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The James M. Anderson Center for Health Systems Excellence at Cincinnati Children's promotes, facilitates and supports a wide range of initiatives to improve the delivery of pediatric healthcare.
Uma R. Kotagal, MBBS, MSc Senior Vice President, Quality, Safety and Transformation; Executive Director, James M. Anderson Center for Health Systems Excellence
Senior Vice President, Quality, Safety and Transformation; Executive Director, James M. Anderson Center for Health Systems Excellence
Professor, UC Department of Pediatrics
Outcomes research; outcomes and cost of early discharge of newborn care; cost effectiveness of neonatal intensive care; cost effectiveness of prenatal care
Uma Kotagal is senior vice president for quality, safety and transformation and executive director of the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital Medical Center.
As director of the Anderson Center, Dr. Kotagal oversees the development of disease management teams and development and institution of evidence-based clinical practice guidelines.
The primary purpose of the Anderson Center is to foster health services research and system transformation with the goal of improving the quality of healthcare delivery, translating knowledge into practice, and building the next generation of improvement leaders.
Dr. Kotagal was director of the neonatal intensive care units at the University Hospital and at Cincinnati Children’s for several years. While practicing, Dr. Kotagal recognized that care and outcomes improvement were a system property. She completed additional training, receiving her master’s of science in clinical epidemiology and clinical effectiveness from the Harvard School of Public Health, and refocused her clinical efforts on quality transformation at a systems level. She was also a visiting scholar at the Center for Risk Analysis at the Harvard School of Public Health and a visiting professor at the Tufts New England Medical Center, in the Division of Clinical Decision Making, completing further training in the field of decision and cost effectiveness analyses.
Dr. Kotagal has published extensively in the field of neonatal outcomes research, including studies on neonatal cost models, and early discharge of newborns. She published the first landmark paper on early discharge programs in the NICU setting.
Dr. Kotagal was born in Bombay, India, where she received her undergraduate and her MBBS from the University of Bombay. She did a rotating internship at the University of Bombay from 1970-1971 and another rotating internship at Detroit General Hospital from 1971-1972.
At Children’s Hospital of Michigan, Dr. Kotagal completed her pediatric residency from 1972-1974 and went on to do a fellowship in neonatology from 1974-1975. She completed a fellowship in neonatal physiology at the University of Cincinnati from 1975-1977.
Dr. Kotagal is a senior faculty member of the Institute for Healthcare. She also serves as chair of the quality steering team of the Ohio Children’s Hospital Association, as a member of the advisory committee of the Toronto Patient Safety Center, as an associate editor of BMJ Quality and Safety and as a member of the Institute of Medicine.
Dr. Kotagal is also a member of various local, regional and national committees in the area of child health.
Ryckman FC, Yelton PA, Anneken AM, Kiessling PE, Schoettker PJ, Kotagal UR. Redesigning intensive care unit flow using variability management to improve access and safety. Jt Comm J Qual Patient Saf. 2009 Nov;35(11):535-43.
Mandel KE, Muething SE, Schoettker PJ, Kotagal UR. Transforming safety and effectiveness in pediatric hospital care locally and nationally. Pediatr Clin North Am. 2009 Aug;56(4):905-18.
Ryckman FC, Schoettker PJ, Hays KR, Connelly BL, Blacklidge RL, Bedinghaus CA, Sorter ML, Friend LC, Kotagal UR. Reducing surgical site infections at a pediatric academic medical center. Jt Comm J Qual Patient Saf. 2009 Apr;35(4):192-8.
Yi MS, Britto MT, Sherman SN, Moyer MS, Cotton S, Kotagal UR, Canfield D, Putnam FW, Carlton-Ford S, Tsevat J. Health values in adolescents with or without inflammatory bowel disease. J Pediatr. 2009 Apr;154(4):527-34.
Britto MT, Byczkowski TL, Anneken AM, Hausfeld J, Schoettker PJ, Farrell MK, Kotagal UR. Improving access to pediatric subspecialty care: initial failures and lessons learned. Qual Manag Health Care. 2008 Oct-Dec;17(4):320-9.
Sparling KW, Ryckman FC, Schoettker PJ, Byczkowski TL, Helpling A, Mandel K, Panchanathan A, Kotagal UR. Financial impact of failing to prevent surgical site infections. Qual Manag Health Care. 2007 Jul-Sep;16(3):219-25.
Mandel KE, Kotagal UR. Pay for performance alone cannot drive quality. Arch Pediatr Adolesc Med. 2007 Jul;161(7):650-5.
Blacklidge M, Kotagal UR, Lazaron L, Schoettker PJ, Kennedy MR, Stultz M, Muething S. Challenges to performance-based assessment for community physicians. J Healthc Qual. 2005 Sep-Oct;27(5):20-7.
Gerhardt WE, Schoettker PJ, Donovan EF, Kotagal UR, Muething SE. Putting evidence-based clinical practice guidelines into practice: an academic pediatric center's experience. Jt Comm J Qual Patient Saf. 2007 Apr;33(4):226-35.
Muething SE, Kotagal UR, Schoettker PJ, Gonzalez del Rey J, DeWitt TG. Family-centered bedside rounds: a new approach to patient care and teaching. Pediatrics. 2007 Apr;119(4):829-32.
Evaline A. Alessandrini, MD, MSCE Director, Quality Scholars Program
Director, Quality Scholars Program
Evaline Alessandrini, MD, MSCE, is an attending physician in the Division of Emergency Medicine at Cincinnati Children’s Hospital Medical Center and a professor of pediatrics at the University of Cincinnati College of Medicine. She is director of the Quality Scholars Program in Health Care Transformation in the James M. Anderson Center for Health Systems Excellence where she leads training for health care faculty to innovate to improve care and rigorously apply quality improvement methods.
Dr. Alessandrini’s research defines outcomes of quality emergency care and develops interventions to improve delivery of emergency care to children. She served as the American Academy of Pediatrics representative to the National Quality Forum’s Steering Committee on Hospital-based Emergency Care and currently serves as the NACHRI representative to the National Quality Forum’s Steering Committee on Ambulatory Care.
MD: Jefferson Medical College, 1988.
BS: Marquette University (Biology, Summa Cum Laude), 1984.
MSCE: Master of Science in Clinical Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, 1999.
Residency: Children’s National Medical Center, Washington, D.C., 1988 -1991.
Chief Residency: Children’s National Medical Center, Washington, D.C., 1991- 1992.
Fellow: Pediatric Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, 1992-1995.
Alessandrini EA, Varadarajan K, Alpern ER, Gorelick MH, Shaw KN, Ruddy RM, Chamberlain JM; Pediatric Emergency Care Applied Research Network. Emergency department quality: an analysis of existing pediatric measures. Academ Emerg Medi. 2011 May;18(5):519-26.
Fiks AG, Alessandrini EA, Forrest CB, Khan S, Localio AR, Gerber A. Electronic medical record use in pediatric primary care. J Am Med Inform Assoc. 2011 Jan 1;18(1):38-44.
Topjian AA, Localio AR, Berg RA, Alessandrini EA, Meaney PA, Pepe PE, Larkin GL, Peberdy MA, Becker LB, Nadkarni VM; American Heart Association National Registry of Cardiopulmonary Resuscitation Investigators. Women of child-bearing age have better inhospital cardiac arrest survival outcomes than do equal-aged men. Crit Care Med. 2010 May;38(5):1254-60.
Alessandrini EA, Alpern ER, Chamberlain JM, Shea JA, Gorelick MH. A New ICD-based Diagnosis Grouping System for Child ED Visits. Acedem Emerg Med. 2010 Feb;17(2):204-13.
Fiks AG, Hunter KF, Localio AR, Grundmeier RW, Bryant-Stephens T, Luberti AA, Bell LM, Alessandrini EA. Impact of Electronic Health Record-based Primary Care Clinical Alerts on Influenza Vaccination for Children and Adolescents with Asthma: A Cluster Randomized Trial. Pediatrics. 2009 Jul;124(1):159-169.
Hibbs AM, Walsh CM, Martin RJ, Truog WE, Lorch SA, Alessandrini EA, Cnaan A, Palermo L, Wadlinger SR, Coburn CE, Ballard PL, Ballard RA. One-Year Respiratory Outcomes of Preterm Infants Enrolled in the Nitric Oxide (to Prevent) Chronic Lung Disease Trial. J Pediatr. 2008 Jun;153 (4):525-529.
Fiks AG, Grundmeier RW, Biggs LM, Localio AR, Alessandrini EA. Impact of clinical alerts within an electronic health record on routine subsequent well child care. Pediatrics. 2008 May; 121:898-905..
Flores AI, Bilker WB, Alessandrini EA. The Effect of Continuity of Care in Infancy on Receipt of Lead, Anemia and Tuberculosis Screening. Pediatrics. 2008 Mar;121(3):e399-406.
Gorelick MH, Alessandrini EA, Cronan K, Shults J. Revised Pediatric Emergency Assessment Tool (RePEAT): A Severity Index for Pediatric Emergency Care. Academic Emergency Medicine. 2007 Apri 14(4):316-23.
Gorelick MH, Knight S, Alessandrini EA, Stanley RM, Chamberlain JM, Kuppermann N, Alpern ER. Pediatric Emergency Care Applied Research Network. Lack of agreement in pediatric emergency department discharge diagnoses from clinical and administrative data sources. Academic Emergency Medicine. 2007;14(7):646-52.
EMSC Network Development Demonstration Project. Co-investigator. Sep 2008 - Sep 2011.
Jeffrey B. Anderson, MD, MPH
Assistant Professor, UC Department of Pediatrics
Pediatric electrophysiology; Syncope; Quality improvement and outcomes
Syncope, nutrition and growth in congenital heart disease, large database analysis, quality improvement
Jeffrey B. Anderson MD, MPH, is an assistant professor of pediatrics with the University of Cincinnati College of Medicine and holds a joint appointment with the Heart Institute and the James M. Anderson Center for Clinical Excellence at Cincinnati Children’s Hospital Medical Center.
Dr. Anderson obtained both his medical degree and his Masters in Public Health from the University of Utah School of Medicine. He completed an internship in internal medicine and pediatrics at the North Carolina Memorial Hospital followed by a pediatrics residency at the North Carolina Children’s Hospital in Chapel Hill, NC. Following a year serving as pediatric chief resident in Chapel Hill, he completed his pediatric cardiology fellowship and advanced training in electrophysiology at Cincinnati Children’s Hospital Medical Center.
Dr. Anderson’s research interests include nutrition in congenital heart disease, syncope in the pediatric population and application of quality improvement methodology to improve outcomes in congenital heart disease. Dr. Anderson has spent the last several years working with infants with congenital heart disease with nutritional failure to better understand the etiology of their growth problems and to design interventions to improve their growth.
Following cardiology fellowship, Dr. Anderson helped establish the Syncope Clinic in the Heart Institute at Cincinnati Children’s Hospital Medical Center, and he continues to direct the work in this clinic.
Anderson JB, Kalkwarf HJ, Kehl JE, Eghtesady P, Marino BS. Low Weight-for-Age Z-Score and Infection Risk After the Fontan Procedure. Ann Thorac Surg. 2011 May;91(5):1460-6.
Anderson JB, Marino BS, Irving SY, García-España JF, Ravishankar C, Stallings VA, Medoff-Cooper B. Poor post-operative growth in infants with two-ventricle physiology. Cardiol Young. 2011 Mar 9:1-9.
Anderson JB, Benson DW. Genetics of sick sinus syndrome. Card Electrophysiol Clin. 2010 Dec 1;2(4):499-507.
Czosek RJ, Anderson JB, Cao J, Knilans TK. Assessment of T-wave oversensing in an infant with an implanted defibrillator. Heart Rhythm. 2010 Oct;7(10):1516-7.
Anderson JB, Beekman RH 3rd, Eghtesady P, Kalkwarf HJ, Uzark K, Kehl JE, Marino BS. Predictors of poor weight gain in infants with a single ventricle. J Pediatr. 2010 Sep;157(3):407-13, 413.e1. Dixon CA, Anderson JB, Ruddy RM, Cripe LH. Infantile-onset Pompe disease: a diagnosis not to miss. Pediatr Emerg Care. 2010 Apr;26(4):293-5. Anderson JB, Beekman RH 3rd, Border WL, Kalkwarf HJ, Khoury PR, Uzark K, Eghtesady P, Marino BS. Lower weight-for-age z score adversely affects hospital length of stay after the bidirectional Glenn procedure in 100 infants with a single ventricle. J Thorac Cardiovasc Surg. 2009 Aug;138(2):397-404.e1.
