acquired pneumonia. Principal Investigator. National Institute of Allergy and Infectious Diseases. Feb 2008 - January 2013. #K01 AI73729.

    A photo of Mary Staat.

    Mary Allen Staat, MD, MPH
    Director, International Adoption Center

    513-636-2877

    mary.staat@cchmc.org

    Mary Staat, MD, MPH

    Director, International Adoption Center

    Professor, UC Department of Pediatrics

    Phone: 513-636-2877

    Fax: 513-636-6936

    Email: mary.staat@cchmc.org

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    Specialties

    Clinical Interests

    Helicobacter pylori, rotavirus epidemiology, travel medicine and infectious diseases of international adoptees

    Research Interests

    Epidemiology of enteric infections and surveillance of infectious diseases

    Biography

    Mary Allen Staat, MD, MPH, is director of the International Adoption Center and a member of the Infectious Disease Division at Cincinnati Children's Hospital Medical Center.

    Dr. Staat is a board-certified pediatrician and is also board-certified in Infectious Disease and Preventive Medicine. She is an associate professor of Pediatrics at the University of Cincinnati and a faculty member of the Cincinnati Children's Hospital Research Foundation.

    Education and Training

    MD: University of Kentucky, Lexington, Ky., 1986.

    MPH: Johns Hopkins University, Baltimore, Md., 1991.

    Residency: Pediatrics, Baylor College of Medicine, Houston, Texas, 1986-1989; Preventive Medicine, Johns Hopkins University, Baltimore, Md., 1990-1994.

    Fellowship: Infectious Diseases, Baylor College of Medicine, Houston, Texas, 1989-1990; Epidemiology, National Institutes of Health, National Institute of Allergy and Infectious Diseases, Rockville, Md., 1990-1993.

    Certification: Pediatrics, 1989; Preventive Medicine, 1996; Pediatric Infectious Diseases, 1999.

    Publications

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    A photo of Sing Sing Way.

    Sing Sing Way, MD, PhD
    Pauline and Lawson Reed Chair, Division of Infectious Diseases

    513-636-7603

    singsing.way@cchmc.org

    Sing Sing Way, MD, PhD

    Pauline and Lawson Reed Chair, Division of Infectious Diseases

    Associate Professor, UC Department of Pediatrics

    Phone: 513-636-7603

    Email: singsing.way@cchmc.org

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    Specialties

    Infectious diseases; prenatal infection; immunology

    Biography

    Dr. Way is an infectious disease physician-scientist. He cares for infants and children with infection related illness, and provides consultation in the diagnosis and prevention diseases caused by communicable agents. Dr. Way supervises an active basic research laboratory that uses basic immunological approaches to investigate ways to boost host defense and protection against infection. Ongoing projects investigate the immune basis responsible for enhanced susceptibility to infection during pregnancy, the immune pathogenesis of pregnancy complications that occur with maternal infection, and the basic signals required for stimulating immune cell activation.

    Dr. Way trained in the combined MD/PhD program at the Albert Einstein College of Medicine, pediatric residency at the University of California San Francisco, and infectious disease fellowship at the University of Washington. During fellowship training, Dr. Way began investigating the basic immunology and immune pathogenesis of infectious diseases relevant to human, and in particular, infant and child health.

    Dr. Way’s research has been supported by the National Institutes of Health since 2006. Dr. Way’s research has been described in many publications in numerous prestigious scientific journals including Nature, Cell Host & Microbe, PLoS Pathogens, and The Journal of Immunology. The past and ongoing work has also been recognized by numerous prestigious awards including the Infectious Diseases Society of America Wyeth Young Investigator Award, a Basil O’ Conner Award from the March of Dimes Foundation, and the Investigator in Pathogenesis of Infectious Diseases award from the Burroughs Wellcome Fund. 

    Education and Training

    MD PhD: Albert Einstein College of Medicine, Bronx, NY, 1999.

    Residency: University of California San Francisco, San Francisco, CA, 2001.

    Fellowship: University of Washington, Seattle, WA, 2004.

    Publications

    View PubMed Publications

    Grants

    Maternal regulatory T cells control the immune pathogenesis of prenatal infection. Principal Investigator in the Pathogenesis of Infectious Disease. Burroughs Wellcome Fund. 2012-2017.

    The immune pathogenesis of prenatal Listeria monocytogenes infection. Principle Investigator. National Institute of Allergy and Infectious Diseases (NIAID). 2012-2017. R01-AI100934.

    Regulatory T cells dictate the immunity during persistent Salmonella infection. Principle Investigator. National Institute of Allergy and Infectious Diseases (NIAID). 2010-2015. R01-AI087830.

    Physicians

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    Kevin J. Downes, MD
    Staff Physician, Division of Infectious Diseases

    513-636-3511

    kevin.downes@cchmc.org

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    Kevin J. Downes, MD

    Staff Physician, Division of Infectious Diseases

    Clinical Fellow, Division of Clinical Pharmacology

    Phone: 513-636-3511

    Email: kevin.downes@cchmc.org

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    Specialties

    Clinical

    Pediatric infectious diseases

    Research

    Antimicrobial clinical pharmacology; acute kidney injury; cystic fibrosis

    Education and Training

    MD: University of Pennsylvania School of Medicine, Philadelphia, PA, 2008.

    Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2011.

    Fellowship: Pediatric Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2014; Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2014.

    Certification: Pediatrics, 2011.

    Publications

    View PubMed Publications

    Grants

    Urinary biomarkers for aminoglycoside-associated acute kidney injury in Cystic Fibrosis. Principal Investiagtor. Thrasher Research Fund Early Career Award Program Grant. Oct 2012-Sept 2014.

    Advanced Practice Registered Nurses

    A photo of Kelly R. Hicks.

    Kelly R. Hicks, MSN, APRN, CNS
    Clinical Nurse Specialist, Division of Infectious Diseases

    513-636-2877

    kelly.hicks@cchmc.org