Anderson J, Kocis K. Echocardiographic evaluation of pericardial effusions and cardiac tamponade in children. Pediatric Ultrasound Today. 2006; 11(8): 137-52. Anderson JB, Fuller TC, Hawkins JA, Brinkman MK, Profaizer T, Shaddy MD. Long-term reduction of panel reactive antibodies in children receiving mycophenolate mofetil after valved allograft placement. Transplantation. 2005 Aug 15;80(3):414-6. Shaddy RE, Fuller TC, Anderson JB, Lambert LM, Brinkman MK, Profaizer T, Hawkins JA. Mycophenolic mofetil reduces the HLA antibody response of children to valved allograft implantation. Ann Thorac Surg. 2004 May;77(5):1734-9.
Julia S. Anixt, MD Pediatrician, Division of Developmental and Behavioral Pediatrics
Pediatrician, Division of Developmental and Behavioral Pediatrics
Attention deficit / hyperactivity disorder (ADHD); autism spectrum disorders (ASD); learning difficulties; developmental and behavioral issues in underserved populations; developmental outcomes in children with congenital heart disease
ADHD; use of shared decision making for the treatment of challenging behavior in children with ASD; the diagnosis and management of behavioral and mental health issues in primary care settings; access to care for underserved populations
Julia Anixt, MD, is a developmental-behavioral pediatrician conducting clinical research on attention deficit/ hyperactivity disorder (ADHD). In particular her work focuses on improving the quality of care for ADHD diagnosis and treatment for children in underserved communities and assessing the impact of parent and youth perceptions about ADHD on treatment decisions. Her research also focuses on implementing shared decision making (SDM) in the clinical setting for families of children with autism spectrum disorders (ASD) contemplating the use of medication to target challenging behaviors.
BS: Haverford College, Haverford, PA, 1996.
MD: University of Maryland School of Medicine, Baltimore, MD, 2001. Residency: Pediatrics, Yale New-Haven Hospital, New Haven, CT, 2004. Fellowship: Robert Wood Johnson Clinical Scholars Program, Johns Hopkins University, Baltimore, MD, 2006; Developmental-Behavioral Pediatrics, University of Maryland, Baltimore, MD, 2008. Certification: General Pediatrics, American Board of Pediatrics, 2004; Developmental and Behavioral Pediatrics, American Board of Pediatrics, 2011.
Froehlich TE, Delgado SV, Anixt JS. Expanding Medication Options for Pediatric ADHD. Current Psychiatry. 2013 Dec;12(12): 20-9.
Anixt JS, Copeland-Linder N, Haynie D, Cheng TL. Burden of Unmet Mental Health Needs in Assault-Injured Youths Presenting to the Emergency Department. Acad Pediatr. 2012 Mar-Apr;12(2):125-30.
Froehlich TE, Anixt JS, Loe IM, Chirdkiatgumchai V, Kuan L, Gilman RC. Update on Environmental Risk Factors for Attention-Deficit/Hyperactivity Disorder. Curr Psychiatry Rep. 2011 Oct;13(5):333-44.
Lipkin PH, Anixt JS. Attention Deficit/ Hyperactivity Disorder (ADHD). In: ACP Smart Medicine [online database]. Philadelphia, American College of Physicians, 2014. Evidence-based, peer-reviewed ADHD diagnostic and treatment guidelines for American College of Physicians Smart Medicine; co-author and co-editor of ADHD module. Original publication date 2009; most recent edition 1/30/2014.
Olaniyan O, dosReis S, Garriett V, Mychailyszyn MP, Anixt J, Rowe PC, Cheng TL. Community Perspectives of Childhood Behavioral Problems and ADHD among African-American Parents. Ambul Pediatr. 2007 May-Jun;7(3):226-31.
dosReis S, Butz A, Lipkin PH, Anixt JS, Weiner CL, Chernoff R. Attitudes About Stimulant Medication for Attention-Deficit/Hyperactivity Disorder Among African American Families in an Inner City Community. J Behav Health Serv Res. 2006 Oct;33(4):423-30.
Keyser E, Peralta L, Cade T, Miller S, Anixt J. Functional Aerobic Impairment in Adolescents Seropositive for HIV: A Quasiexperimental Analysis. Arch Phys Med Rehabil. 2000 Nov;81(11):1479-84.
Interventions for children with Attention and Reading Disorders. Co-Investigator. National Institutes of Health. Dec 2009-Nov 2014. R01 HD060617.
Shared Decision Making to Improve Care and Outcomes for Children with Autism. Principal Investigator. Cincinnati Children’s Hospital Medical Center Place Outcomes Research Award. Jul 2013 - Jun 2015.
Patrick W. Brady, MD, MSc Attending Physician, Hospital Medicine
Attending Physician, Hospital Medicine
Patient safety; quality improvement; hospital medicine
Patrick Brady, MD, MSc, has clinical training in pediatrics and hospital medicine as well as advanced training in epidemiology and biostatistics and in the science of improvement through two 6-month courses at Cincinnati Children’s. He has completed coursework at the graduate level in human factors and through the Systems Engineering in Patient Safety (SEIPS) workshop led by NIH-funded researchers at the University of Wisconsin.
Their pilot work on a system to proactively identify, mitigate and escalate risk has resulted in measured decreases in patient harm and deterioration. The Academy for Healthcare Improvement recently recognized this work with top prize at its international meeting. Dr. Brady's current focus builds logically on this work, and his research team includes clinical and methodological experts with impressive research portfolios both inside and outside of healthcare.
In summary, Dr. Brady has the training, experience and collaborators needed to study and improve the care of patients at risk for deterioration, to define highly reliable interventions that deliver the right therapeutics early, and to improve the safety of patients in our increasingly complex healthcare system.
MD: Washington University in St. Louis, St. Louis, MO, 2003.
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
MSc: University of Cincinnati Department of Epidemiology and Biostatistics.
Mussman G, Parker M, Statile A, Sucharew H, Brady PW. Suctioning and length of stay in infants hospitalized with bronchiolitis. Archives of Pediatrics and Adolescent Medicine. 2013. Epub ahead of print.
Bonafide CP, Brady PW, Keren R, Conway PH, Marsolo K, Daymont C. Development and validation of heart and respiratory rate centile curves for hospitalized children. Pediatrics. 2013. Epub ahead of print.
Brady PW, Muething S, Kotagal U et al. Improving situation awareness to reduce serious safety events and UNSAFE transfers of pediatric inpatients. Pediatrics.2012.
Meuthing SE, Goudie A, Schoetkker PJ, Donnelly LF, Goodfriend MA, Bracke TM, Brady PW, Wheeler DS, Anderson JM, Kotagal UR. Reduction in serious safety events across an academic children's hospital. Pediatrics. 2012 Aug;130(2):e423-31.
Kaplan HC, Brady PW, Dritz M, Hooper DK, Linam M, Froehle C, Margolis PA. The Influence of Context on Quality Improvement Success in Healthcare: A Systematic Review of the Literature. Milbank Quarterly. 2010 Dec;88(4):500-59.
Brady PW, Conway PH, Goudie A. Length of intravenous antibiotic therapy and treatment failure in infants with urinary tract infections. Pediatrics. 2010 Aug;126(2):196-203.
Bigham MT, Brady PW, Manning PB, Jacobs BR, Kimball TR, Wong HR. Therapeutic application of intrapericardial tissue plasminogen activator (t-PA) in a 4 month-old child with complex fibropurulent pericarditis. Pediatr Crit Care Med. 2008 Jan;9(1):e1-e4.
William B. Brinkman, MD, MEd, MSc Director of Research Section, Division of General and Community Pediatrics
Director of Research Section, Division of General and Community Pediatrics
Methods Expert, Evidence and Measures Team, James M. Anderson Center for Health Systems Excellence
Research Director, Cincinnati Pediatric Research Group
Associate Professor, UC Department of Pediatrics
Dr. Brinkman researches shared decision-making between patients, parents, and clinicians to promote high value care that is evidence-based and family-centered. He collaborates to develop interventions to facilitate shared decision-making across a wide-range of clinical contexts.
Dr. Brinkman serves as director of the Research Section in the Division of General & Community Pediatrics and the research director for the Cincinnati Pediatric Research Group, a practice-based research network. He also serves as a methods expert for the James M. Anderson Center Evidence & Measures team. In this role, he is building an infrastructure to support shared decision-making throughout Cincinnati Children's.
MD: St. Louis University, St. Louis, MO, 1999.
Residency: Pediatrics, The Children's Memorial Hospital, Northwestern University, Feinberg School of Medicine, Chicago, IL, 2002.
Chief Residency: Pediatrics, The Children's Memorial Hospital, Chicago, IL, 2003.
Fellowship: NRSA Primary Care Research Fellowship, General & Community Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2006.
MEd: University of Cincinnati, Cincinnati, OH, 2006.
MSc: University of Cincinnati, Cincinnati, OH, 2013.
Certification: Pediatrics, 2002.
Brady PW, Brinkman WB, Simmons JM, Yau C, White CM, Kirkendall ES, Schaffzin JK, Conway PH, Vossmeyer MT. Oral antibiotics at discharge for children with acute osteomyelitis: a rapid cycle improvement project. BMJ Qual Saf Online First. Dec 17, 2013.
Lipstein EA, Brinkman WB, Sage J, Lannon CM, Morgan DeWitt E. Understanding treatment decision making in juvenile idiopathic arthritis: a qualitative assessment. Pediatr Rheumatol Online J. 2013 Sep 30; 11(1):34.
Brinkman WB, Hartl Majcher J, Poling L, Shi G, Zender M, Sucharew H, Britto MT, Epstein JN. Shared Decision-Making to Improve Attention-Deficit/Hyperactivity Disorder Care. Patient Educ Couns. 93 (2013) 95–101.
Jerardi KE, Elkeeb D, Weiser J, Brinkman WB. Rapid Implementation of Evidence Based Guidelines for Imaging after First Urinary Tract Infection. Pediatrics. 2013;132:e749–e755.
Brinkman WB, Sherman SN, Zmitrovich AR, Visscher MO, Crosby LE, Phelan KJ, Donovan EF. In their own words: Adolescent views on ADHD and their evolving role managing medication. Acad Pediatr. 2012 Jan; 12(1):53-61.
Brinkman WB, Hartl J, Rawe L, Sucharew H, Britto MT, Epstein JN. Physicians’ Shared Decision Making Behaviors in Attention-Deficit/Hyperactivity Disorder Care. Arch Pediatr Adolesc Med. 2011 Nov; 165(11):1013-9.
Lipstein EA, Brinkman WB, Britto MT. What Is Known about Parent’s Treatment Decisions? A Narrative Review of Pediatric Decision Making. Med Decis Making. 2012 Mar-Apr;32(2):246-58.
Brinkman WB, Sherman SN, Zmitrovich AR, Visscher MO, Crosby LE, Phelan KJ, Donovan EF. Parental Angst Making and Revisiting ADHD Treatment Decisions. Pediatrics. 2009 Aug; 124: 580-9.
Brinkman WB, Geraghty SR, Lanphear BP, Khoury JC, Gonzalez del Rey JA, DeWitt TG, Britto MT. Effect of Multi-Source Feedback on Resident Communication Skills and Professionalism. A Randomized Controlled Trial. Arch Pediatr Adolesc Med. 2007 Jan; 161: 44-9.
Brinkman WB, Geraghty SR, Lanphear BP, Khoury JC, Gonzalez del Rey JA, DeWitt TG, Britto MT. Evaluation of Resident Communication Skills and Professionalism: A Matter of Perspective?Pediatrics. 2006 Oct; 18: 1371-9.
Medication Continuity in Children Treated for ADHD. Principal Investigator. Mentored Patient-Oriented Research Career Development Award, National Institute of Mental Health. Jan 2010–Nov 2014.
Developing New Technologies to Improve ADHD Medication Continuity. R34, National Institute of Mental Health. Apr 2014–Mar 2017.
Shared Decision Making to Improve Care and Outcomes for Children with Autism. Co-Principal Investigator. Cincinnati Children’s Place Research Outcomes Award. Jul 2013 – Jun 2015.
Testing and Spread of Shared Decision Making Tools across Learning Networks. Co-Principal Investigator. Subproject on Agency for Healthcare Research and Quality Cincinnati Children’s Center for Education and Research on Therapeutics (CERTs). Sep 2013-Aug 2015.
Partnering with Parents to Support Decision-Making About Hydroxyurea in Pediatric Sickle Cell Disease. Co-Principal Investigator. Subproject on Agency for Healthcare Research and Quality Cincinnati Children’s Center for Education and Research on Therapeutics (CERTs). Sep 2013-Aug 2015.
Evaluation of an Intervention for Improving Community-Based Pediatric ADHD Care. (PI: Epstein) Co-Investigator. National Institute of Mental Health. Aug 2010-May 2015.
Collaborative Ohio Inquiry Networks (COIN) Research Center. (PI: Werner) Co-investigator. Agency for Healthcare Research and Quality. Sep 2012-Aug 2017.
Maria T. Britto, MD, MPH Interim Division Director, Adolescent and Transition Medicine
Interim Division Director, Adolescent and Transition Medicine
Director, Center for Innovation in Chronic Disease Care
Assistant Vice President, Chronic Care Systems
Chronic illness in adolescents; chronic disease care of adolescents; health care quality
Chronic illness in adolescents; health care quality; quality of life; health care preferences of adolescents with chronic illness
Visit the Britto Lab.
Maria Britto, MD, MPH, is a pediatrician, professor of pediatrics, founding director of the Center for Innovation in Chronic Disease Care, and research faculty mentoring lead for the Anderson Center. She holds an MPH in epidemiology and a graduate certificate in medical informatics. She served as the assistant vice president of Chronic Care Systems from 2007 to 2012.
Her research focuses on health care needs and preferences of adolescents with chronic conditions and on interventions to improve health outcomes. She is the director of the Center for Innovation in Chronic Disease Care, which seeks to accelerate improvement in outcomes for children and adolescents with chronic conditions by developing and evaluating new methods of care delivery and by applying innovative approaches to quality improvement in chronic diseases. She has served as a mentor for numerous NIH career development awards, as well as numerous other students, residents and junior faculty.
MD: University of Virginia, Charlottesville, VA, 1987.
MPH: Epidemiology, University of North Carolina, Chapel Hill, NC, 1995.
Residency: Medicine/Pediatrics, University of North Carolina Hospitals, Chapel Hill, NC, 1987-1991.
Chief Resident: Pediatrics, Department of Pediatrics, University of North Carolina Hospitals, Chapel Hill, NC, 1991-1992.
Robert Wood Johnson Clinical Scholars Program: University of North Carolina, Chapel Hill, NC, 1993-1995.
Graduate Certificate: Biomedical Informatics, Oregon Health and Science University, Portland, OR, 2008.
Board Certifications: American Board of Internal Medicine, 1991; Recertified 2001; American Board of Pediatrics, 1992; Recertified 1999, 2007; American Board of Pediatrics, Certification in Adolescent Medicine, 1997; Recertified 2007 and 2011.
Licensure: Ohio, July 1995.
Britto MT, Byczkowski TL, Hesse EA, Munafo JK, Vockell AL, Yi MS. Overestimation of impairment-related asthma control by adolescents. J Pediatr. 2011 Jun;158(6):1028-1030.e1
Byczkowski TL, Munafo JK, Britto MT. Variation in use of Internet-based patient portals by parents of children with chronic disease. Arch Pediatr Adolesc Med. 2011 May;165(5):405-11.
Britto MT, Tivorsak TL, Slap GB. Adolescents' needs for health care privacy. Pediatrics. 2010 Dec;126(6):e1469-76.
Britto MT, Jimison HB, Munafo JK, Wissman J, Rogers ML, Hersh W. Usability testing finds problems for novice users of pediatric portals. J Am Med Inform Assoc. 2009 Sep-Oct;16(5):660-9.
Sawyer SM, Drew S, Yeo MS, Britto MT. Adolescents with chronic conditions: challenges living, challenges treating. Lancet 2007; 369(9571):1481-89.
Britto MT, Anderson JM, Kent WM, Mandel KE, Muething SM, Kaminski GM, Schoettker PJ, Pandzik G, Carter LA, Kotagal UR. Cincinnati Children’s Hospital Medical Center: Transforming care for children and families. Jt Comm J Qual Patient Saf 2006 Oct;32(10):541-548.
Britto MT, DeVellis RF, Hornung RW, DeFriese GH, Atherton HD, Slap GB. Health care preferences and priorities of adolescents with chronic conditions. Pediatrics, 2004 114(5):1272-80.
Yi MS, Tsevat J, Wilmott RW, Kotagal UR, Britto MT. The impact of treatment of pulmonary exacerbations on the health-related quality of life of patients with cystic fibrosis: foes hospitalization make a difference. J Pediatr, 2004; 144(6):711-718.
Britto MT, Kotagal UR, Hornung RW, Atherton HD, Tsevat J, Wilmott RW. Impact of recent pulmonary exacerbations on quality of life in cystic fibrosis. Chest. 2002;121:64-72.
Britto MT, Garrett JM, Dugliss MAJ, Daeschner HR, Johnson CA, Leigh MW, Majure JM, Schultz WH, Konrad TR. Risky behavior in teens with cystic fibrosis or sickle cell disease: A multi-center study. Pediatrics. 1998;101:250-256.
Open Source Science: Transforming Chronic Care. Co-Investigator. Oct 2009 – Sep 2014.
Center of Excellence on Quality of Care Measures for Children with Complex Needs. Site Primary Investigator. Mar 2011 – Feb 2015.
Improving Sickle Cell Transitions of Care through Health Information Technology, Phase 1. Site Primary Investigator. Aug 2012 – May 2014.
Adam C. Carle, MA, PhD
Adam Care, MA, PhD, is a clinically and quantitatively trained investigator who uses advanced statistical methods to study health disparities among adults and children, especially children with special health care needs.
Dr. Carle uses latent variable models like item response theory, confirmatory factor analysis, structural equation modeling, and multilevel models to examine health disparities across traditionally underserved and underrepresented groups (e.g., US minorities). He seeks to better understand individual and contextual variables in comparative effectiveness research, health disparities, and public policy for children at individual, local, state, and national levels.
Dr. Carle received his PhD in 2003 from Arizona State University. Following his doctoral degree, Dr. Carle completed a a two-year post-doctoral appointment at the US Census Bureau. He spent three years as an assistant professor of psychology at the University of North Florida before joining Cincinnati Children’s Hospital Medical Center.
Visit the Carle Lab site.
Fairbrother GL, Carle AC, Cassedy A, Newacheck PW. The impact of parental job loss on children's health insurance coverage. Health Aff (Millwood). 2010 Jul;29(7):1343-9.
Carle AC. Mitigating systematic measurement error in comparative effectiveness research in heterogeneous populations. Med Care. 2010 Jun;48(6 Suppl):S68-74.
Carle AC, Simpson LA. Identifying child health priorities for comparative effectiveness research from the IOM's Report. Acad Pediatr. 2010 May-Jun;10(3):155-8.
Carle AC, Blumberg SJ, Poblenz C. Internal Psychometric Properties of the Children with Special Health Care Needs Screener. Acad Pediatr. 2010 Mar 13.
Bethell C, Simpson L, Stumbo S, Carle AC, Gombojav N. National, state, and local disparities in childhood obesity. Health Aff (Millwood). 2010 Mar-Apr;29(3):347-56.
Carle AC. Interpreting the Results of Studies Using Latent Variable Models to Assess Data Quality: An Empirical Example Using Confirmatory Factor Analysis. Quality & Quantity. 2010; 44(3):483-497.
Blumberg SJ, Carle AC. The Well-Being of the Health Care Environment for Children with Special Health Care Needs and Their Families: A Latent Variable Approach. Pediatrics. 2009 Dec;124 Suppl 4:S361-7.
Carle AC, Blumberg SJ, Poblenz C. Psychometric properties of the Children with Special Health Care Needs Screener in the collective population: Evidence for reliability as fielded in the National Survey of Children with Special Health Care Needs. Academic Pediatrics. 2009 Dec;124 Suppl 4:S375-83.
Kasehagen L, Kane D, Punyko J, Carle AC, Penziner A, Thorson S. What factors are associated with receipt of the services necessary to make transitions to all aspects of adult life relative to states’ ranking? Pediatrics. 2009 Dec;124 Suppl 4:S375-83.
Carle AC. Fitting multilevel models in complex survey data with design weights: Recommendations. BMC Medical Research Methodology 2009 Jul;9:49.
Nancy M. Daraiseh, PhD
Occupational health and safety; human factors; patient safety; health outcomes; stress
Nancy Daraiseh, PhD, specializes in occupational safety and health with over 13 years of experience and 20 publications focusing on studying workload and the work environment and their impact on health outcomes in employees in various industries. Dr. Daraiseh has obtained four pilot grants from the Centers for Disease Control and Prevention/National Institute for Occupational Safety and Health to investigate work-related musculoskeletal symptoms and other health outcomes in nursing personnel. As a post-doctoral fellow at the University of Cincinnati, she was awarded a grant to conduct a comprehensive risk assessment of engineering laboratories’ safety and best practices at a regional university. She is currently collaborating with the Division of Child Psychiatry to examine interventions to improve both staff and patient safety. Dr. Daraiseh is also studying the effectiveness of patient handling equipment in a pediatric-care population by examining the impact on staff injuries and patient outcomes.
Dr. Daraiseh is a member of the Institute of Industrial Engineers, The Human Factors & Ergonomics Society and the Society for Health Systems. She is a reviewer for the International Journal of Industrial Ergonomics, Human Factors & Ergonomic Society, Ergonomics and The Institute of Industrial Engineers.
PhD: University of Cincinnati, College of Engineering, Cincinnati, OH, 2004.
MS: University of Cincinnati, College of Engineering, Cincinnati, OH, 1999.
Schaffer P, Daraiseh N, Daum L, Mendez E, Lin L, Huth M. Pediatric inpatient falls and injuries: A descriptive analysis of risk factors. Journal for Specialists in Pediatric Nursing. 2012;17(1), 10-18.
Chen J, Davis LS, Davis K, Pan W, Daraiseh N. Physiological and Behavioral Response Patterns at Work among Hospital Nurses. Journal of Nursing Management. 2011; 19, 57-68.
Daraiseh N, Cronin S, Davis LS, Shell R, Karwowski W. Low back symptoms among hospital nurses, associations to individual factors and pain in multiple body regions. International Journal of Industrial Ergonomics. 2010; 40, 19-24.
Dabke S, Salem O, Genaidy A, Daraiseh N. Job satisfaction of women in construction trades. Journal of Construction Engineering and Management. 2008;134(3), 205-216.
Moayed F, Daraiseh N, Shell R, Salem S. Workplace Bullying: A systematic review of risk factors and outcomes. Theoretical Issues in Ergonomics Science. 2006;7(3), 311-327.
Edward F. Donovan, MD Director, Child Policy Research Center
Director, Child Policy Research Center
Emeritus, UC Department of Pediatrics
Population health; quality improvement research; perinatal epidemiology
Kaplan HC, Lannon C, Walsh MC, Donovan EF; Ohio Perinatal Quality Collaborative. Ohio statewide quality-improvement collaborative to reduce late-onset sepsis in preterm infants. Pediatrics. 2011 Mar;127(3):427-35.
Kaplan HC, Tabangin ME, McClendon D, Meinzen-Derr J, Margolis PA, Donovan EF. Understanding variation in vitamin A supplementation among NICUs. Pediatrics. 2010 Aug;126(2):e367-73.
Donovan EF, Besl J, Paulson J, Rose B, Iams J; Ohio Perinatal Quality Collaborative. Infant death among Ohio resident infants born at 32 to 41 weeks of gestation. Am J Obstet Gynecol. 2010 Jul;203(1):58.e1-5.
SUPPORT Study Group of the Eunice Kennedy Shriver NICHD Neonatal Research Network, Finer NN, Carlo WA, Walsh MC, Rich W, Gantz MG, Laptook AR, Yoder BA, Faix RG, Das A, Poole WK, Donovan EF, Newman NS, Ambalavanan N, Frantz ID 3rd, Buchter S, Sánchez PJ, Kennedy KA, Laroia N, Poindexter BB, Cotten CM, Van Meurs KP, Duara S, Narendran V, Sood BG, O'Shea TM, Bell EF, Bhandari V, Watterberg KL, Higgins RD. Early CPAP versus surfactant in extremely preterm infants. N Engl J Med. 2010 May 27;362(21):1970-9.
Donovan EF, Lannon C, Bailit J, Rose B, Iams JD, Byczkowski T; Ohio Perinatal Quality Collaborative Writing Committee. A statewide initiative to reduce inappropriate scheduled births at 36.0 - 38.0 weeks' gestation. Am J Obstet Gynecol. 2010 Mar;202(3):243.e1-8.
Morris BH, Oh W, Tyson JE, Stevenson DK, Phelps DL, O'Shea TM, McDavid GE, Perritt RL, Van Meurs KP, Vohr BR, Grisby C, Yao Q, Pedroza C, Das A, Poole WK, Carlo WA, Duara S, Laptook AR, Salhab WA, Shankaran S, Poindexter BB, Fanaroff AA, Walsh MC, Rasmussen MR, Stoll BJ, Cotten CM, Donovan EF, Ehrenkranz RA, Guillet R, Higgins RD; NICHD Neonatal Research Network. Aggressive vs. conservative phototherapy for infants with extremely low birth weight. N Engl J Med. 2008 Oct 30;359(18):1885-96. Donovan EF, Ammerman RT, Besl J, Atherton H, Khoury JC, Altaye M, Putnam FW, Van Ginkel JB. Intensive home visiting is associated with decreased risk of infant death. Pediatrics. 2007 Jun;119(6):1145-51.
Fanaroff AA, Stoll BJ, Wright LL, Carlo WA, Ehrenkranz RA, Stark AR, Bauer CR, Donovan EF, Korones SB, Laptook AR, Lemons JA, Oh W, Papile LA, Shankaran S, Stevenson DK, Tyson JE, Poole WK; NICHD Neonatal Research Network. Trends in neonatal morbidity and mortality for very low birthweight infants. Am J Obstet Gynecol. 2007 Feb;196(2):147.el-8.
Clark E, Donovan E, Schoettker P. From outdated to updated, keeping clinical guidelines valid. Int J Qual Health Care. 2006 Jun;18(3):165-6.
Linda M. Dynan, PhD
Adjunct Research Associate Professor
Dynan LM, Goudie A, Smith RB, Fairbrother G, Simpson LA. Differences in Inpatient Pediatric Quality of Care among Non-Safety-Net, Safety-Net and Children’s Hospitals. Pediatrics. 2013.
Smith RB, Dynan LM, Fairbrother G, Chabi G, Simpson L. Medicaid, Hospital Financial Stress, and the Incidence of Adverse Medical Events for Children. Health Services Research. 2012 Aug;47(4):1621-1641.
Dynan, LM. The contribution of economists to understanding racial health disparities in the US. Atlantic Economic Journal. 2009;37(3):213-233.
Dynan L, Stein R, David G, Kenny LC, Eckman M, Short AD. Determinants of hospitalist efficiency: a qualitative and quantitative study. Med Care Res Rev. 2009 Dec;66(6):682-702. Dynan LM. A micro-simulation based decomposition of the health status gap between US blacks and whites. New York Economic Journal. 2008;39:3-27.
Dynan LM. The impact of medical education reform on the racial health status gap, 1920-1930: a difference-in-differences analysis. Review of Black Political Economy. 2007;34(3-4):245-258.
Bazzoli GJ, Dynan L, Burns LR, Yap C. Two decades of organizational change in health care: what have we learned?Med Care Res Rev. 2004 Sep;61(3):247-331. Burns LR, Bazzoli GJ, Dynan L, Wholey DR. Impact of HMO market structure on physician-hospital strategic alliances. Health Serv Res. 2000 Apr;35(1 Pt 1):101-32. Bazzoli GJ, Dynan L, Burns LR, Lindrooth R. Is provider capitation working? Effects on physician-hospital integration and costs of care. Med Care. 2000 Mar;38(3):311-24. Bazzoli GJ, Dynan L, Burns LR. Capitated contracting of integrated health provider organizations. Inquiry. 2000 Winter;36(4):426-44.
Linda M. Goldenhar, PhD
Espay AJ, Goldenhar LM, Voon V, Schrag A, Burton N, Lang AE. Opinions and Clinical Practices related to Diagnosing and Managing Patients with Psychogenic Movement Disorders: an International Survey of Movement Disorder Society Members. Movement Disorders. 2009;24(9):1366-74.
Goldenhar LM, Margolin, EG, Warshaw, G. Impact of extracurricular geriatric medicine training: A model based on student reflections of health care delivery to the elderly. Journal of the American Geriatrics Society. 2008;56(3):548–552. Coberly LC, Goldenhar LM. Ready or Not, Here They Come: Acting Interns’ Experience and Competency Performing Basic Medical Procedures. Journal of General Internal Medicine. 2007;Vol 22(4):491-494.
Goldenhar LM, Kues, JR. Effectiveness of a Geriatric Medical Student Scholar’s Program: A Qualitative Assessment. Journal of American Geriatrics Society. 2006;54;527-534. Bennett AJ, Goldenhar LM, Stanford K. Utilization of a Formative Evaluation Card in a Psychiatry Clerkship. Academic Psychiatry. 2006;30(4):319-324. Golnik K, Goldenhar LM. The Ophthalmic Clinical Evaluation Exercise (OCEX): Reliability Determination. Ophthalmology. 2005;112(10):1649-1654 Goldenhar LM, LaMontange AD. Katz T, Heaney C, Landsbergis P. The Intervention Research Process in Occupational Safety and Health: An overview from the NORA Intervention Effectiveness Research Team. Journal of Occupational and Environmental Medicine. 2001;43(7):616-622.Goldenhar LM, Swanson NG, Hurrell JJ, Ruder A, Deddens J. Job Stressors and Adverse Outcomes for Female Construction Workers. Journal of Occupational Health Psychology. 1998;3(1):19-32. Goldenhar LM, Schulte PA. Intervention research in occupational health and safety. Journal of Occupational Medicine. 1994;36(7):763-775.
Samuel P. Hanke, MD Quality Scholar in Healthcare Transformation, James M. Anderson Center for Health Systems Excellence
Quality Scholar in Healthcare Transformation, James M. Anderson Center for Health Systems Excellence
Inpatient and general cardiology
Quality improvement, hospital care transitions, readmission
Dr. Hanke is an assistant professor in clinical pediatrics in the Heart Institute and a quality scholar in healthcare transformation with the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s. Dr. Hanke received his medical degree from the University of Louisville and completed his pediatric residency at Cincinnati Children’s. He later served as pediatric chief resident before completing a fellowship in pediatric cardiology at Cincinnati Children's.
His clinical areas of interest are as cardiac hospitalist and general outpatient cardiologist. Currently his research is in hospital care transitions evaluating their potential impact on hospital readmissions in patients with congenital heart disease. Additionally, he is focused on the prevention of sleep related deaths in infancy and highly active in safe sleep education and advocacy.
BS: University of Dayton, Dayton, OH, 2002.MD: University of Louisville, Louisville, KY, 2006.Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2009.Chief Residency: Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2010.
Fellowship: Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2010-2013.Certification: Pediatrics, 2009.
David M. Hartley, PhD, MPH
Infectious disease epidemiology; public health surveillance; mathematical and computer modeling
PhD: University of Maryland Baltimore County, Baltimore, MD, 1996.
MPH: George Washington University, Washington, DC, 2006.
Smith DL, Perkins TA, Reiner Jr RC, Barker CM, Niu T, Chaves LF, Ellis AM, George DB, Le Menach A, Pulliam J, Bisanzio D, Buckee C, Chiyaka C, Cummings DAT, Garcia AJ, Gatton ML, Gething PW, Hartley DM, Johnston G, Klein EY, Michael E, Lindsay SW, Lloyd AL, Pigott DM, Reisen WK, Ruktanonchai N, Singh B, Stoller J, Tatem AJ, Kitron U, Hay SI, Scott TW. Recasting the Theory of Mosquito-Borne Pathogen Transmission Dynamics and Control. Trans R Soc Trop Med Hyg. 2014 Apr;108(4):185-87.
Hartley DM. Using social media and other Internet data for public health surveillance: The importance of talking. Milbank Q. 2014 Mar;92(1):34-9.
Barboza P, Vaillant L, Le Strat Y, Hartley DM, Nelson NP, Mawudeku A, Madoff LC, Linge JP, Collier N, Brownstein JS, Astagneau P. Factors influencing performance of Internet-based biosurveillance systems used in epidemic intelligence for early detection of infectious diseases outbreaks. PLoS One. 2014 Mar 5;9(3):e90536.
Hartley DM, Nelson NP, Arthur RR, Barboza P, Collier N, Lightfoot N, Linge JP, van der Goot E, Mawudeku A, Madoff LC, Vaillant L, Walters R, Yangarber R, Mantero J, Corley CD, Brownstein JS. An overview of Internet biosurveillance. Clin Microbiol Infect. 2013 Nov;19(11):1006-13.
Barker CM, Niu T, Reisen WK, Hartley DM. Data-driven modeling to assess receptivity for Rift Valley fever virus. PLoS Negl Trop Dis. 2013 Nov 14;7(11): e2515.
Nelson NP, Brownstein J, Hartley DM. Event-based biosurveillance of respiratory disease in Mexico, 2007-2009: Connection to influenza A(H1N1)v? Euro Surveill. 2010 Jul 29;15(30).
Nelson NP, Yang L, Reilly AR, Hardin JE, Hartley DM. Event-based Internet Biosurveillance: Relation to Epidemiological Observation. Emerg Themes Epidemiol. 2012 Jun 18;9(1):4.
Hartley DM, Barker CM, Le Menach A, Niu T, Gaff HD, Reisen WK. The effects of temperature on the emergence and seasonality of West Nile virus in California. Am J Trop Med Hyg. 2012 May;86(5):884-94.
Hartley DM, Morris JG Jr, Smith DL. Epidemiological Implications of Hyperinfectivity: A critical element in the ability of V. Cholerae to cause epidemics? PloS Med. 2006 Jan;3(1):e7.
Niu T, Gaff HD, Papelis YE, Hartley DM. An epidemiological model of Rift Valley fever with spatial dynamics. Comput Math Methods Med. 2012;2012:138757.
David K. Hooper, MD, MS Pediatric Nephrologist, Division of Nephrology
Pediatric Nephrologist, Division of Nephrology
Nephrology; kidney transplantation; quality improvement
Jointly appointed in the Division of Nephrology and Hypertension and the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital, Dr. Hooper's aim is to improve clinical outcomes for pediatric kidney transplant recipients through research in personalized care and the design of reliable healthcare systems.
Dr. Hooper's research training includes a master's degree in clinical and translational research from the University of Cincinnati, in addition to advanced training in quality improvement methodology through the Quality Scholars in Healthcare Transformation program at Cincinnati Children’s Hospital Medical Center.
Dr. Hooper's career focus is to combine clinical outcomes research with quality improvement to reliably prevent cardiovascular disease, the leading cause of long-term death and disability in pediatric transplant recipients.
MD: University of Utah, Salt Lake City, Utah, 2003.
Residency: Cincinnati Children's Hospital, Cincinnati, Ohio, 2006.
Chief Residency: Cincinnati Children's Hospital, Cincinnati, Ohio, 2007.
MS: University of Cincinnati, Cincinnati, Ohio, 2010.
Fellowship: Cincinnati Children's Hospital, Cincinnati Ohio, 2010; Quality Scholar in Healthcare Transformation, James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital, Cincinnati, Ohio, 2011.
Certification: Pediatrics, 2006.
Hooper DK, Kirby C, Margolis P, Goebel J. Reliable Individualized Monitoring Improves Cholesterol Control in Kidney Transplant Recipients. Pediatrics. Epub ahead of print. 2013.
Hooper DK, Williams JC, Carle AC, Amaral S, Chand DH, Ferris ME, Patel HP, Licht C, Barletta GM, Bastian V, Mitsnesfes M, Patel UD. The Quality of Cardiovascular Disease Care and Formal Transition for Adolescents with Kidney Disease. Pediatric Nephrology. Epub ahead of print. 2013.
Hooper DK, Fukuda T, Logan B, Gardiner R, Roy-Chaudhury A, Kirby C, Vinks A, Goebel J. Risk of Tacrolimus Toxicity in CYP3A5 Non-Expressors Treated with Intravenous Nicardipine After Kidney Transplantation. Transplantation. 2012 Apr;93(8):806-812.
Saldaña SN, Hooper DK, Froehlich TE, Campbell KM, Prows CA, Sadhasivam s, Nick TG, Seid M, Vinks AA, Glauser TA. Characteristics of Successful Recruitment in Prospective Pediatric Pharmacogenetic Studies. Clinical Therapeutics. 2011 Feb;15:88-95.
Hooper DK, Carle AC, Schuchter J, Goebel J. Interaction between tacrolimus and intravenous nicardipine in the treatment of post-kidney transplant hypertension at pediatric hospitals. Pediatr Transplant. 2011 Feb;15(1):88-95.
Kaplan HC, Brady PW, Dritz MC, Hooper DK, Linam WM, Froehle CM, Margolis P. The influence of context on quality improvement success in health care: a systematic review of the literature. Milbank Q. 2010 Dec;88(4):500-59.
Hooper DK. The Impact of CYP3A5 Genotype on the Interaction Between Tacrolimus and Intravenous Nicardipine in Kidney Transplant Recipients. University of Cincinnati. 2010 Aug 17.
Hooper DK, Hawkins JA, Fuller TC, Profaizer T, Shaddy RE. Panel-reactive antibodies late after allograft implantation in children. Ann Thorac Surg. 2005 Feb;79(2):641-4. Raetz EA, Kim MK, Moos P, Carlson M, Bruggers C, Hooper DK, Foot L, Liu T, Seeger R, Carroll WL. Identification of genes that are regulated transcriptionally by Myc in childhood tumors. Cancer. 2003 Aug 15;98(4):841-53. Lirazan MB, Hooper D, Corpuz GP, Ramilo CA, Bandyopadhyay P, Cruz LJ, Olivera BM. The spasmodic peptide defines a new conotoxin superfamily. Biochemistry. 2000 Feb 22;39(7):1583-8.
Srikant B. Iyer, MD, MPH Attending Physician, Division of Emergency Medicine
Attending Physician, Division of Emergency Medicine
Acute pain management; emergent care of children with congenital heart disease; acute management of sepsis/septic shock
Process and systems improvement; patient flow/capacity management; acute pain management in ED settings; healthcare delivery system redesign
Srikant Iyer, MD, MPH, completed his residency in categorical pediatrics and fellowship in pediatric emergency medicine at Cincinnati Children’s Hospital Medical Center in 2000 and 2005, respectively. He also completed his Masters degree in 2005 from the Harvard School of Public Health.
Dr. Iyer’s initial research efforts were directed toward improving efficiency of care, specifically via the use of point-of-care testing. These efforts were funded by an industry-sponsored grant from Quidel, Inc., as well as a Cincinnati Children's T32 Award from 2004-2006.
His interests broadened to include both improvements in timeliness and efficiency, specifically toward improving acute pain management in acute care settings. These efforts were funded by a Place Outcomes Award and an award from the Mayday Fund from 2008-2010.
Dr. Iyer’s current work has broadened further to involve improvements in timeliness of care for patients seeking care in open access systems. His most recent effort has been directed toward designing an emergency department fast track care stream to improve the timeliness of care delivery in this system. To aid him in these efforts, he has received formal training in QI methods, LEAN, statistical process control, queuing theory, and improvement science from Cincinnati Children's and the Institute for Health Care Improvement (IHI).
Dr. Iyer has also served as the improvement advisor for the National Pediatric Cardiology Quality Improvement Collaborative since 2006.
In December 2012, Dr. Iyer was offered a one year appointment in the CMS Innovation Advisors Program (IAP). His appointment is administered by the Oak Ridge Institute for Science and Education (ORISE) on behalf of the Centers of Medicare & Medicaid Services (CMS) Innovation Center.
MD: University of North Carolina School of Medicine, Chapel Hill, NC
MPH: Harvard School of Public Health
Residency: Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Fellowship: Pediatric Emergency Medicine, Cincinnati Children's Hospital Medical Center
Iyer SB, Anderson JB, Slicker J, Beekman RH, Lannon C. Using statistical process control to identify early growth failure among infants with hypoplastic left heart syndrome. World Journal for Pediatric and Congenital Heart Surgery. 2011.
Iyer SB, Schubert CJ, Schoettker PJ, Reeves SD. Use of quality-improvement methods to improve timeliness of analgesic delivery. Pediatrics. 2011 Jan;127(1):e219-25.
Mittiga M, Schwartz H, Iyer SB, Gonzalez J. Pediatric emergency residency experience: Requirement vs. reality. J Grad Med Educ. 2010; December; 2(4): 571-576.
Kulkarni AA, Weiss AA, Iyer SS. Detection of carbohydrate binding proteins using magnetic relaxation switches. Anal Chem. 2010 Sep 1;82(17):7430-5.
Kulkarni AA, Fuller C, Korman H, Weiss AA, Iyer SS. Glycan encapsulated gold nanoparticles selectively inhibit shiga toxins 1 and 2. Bioconjug Chem. 2010 Aug 18;21(8):1486-93.
Millen SH, Lewallen DM, Herr AB, Iyer SS, Weiss AA. Identification and characterization of the carbohydrate ligands recognized by pertussis toxin via a glycan microarray and surface plasmon resonance. Biochemistry. 2010 Jul 20;49(28):5954-67.
Brodzinski H, Iyer S, Grupp-Phelan J. Assessment of disparities in the use of anxiolysis and sedation among children undergoing laceration repair. Acad Pediatr. 2010 May-Jun;10(3):194-9.
Kulkarni AA, Weiss AA, Iyer SS. Glycan-based high-affinity ligands for toxins and pathogen receptors. Med Res Rev. 2010 Mar;30(2):327-93. Review.
Flagler MJ, Mahajan SS, Kulkarni AA, Iyer SS, Weiss AA. Comparison of binding platforms yields insights into receptor binding differences between shiga toxins 1 and 2. Biochemistry. 2010 Mar 2;49(8):1649-57.
Timm N, Iyer SB. Embedded earrings in children. Pediatric Emergency Care. 2008;24(1):1-3.
Robert S. Kahn, MD, MPH Associate Director, Division of General and Community Pediatrics
Associate Director, Division of General and Community Pediatrics
Physician Lead, Community and Population Health, James M. Anderson Center for Health System Excellence
Parental health as a mediator of poverty's effects on children; social and economic disparities in children's health; interaction of genes and environment in common childhood diseases
Robert S. Kahn, MD, MPH, is a general pediatrician and child health researcher. Dr. Kahn's main interest lies at the intersection of poverty and child health, trying to understand what leads to worse health among poor children, and where me might intervene most effectively. He focuses on the most common pediatric conditions such as asthma and Attention Deficit Hyperactivity Disorder (ADHD). His work includes both NIH-funded research, but also a focus on building practical collaborations with the most effective community agencies.
Dr. Kahn attended Princeton University and Vanderbilt University School of Medicine. At Children's Hospital in Boston, he completed his residency in pediatrics and a fellowship in primary care research. At the same time, he obtained a Masters in Public Health at Harvard School of Public Health.
Dr. Kahn came to Cincinnati Children's in 1999 as an assistant professor of pediatrics. Currently, he is a professor and associate director of the Division of General and Community Pediatrics. He now helps to direct the Community Health initiative in the Strategic Plan, and he is co-director of the Cincinnati Child-Health Law Partnership.
Moncrief TM, Beck AF, Simmons JM, Huang B, Kahn RS. Single parent households and increased child asthma morbidity. J Asthma. 2014 Apr;51(3)60-6.
Newman NC, Ryan PH, Huang B, Beck AF, Sauers HS, Kahn RS. Traffic-related air pollution and asthma hospital readmission in children: a longitudinal cohort study. J Pediatr. 2014 Mar 25.
Beck AF, Huang B, Simmons JM, Moncrief T, Sauers HS, Chen C, Ryan PH, Newman NC, Kahn RS. Role of financial and social hardships in asthma racial disparities. Pediatrics. 2014 Mar;133(3):431-9.
Klein MD, Alcamo AM, Beck AF, O'Toole JK, McLinden D, Henize A, Kahn RS. Can a video curriculum on the social determinants of health affect residents' practice and families' perceptions of care? Acad Pediatr. 2014 Mar-Apr;14(2):159-66.
Brown CM, Girio-Herrera E, Sherman SN, Kahn RS, Copeland KA. Pediatricians may address barriers inadequately when referring low-income preschool-aged children to behavioral health Services. J Health Care Poor Underserved. 2014 Feb;25(1):406-24.
Howrylak JA, Spanier AJ, Huang B, Peake RW, Kellogg MD, Sauers H, Kahn RS. Cotinine in children admitted for asthma and readmission. Pediatrics. 2014 Feb;133(2):e355-62.
DeMartini T, Beck AF, Kahn RS, Klein MD. Food insecure families: description of access and barriers to food from one pediatric primary care center. J Community Health. 2013 Dec;38(6):1182-7.
Goyal NK, Hall ES, Meinzen-Derr JK, Kahn RS, Short JA, Van Ginkel JB, Ammerman RT. Dosage effect of prenatal home visiting on pregnancy outcomes in at-risk, first-time mothers. Pediatrics. 2013 Nov;132 Suppl 2:S118-25.
Beck AF, Simmons JM, Sauers HS, Sharkey K, Alam M, Jones C, Kahn RS. Connecting at-risk inpatient asthmatics to a community-based program to reduce home environmental risks: care system redesign using quality improvement methods. Hosp Pediatr. 2013 Oct;3(4):326-34.
Chirdkiatgumchai V, Xiao H, Fredstrom BK, Adams RE, Epstein JN, Shah SS, Brinkman WB, Kahn RS, Froehlich TE. National Trends in Psychotropic Medication Use in Very Young Children: 1994-2009. Pediatrics. 2013 Oct;132(4):615-23.
Heather C. Kaplan, MD, MSCE Attending Neonatologist, Neonatology and Pulmonary Biology
Attending Neonatologist, Neonatology and Pulmonary Biology
Heather Kaplan conducts research focusing on understanding variations in evidence-based care practices across hospitals and examining strategies for increasing the implementation of evidence into practice in perinatal care. She uses a systems lens to understand and ultimately change behavior at the individual, group, organizational, and environmental levels of the health care system.
Kaplan HC, Lorch SA, Pinto-Martin J, Putt M, Silber JH. Assessment of surfactant use in preterm infants as a marker of neonatal intensive care unit quality. BMC Health Serv Res. 2011 Jan 31;11:22.
Kaplan HC, Brady PW, Dritz MC, Hooper DK, Linam WM, Froehle CM, Margolis P. The influence of context on quality improvement success in health care: a systematic review of the literature. Milbank Q. 2010 Dec;88(4):500-59.
Kaplan, HC, Tabangin ME, McClendon D, Meinzen-Derr J, Margolis PA, Donovan EF. Understanding Variation in Vitamin A Supplementation Among NICUs. Pediatrics. 2010 Aug;126(2):e367-73.
Jennifer L. Lail, MD Assistant Vice President, Chronic Care Systems, James M. Anderson Center for Health Systems Excellence
Assistant Vice President, Chronic Care Systems, James M. Anderson Center for Health Systems Excellence
Children with chronic and complex disease; quality improvement in health systems for chronic care
MD: University of KY College of Medicine, Lexington, KY, 1978.
Residency: Pediatrics, Duke University Medical Center, Durham NC, 1980-1981.
Residency: Pediatrics, Shands Teaching Hospital, Gainesville, FL, 1978-80.
Carole Lannon, MD, MPH Director, Learning Networks
Director, Learning Networks
Quality improvement; pediatrics
Lannon, CM, Peterson L, and Goudie A. Quality Measures for the Care of Children with Otitis Media with Effusion. Pediatrics. 2011;127:e1490-97.
Iyer S, Anderson JB, Slicker J, Beekman RH and Lannon CM. Using Statistical Process Control to Identify Early Growth Failure Among Infants with Hypoplastic Left Heart Syndrome. World Journal for Pediatric Congenital Heart Surgery. 2011;2(4):576-85.
Schidlow DN, Anderson JB, Klitzner TS, Beekman Iii RH, Jenkins KJ, Kugler JD, Martin GR, Neish SR, Rosenthal GL, Lannon C; For the JCCHD National Pediatric Cardiology Quality Improvement Collaborative. Variation in Interstage Outpatient Care after the Norwood Procedure: A Report from the Joint Council on Congenital Heart Disease National Quality Improvement Collaborative. Congenit Heart Dis. 2011 Mar;6(2):98-107.
Simpson LA, Peterson L, Lannon CM, Murphy SB, Goodman C, Ren Z, Zajicek A. Special challenges in comparative effectiveness research on children's and adolescents' health. Health Aff (Millwood). 2010 Oct;29(10):1849-56.
Donovan EF, Lannon C, Bailit J, Rose B, Iams JD, Byczkowski T; Ohio Perinatal Quality Collaborative Writing Committee. A statewide initiative to reduce inappropriate scheduled births at 360/7-386/7 weeks' gestation. Am J Obstet Gynecol. 2010 Jun;202(6):603.
Rothman RL, Yin HS, Mulvaney S, Co JP, Homer C, Lannon C. Health literacy and quality: focus on chronic illness care and patient safety. Pediatrics. 2009 Nov;124 Suppl 3:S315-26.
Kugler JD, Beekman RH, III, Rosenthal GL, Jenkins KJ, Klitzner TS, Martin G, Neish SR, Lannon C. Development of a pediatric cardiology quality improvement collaborative: from inception to implementation. Congenit Heart Dis 2009;4:318-328.
Lazorick S, Crowe V, Dolins J, Lannon CM. Structured Intervention Utilizing State Professional Societies to Foster Quality Improvement in Practice. J Continu Educ Health Prof. 2008; 28 (3): 131-9.
Lannon CM, Flower K, Duncan P, Moore KS, Stuart J, Bassewitz J. The Bright Futures Training Intervention Project: implementing systems to support preventive and developmental services in practice. Pediatrics. 2008 Jul;122(1):e163-71.
Center for Education, Research and Therapeutics: Pursuing Perfection in Pediatric Therapeutics, Agency for Healthcare Research and Quality. Principal Investigator. Sep 2011 - Sep 2016.
Communities Putting Prevention to Work. Principal Investigator. Centers for Disease Control, Hamilton County Health Department. Jul 2010 - Feb 2012.
Evaluation of an Intervention for Improving Community-Based Pediatric ADHD Care. Co-Investigator. National Institute of Health. Aug 2010 - July 2015.
Peter A. Margolis, MD, PhD Co-Director, Center for Health Care Quality
Co-Director, Center for Health Care Quality
Director of Research, James M. Anderson Center
Peter Margolis, MD, PhD, is professor of Pediatrics and director of Research at the James M. Anderson Center for Health System Excellence at Cincinnati Children’s Hospital Medical Center. His work encompasses the application and study of quality improvement methods in a broad range of areas including primary and sub-specialty care, communities and public health settings to improve the health outcomes of children, families and communities. Dr. Margolis obtained his MD from New York University and his pediatric training at the University of Colorado, where he also served as chief resident in Pediatrics. He subsequently spent three years in the National Health Service Corps in Rochester, NY, and Los Angeles, CA before pursuing a fellowship in clinical epidemiology. He was a Robert Wood Johnson Clinical Scholar at the University of North Carolina at Chapel Hill where he also earned his PhD in Epidemiology. In 1994, Dr. Margolis was named a Robert Wood Johnson Generalist Faculty Scholar at UNC where he also served on the faculty between 1991 and 2005. In 2006, Dr. Margolis' joined Cincinnati Children’s Hospital Medical Center to create a new center focused on Health Care Quality.
Dr. Margolis has worked extensively with the certifying Boards and Specialty Societies to assist them in designing programs that will enable physicians to meet new Maintenance of Certification requirements focused on systems thinking and performance in practice. He also devotes considerable time to teaching quality improvement methods. He is principle investigator of an NIH Roadmap transformative research grant on redesigning systems for chronic illness care.
Crandall W, Kappelman MD, Colletti RB, Leibowitz I, Grunow JE, Ali S, Baron HI, Berman JH, Boyle B, Cohen S, del Rosario F, Denson LA, Duffy L, Integlia MJ, Kim SC, Milov D, Patel AS, Schoen BT, Walkiewicz D, Margolis P. ImproveCareNow: The development of a pediatric inflammatory bowel disease improvement network. Inflamm Bowel Dis. 2011 Jan;17(1):450-7.
Kappelman MD, Crandall WV, Colletti RB, Goudie A, Leibowitz IH, Duffy L, Milov DE, Kim SC, Schoen BT, Patel AS, Grunow J, Larry E, Fairbrother G, Margolis P; on behalf of the ImproveCareNow Collaborative for Pediatric IBD. Short pediatric Crohn's disease activity index for quality improvement and observational research. Inflamm Bowel Dis. 2011 Jan;17(1):112-7.
Kaplan HC, Brady PW, Dritz MC, Hooper DK, Linam WM, Froehle CM, Margolis P. The influence of context on quality improvement success in health care: a systematic review of the literature. Milbank Q. 2010 Dec;88(4):500-59.
Margolis PA, DeWalt DA, Simon JE, Horowitz S, Scoville R, Kahn N, Perelman R, Bagley B, Miles P. Designing a large-scale multilevel improvement initiative: the improving performance in practice program. J Contin Educ Health Prof. 2010 Summer;30(3):187-96.
Kaplan HC, Tabangin ME, McClendon D, Meinzen-Derr J, Margolis PA, Donovan EF. Understanding variation in vitamin A supplementation among NICUs. Pediatrics. 2010 Aug;126(2):e367-73.
Miller MR, Griswold M, Harris JM 2nd, Yenokyan G, Huskins WC, Moss M, Rice TB, Ridling D, Campbell D, Margolis P, Muething S, Brilli RJ. Decreasing PICU catheter-associated bloodstream infections: NACHRI's quality transformation efforts. Pediatrics. 2010 Feb;125(2):206-13.
Margolis P, Halfon N. Innovation networks: a strategy to transform primary health care. JAMA. 2009 Oct 7;302(13):1461-2.
Colletti RB, Baldassano RN, Milov DE, Margolis PA, Bousvaros A, Crandall WV, Crissinger KD, D'Amico MA, Day AS, Denson LA, Dubinsky M, Ebach DR, Hoffenberg EJ, Kader HA, Keljo DJ, Leibowitz IH, Mamula P, Pfefferkorn MD, Qureshi MA. Pediatric IBD Network for Research and Improvement. Variation in care in pediatric Crohn disease. J Pediatr Gastroenterol Nutr. 2009 Sep;49(3):297-303.
Margolis P, Provost LP, Schoettker PJ, Britto MT. Quality improvement, clinical research, and quality improvement research--opportunities for integration. Pediatr Clin North Am. 2009 Aug;56(4):831-41.
Linam WM, Margolis PA, Staat MA, Britto MT, Hornung R, Cassedy A, Connelly BL. Risk factors associated with surgical site infection after pediatric posterior spinal fusion procedure. Infect Control Hosp Epidemiol. 2009 Feb;30(2):109-16.
Center for Education and Research in Therapeutics. Co-Investigator. Agency for Health Care Research and Quality. Sep 2007 – Aug 2011.
Transforming Early Childhood Systems. Co-Investigator. Kellogg Foundation. Apr 2009 – Mar 2012.
Open Source Science: Transforming Chronic Illness Care. National Institute of Diabetes & Digestion & Kidney Disease. Principal Investigator. Sep 2009 – Augu 2014.
Monica Mitchell, PhD Clinical Psychologist, Behavioral Medicine and Clinical Psychology
Clinical Psychologist, Behavioral Medicine and Clinical Psychology
Health disparities; sickle cell disease; obesity; community-based research; school-based mental health; qualitative research methods; using technology in psychological interventions and program evaluation; public policy
Visit the Mitchell Lab.
Monica Mitchell, PhD, received her doctorate from Vanderbilt University in 1998, and completed her residency and post-doctoral fellowship at Cincinnati Children’s Hospital Medical Center in 1998 and 2001 respectively. During her post-doctoral fellowship, she completed a supplement grant from the National Institutes of Health (NIH) - National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to examine family variables related to nutritional intake and mealtime behavior problems.
In 2001, Dr. Mitchell received a K01 grant to examine nutritional status and depression in children with sickle cell disease. This study was part of a five-year K01 career development grant she received from the National Institute of Mental Health (NIMH) that involves assessing growth, development and behavioral functioning in children with sickle cell disease.
Dr. Mitchell has published more than 20 articles, including in the Journal of Pediatric Psychology, Headache, Diabetes Care and Pediatrics. Dr. Mitchell has also served on the Journal of Pediatric Psychology's Editorial Board since 2005, and is past Chair of the Diversity Committee of the Society of Pediatric Psychology (Division 54 of the American Psychological Association). Most recently, she was appointed to a three year term to the Committee on Youth, Children and Families for APA.
PhD: Vanderbilt University, Nashville TN, 1999.
Pre-Doctoral Internship: Pediatric/Child Clinical Psychology, Cincinnati Children’s Hospital Medical Center, 1998.Post-Doctoral Fellowship: Division of Psychology, Cincinnati Children’s Hospital Medical Center, 2001.
Hines J, Crosby L, Harris A, Davis O, Mitchell M. Youth Engagement in Sickle Cell Disease Community Education. Health Behavior and Education. 2011.
Crosby L, Modi A, Mitchell M, Lemanek K, Kalinyak K. Adherence to clinic visits in adolescents with sickle cell disease. J Hem Onc. 2011.
Hines J, Mitchell M, Crosby L, Johnson A, Valenzuela J, Kalinyak K, Joiner C. Engaging Patients with Sickle Cell Disease and their Families in Disease Education, Research, and Community Awareness. J Prev Interv Comm. 2011.
Valenzuela J, Jacquez F, Pendery R, Niemes L, Huddleston D, Mitchell M. The Impact of a Community-based Activity and Nutrition Program for Children. J Prev Interv Comm. 2011.
Lynch J, Mitchell M. Community Engagement and the Ethics of Global, Translational Research: A Response to Sofaer and Eyal. Am J Bioeth. 2010 Aug;10(8):37-8.
Roberts Y, Mitchell M, Witman M, Taffarro C. Mental Health Symptoms in Youth Affected by Hurricane Katrina. Professional Psychology Research and Practice. 2010 Feb;41(1):10-18. Herzer M, Godiwala N, Hommel KA, Driscoll K, Mitchell M, Crosby LE, Piazza-Waggoner C, Zeller MH, Modi AC. Family functioning in the context of pediatric chronic conditions. J Dev Behav Pediatr. 2010 Jan;31(1):26-34.
McGrady ME, Mitchell MJ, Theodore SN, Sersion B, Holtzapple E. Preschool Participation and BMI at Kindergarten Entry: The Case for Early Behavioral Intervention. J Obes. 2010;2010. pii: 360407.
Mitchell MJ, Carpenter GJ, Crosby LE, Bishop CT, Hines J, Noll J. Growth status in children and adolescents with sickle cell disease. Pediatr Hematol Oncol. 2009 Jun;26(4):202-15.
Mitchell MJ, Piazza-Waggoner C, Modi A. Assessing Stability in Family Functioning in Cystic Fibrosis and Normative Samples Using the Mealtime Interaction Coding System. J Ped Psych. 2009;34(1):63-68.
Engaging Urban and Rural Appalachian Communities in Clinical Research. Site Principal Investigator. National Institutes of Health. Sep 2009 - Sep 2011.
Comprehensive Sickle Cell Center. Project Principal Investigator. National Institutes of Health. Apr 2008 - Mar 2012.
Clinical Translational Science Award. Co-Director. National Institutes of Health. Apr 2009 - Mar 2014.
Esi Morgan DeWitt, MD, MSCE
Childhood rheumatic diseases; juvenile idiopathic arthritis; juvenile dermatomyositis; sarcoidosis
Patient reported outcomes measure development; quality Improvement; health services research; economic evaluations; comparative effectiveness
MD: Washington University School of Medicine, St. Louis, MO, 1999.
Residency: Pediatrics, Children’s Hospital of Philadelphia, Philadelphia, PA, 2002.
Fellowship: Rheumatology, Children’s Hospital of Philadelphia, Philadelphia, PA, 2005.
MSCE: University of Pennsylvania, Center for Clinical Epidemiology & Biostatistics, Philadelphia, PA, 2005.
Certification: Pediatrics, 2002; Pediatric Rheumatology, 2006.
Dewitt EM, Stucky BD, Thissen D, Irwin DE, Langer M, Varni JW, Lai JS, Yeatts KB, Dewalt DA. Construction of the eight-item patient-reported outcomes measurement information system pediatric physical function scales: built using item response theory. J Clin Epidemiol. 2011 Jul;64(7):794-804.
Beukelman T, Patkar NM, Saag KG, Tolleson-Rinehart S, Cron RQ, DeWitt EM, et al. American College of Rheumatology recommendations for the treatment of juvenile idiopathic arthritis: initiation and safety monitoring of therapeutic agents for the treatment of arthritis and systemic features. Arthritis Care Res. 2011 Apr;63(4):465-82.
Dinan MA, Compton KL, Dhillon JK, Hammill BG, Dewitt EM, Weinfurt KP, Schulman KA. Use of patient-reported outcomes in randomized, double-blind, placebo-controlled clinical trials. Med Care. 2011 Apr;49(4):415-9.
Lovell DJ, Passo MH, Beukelman T, Bowyer SL, Gottlieb BS, Henrickson M, Ilowite NT, Kimura Y, DeWitt EM, Segerman J, Stein LD, Taylor J, Vehe RK, Giannini EH. Measuring process of arthritis care: a proposed set of quality measures for the process of care in juvenile idiopathic arthritis. Arthritis Care Res (Hoboken). 2011 Jan;63(1):10-6.
Varni JW, Stucky BD, Thissen D, Dewitt EM, Irwin DE, Lai JS, Yeatts K, Dewalt DA. PROMIS Pediatric Pain Interference Scale: An item response theory analysis of the Pediatric Pain Item Bank. J Pain. 2010 Nov;11(11):1109-19.
Irwin DE, Stucky BD, Thissen D, Dewitt EM, Lai JS, Yeatts K, Varni JW, DeWalt DA. Sampling plan and patient characteristics of the PROMIS pediatrics large – scale survey. Qual Life Res. 2010 May;19(4):585-94.
DeWitt EM, Lin L, Glick HA, Anstrom KJ, Schulman KA, Reed SD. Pattern and predictors of the initiation of biologic agents for the treatment of rheumatoid arthritis in the United States: an analysis using a large observational data bank. Clin Ther. 2009 Aug; 31(8):1871-80; discussion 1858.
Morgan DeWitt E, Glick HA, Albert DA, Joffe M, Wolfe F. Medicare coverage of tumor necrosis factor α inhibitors as an influence on physicians’ prescribing behavior. Arch of Intern Med. 2006;166:57-63.
DeWitt EM, Schanberg LE, Rabinovich CE. Treatment of Rheumatic Diseases. In RM Kleigman, BM Stanton, J St. Geme, N Schor, RE Behrman (Eds.), Nelson Textbook of Pediatrics. 19th ed. Elsevier Saunders: Philadelphia, PA, 2011.
Wu EY, DeWitt, EM. Sarcoidosis. In RM Kleigman, BM Stanton, J St. Geme, N Schor, RE Behrman (Eds.), Nelson Textbook of Pediatrics.19th ed. Elsevier Saunders: Philadelphia, PA, 2011.
Stephen E. Muething, MD Vice President for Safety, James M. Anderson Center for Health Systems Excellence
Vice President for Safety, James M. Anderson Center for Health Systems Excellence
Serious safety events reduction; high reliability organization theory; evidence-based care; family centered rounds; decreasing delays in discharge; clinical microsystems
Dr. Muething is vice president for safety at Cincinnati Children’s Hospital Medical Center, a lead faculty in the Anderson Center for Healthcare Transformation, and an associate professor of pediatrics. He leads the strategic goal of eliminating all serious harm for patients and employees. His improvement work and research focuses on high reliability culture, situation awareness and managing by prediction.
Dr Muething is also the clinical director of the Children’s Hospital Solution for Patient Safety. This network of more than 75 children’s hospitals, is collaborating to eliminate serious harm for all pediatric patients across the United States. He serves on multiple national pediatric safety groups and is a frequent consultant for regional, national and international safety initiatives. He spent the first decade of his clinical career building a pediatric practice and inpatient unit in rural Indiana. He then focused on inpatient systems at Cincinnati Children’s as a leader of the Hospital Medicine program and was at the forefront of multiple transformations in care delivery including family-centered rounds, systematic adoption of evidence-based practice and inpatient microsystems. Dr Muething continues his clinical work serving as a safety officer of the day at Cincinnati Children’s.
MD: University of Cincinnati, Cincinnati, OH, 1984.
Residency: Cincinnati Childrens Hospital Medical Center, Cincinnati, OH 1984-1987.
Stockwell DC, Kirkendall E, Muething SE, Kloppenborg E, Vinodrao H, Jacobs BR. Automated Adverse Event Detection Collaborative: Electronic Adverse Event Identification, Classification, and Corrective Actions Across Academic Pediatric Institutions. J Patient Saf. 2013 Dec;9(4):203-10.
Goldenhar LM, Brady PW, Sutcliffe KM, Muething SE. Huddling For High Reliability And Situation Awareness. BMJ Qual Saf. 2013 Nov;22(11)899-906.
Goldstein SL, Kirkendall E, Nguyen H, Schaffzin JK, Bucuvalas J, Bracke T, Seid M, Ashby M, Foertmeyer N, Brunner L, Lesko A, Barclay C, Lannon C, Muething S. Electronic Health Record Identification of Nephrotoxin Exposure and Associated Acute Kidney Injury. Pediatrics. 2013 Sep;132(3):e756-67.
Niedner MF, Muething SE, Sutcliffe KM. The High-Reliability Pediatric Intensive Care Unit. Pediatr Clin North Am. 2013 June;60(3):563-80.
Billett AL, Colletti RB, Mandel KE, Miller M, Muething SE, Sharek PJ, Lannon CM. Exemplar Pediatric Collaborative Improvement Networks: Achieving Results. Pediatrics. 2013 Jun; 131 Suppl 4:S196-203.
Kaminski GM, Britto MT, Schoettker PJ, Farber SL, Muething S, Kotagal UR. Republished: Developing Capable Quality Improvement Leaders. Postgrad Med J. 2013 Feb;89(1048): 78-86.
Kaminski GM, Britto MT, Schoettker PJ, Farber SL, Muething S, Kotagal UR. Republished: Developing Capable Quality Improvement Leaders. Postgrad Med J. 2013 Feb;89(1048):78-86.
Brady PW, Muething S, Kotagal U, Ashby M, Gallagher R, Hall D, Goodfriend M, White C, Bracke TM, Decastro V, Geiser M, Simon J, Tucker KM, Olivea J, Conway PH, Wheeler DS. Improving Situation Awareness To Reduce Unrecognized Clinical Deterioration And Serious Safety Events. Pediatrics. 2013 Jan;131(1):e298-308.
Kirkendall ES, Kloppenborg E, Papp J, White D, Frese C, Hacker D, Schoettker PJ, Muething S, Kotagal U. Measuring Adverse Events and Levels of Harm in Pediatric Inpatients with the Global Trigger Tool. Pediatrics. 2012 Nov;130(5):e1206-14.
Kaminski GM, Britto MT, Schoettker PJ, Farber SL, Muething S, Kotagal UR. Developing Capable Quality Improvement Leaders. BMJ Qual Saf. 2012 Nov;21(11):903-11.
Kieran J. Phelan, MD, MSc
General pediatrics; community-based preventative medicine; public health trials
Kieran Phelan, MD, MSc, is a board certified general pediatrician, an experienced injury epidemiologist and residential injury control researcher. He has been active in the fields of injury epidemiology and residential injury control for over 8 years.
His experience and success in this field includes multiple grants and publications, as well as the New Investigator Award from the National Center for Injury Prevention, control at the CDC, and an RO1-funded project. He has also has experience with the Cincinnati Home Injury Prevention (CHIP) and literacy promotion program and the National Institute of Child Health and Development (NICHD), which focuses on preventing injury and promoting literacy in a population of low-income mothers and their infants who were enrolled in a regional home visitation program. Lastly, he has experience with Every Child Succeeds (ECS), which tries to reduce residential injury and promote literacy in children from birth through 36 months of age.
BS: The University of Notre Dame, Notre Dame, IL, 1986.
MD: Northwestern University Medical School, Chicago, IL, 1991.
Residency: Children’s Memorial Hospital, Northwestern University Medical School, 1994.
MSc: Department of Epidemiology & Biostatistics, School of Environmental Health, 2001.
Certification: American Board of Pediatrics, 2008; Pediatric Advanced Life Support, 2009.
Frederick C. Ryckman, MD Professor of Surgery / Transplantation
Professor of Surgery / Transplantation
Sr. Vice President, Medical Operations
Professor, UC Department of Surgery
Transplantation; liver; kidney transplantation; small intestine; biliary disease; Extracorporeal membrane oxygenation (ECMO); minimally invasive surgery; chest wall abnormalities
Frederick C. Ryckman, MD, is clinical director of the Pediatric General and Thoracic Surgery Division.
Dr. Ryckman is also vice president of System Capacity & Perioperative Operations.
Dr. Ryckman is also a pediatric surgeon at the Cincinnati Fetal Center.
Wagner LM, Gelfand MJ, Laor T, Ryckman FC, Al-Ghawi H, Bove KE. A Welcome Surprise: Nodular Fasciitis Presenting as Soft Tissue Sarcoma. J Pediatr Hematol Oncol. 2010 Oct 21.
Taylor JA, Ryckman FC. Management of small bowel volvulus around feeding Roux-en-Y limbs. Pediatr Surg Int. 2010 Apr;26(4):439-42.
Rattan AS, Laor T, Ryckman FC, Brody AS. Pectus excavatum imaging: enough but not too much. Pediatr Radiol. 2010 Feb;40(2):168-72.
Propst EJ, Lin EP, Istaphanous GK, Boesch RP, Ryckman FC, Cotton RT, Rutter MJ. Management of traumatic tracheobronchial separation in a teenager using a fabricated extra-long endotracheal tube. Int J Pediatr Otorhinolaryngol. 2009 Aug;73(8):1163-7.
Dickie B, Dasgupta R, Nair R, Alonso MH, Ryckman FC, Tiao GM, Adams DM, Azizkhan RG. Spectrum of hepatic hemangiomas: management and outcome. J Pediatr Surg. 2009 Jan;44(1):125-33.
Ryckman FC, Bucuvalas JC, Nathan J, Alonso M, Tiao G, Balistreri WF. Outcomes following liver transplantation. Semin Pediatr Surg. 2008 May;17(2):123-30.
Nathan JD, Rudolph JA, Kocoshis SA, Alonso MH, Ryckman FC, Tiao GM. Isolated liver and multivisceral transplantation for total parenteral nutrition-related end-stage liver disease. J Pediatr Surg. 2007 Jan;42(1):143-7.
Michael Seid, PhD Director, Health Outcomes and Quality Care Research, Pulmonary Medicine and James M. Anderson Center for Health Systems Excellence
Director, Health Outcomes and Quality Care Research, Pulmonary Medicine and James M. Anderson Center for Health Systems Excellence
Health care quality / outcomes
Visit the Seid Lab.
Michael Seid, PhD, is director of Health Outcomes and Quality of Care Research in the Division of Pulmonary Medicine and a core faculty in the James M. Anderson Center for Health Systems Excellence at Cincinnati Children's Hospital Medical Center. Dr. Seid applies behavioral and social science to the question ‘What does it take to make sure the right treatment gets to the right child in the right way at the right time, every time?’
Dr. Seid has worked at the Center for Child Health Outcomes at Children's Hospital, San Diego and was a behavioral / research scientist at the RAND Corporation. He has been principal and co-principal investigator of several large multidisciplinary research studies, collaborates with investigators at Cincinnati Children's and beyond, and publishes widely in such journals as Medical Care, HSR: Health Services Research, Archives of Pediatrics and Adolescent Medicine, Pediatrics, American Journal of Medical Quality, the Journal of Ambulatory Pediatrics, and Milbank Quarterly.
Dr. Seid has served as the chair of Children's Hospital San Diego's Institutional Review Board, as a member of the Health Care Quality and Effectiveness Research (HCQER) Study Section at the Agency for Healthcare Quality and Research, and on several national and local expert panels. He is on the Review Board of the Journal of Clinical Outcomes Management and an ad hoc reviewer for Health Services Research, Pediatrics and the Journal of Ambulatory Pediatrics.
Grossoehme DH, Ragsdale JR, Snow A, Seid M. We were Chosen as a Family: Parents' Evolving Use of Religion when Their Child has Cystic Fibrosis. J Relig Health. 2011 Mar 16.
McPhail GL, Weiland J, Acton JD, Ednick M, Chima A, VanDyke R, Fenchel MC, Amin RS, Seid M. Improving evidence-based care in cystic fibrosis through quality improvement. Arch Pediatr Adolesc Med. 2010 Oct;164(10):957-60. Muething SE, Conway PH, Kloppenborg E, Lesko A, Schoettker PJ, Seid M, Kotagal U. Identifying causes of adverse events detected by an automated trigger tool through in-depth analysis. Qual Saf Health Care. 2010 Oct;19(5):435-9.
Grossoehme DH, Ragsdale J, Cotton S, Wooldridge JL, Grimes L, Seid M. Parents' religious coping styles in the first year after their child's cystic fibrosis diagnosis. J Health Care Chaplain. 2010 Jul;16(3-4):109-22.
Grossoehme DH, Ragsdale J, Wooldridge JL, Cotton S, Seid M. We can handle this: parents' use of religion in the first year following their child's diagnosis with cystic fibrosis. J Health Care Chaplain. 2010 Jul;16(3-4):95-108.
Stevens GD, Seid M, Pickering TA, Tsai KY. National disparities in the quality of a medical home for children. Matern Child Health J. 2010 Jul;14(4):580-9.
Ernst MM, Wooldridge JL, Conway E, Dressman K, Weiland J, Tucker K, Seid M. Using Quality Improvement Science to Implement a Multidisciplinary Behavioral Intervention Targeting Pediatric Inpatient Airway Clearance. J Pediatr Psychol. 2010 Jan-Feb; 35(1):1.
Seid M, Limbers CA, Driscoll KA, Opipari-Arrigan LA, Gelhard LR, & Varni JW. Reliability, validity, and responsiveness of the Pediatric Quality of Life Inventory™ (PedsQL™) Generic Core Scales and Asthma Symptoms Scale in vulnerable children with asthma. Journal of Asthma. 2010;47:170-177.
Wirtschafter DD, Pettit J, Kurtin P, Dalsey M, Chance K, Morrow HW, Seid M, Byczkowski TL, Huber TP, Milstein JM, Bowles SM, Fichera S, Kloman S. A statewide quality improvement collaborative to reduce neonatal central line-associated blood stream infections. J Perinatol. 2010 Mar;30(3):170-81. Epub 2009 Nov 26.
Fairbrother G, Cassedy A, Ortega-Sanchez IR, Szilagyi PG, Edwards KM, Molinari NA, Donauer S, Henderson D, Ambrose S, Kent D, Poehling K, Weinberg GA, Griffin MR, Hall CB, Finelli L, Bridges C, Staat MA; New Vaccine Surveillance Network (NVSN). High costs of influenza: Direct medical costs of influenza disease in young children. Vaccine. 2010 Jul 12;28(31):4913-9.
Heather L. Tubbs Cooley, PhD, RN Nurse Scientist, Center for Professional Excellence
Nurse Scientist, Center for Professional Excellence
Assistant Professor, UC College of Nursing
Dr. Heather Tubbs Cooley, PhD, RN, is an assistant professor and nurse scientist at Cincinnati Children’s Hospital Medical Center and an assistant professor of clinical nursing at the University of Cincinnati College of Nursing. Her research focuses on relationships between the delivery of inpatient care and patient, nurse and systems outcomes. She was the recipient of a T32 training fellowship at the University of Pennsylvania and received a Dissertation Award from the Agency for Healthcare Research and Quality in 2010 for her doctoral research examining the impact of nurses’ working conditions on length of stay and readmission for hospitalized children. In 2011, she received the New Investigator Award from the AcademyHealth Interdisciplinary Research Group on Nursing Issues.
Dr. Tubbs Cooley is a member of several professional organizations and research networks including AcademyHealth, the Council for the Advancement of Nursing Science, the Midwest Nursing Research Society, the Academy for Healthcare Improvement, and the Pediatric International Patient Safety and Quality Community.
PhD: University of Pennsylvania, Philadelphia, PA, 2010.
MS: University of Pennsylvania, Philadelphia, PA, 2006.
BS: Western Michigan University, Kalamazoo, MI, 2003.
Fellowship: Quality Scholars Program in Health Systems Transformation, Cincinnati Children’s Hospital Medical Center, 2011-present.
Pickler RH, McGrath J, Reyna B, Tubbs-Cooley HL, Lewis M, Best A, Wetzel P, McGrath J, Cone S. Effects of NICU environmental characteristics on preterm infant oral feeding. Research and Reports in Neonatology. Epub ahead of print. 2013.
Tubbs-Cooley HL, Lynn J. From research to policy: Contracting for quality improvement research. Implement Sci. Epub ahead of print. 2013.
Tubbs-Cooley HL, Munro C, Pickler RH. Issues in research integrity: Deciding what is mine, yours, and ours. J Ped Health Care. 2012;26(5):370-373.
Tubbs Cooley H, Santucci G, Kang TI, Feinstein JA, Hexam KR, Feudtner C. Pediatric nurses’ individual and group assessments of palliative, end-of-life, and bereavement care. J Palliat Med. 2011 Apr.
Missed Nursing Care and Infant Outcomes in the Neonatal Intensive Care Unit. Principle Investigator. Cincinnati Children’s Hospital Medical Center Research Scholar in Patient Services Award. Jul 2012 - Jun 2014.
Patterned Experience for Preterm Infants. Collaborator (data quality and extraction). NIH/NINR. Mar 2011 - Feb 2015. 1R01 NR012307.
Kathleen E. Walsh, MD, MSc Director of Patient Safety Research, James M. Anderson Center for Health Systems Excellence
Director of Patient Safety Research, James M. Anderson Center for Health Systems Excellence
Pediatric hospital medicine
Patient safety; medication use; adverse drug events; quality improvement; chronic disease care; home care
Dr. Walsh is director of patient safety research and associate professor of pediatrics at Cincinnati Children’s. She has extensive experience in the qualitative and quantitative measurement of medication errors and adverse drug events among children in the hospital, clinic, and home. She has performed several studies of medication use in the homes of children with chronic conditions. She has developed and evaluated health information technology interventions to support medication use. Dr. Walsh is a general pediatrician with clinical research fellowship training, including a Masters in Epidemiology.
With funding from the Robert Wood Johnson Foundation, Dr. Walsh developed methods to measure mistakes in home medication use, using home visits. She visited the homes of children with sickle cell disease, cancer, and epilepsy in single site and multisite studies to quantify and describe errors. She also led failure modes and effects analyses with parents of children with cancer to identify failures in home medication use. In collaboration with parents of children with chronic conditions, she has participated in the development, implementation, and testing of information technology interventions to improve home medication use. Her research has been funded by the Food and Drug Administration, the National Institutes of Health, the Agency for Healthcare Research and Quality, and the Robert Wood Johnson Foundation.
Undergraduate: Cornell University, Ithaca, NY, 1992.
MD: Georgetown Medical School, Washington DC, 1998.
Residency: Pediatrics, Brown Medical School, 2001.
Chief Residency: Pediatrics, Brown Medical School, 2002.
Fellowship: General Academic Pediatrics, Boston University School of Medicine, 2005.
Master of Science: Epidemiology, Boston University School of Public Health, 2005.
Walsh KE, Cutrona SL, Foy S, Baker MA, Forrow S, Shoaibi A, Pawloski PA, Conroy M, Fine AM, Nigrovic LE, Selvam N, Selvan MS, Cooper WO, Andrade S. Validation of Anaphylaxis in the Food and Drug Administration’s Mini-Sentinel. Pharmacoepidemiology and Drug Safety. In press.
Walsh KE, Roblin DW, Weingart SN, Houlahan SN, Degar B, Billett A, Keuker C, Biggins C, Li J, Wasilewski K, Mazor KM. Medication errors in the home: A multisite study of children with cancer. Pediatrics. 2013;131:e1405-e1413.
Bradley CK, Fischer MA, Walsh KE. Trends in Medical Error Education: Are We Failing Our Residents?Academic Pediatrics. 2012;13:59-64.
Walsh KE, Mazor KM, Roblin D, Biggins C, Wagner JL, Houlahan K, Li J, Keuker C, Wasilewski-Masker K, Donovan J, Kanaan A, Weingart SN. A Multisite Parent-Centered Risk Assessment to Reduce Pediatric Oral Chemotherapy Errors. Journal of Oncology Practice. 2013;9(1):e1-e7.
Walsh KE, Mazor KM, Stille CJ, Torres I, Wagner JL, Moretti J, Chysna K, Stine CD, Usmani GN, Gurwitz JH. Medication Errors in the Homes of Children with Chronic Conditions. Archives of Disease in Childhood. 2011;6:581-6.
Mazor KM, Goff SL, Dodd K, Venton S, Walsh KE. Parents Perceptions of Medication Errors. Journal of Patient Safety. 2010;6:102-107.
Walsh KE, Dodd KS, Seetharaman K, Roblin DW, Herrinton LJ, Von Worley A, Usmani GN, Baer D, Gurwitz JH. Medication Errors among Adults and Children with Cancer in the Outpatient Setting. Journal of Clinical Oncology. 2009. 27: 891-6.
Walsh KE, Stille CJ, Mazor KM, Gurwitz JH. Using home visits to understand medication errors in children. In: Henriksen K., Battles JB, Keyes MA, Grady ML, eds. Advances in Patient Safety: New Directions and Alternative Approaches. Vol. 4: Technology and Medication Safety. AHRQ Pub. No. 08-0034-4. Rockville, MD: Agency for Healthcare Research and Quality; 2008.
Sard BE, Walsh KE, Doros G, Hannon M, Moschetti W, Bauchner H. A Retrospective Evaluation of a Computerized Physician Order Entry Adaptation to Prevent Prescribing Errors in a Pediatric Emergency Department. Pediatrics. 2008. 122 (4): 782-7.
Walsh KE, Landrigan CP, Adams WG, Vinci RJ, Chessare JB, Cooper MR, Hebert PH, Schainker EG, Bauchner H. Medication Errors Caused by Computer Order Entry. Pediatrics. 2008; 121(3): e4.
Denise L. White, PhD, MBA Efficiency/Productivity Consultant, Quality and Transformation Analytics, James M. Anderson Center for Health Systems Excellence
Efficiency/Productivity Consultant, Quality and Transformation Analytics, James M. Anderson Center for Health Systems Excellence
Denise White, PhD, MBA, is an assistant professor and efficiency/productivity consultant in quality and transformation analytics in the James M. Anderson Center for Health Systems Excellence at Cincinnati Children’s Hospital Medical Center. Dr. White is a graduate from the University of Cincinnati’s College of Business where she received her PhD in operations management with a focus on healthcare operations. She holds a BS degree in mathematics and computer science and has secured her master’s in business administration (MBA) along with a certification as a project management professional (PMP). Dr. White’s research interests lie in the area of capacity management, hospital flow, and scheduling. She has participated in efforts to improve resource utilization across the organization and partners with the University of Cincinnati to deliver graduate and undergraduate courses in healthcare operations management.
BS: Computer Science and Mathematics, Wilmington College, Wilmington, OH, 1987.
MBA: Northern Kentucky University, Highland Heights, KY, 1995.
Master's Certification: Project Management, George Washington University, Steven's Institute of Technology, Washington, DC, 1997.
PhD: Business (Operations Management), College of Business, University of Cincinnati, 2010.
Froehle CM, White DL. Interruptions and Forgetting in Knowledge Intensive Service Environments. Production and Operations Management. 2013 18 Oct;1-19.
Kirkendall ES, Kloppenborg E, Papp J, White D, Frese C, Hacker D, Schoettker PJ, Muething S, Kotagal U. Measuring adverse events and levels of harm in pediatric inpatients with the Global Trigger Tool. Pediatrics. 2012 Nov;130(5):e1206-14.
White DL, Froehle CM, Klassen K. The Effect of Integrated Scheduling and Capacity Policies on Clinical Efficiency. Production and Operations Management. 2011;20(3): 442-455.
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